2014

Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony–forming cells
O'Neill, C. L. , Medina, R. J. , Stitt, A. W. & 21 others Nov 2014 In : Nature Biotechnology. 32, 11, p. 1151-1157
Angiogenic Potential of Vitreous from Proliferative Diabetic Retinopathy and Eales' Disease Patients
Murugeswari, P., Shukla, D., Kim, R., Namperumalsamy, P., Stitt, A. W. & Muthukkaruppan, V. 13 Oct 2014 In : PloS one. 9,10, p.
e107551
Pathophysiology and Pathogenesis of Diabetic Retinopathy
Xu, H., Curtis, T. & Stitt, A. Aug 2014 Diapedia, The Living Textbook of Diabetes [internet].
Precise activation of EC-regulatory-networks underpinning direct reprogramming of vascular endothelial cells for use in
regenerative medicine
Kelaini, S., Cochrane, A., Grieve, D., Stitt, A. & Margariti, A. Jun 2014
Endothelial progenitor cells in diabetic retinopathy
Lois, N., McCarter, R. V., O'Neill, C., Medina, R. J. & Stitt, A. W. Apr 2014 In : Frontiers in endocrinology. 5, 44. , 44
RAGE Regulates Immune Cell Infiltration and Angiogenesis in Choroidal Neovascularization
Chen, M., Glenn, J. V., Dasari, S., McVicar, C., Ward, M., Colhoun, L., Quinn, M., Bierhaus, A., Xu, H. & Stitt, A. W. 26 Feb 2014 In
: PloS one. 9, 2, e89548. , e89548
Modelling fatigue of bone cement
Lennon, A. 08 Apr 2014 Computational modelling of biomechanics and biotribology in the musculoskeletal system. Jin, Z. (ed.). 1
ed. Woodhead Publishing, p. 305-330
Peripheral neuropathy may be a potential risk of cardiovascular disease in diabetes mellitus
Margariti, A. Dec 2014 In : Heart (British Cardiac Society). 100, 23, p. 1823-1824
Unspliced X-box-binding Protein 1 (XBP1) Protects Endothelial Cells from Oxidative Stress through Interaction with Histone
Deacetylase 3*
Martin, D., Li, Y., Yang, J., Wang, G., Margariti, A., Jiang, Z., Yu, H., Zampetaki, A., Hu, Y., Xu, Q. & Zeng, L. 04 Sep 2014 In :Journal
of Biological Chemistry. 289, p. 30625-30634
Precise activation of EC-regulatory-networks underpinning direct reprogramming of vascular endothelial cells for use in
regenerative medicine
Kelaini, S., Cochrane, A., Grieve, D., Stitt, A. & Margariti, A. Jun 2014
Macrophages Control Vascular Stem/Progenitor Cell Plasticity Through Tumor Necrosis Factor-α–Mediated Nuclear Factor-κB
Activation
Wong, M. M., Chen, Y., Margariti, A., Winkler, B., Campagnolo, P., Potter, C., Hu, Y. & Xu, Q. Mar 2014 In : Arteriosclerosis
Thrombosis and Vascular Biology. 34, 3, p. 635-643
Direct reprogramming of adult cells: avoiding the pluripotent state
Kelaini, S., Cochrane, A. & Margariti, A. Feb 2014 In : Stem cells and cloning : advances and applications. 7, p. 19-29
Expression pattern of arenicins—the antimicrobial peptides of polychaete Arenicola marina
Maltseva, A., Kotenko, O., Kokryakov, V., Starunov, I. & Krasnodembskaya, A. 19 Dec 2014 In : Frontiers in Physiology.120063. ,
120063
Simvastatin in the Acute Respiratory Distress Syndrome
McAuley, D. F., Laffey, J. G., O'Kane, C. M., Perkins, G. D., Mullan, B., Trinder, T. J., Johnston, P., Hopkins, P. A., Johnston, A. J.,
McDowell, C., McNally, C. & the HARP-2 Investigators, for the Irish Critical Care Trials Group 30 Oct 2014 In : New England Journal
of Medicine. 371, p. 1695-1703
SMAD inhibition attenuates epithelial to mesenchymal transition by primary keratinocytes in vitro
O'Kane, D., Jackson, M. V., Kissenpfennig, A., Spence, S., Damkat-Thomas, L., Tolland, J. P., Smyth, A. E., Denton, C. P., Elborn, J. S.,
McAuley, D. F. & O'Kane, C. M. Jul 2014 In : Experimental dermatology. 23, 7, p. 497-503
Keratinocyte Growth Factor Promotes Epithelial Survival and Resolution in a Human Model of Lung Injury
Shyamsundar, M., McAuley, D. F., Ingram, R. J., Gibson, D. S., O'Kane, D., McKeown, S. T., Edwards, A., Taggart, C., Elborn, J. S.,
Calfee, C. S., Matthay, M. A. & O'Kane, C. M. 15 Jun 2014 In : American Journal of Respiratory and Critical Care
