GBD PROFILE: JORDAN GLOBAL BURDEN OF DISEASES, INJURIES, AND RISK FACTORS STUDY 2010 The Global Burden of Disease Study 2010 (GBD 2010) is a collaborative project of nearly 500 researchers in 50 countries led by the Institute for Health Metrics and Evaluation (IHME) at the University of Washington. It is the largest systematic scientific effort in history to quantify levels and trends of health loss due to diseases, injuries, and risk factors. GBD serves as a global public good to inform evidence-based policymaking and health systems design. PROFILE OVERVIEW 15 + −7 9 80 −7 4 75 −6 9 70 −6 4 65 −5 9 60 −5 4 55 −4 9 50 −4 4 45 −3 9 40 −3 4 35 −2 9 30 −2 4 25 −1 9 20 15 9 0 −1 4 ● This chart shows the decline in mortality rate at every age range. The higher points on the chart indicate that declines in mortality rates were faster in those age groups between 1990 and 2010. The greatest reductions in all-cause mortality rate were experienced by males aged <1 year (58%). Females aged 80+ years saw the smallest decrease in mortality rate (6%). 30 10 ● 45 4 ALL-CAUSE MORTALITY RATE 60 5− ● Percent decline in age-specific mortality rate by sex from 1990-2010 in Jordan 1− ● In terms of the number of years of life lost (YLLs) due to premature death in Jordan, ischemic heart disease, congenital anomalies, and cerebrovascular disease were the highest ranking causes in 2010. Of the 25 most important causes of burden, as measured by disability-adjusted life years (DALYs), lower respiratory infections showed the largest decrease, falling by 50% from 1990 to 2010. The leading risk factor in Jordan is high body-mass index. Percent decline in age−specific mortality rate ● Age group Males Females CAUSES OF PREMATURE DEATH Years of life lost (YLLs) quantify premature mortality by weighting younger deaths more than older deaths. Ranks for top 25 causes of YLLs 1990-2010, Jordan # YLLs in thousands (% of total) Rank and disorder 1990 91 (13.7%) 1 Congenital anomalies 68 (10.2%) 2 Preterm birth complications 65 (9.7%) 3 Ischemic heart disease 52 (7.8%) 4 Lower respiratory infections 39 (5.8%) 5 Stroke 31 (4.7%) 6 Road injury 16 (2.4%) 7 Neonatal encephalopathy 13 (1.9%) 8 COPD 14 (2.1%) 9 Neonatal sepsis 11 (1.7%) 10 Hypertensive heart disease 10 (1.6%) 11 Other cardio & circulatory 11 (1.6%) 12 Diarrheal diseases 9 (1.3%) 13 Diabetes 8 (1.3%) 14 Mechanical forces 8 (1.2%) 15 Maternal disorders 8 (1.2%) 16 Fire 8 (1.2%) 17 Chronic kidney disease 8 (1.1%) 18 Drowning 7 (1.1%) 19 Interpersonal violence 7 (1.0%) 20 Leukemia 7 (1.0%) 21 Asthma 6 (0.9%) 22 Meningitis 6 (0.9%) 23 Cirrhosis 6 (0.9%) 24 Falls 6 (0.9%) 25 Lung cancer 26 Brain cancer 29 Breast cancer 30 Colorectal cancer 31 Self-harm http://www.healthmetricsandevaluation.org Rank and disorder 2010 1 Ischemic heart disease 2 Congenital anomalies 3 Stroke 4 Preterm birth complications 5 Road injury 6 Diabetes 7 Lower respiratory infections 8 Interpersonal violence 9 Chronic kidney disease 10 Hypertensive heart disease 11 Breast cancer 12 Other cardio & circulatory 