Lecture 12 Basics: Cell cycle and mitosis Cell division Responsible for: Also results in the uncontrolled growth of: The cell cycle Vocabulary: Lecture 12 Page 1 Duplicated Chromosomes Haploidy and diploidy Lecture 12 Page 2 Homologous vs sister chromatids More Vocabulary Condensation: Lecture 12 Page 3 Karyotype 13.3 Phases of Mitosis Lecture 12 Page 4 Kinetochores and spindle fibers Lecture 12 Page 5 Class Notes The following diagram will help you track the movement of chromosomes through synthesis and meiosis. Stage How many Chromosomes chromosomes? look like: Cells in G1 How many homologous pairs? 46 How many sister chromatids? Ploidy? 2n or n 0 2n In G2 Metaphase of mitosis Daughter cells In groups, draw three cells with 2n = 6 in the following stages: Metaphase G1 G2 Lecture 12 Page 6 Phosphodiester bonds are formed during: A. G1 phase B. S phase C. G2 phase D. M phase Which of the following does NOT occur during mitosis? A. Replication of DNA B. Separation of sister chromatids C. Breakdown of the nuclear membrane 50 DNA Content (arbitrary units) The DNA content of nerve cells at G1, mature sperm, and gut endothelial cells at G2 have been measured and plotted on the graph below. Based on the data in the graph, which DNA sample is the nerve cell? A. Sample 1 B. Sample 2 C. Sample 3 40 30 20 10 0 1 2 3 Sample Lecture 12 Page 7
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