Medicine. 189, 12, p. 1520-1529
Respiratory Infections Cause the Release of Extracellular Vesicles: Implications in Exacerbation of Asthma/COPD
Eltom, S., Dale, N., Raemdonck, K. R. G., Stevenson, C. S., Snelgrove, R. J., Sacitharan, P. K., Recchi, C., Wavre-Shapton,
S., McAuley, D. F., O'Kane, C., Belvisi, M. G. & Birrell, M. A. Jun 2014 In : PloS one. 9, 6, e101087. , e101087
miR-31 Dysregulation in Cystic Fibrosis Airways Contributes to Increased Pulmonary Cathepsin S Production
Weldon, S., McNally, P., McAuley, D. F., Oglesby, I. K., Wohlford-Lenane, C. L., Bartlett, J. A., Scott, C. J., McElvaney, N. G., Greene,
C. M., McCray, P. B. & Taggart, C. C. 15 Jul 2014 In : American Journal of Respiratory and Critical Care Medicine. 190, 2, p. 165-174
Keratinocyte Growth Factor Promotes Epithelial Survival and Resolution in a Human Model of Lung Injury
Shyamsundar, M., McAuley, D. F., Ingram, R. J., Gibson, D. S., O'Kane, D., McKeown, S. T., Edwards, A., Taggart, C., Elborn, J. S.,
Calfee, C. S., Matthay, M. A. & O'Kane, C. M. 15 Jun 2014 In : American Journal of Respiratory and Critical Care
Medicine. 189, 12, p. 1520-1529
Respiratory Syncytial Virus Infections Enhance Cigarette Smoke Induced COPD in Mice
Foronjy, R. F., Dabo, A. J., Taggart, C. C., Weldon, S. & Geraghty, P. 28 Feb 2014 In : PLoS ONE. 9, 2, e90567. , e90567
Accuracy of LightCycler® SeptiF ast for the detection and identification of pathogens in the blood of patients with suspected
sepsis: a systematic review and meta-analysis
Dark, P., Blackwood, B., Gates, S., McAuley, D., Perkins, G. D., McMullan, R., Wilson, C., Graham, D., Timms, K. & Warhurst, G. Nov
2014 In : Intensive Care Medicine. 41, 1, p. 21-33
Simvastatin in the Acute Respiratory Distress Syndrome
McAuley, D. F., Laffey, J. G., O'Kane, C. M., Perkins, G. D., Mullan, B., Trinder, T. J., Johnston, P., Hopkins, P. A., Johnston, A. J.,
McDowell, C., McNally, C. & the HARP-2 Investigators, for the Irish Critical Care Trials Group 30 Oct 2014 In : New England Journal
of Medicine. 371, p. 1695-1703
Academic medicine - revolution, evolution or extinction?
Irwin, G. W., Spence, R. A. J., McAuley, D. F., Kennedy, R. D., Gardiner, K. R. & Elborn, J. S. Sep 2014 In : The Ulster Medical
Journal. 83, 3,p. 141-5
miR-31 Dysregulation in Cystic Fibrosis Airways Contributes to Increased Pulmonary Cathepsin S Production
Weldon, S., McNally, P., McAuley, D. F., Oglesby, I. K., Wohlford-Lenane, C. L., Bartlett, J. A., Scott, C. J., McElvaney, N. G., Greene,
C. M., McCray, P. B. & Taggart, C. C. 15 Jul 2014 In : American Journal of Respiratory and Critical Care Medicine. 190, 2, p. 165-174
Keratinocyte Growth Factor Promotes Epithelial Survival and Resolution in a Human Model of Lung Injury
Shyamsundar, M., McAuley, D. F., Ingram, R. J., Gibson, D. S., O'Kane, D., McKeown, S. T., Edwards, A., Taggart, C., Elborn, J. S.,
Calfee, C. S., Matthay, M. A. & O'Kane, C. M. 15 Jun 2014 In : American Journal of Respiratory and Critical Care
Medicine. 189, 12, p. 1520-1529
Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children
Rose, L., Schultz, M. J., Cardwell, C., Jouvet, P., McAuley, D. F. & Blackwood, B. 10 Jun 2014 In : The Cochrane Library. 6
An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis
(LeoPARDS): protocol for a randomized controlled trial
L'E Orme, R. M., Perkins, G. D., McAuley, D. F., Liu, K. D., Mason, A. J., Morelli, A., Singer, M., Ashby, D. & Gordon, A. C. 02 Jun
2014 In : Trials. 15, 1, 199. , 199
The statistical significance of randomized controlled trial results is frequently fragile: a case for a Fragility Index ☆
Walsh, M., Srinathan, S. K., McAuley, D. F., Mrkobrada, M., Levine, O., Ribic, C., Molnar, A. O., Dattani, N. D., Burke, A., Guyatt, G.,
Thabane, L., Walter, S. D., Pogue, J. & Devereaux, P. J. 01 Jun 2014 In : Journal of Clinical Epidemiology. 67, 6,p. 622-628