13 Leukemia 14 Cirrhosis 15 Lung cancer 16 Neonatal encephalopathy 17 Neonatal sepsis 18 Fire 19 Brain cancer 20 Colorectal cancer 21 Falls 22 COPD 23 Drowning 24 Mechanical forces 25 Self-harm 27 Maternal disorders 29 Meningitis 31 Diarrheal diseases 38 Asthma # YLLs in thousands (% of total) % change 72 (10.9%) 12 71 (10.7%) -21 42 (6.3%) 8 39 (5.9%) -41 37 (5.6%) 16 29 (4.3%) 252 25 (3.8%) -51 22 (3.3%) 238 19 (2.9%) 150 16 (2.5%) 45 13 (2.0%) 291 11 (1.7%) 8 11 (1.7%) 60 9 (1.4%) 60 9 (1.4%) 57 10 (1.4%) -40 9 (1.4%) -30 9 (1.3%) 8 8 (1.3%) 75 8 (1.2%) 130 8 (1.2%) 35 8 (1.2%) -38 7 (1.0%) -10 6 (0.9%) -27 5 (0.8%) 69 This chart shows the change in the top 25 causes of YLLs due to premature mortality from 1990 to 2010. Solid lines indicate a cause has moved up in rank or stayed the same. Broken lines indicate a cause has moved down in rank. The causes are color coded by blue for non-communicable diseases, green for injuries, and red for communicable, maternal, neonatal, and nutritional causes of death. Jordan | GBD | page 1 YEARS LIVED WITH DISABILITY (YLDs) Years lived with disability (YLDs) are estimated by weighting the prevalence of different conditions based on severity. The top five leading causes of YLDs in Jordan are major depressive disorder, low back pain, iron-deficiency anemia, diabetes mellitus, and anxiety disorders. Jordan YLDs by cause and age 2010 60,000 War & disaster Intentional injuries Unintentional injuries Transport injuries Other non−communicable Musculoskeletal disorders Diabetes/urogen/blood/endo 40,000 Mental & behavioral disorders Neurological disorders Digestive diseases YLDs The size of the colored portion in each bar represents the number of YLDs attributable to each cause. The height of each bar shows which age groups had the most YLDs in 2010. The causes are aggregated. For example, musculoskeletal disorders include low back pain and neck pain. Cirrhosis Chronic respiratory diseases Cardio & circulatory diseases Cancer Other communicable 20,000 Nutritional deficiencies Neonatal disorders Maternal disorders NTD & malaria Diarrhea/LRI/other infectious HIV/AIDS & tuberculosis 0− 6 7− da 28 27 ys −3 da 64 ys 1− da 4 ys 5− yea 10 9 y rs −1 ea 15 4 y rs −1 ea 20 9 y rs −2 ea 25 4 y rs −2 ea 30 9 y rs −3 ea 35 4 y rs −3 ea 40 9 y rs −4 ea 45 4 y rs −4 ea 50 9 y rs −5 ea 55 4 y rs −5 ea 60 9 y rs −6 ea 65 4 y rs −6 ea 70 9 y rs −7 ea 75 4 y rs −7 ea 9 rs 80 yea + rs ye ar s 0 DISABILITY-ADJUSTED LIFE YEARS (DALYs) Disability-adjusted life years (DALYs) quantify both premature mortality (YLLs) and disability (YLDs) within a population. In Jordan, the top three causes of DALYs in 2010 were major depressive disorder, ischemic heart disease, and congenital anomalies. The only cause to appear in the 10 leading causes of DALYs in 2010 and not 1990 was diabetes mellitus. 