3M ESPE
TM
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Vanish
TM
5% Sodium Fluoride White Varnish
with Tri-Calcium Phosphate
NPN80003435
Enhancing
Protection and Performance
with our exclusive
Tri-Calcium Phosphate
3M ESPE’s popular varnish treatment
keeps getting better! Now with TCP.
TCP (Protected CaOn)
3M ESPE’s exclusive TCP offers
more protection.
Fluoride
3M ESPE Vanish 5% Sodium Fluoride White Varnish with
Tri-Calcium Phosphate (TCP) is a proprietary formula that
contains fluoride, calcium and phosphate - components naturally
found in saliva. This exclusive TCP technology has been
customized to work with Vanish White Varnish to deliver
targeted and sustained fluoride and calcium release.
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During the manufacturing process, a protective barrier is
created around the calcium allowing it to coexist with the
fluoride. After application, Vanish White Varnish with TCP
flows across tooth surfaces and comes in contact with saliva,
releasing calcium and fluoride.
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As the varnish moves, more varnish material is exposed to
saliva allowing additional fluoride and calcium to be released
on the tooth surface. This process enables Vanish White
Varnish with TCP to continuously release fluoride AND calcium
over the life of the varnish - up to 24 hours! Vanish White
Varnish with TCP penetrates and seals dentin tubules providing
immediate and long-lasting occlusion.
Saliva activates the protected
calcium compound at the tooth
surface, causing it to be released
together with fluoride.
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Varnish coating
Tooth
Saliva
Vanish White Varnish with TCP enters and blocks tubules.
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Vanish 5% Sodium Fluoride White
Varnish with TCP fully covers and
occludes open tubules.
Source: 3M ESPE internal data.
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SEM image at 1500X
magnification
Borg penetrates tubules (top view)
After the bulk of the varnish has been removed
from the surface, Vanish 5% Sodium Fluoride
White Varnish with TCP continues to block tubule
openings for long-lasting protection.
Source: 3M ESPE internal data.
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SEM image at 1500X
magnification
Easy for you to use.
A better experience for your patients.
Fluoride treatment has to be convenient. Vanish 5% Sodium Fluoride White Varnish
with our innovative TCP is simple to use and comfortable to wear. 3M ESPE
formulated Vanish White Varnish with TCP so that the area to be treated needs to be
only “toothbrush cleaned” and excess saliva removed - no complicated pretreatment is
necessary. It can even be applied if plaque is present.
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Protection you can’t see.
Vanish White Varnish with TCP is virtually invisible on the
teeth - but leaves a temporary thin coating so patients
know it’s working.
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Plus, it offers other great advantages.
• The application takes just seconds.
• The patient can eat and drink immediately following the application.
• The colour is similar to enamel, so it’s virtually invisible.
• Available in Cherry, Melon or Mint flavours; sweetened with xylitol.
Immediately after Vanish 5% Sodium Fluoride White
Varnish with TCP was applied.
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Applying 3M ESPE Vanish White Varnish with TCP is easy and it takes just seconds.
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Simply apply one thin coat, sweeping the brush across tooth surfaces - and the VanishTM White Varnish with TCP formula does the rest.
• Sets in the presence of saliva - no drying needed.
• Enhanced flow characteristics allow Vanish White Varnish with TCP to reach interproximal areas other varnishes may miss.
Mean Number of Tooth Surfaces
• Covers and adheres to the areas where applied.
where Varnish was Reported
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Open the unit
3
_SEM; n=20)
(+
dose package of
Vanish White
Varnish
with Surfaces
TCP20.0
Mean Number
of Tooth
and mix.
where Varnish
was Reported
2
Apply Vanish White
Varnish with TCP evenly
in a thin layer over
treatment area(s) with
sweeping, horizontal
brush strokes.
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10.0
Competitive
5% NaF Varnish
Number of Tooth Surfaces
20.0
15.0
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_SEM; n=20)
(+
3M ESPE Vanish 5%
Sodium Fluoride White Varnish
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Number of Tooth Surfaces
The tooth surface(s)
to be treated
should minimally
be “toothbrush
cleaned” and excess
saliva removed. Can
be applied in the
presence of plaque.
1
10.0
5.0
0.0
0.0
1 Hour Assessment Time (post-application)
Competitive
5% NaF Varnish
Vanish™ 5% Sodium Fluoride
White Varnish
Flows better and reaches areas
traditional varnishes may miss.
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After application, instruct the patient to close his or her mouth to set the Vanish White Varnish with TCP. 5.0
Do not use suction.
Please refer to Instructions For Use for more detailed information, as well
15.0as precautionary and warranty information.
Delivers more fluoride.
Salivary
Because of thisMean
ability
to flowFluoride
across and between teeth, more
more fluoride is
released in(+_the
mouth
compared
to
competitive
varnish tested.
SEM; n=20)
1 Hour
1 Hour Assessment
Time Concentration
(post-application)
varnish reaches
more tooth after
surfaces
- and
How does Vanish White Varnish with TCP get into the hard-to-reach places? It
flows better than other varnishes tested, and doesn’t just harden and stop where
applied. Vanish White Varnish with TCP remains fluid longer, and continues to
Mean Salivary Fluoride Mean Fluoride Concentration After 1 Hour
flow from treated to untreated tooth surfaces - including interproximal areas.