Respiratory Infections Cause the Release of Extracellular Vesicles: Implications in Exacerbation of Asthma/COPD
Eltom, S., Dale, N., Raemdonck, K. R. G., Stevenson, C. S., Snelgrove, R. J., Sacitharan, P. K., Recchi, C., Wavre-Shapton,
S., McAuley, D. F., O'Kane, C., Belvisi, M. G. & Birrell, M. A. Jun 2014 In : PloS one. 9, 6, e101087. , e101087
Clinical grade allogeneic human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for
transplantation
McAuley, D. F., Curley, G. F., Hamid, U. I., Laffey, J. G., Abbott, J., McKenna, D. H., Fang, X., Matthay, M. A. & Lee, J. W. 01 May
2014 In :American Journal of Physiology - Lung Cellular and Molecular Physiology. 306, 9
Extracorporeal carbon dioxide removal for patients with acute respiratory failure secondary to the acute respiratory distress
syndrome: a systematic review
Fitzgerald, M., Millar, J., Blackwood, B., Davies, A., Brett, S. J., McAuley, D. F. & McNamee, J. J. May 2014 In : Critical Care. 18 , 222
Effectiveness of a programme of exercise on physical function in survivors of critical illness following discharge from the ICU: study
protocol for a randomised controlled trial (REVIVE)
O'Neill, B., McDowell, K., Bradley, J., Blackwood, B., Mullan, B., Lavery, G., Agus, A., Murphy, S., Gardiner, E. & McAuley, D. F. 27
Apr 2014 In : Trials. 15, 146. , 146
How Outcomes Are Defined in Clinical Trials of Mechanically Ventilated Adults and Children
Blackwood, B., Clarke, M., McAuley, D. F., McGuigan, P. J., Marshall, J. C. & Rose, L. 15 Apr 2014 In : American Journal of
Respiratory and Critical Care Medicine. 189, 8, p. 886-893
Statin Use and Risk of Delirium in the Critically Ill
Page, V. J., Davis, D., Zhao, X. B., Norton, S., Casarin, A., Brown, T., Ely, E. W. & McAuley, D. F. 15 Mar 2014 In : American Journal
of Respiratory and Critical Care Medicine. 189, 6, p. 666-673
The Beta Agonist Lung Injury Trial Prevention. A Randomized Controlled Trial
Perkins, G. D., Gates, S., Park, D., Gao, F., Knox, C., Holloway, B., McAuley, D. F., Ryan, J., Marzouk, J., Cooke, M. W., Lamb, S. E. &
Thickett, D. R. 15 Mar 2014 In : American Journal of Respiratory and Critical Care Medicine. 189, 6, p. 674-683
Human mesenchymal stem cells reduce the severity of acute lung injury in a sheep model of bacterial pneumonia
Asmussen, S., Ito, H., Traber, D. L., Lee, J. W., Cox, R. A., Hawkins, H. K., McAuley, D. F., McKenna, D. H., Traber, L. D., Zhuo, H.,
Wilson, J., Herndon, D. N., Prough, D. S., Liu, K. D., Matthay, M. A. & Enkhbaatar, P. 2014 In : Thorax. 69, 9, p. 819-825
Exendin-4 protects against post-myocardial infarction remodelling via specific actions on inflammation and the extracellular matrix
Robinson, E., Tate, M., McDermott, B., Green, B. D. & Grieve, D. J. Sep 2014
Endothelial NADPH Oxidase-2 Promotes Interstitial Cardiac Fibrosis and Diastolic Dysfunction Through Proinflammatory Effects
and Endothelial-Mesenchymal Transition
Murdoch, C. E., Chaubey, S., Zeng, L., Yu, B., Ivetic, A., Walker, S. J., Vanhoutte, D., Heymans, S., Grieve, D. J., Cave, A. C., Brewer,
A. C., Zhang, M. & Shah, A. M. Jun 2014 In : Journal of the American College of Cardiology. 63, 24, p. 2734-2741
Precise activation of EC-regulatory-networks underpinning direct reprogramming of vascular endothelial cells for use in
regenerative medicine
Kelaini, S., Cochrane, A., Grieve, D., Stitt, A. & Margariti, A. Jun 2014
Adult cardiac fibroblast proliferation is modulated by calcium/calmodulin-dependent protein kinase II in normal and
hypertrophied hearts
Martin, T. P., Lawan, A., Robinson, E., Grieve, D. J., Plevin, R., Paul, A. & Currie, S. Feb 2014 In : Pflügers Archiv - European Journal
of Physiology. 466, 2, p. 319-330
Efficient Drug Delivery and Induction of Apoptosis in Colorectal Tumors Using a Death Receptor 5-Targeted Nanomedicine
Schmid, D., Fay, F., Small, D. M., Jaworski, J., Riley, J. S., Tegazzini, D., Fenning, C., Jones, D. S., Johnston, P. G., Longley, D.