21 OTHER CARDIO & CIRCULATORY BREAST CANCER 19 MIGRAINE DRUG USE DISORDERS 18 HYPERTENSIVE HEART DISEASE OTHER MUSCULOSKELETAL NECK PAIN 16 FALLS CHRONIC KIDNEY DISEASE INTERPERSONAL VIOLENCE COPD ANXIETY DISORDERS 15 10 24 11 12 13 14 17 20 22 23 25 DIARRHEAL DISEASES 9 NEONATAL ENCEPHALOPATHY 8 PRETERM BIRTH COMPLICATIONS 4 CONGENITAL ANOMALIES -50 0 7 ASTHMA 6 IRON-DEFICIENCY ANEMIA 5 STROKE ROAD INJURY DIABETES LOW BACK PAIN MAJOR DEPRESSIVE DISORDER ISCHEMIC HEART DISEASE 150 100 50 2 LOWER RESPIRATORY INFECTIONS CC Non-communicable -150 CC Communicable, maternal, neonatal, and nutritional 1 3 -100 Percent change 1990-2010 The top 25 causes of DALYs are ranked from left to right in order of the number of DALYs they contributed in 2010. Bars going up show the percent by which DALYs have increased since 1990. Bars going down show the percent by which DALYs have decreased. Globally, non-communicable diseases and injuries are generally on the rise, while communicable, maternal, neonatal, and nutritional causes of DALYs are generally on the decline. 200 Leading causes of DALYs and percent change 1990 to 2010 for Jordan -200 CC Injuries http://www.healthmetricsandevaluation.org Jordan | GBD | page 2 RISK FACTORS Overall, the three risk factors that account for the most disease burden in Jordan are high body-mass index, dietary risks, and high fasting plasma glucose. The leading risk factors for children under 5 and adults aged 15-49 years were suboptimal breastfeeding and dietary risks, respectively, in 2010. Burden of disease attributable to 15 leading risk factors in 2010, expressed as a percentage of Jordan DALYs High body−mass index Dietary risks War & disaster High fasting plasma glucose The graph shows the top 15 risk factors for Jordan. The colored portion of each bar represents the specific diseases attributable to that risk factor while bar size represents the percentage of DALYs linked to specific risk factors. Intentional injuries Unintentional injuries High blood pressure Transport injuries Other non−communicable Smoking Musculoskeletal disorders Diabetes/urogen/blood/endo Physical inactivity Mental & behavioral disorders Neurological disorders Iron deficiency Digestive diseases Ambient PM pollution Cirrhosis Chronic respiratory diseases High total cholesterol Cardio & circulatory diseases Cancer Occupational risks Other communicable Nutritional deficiencies Drug use Neonatal disorders Maternal disorders Intimate partner violence NTD & malaria Diarrhea/LRI/other infectious Alcohol use HIV/AIDS & tuberculosis Suboptimal breastfeeding Childhood sexual abuse 0 1 2 3 4 5 6 7 8 % DALYs attributable to risk factors 9 10 11 COUNTRY BENCHMARKING OF BURDEN OF DISEASE Understanding the relative performance of Jordan against other comparator countries provides key insight into public health successes and areas where Jordan might be falling behind. The table identifies Jordan's rank across 14 other comparator countries, selected and ordered by income per capita, for five metrics of interest, with 1 indicating the best rank and 15 indicating the worst rank. ● Age-standardized rates are used to make meaningful comparisons across time by adjusting for changes in population size and age