Concentration after 1 Hour 8.0
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6.0
5.0
ppm F
1 cm
3.0
Vanish™ 5% Sodium Fluoride
White Varnish
0 cm
2 cm
3 cm
4.0
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1.0
0.0
Competitive
5% NaF Varnish
Flow measured as 8.0
the vertical distance
7.0
Vanish 5% Sodium
6.0
Fluoride White Varnish
with TCP travels in 5.0
the presence of water
4.0
after initial application
over time.
3.0
Source: 3M ESPE
2.0
internal data.
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5 min.
2.0
1.0
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1 min.
0.0
Competitive
5% NaF Varnish
10 sec.
ppm F
0 sec.
7.0
_SEM; n=20)
(+
3M ESPE Vanish 5%
Sodium Fluoride White Varnish
Vertical Flow Test
Clinical test shows Vanish 5% Sodium Fluoride White Varnish with
TCP provides higher average salivary fluoride levels in-vivo.
Source: 3M ESPE internal data.
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Releases calcium.
Clinical studies show that Vanish White Varnish
with TCP
flows
to more
thanSurfaces
twice as many tooth
Mean
Number
of Tooth
surfaceswhere
after application.
Varnish was Reported
Products that provide both fluoride 0.8
and calcium are designed to help increase formation of
calcium fluoride on tooth surfaces, 0.7
including dentin tubules, strengthening tooth structure.
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mcg Ca/cm2 Coating, Cumulative
Covers more tooth surfaces.
Cumulative Calcium Release
Cumulative Calcium Release0.6
Cumulative Calcium
Release
0.5
Flow Test - After 1 Hour
3M ESPE Vanish 5%
Sodium Fluoride White Varnish
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10.0
5.0
0.0
Competitive
5% NaF Varnish
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15.0
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Number of Tooth Surfaces
20.0
1 Hour Assessment Time (post-application)
Vanish 5% Sodium Fluoride White Varnish with TCP was applied
to 8 anterior maxillary surfaces in-vivo. After application, it
MeantheSalivary
Fluoride hard-to-reach places.
moves across
teeth, penetrating
Concentration
Source: 3M
ESPE internal after
data. 1 Hour
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_SEM; n=20)
(+
0.8
mcg Ca/cm2 Coating, Cumulative
_SEM;
(+
n=20) Varnish
In-Vivo
0.7
0.6
0.5
0.4
0.3
0.4
0.2
0.1
0.0
After application,
Vanish 5% Sodium
Fluoride White Varnish
with TCP continues to
release calcium ions
15over at least
20 24 hours.
25
Source: 3M ESPE
Hours
internal data.
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0.3
5
0
10
0.2
0.1
0.0
0
5
10
15
Hours
Five Years
20
25
of Clinical
30
Success.
30
Better protection made easier from 3M ESPE…
a leader in preventive care solutions.
3M ESPE Vanish White Varnish with TCP
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• NEW optimized formula containing fluoride, calcium and phosphate.
• Aids in the prevention of cavities by delivering 22,600 ppm of fluoride.
• Moves across tooth surfaces, penetrating hard to reach places,
including interproximally.
• Takes just seconds to paint on - and goes on white, so it’s
virtually invisible.
• Sweetened with Xylitol, which reduces the risk for tooth decay.
• Three delicious flavours to choose from: Cherry, Melon, Mint
• Exhibits high salivary fluoride levels.
• Five years of clinical success.
Preventive products with our exclusive calcium-based technologies help
protect tomorrow’s smiles.
3M ESPE Vanish 5% Sodium
Fluoride White Varnish with TCP
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Our exclusive TCP ingredient delivers more protection.
3M ESPE Clinpro 5000 1.1%
Sodium Fluoride Anti-Cavity
Toothpaste
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Delivers more fluoride. Helps strengthen enamel and
reverses white spot lesions.
3M ESPE Vanish XT
Extended Contact Varnish
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Immediately relieves sensitivity by blocking dentin
tubules and delivers fluoride for 6 months or longer.
Ordering Information
NPN80003435
Item #
Product Information
12154C
Vanish 5% Sodium Fluoride White Varnish 100 Pack - Cherry Flavour
12154L
Vanish 5% Sodium Fluoride White Varnish 100 Pack - Melon Flavour
12154M
Vanish 5% Sodium Fluoride White Varnish 100 Pack - Mint Flavour
12215
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Includes: 100 unit dose blister packets (0.5 mL each); 100 applicator brushes; 2 patient pads; 100 dosage stickers; Technique Card
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Includes: 100 unit dose blister packets (0.5 mL each); 100 applicator brushes; 2 patient pads; 100 dosage stickers; Technique Card
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Includes: 100 unit dose blister packets (0.5 mL each); 100 applicator brushes; 2 patient pads; 100 dosage stickers; Technique Card
Clinpro 5000 1.1% Sodium Fluoride Anti-Cavity Toothpaste
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4 oz. (113 g) tube, Vanilla Mint flavour
12148
Vanish XT Extended Contact Varnish
NPN80012416
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1 – 10 g ClickerTM Dispenser
For protection you can’t see... our exclusive TCP!
Customer Care Centre: 1-888-363-3685 www.3MESPE.ca
Dental Products
3M Canada
Post Office Box 5757
London, Ontario N6A 4T1
1-888-363-3685
www.3MESPE.ca
3M Center
Building 275-2SE-03
St. Paul, MN 55144-1000
USA
1-800-634-2249
3M ESPE AG
Dental Products
D-82229 Seefeld - Germany
© 2010, 3M. All rights reserved. 3M, ESPE, Clicker, Clinpro and
Vanish are trademarks of 3M or 3M ESPE AG. Used under license
in Canada. 1006-01789 E