B. & Scott, C. J. Dec 2014 In : Molecular therapy : the journal of the American Society of Gene Therapy. 22, 12, p. 2083-2092
Gastroretentive Extended-Release Floating Granules Prepared Using a Novel Fluidized Hot Melt Granulation (FHMG) Technique
Zhai, H., Jones, D. S., McCoy, C. P., Madi, A. M., Tian, Y. & Andrews, G. P. Oct 2014 In : Molecular Pharmaceutics. 11, 10, p. 34713483
Photodynamic Antimicrobial Polymers for Infection Control
McCoy, C. P., O'Neil, E. J., Cowley, J. F., Carson, L., De Baróid, A. T., Gdowski, G. T., Gorman, S. P. & Jones, D. S. 24 Sep 2014 In
: PloS one. 9, 9, e108500. , e108500
Ultrashort Cationic Naphthalene-Derived Self-Assembled Peptides as Antimicrobial Nanomaterials
Laverty, G., McCloskey, A. P., Gilmore, B. F., Jones, D. S., Zhou, J. & Xu, B. 08 Sep 2014 In : Biomacromolecules. 15, 9, p. 3429 −
3439
Antibacterial hydrogel could influence development of medical implants
Laverty, G., McCloskey, A., Gilmore, B., Jones, D., Zhou, J. & Xu, B. 08 Sep 2014
Self-Disinfecting Urinary Biomaterials: pH-Triggered Quinolone Release for Prevention of Catheter-Associated Urinary Tract
Infections
McCoy, C. P., Irwin, N. J., Brady, C., Carson, L., Jones, D. S. & Gorman, S. P. 31 Aug 2014
Using Debate to Teach Pharmacy Students About Ethical Issues
Hanna, L-A., Barry, J., Donnelly, R., Hughes, F., Jones, D., Laverty, G., Parsons, C. & Ryan, C. 17 Apr 2014 In : American Journal of
Pharmaceutical Education. 78, 3, p. 1-8 57. , 57
Microneedle-mediated intrascleral delivery of in situ forming thermoresponsive implants for sustained ocular drug delivery.
Thakur, R. & Jones, D. Apr 2014 In : Investigative Opthalmology and Visual Science. 55, p. 5263
Solvent induced phase inversion-based in situ forming controlled release drug delivery implants
Thakur, R. R. S., McMillan, H. L. & Jones, D. S. 28 Feb 2014 In : Journal of Controlled Release. 176, p. 8-23
Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis.
Linehan, E., Dombrowski, Y., Snoddy, R., Fallon, P. G., Kissenpfennig, A. & Fitzgerald, D. C. Aug 2014 In : Aging cell. p. 699-708
Interferon regulatory factor (IRF) 3 is critical for the development of experimental autoimmune encephalomyelitis.
Fitzgerald, D., O'Brien, K., Young, A., Fonseca-Kelly, Z., Rostami, A. & Gran, B. 28 Jul 2014 In : Journal of
Neuroinflammation. 11, 130
Bone morphogenetic proteins and their antagonists: current and emerging clinical uses
Ali, I. H. A. & Brazil, D. P. Aug 2014 In : British Journal of Pharmacology. 171, 15, p. 3620-3632
β-Lapachone alleviates alcoholic fatty liver disease in rats
Shin, S., Park, J., Li, Y., Nam Min, K., Kong, G., Min Hur, G., Man Kim, J., Shong, M., Jung, M-S., Kook Park, J., Jeong, K-H., Gyu Park,
M., Hwan Kwak, T. & Brazil, D. Feb 2014 In : Cellular Signalling. 26, 2, p. 295-305
The Host Defence Peptide LL-37 is Susceptible to Proteolytic Degradation by Wound Fluid Isolated from Foot Ulcers of Diabetic
Patients
McCrudden, M. T. C., McLean, D. T. F., Zhou, M., Shaw, J., Linden, G. J., Irwin, C. R. & Lundy, F. T. Dec 2014 In : International
Journal of Peptide Research and Therapeutics. 20, 4, p. 457-464
Antimicrobial and immunomodulatory properties of PGLa-AM1, CPF-AM1, and magainin-AM1: Potent activity against oral
pathogens
McLean, D. T. F., McCrudden, M. T. C., Linden, G. J., Irwin, C. R., Conlon, J. M. & Lundy, F. T. Nov 2014 In : Regulatory
Peptides. 194-195, p. 63-68
Experimental autoimmune uveoretinitis (EAU)-related tissue damage and angiogenesis is reduced in CCL2⁻/⁻CX₃CR1gfp/gfp mice.