structure. ● Life expectancy incorporates mortality, and health-adjusted life expectancy further incorporates years lived in less than ideal health. ● In 2010, Jordan ranked 4th for age-standardized death rate and 11th for age-standardized YLD rate. Country Age-standardized death rates, YLL rates, YLD rates, and life expectancy at birth and health-adjusted life expectancy at birth for 1990 and 2010, both sexes combined Age-standardized death rate Age-standardized YLL rate Age-standardized YLD rate Health-adjusted life Life expectancy at birth (per 100,000) (per 100,000) (per 100,000) expectancy at birth 1990 2010 1990 2010 1990 2010 1990 2010 1990 2010 Rate Rank Rate Rank Rate Rank Rate Rank Rate Rank Rate Rank LE Rank LE Rank HALE Rank HALE Rank 1,144 10 919 10 39,780 12 24,522 10 11,911 4 11,933 7 62.8 11 69.3 10 54.4 10 60 9 896 5 607 3 24,989 5 14,024 3 9,639 1 8,782 1 69.3 5 75.7 3 61.7 1 67.8 2 Namibia 1,259 13 1,298 14 39,681 11 42,112 13 13,774 13 13,809 14 62.4 12 61.6 13 53.2 12 52.5 13 Samoa 1,088 9 863 9 28,245 6 21,441 7 12,397 5 11,587 4 67.2 6 70.8 7 58 6 61.5 7 Egypt 1,065 8 844 8 35,058 9 22,148 8 12,868 8 11,979 8 64.6 9 70.6 8 53.6 11 59.1 10 Guatemala 8 Turkmenistan China 1,061 7 787 7 36,242 10 24,337 9 12,800 7 11,705 6 64.5 10 70.5 9 55.3 9 61 Armenia 809 3 674 5 24,125 3 17,197 5 11,778 3 11,588 5 70.3 3 73.9 5 60.6 4 63.7 5 Jordan 792 1 619 4 21,127 1 14,448 4 12,452 6 12,527 11 71.5 1 75.4 4 60.9 2 64 4 Vanuatu 1,507 14 1,291 13 41,590 14 34,595 12 13,346 12 12,657 12 61.6 14 64.3 12 53 14 55.7 12 Maldives 997 6 440 1 34,466 8 11,060 1 13,138 10 11,281 3 65.1 8 78.8 1 55.7 8 68 1 1,995 15 1,257 12 82,686 15 44,380 14 15,039 15 13,712 13 47.4 15 60.7 14 40.2 15 51.7 14 Angola Swaziland 1,239 12 2,186 15 39,973 13 80,065 15 13,819 14 15,781 15 62.3 13 49.4 15 53 13 41.8 15 Fiji 1,184 11 1,068 11 32,309 7 28,494 11 13,180 11 12,351 10 65.4 7 67.2 11 56 7 58 11 Georgia 825 4 716 6 24,291 4 19,529 6 11,437 2 11,256 2 70.1 4 72.6 6 60.8 3 63 6 Syria 797 2 513 2 21,457 2 12,094 2 13,133 9 12,031 9 71.4 2 77.6 2 60.3 5 66 3 http://www.healthmetricsandevaluation.org Jordan | GBD | page 3 COUNTRY BENCHMARKING OF BURDEN OF DISEASE, CONTINUED This figure shows the rank of Jordan relative to the same comparator countries for the leading causes of DALYs in 1990 (top) and 2010 (bottom). ● The columns are ordered by the absolute number of DALYs in Jordan for that particular year, with greatest burden on the left. ● The numbers indicate the rank across countries for each cause in terms of age-standardized DALY rates, with 1 as the best performance and 15 as the worst. Asthma Neonatal encephalopathy Diarrheal diseases Falls Neonatal sepsis Other cardio & circulatory Chronic kidney disease Mechanical forces Fire Maternal disorders Other musculoskeletal 14 5 11 7 8 5 5 14 10 8 3 4 10 9 10 4 9 9 4 8 10 6 1 4 1 15 1 1 11 3 10 1 2 6 1 8 3 3 1 3 3 Namibia Samoa 7 1 11 1 5 6 9 4 9 11 3 8 11 2 3 10 12 2 13 9 11 15 10 14 10 3 13 6 2 14 12 11 13 7 15 1 12 5 14 7 6 13 14 1 10 12 14 7 7 15 Egypt 11 14 