Zhao, J., Chen, M. & Xu, H. Nov 2014 In : Investigative ophthalmology & visual science. 55, 11, p. 7572-7582
IL-33 attenuates the development of experimental autoimmune uveitis
Barbour, M., Allan, D., Xu, H., Pei, C., Chen, M., Niedbala, W., Fukada, S. Y., Besnard, A-G., Alves-Filho, J. C., Tong, X., Forrester, J.
V., Liew, F. Y. & Jiang, H-R. Nov 2014 In : European Journal of Immunology. 44, 11, p. 3320-3329
Pathophysiology and Pathogenesis of Diabetic Retinopathy
Xu, H., Curtis, T. & Stitt, A. Aug 2014 Diapedia, The Living Textbook of Diabetes [internet].
Phytocannabinoids in Degenerative and Inflammatory Retinal Diseases: Glaucoma, Age-Related Macular Degeneration, Diabetic
Retinopathy and Uveoretinitis
Xu, H. & Azuara-Blanco, A. Aug 2014 Handbook of Cannabis. Pertwee, R. (ed.). Oxford University Press, p. 601-618
Regulating macrophage phenotype and function by retinal pigment epithelial cells
Chen, M., Zhao, J. & Xu, H. 24 Jul 2014
Culture and Characterization of Microglia from the Adult Murine Retina
Devarajan, G., Chen, M., Muckersie, E. & Xu, H. 29 May 2014 In : The Scientific World Journal. 2014, 894368. , 894368
Loss of Synaptic Connectivity, Particularly in Second Order Neurons Is a Key Feature of Diabetic Retinal Neuropathy in the
Ins2Akita Mouse
Hombrebueno, J. R., Chen, M., Penalva, R. G. & Xu, H. 21 May 2014 In : PloS one. 9, 5, e97970. , e97970
The role of WNT singling activation and its blockage in the focal retinal lesion of Ccl2-/-/Cx3cr1-/- mice with and without rd8
background
Tuo, J., Wang, Y., Cheng, R., Li, Y., Chen, M., Qian, H., Abu-Asab, M., Xu, H., Ma, J. & Chan, C-C. May 2014
Intravitreal Injection of Normal Saline Induces Retinal Degeneration in the C57BL/6J Mouse
Hombrebueno, J. R., Luo, C., Guo, L., Chen, M. & Xu, H. Mar 2014 In : Translational Vision Science & Technology. 3, 2, 3. , 3
RAGE Regulates Immune Cell Infiltration and Angiogenesis in Choroidal Neovascularization
Chen, M., Glenn, J. V., Dasari, S., McVicar, C., Ward, M., Colhoun, L., Quinn, M., Bierhaus, A., Xu, H. & Stitt, A. W. 26 Feb 2014 In
: PloS one. 9, 2, e89548. , e89548
Optical coherence tomography for the diagnosis of neovascular age-related macular degeneration: a systematic review
Castillo, M. M., Mowatt, G., Lois, N., Elders, A., Fraser, C., Amoaku, W., Burr, J. M., Lotery, A. J., Ramsay, C. R. & Azuara-Blanco,
A. Dec 2014 In : Eye. 28
Optical coherence tomography for the diagnosis, monitoring and guiding of treatment for neovascular age-related macular
degeneration: a systematic review and economic evaluation
Mowatt, G., Hernández, R., Castillo, M., Lois, N., Elders, A., Fraser, C., Aremu, O., Amoaku, W., Burr, J., Lotery, A., Ramsay, C.
& Azuara-Blanco, A. Nov 2014 In : Health Technology Assessment. 18, 69, p. 1-254
Drug treatment of macular oedema secondary to central retinal vein occlusion: a network meta-analysis
Ford, J. A., Shyangdan, D., Uthman, O. A., Lois, N. & Waugh, N. 23 Jul 2014 In : BMJ Open. 4, 7, p. e005292
Fundus autofluorescence in patients with retinal pigment epithelial (RPE) tears: an in-vivo evaluation of RPE resurfacing
Mendis, R. & Lois, N. Jul 2014 In : Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur
klinische und experimentelle Ophthalmologie. 252, 7, p. 1059-1063
Endothelial progenitor cells in diabetic retinopathy
Lois, N., McCarter, R. V., O'Neill, C., Medina, R. J. & Stitt, A. W. Apr 2014 In : Frontiers in endocrinology. 5, 44. , 44
Treatments for macular oedema following central retinal vein occlusion: systematic review
Ford, J. A., Clar, C., Lois, N., Barton, S., Thomas, S., Court, R., Shyangdan, D. & Waugh, N. 10 Feb 2014 In : BMJ
Open. 4,2, e004120. , e004120
Keratinocyte Growth Factor Promotes Epithelial Survival and Resolution in a Human Model of Lung Injury
Shyamsundar, M., McAuley, D. F., Ingram, R. J., Gibson, D. S., O'Kane, D., McKeown, S. T., Edwards, A., Taggart, C., Elborn, J. S.,
Calfee, C. S., Matthay, M. A. & O'Kane, C. M. 15 Jun 2014 In : American Journal of Respiratory and Critical Care
Medicine. 189, 12, p. 1520-1529
Anthrax Lethal Factor as an Immune Target in Humans and Transgenic Mice and the Impact of HLA Polymorphism on CD4+ T Cell
Immunity
Ascough, S., Ingram, R. J., Chu, K. K., Reynolds, C. J., Musson, J. A., Doganay, M., Metan, G., Ozkul, Y., Baillie, L., Sriskandan, S.,
Moore, S. J., Gallagher, T. B., Dyson, H., Williamson, E. D., Robinson, J. H., Maillere, B., Boyton, R. J. & Altmann, D. M. May 2014 In
: PLoS Pathogens. 10, 5, e1004085. , e1004085
Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony–forming cells
O'Neill, C. L. , Medina, R. J. , Stitt, A. W. & 21 others Nov 2014 In : Nature Biotechnology. 32, 11, p. 1151-1157
Endothelial progenitor cells in diabetic retinopathy
Lois, N., McCarter, R. V., O'Neill, C., Medina, R. J. & Stitt, A. W. Apr 2014 In : Frontiers in endocrinology. 5, 44. , 44
S21 Culture Independent Identification Of Bacterial Communities In The Respiratory Tract Of Patients With Copd, Healthy Nonsmokers And Healthy Smokers
Einarsson, G. G., Walker, A., Tunney, M. M. & Elborn, J. S. 03 Dec 2014 p. A13-A14
Pooled analysis of tiotropium Respimat® pharmacokinetics in cystic fibrosis
Sharma, A., Geller, D. E., Moroni-Zentgraf, P., Kattenbeck, S., Schmid, M., Boland, K., Rapp, B., Konstan, M. W., Ratjen, F., Elborn, J.
S. & Koker, P. Dec 2014 In : Pulmonary Pharmacology and Therapeutics. 29, 2, p. 217-223
S22 The Effect Of Cigarette Smoke On Important Pathogens In Copd Lung Infection
McGown, K., Tunney, M. M., McGrath, S. J., Elborn, J. S. & Gilpin, D. F. Dec 2014 In : Thorax. 69, Supplement 2, p. A14
Targeting trypsin-like proteases in cystic fibrosis airways
Reihill, J., Walker, B., Elborn, J. & Martin, L. 23 Oct 2014
Long-term macrolide maintenance therapy in non-CF bronchiectasis: Evidence and questions
Haworth, C. S., Bilton, D. & Elborn, J. S. Oct 2014 In : Respiratory Medicine. 108, 10, p. 1397-1408
Mechanisms of reduced susceptibility and genotypic prediction of antibiotic resistance in Prevotella isolated from cystic fibrosis
(CF) and non-CF patients
Sherrard, L. J., Schaible, B., Graham, K. A., McGrath, S. J., McIlreavey, L., Hatch, J., Wolfgang, M. C., Muhlebach, M. S., Gilpin, D. F.,
Schneiders, T., Elborn, J. S. & Tunney, M. M. Oct 2014 In : Journal of Antimicrobial Chemotherapy. 69, 10, p. 2690-8
The effect of cigarette smoke on key pathogens in COPD lung infection
McGown, K-A., McGrath, S., Tunney, M., Elborn, S. & Gilpin, D. 01 Sep 2014 In : European Respiratory Journal. 44, Supplement
58, p. P4942
Academic medicine - revolution, evolution or extinction?
Irwin, G. W., Spence, R. A. J., McAuley, D. F., Kennedy, R. D., Gardiner, K. R. & Elborn, J. S. Sep 2014 In : The Ulster Medical
Journal. 83, 3,p. 141-5
Antibiotic Management of Lung Infections in Cystic Fibrosis. I. The Microbiome, Methicillin-Resistant Staphylococcus aureus,
Gram-Negative Bacteria, and Multiple Infections
Chmiel, J. F., Aksamit, T. R., Chotirmall, S. H., Dasenbrook, E. C., Elborn, J. S., LiPuma, J. J., Ranganathan, S. C., Waters, V. J. &
Ratjen, F. A. Sep 2014 In : Annals of the American Thoracic Society. 11, 7, p. 1120-1129
Characterization of extended-spectrum β-Lactamase production by prevotella species from cystic fibrosis patients and detection
of tem-type genes
Sherrard, L., Matier, T., Gilpin, D., Muhlebach, M. S., Elborn, J. & Tunney, M. M. Sep 2014 In : Pediatric Pulmonology. 49, S38, p.