9 12 8 9 9 15 11 10 8 6 1 12 6 7 14 13 8 2 15 5 4 9 1 Guatemala Armenia 4 15 3 13 1 2 12 12 14 2 4 4 4 14 4 14 5 3 13 9 10 10 2 10 9 10 6 11 5 3 12 6 8 4 5 9 3 12 8 9 2 3 5 10 11 2 12 5 2 10 Jordan 13 9 10 1 4 11 13 14 5 6 10 8 2 1 5 9 9 12 7 1 12 6 7 8 4 Vanuatu 2 5 8 10 14 10 3 9 8 12 13 15 5 9 15 13 10 4 4 6 9 7 14 11 13 Maldives Angola 15 12 7 12 2 7 8 14 2 7 7 15 14 10 5 6 13 15 7 14 6 7 9 11 13 8 7 15 3 12 5 15 15 8 8 11 6 15 4 13 11 5 4 15 8 15 13 15 14 6 Swaziland 6 8 4 11 6 1 8 2 10 11 12 13 9 11 1 10 12 14 2 15 7 13 11 12 11 Fiji Georgia 3 10 12 6 15 5 4 7 3 4 14 12 7 5 13 8 6 2 3 5 14 11 13 5 12 5 4 13 7 12 13 7 1 6 1 2 2 15 4 11 6 1 7 11 12 1 8 6 1 5 14 3 14 2 5 4 15 13 9 3 3 7 6 2 7 4 11 9 14 3 Syria Ranking of leading age-standardized rates of disability-adjusted life years (DALYs) relative to comparator countries in 2010 8 2 3 6 2 Breast cancer Diarrheal diseases Other cardio & circulatory Asthma Interpersonal violence Falls Other musculoskeletal Drug use disorders Hypertensive heart disease Neonatal encephalopathy Migraine 10 8 13 7 10 14 5 9 10 3 10 7 7 9 9 14 14 8 10 3 5 3 13 6 1 13 9 10 1 15 3 11 1 8 1 11 2 13 12 14 2 8 8 15 13 2 2 8 1 3 4 14 5 13 1 7 5 7 1 13 2 12 Namibia Neck pain Anxiety disorders 7 2 10 Chronic kidney disease Lower respiratory infections 6 5 8 COPD Low back pain 2 3 4 Iron-deficiency anemia Diabetes 15 1 6 Stroke Congenital anomalies 13 China Preterm birth complications Ischemic heart disease Turkmenistan Country Road injury Major depressive disorder Neck pain Diabetes 13 3 Anxiety disorders COPD 15 1 Hypertensive heart disease Road injury 15 2 Iron-deficiency anemia Stroke 13 9 Low back pain Lower respiratory infections 8 China Major depressive disorder Ischemic heart disease Turkmenistan Country Congenital anomalies Preterm birth complications Ranking of leading age-standardized rates of disability-adjusted life years (DALYs) relative to comparator countries in 1990 Samoa 3 2 1 13 9 5 2 3 2 8 5 12 12 8 13 7 12 15 15 2 3 9 3 7 5 Egypt 10 11 14 3 13 11 9 11 11 7 7 6 3 9 15 2 10 1 11 13 1 3 9 9 15 Guatemala Armenia 11 5 3 9 12 1 11 1 14 14 12 4 15 1 9 9 1 11 8 3 4 11 4 12 4 8 10 11 8 6 9 3 5 4 5 11 2 4 6 4 12 6 10 10 8 10 15 14 6 1 Jordan 15 8 15 11 15 8 7 4 6 4 13 9 10 3 12 1 11 4 6 12 2 2 13 5 6 Vanuatu 4 9 9 1 7 4 14 1 11 4 12 2 10 5 15 2 5 12 12 2 4 2 15 8 11 7 11 4 11 5 5 4 14 4 14 5 14 4 7 1 8 11 10 12 12 1 11 3 10 9 Maldives Angola 7 7 13 7 8 15 14 7 13 13 15 10 8 13 6 14 15 9 2 10 9 5 6 14 8 Swaziland 12 6 12 12 2 14 12 14 9 15 3 14 14 15 14 13 3 12 12 15 12 6 10 15 14 Fiji Georgia 2 14 9 15 10 4 15 8 3 9 6 13 6 5 10 6 8 13 13 5 7 8 15 8 7 5 13 6 4 1 7 6 12 10 6 10 3 5 7 1 11 9 6 7 11 15 13 11 2 13 Syria 14 12 10 5 14 3 4 6 8 1 9 7 1 2 7 3 5 3 5 6 6 4 2 4 11 Ranking Legend 1-3 Institute for Health Metrics and Evaluation 2301 Fifth Ave., Suite 600 Seattle, WA 98121 USA 4-7 8 - 11 12 - 15 Telephone: +1-206-897-2800 E-mail: [email protected] www.healthmetricsandevaluation.org Jordan | GBD | page 4
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