328
Medical consensus, guidelines, and position papers: A policy for the ECFS
De Boeck, K., Castellani, C. & Elborn, J. S. Sep 2014 In : Journal of Cystic Fibrosis. 13, 5, p. 495-498
Antimicrobial resistance in the respiratory microbiota of people with cystic fibrosis
Sherrard, L. J., Tunney, M. M. & Elborn, J. S. 23 Aug 2014 In : The Lancet. 384, 9944, p. 703-713
Treatment adherence and health outcomes in patients with bronchiectasis
McCullough, A. R., Tunney, M. M., Quittner, A. L., Elborn, J. S., Bradley, J. M. & Hughes, C. M. 01 Jul 2014 In : BMC Pulmonary
Medicine. 14, 107. , 107
Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial
Elborn, J. S. & 25 others Jul 2014 In : The Lancet Respiratory Medicine. 2, 7, p. 539-547
SMAD inhibition attenuates epithelial to mesenchymal transition by primary keratinocytes in vitro
O'Kane, D., Jackson, M. V., Kissenpfennig, A., Spence, S., Damkat-Thomas, L., Tolland, J. P., Smyth, A. E., Denton, C. P., Elborn, J. S.,
McAuley, D. F. & O'Kane, C. M. Jul 2014 In : Experimental dermatology. 23, 7, p. 497-503
Keratinocyte Growth Factor Promotes Epithelial Survival and Resolution in a Human Model of Lung Injury
Shyamsundar, M., McAuley, D. F., Ingram, R. J., Gibson, D. S., O'Kane, D., McKeown, S. T., Edwards, A., Taggart, C., Elborn, J. S.,
Calfee, C. S., Matthay, M. A. & O'Kane, C. M. 15 Jun 2014 In : American Journal of Respiratory and Critical Care
Medicine. 189, 12, p. 1520-1529
69 Rapid induction of high level azithromycin resistance in clinical CF isolates
McGettigan, C., Kenny, C., Sherrard, L., McCaughey, G., McGrath, S. J., McIlreavey, L., Elborn, J. S. & Tunney, M. Jun 2014 In
: Journal of Cystic Fibrosis. 13, Supplement 2, p. S64
70 Expression of RND-type efflux pumps as a mechanism of antibiotic resistance in clinical Prevotella isolates
Sherrard, L., Schaible, B., Gilpin, D. F., Elborn, J. S. & Tunney, M. Jun 2014 In : Journal of Cystic Fibrosis. 13, Supplement 2, p. S64
71 Extended-spectrum β-lactamase (ESβL) production: a mechanism of resistance to ceftazidime in Prevotella species isolated
from patients with CF
Sherrard, L., Matier, T., Gilpin, D. F., Muhlebach, M., Elborn, J. S., Schneiders, T. & Tunney, M. Jun 2014 In : Journal of Cystic
Fibrosis. 13,Supplement 2, p. S64
WS16.6 MALDI-TOF as an alternative method for the identification and typing of Prevotella species from CF patients
McIlreavey, L., Graham, K., McLean, D., McGrath, S. J., Bull, M., Mahenthiralingam, E., Elborn, J. S., Tunney, M., Rolain, J-M.
& Gilpin, D. F.Jun 2014 In : Journal of Cystic Fibrosis. 13, p. S34
WS19.3 Virulence of serial Pseudomonas aeruginosa isolates grown under aerobic and anaerobic conditions using the Galleria
mellonella infection model
Vallieres, E., Sherrard, L., McLean, D., Downey, D. G., Tunney, M. & Elborn, J. S. Jun 2014 In : Journal of Cystic
Fibrosis. 13, Supplement 2, p. S37
WS2.9 Inflammatory potential and antimicrobial susceptibility of bacteria in the cultivatable CF lung microbiome
Hatch, J., Kim, J. D., McGrath, S. J., McIlreavey, L., Gilpin, D. F., Lavelle, G. M., Murray, M., Boucher, R. C., Elborn, J. S., McElvaney,
N. G., Muhlebach, M., Tunney, M., Wolfgang, M. C. & Randell, S. H. Jun 2014 In : Journal of Cystic Fibrosis. 13, Supplement 2, p. S5
European Cystic Fibrosis Society Standards of Care: Quality Management in cystic fibrosis
Stern, M., Bertrand, D. P., Bignamini, E., Corey, M., Dembski, B., Goss, C. H., Pressler, T., Rault, G., Viviani, L., Elborn, J. S. &
Castellani, C.May 2014 In : Journal of Cystic Fibrosis. 13, Supplement 1, p. S43-S59
Interventions for enhancing adherence to treatment in adults with bronchiectasis
McCullough, A., Ryan, C., Bradley, J. M., O'Neill, B., Elborn, S. & Hughes, C. 19 Mar 2014 In : Cochrane database of systematic
reviews (Online). 2014, 3,
Bronchiectasis Severity: Time to Score
Restrepo, M. & Elborn, J. S. 01 Mar 2014 In : American Journal of Respiratory and Critical Care Medicine. 189, 5, p. 508-509
Inflammatory and cytotoxic effects of acrolein, nicotine, acetylaldehyde and cigarette smoke extract on human nasal epithelial
cells
Comer, D. M., Elborn, J. S. & Ennis, M. 01 Mar 2014 In : BMC Pulmonary Medicine. 14, 32. , 32
BIIL 284 reduces neutrophil numbers but increases P. aeruginosa bacteremia and inflammation in mouse lungs
Döring, G., Bragonzi, A., Paroni, M., Aktürk, F-F., Cigana, C., Schmidt, A., Gilpin, D., Heyder, S., Born, T., Smaczny, C., Kohlhäufl, M.,
Wagner, T. O. F., Loebinger, M. R., Bilton, D., Tunney, M. M., Elborn, J. S., Pier, G. B., Konstan, M. W. & Ulrich, M. Mar 2014 In
: Journal of Cystic Fibrosis. 13, 2, p. 156-63
Inflammatory and immunological biomarkers are not related to survival in adults with Cystic Fibrosis
Moffitt, K. L., Martin, S. L., Jones, A. M., Webb, A. K., Cardwell, C., Tunney, M. M. & Elborn, J. S. Jan 2014 In : Journal of Cystic
Fibrosis. 13, 1,p. 63-68
Practical Guidelines: Lung Transplantation in Patients with Cystic Fibrosis
Hirche, T. O., Knoop, C., Hebestreit, H., Shimmin, D., Solé, A., Elborn, J. S., Ellemunter, H., Aurora, P., Hogardt, M., Wagner, T. O. F.
& Ecorn-Cf Study Group, S. G. 2014 In : Pulmonary Medicine. 2014, 621342. , 621342
Isotretinoin therapy changes the expression of antimicrobial peptides in acne vulgaris
Borovaya, A., Dombrowski, Y., Zwicker, S., Olisova, O., Ruzicka, T., Wolf, R., Schauber, J. & Sárdy, M. Oct 2014 In : Archives of
Dermatological Research. 306, 8, p. 689-700
Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis.
Linehan, E., Dombrowski, Y., Snoddy, R., Fallon, P. G., Kissenpfennig, A. & Fitzgerald, D. C. Aug 2014 In : Aging cell. p. 699-708
Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferonγ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment
Tillack, C., Ehmann, L. M., Friedrich, M., Laubender, R. P., Papay, P., Vogelsang, H., Stallhofer, J., Beigel, F., Bedynek, A., Wetzke,
M., Maier, H., Koburger, M., Wagner, J., Glas, J., Diegelmann, J., Koglin, S., Dombrowski, Y., Schauber, J., Wollenberg, A. & Brand,
S. Apr 2014 In : Gut.63, 4, p. 567-577
Narrow-band Ultraviolet B Treatment Boosts Serum 25-hydroxyvitamin D in Patients with Psoriasis on Oral Vitamin D
Supplementation
Ala-Houhala, M. J., Karppinen, T., Vähävihu, K., Kautiainen, H., Dombrowski, Y., Snellman, E., Schauber, J. & Reunala, T.Mar
2014 In : Acta Dermato-Venereologica . 94, 2, p. 146-151
Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung injury.
Shyamsundar M, McAuley DF, Ingram RJ, Gibson DS, O'Kane D, McKeown ST, Edwards A, Taggart C, Elborn JS, Calfee CS, Matthay
MA, O'Kane CM.
Am J Respir Crit Care Med. 2014 Jun 15;189(12):1520-9. doi: 10.1164/rccm.201310-1892OC.
Reply to Letter: "Effect of Simvastatin on Physiological and Biological Outcomes in Patients Undergoing Esophagectomy: A
Randomized Placebo-Controlled Trial"
Shyamsundar M, McAuley DF, Oʼkane CM.
Ann Surg. 2014 Apr 16.
Effect of simvastatin on physiological and biological outcomes in patients undergoing esophagectomy: a randomized placebocontrolled trial.
Shyamsundar M, McAuley DF, Shields MO, MacSweeney R, Duffy MJ, Johnston JR, McGuigan J, Backman JT, Calfee CS, Matthay
MM, Griffiths MJ, McDowell C, Elborn SJ, OʼKane CM.
Ann Surg. 2014 Jan;259(1):26-31.