Caldwell Community College and Technical Institute Corporate and Continuing Education HEALTH SERVICES HEPATITIS B INFORMATION January 2012 8.14.14/dhs HEPATITIS B VIRUS INFORMATION The following information, taken from the Centers for Disease Control and Prevention website www.CDC.gov/hepatitis/B is provided to students enrolled in Health Service area courses through Corporate and Continuing Education (CCE). The purpose of this document is to inform the student of potential risks with contracting the disease. It is the student’s responsibility to read this material in order to recognize signs and symptoms, understand how the disease is transmitted, know who is at risk, and what measures should be taken to prevent contracting the disease. Hepatitis B Fact Sheet DESCRIPTION Hepatitis B is a contagious liver disease that results from infection with the Hepatitis B virus (HBV). It can range in severity from a mild illness lasting a few weeks to a serious, lifelong illness. Hepatitis B is usually spread when blood, semen, or another body fluid from a person infected with the Hepatitis B virus enters the body of someone who is not infected. HBV can be either acute or chronic and cause lifelong infection, cirrhosis (scarring) of the liver, liver cancer, liver failure, and death. Hepatitis B vaccine is available for all age groups to prevent hepatitis B virus infection. SIGNS & SYMPTOMS About 30% of persons have no signs or symptoms. Signs and symptoms are less common in children than adults. • • • • • jaundice fatigue abdominal pain fever clay-colored bowel movements CAUSE • Hepatitis B virus (HBV) TRANSMISSION • Occurs when blood from an infected person enters the body of a person who is not infected. HBV is spread through having sex with an infected person without using a condom (the efficacy of latex condoms in preventing infection with HBV is unknown, but their proper use might reduce transmission), by sharing drugs, needles, or "works" when injecting drugs, through needle sticks or sharps exposures on the job, by sharing razors or toothbrushes with an infected person, or from an infected mother to her baby during birth. Persons at risk for HBV infection might also be at risk for infection with hepatitis C virus (HCV) or HIV. HBV is NOT spread through food or water, sharing eating utensils, breastfeeding, hugging, kissing, hand holding, coughing, or sneezing. • • RISK GROUPS • • • • • PREVENTION 8.14.14/dhs • • Persons with multiple sex partners or diagnosis of a sexually transmitted disease Men who have sex with men Sex contacts of infected persons Injection-drug users Household contacts of chronically infected persons • • • • • • • • loss of appetite nausea, vomiting joint pain dark urine Infants born to infected mothers Infants/children of immigrants from areas with high rates of HBV infection Health-care and public safety workers with exposure to blood Hemodialysis patients Hepatitis B vaccine is the best protection. If you are having sex, but not with one steady partner, use latex condoms correctly and every time you have sex. The efficacy of latex condoms in preventing infection with HBV is unknown, but their proper use might reduce transmission. • • • • • • VACCINE RECOMMENDATIONS LONG-TERM EFFECTS WITHOUT VACCINATION • • • If you are pregnant, you should get a blood test for hepatitis B. Infants born to HBVinfected mothers should be given HBIG (hepatitis B immune globulin) and vaccine within 12 hours after birth. Do not shoot drugs; if you shoot drugs, stop and get into a treatment program; if you can't stop, never share drugs, needles, syringes, water, or "works", and get vaccinated against hepatitis A and B. Do not share personal care items that might have blood on them (razors, toothbrushes). Consider the risks if you are thinking about getting a tattoo or body piercing. You might get infected if the tools have someone else's blood on them or if the artist or piercer does not follow good health practices. If you have or had hepatitis B, do not donate blood, organs, or tissue. If you are a health-care or public safety worker, get vaccinated against hepatitis B, and always follow routine barrier precautions and safely handle needles and other sharps. Hepatitis B vaccine has been available since 1982. Routine vaccination of 0-18 year olds Vaccination of risk groups of all ages Chronic infection occurs in: • 90% of infants infected at birth • • 30% of children infected at age 1–5 years 6% of persons infected after age 5 years Death from chronic liver disease occurs in: 15%–25% of chronically infected persons CONTRAINDICATIONS TO VACCINE • A serious allergic reaction to a prior dose of hepatitis B vaccine or a vaccine component is a contraindication to further doses of hepatitis B vaccine. The recombinant vaccines that are licensed for use in the United States are synthesized by Saccharomyces cerevisiae (common bakers' yeast), into which a plasmid containing the gene for HBsAg has been inserted. Purified HBsAg is obtained by lysing the yeast cells and separating HBsAg from the yeast components by biochemical and biophysical techniques. Persons allergic to yeast should not be vaccinated with vaccines containing yeast. TREATMENT & MEDICAL MANAGEMENT • • HBV infected persons should be evaluated by their doctor for liver disease. Adefovir dipivoxil, interferon alfa-2b, pegylated interferon alfa-2a, lamivudine, entecavir, and telbivudine are six drugs used for the treatment of persons with chronic hepatitis B. These drugs should not be used by pregnant women. Drinking alcohol can make your liver disease worse. • • TRENDS & STATISTICS • • • • • 8.14.14/dhs Number of new infections per year has declined from an average of 260,000 in the 1980s to about 60,000 in 2004. Highest rate of disease occurs in 20-49-year-olds. Greatest decline has happened among children and adolescents due to routine hepatitis B vaccination. In the United States, an estimated 800,000 to 1.4 million persons have chronic HBV infection. Globally, chronic Hepatitis B affects approximately 350 million people and contributes to an estimated 620,000 deaths worldwide each year (http://www.cdc.gov/hepatitis/hbv/bfaq.htm ,2012). HEPATITIS B VACCINATION WAIVER OR CONSENT I understand that close personal contact with individuals may increase my risk of acquiring the hepatitis B virus (HBV) infection. By initialing and signing this form where appropriate, I acknowledge that I have read the information provided regarding HBV and have had adequate opportunities to ask questions regarding the material, and I agree to its content. Select one statement below and initial. Print your name; sign; date; return to instructor. ________ Initials _______ Initials _______ Initials _______ Initials I decline the hepatitis B vaccination at this time. I understand that I continue to be at risk for contracting this disease but hold Caldwell Community College and Technical Institute harmless should I contract the disease. Should I decide to receive the HBV vaccination series while participating in a health course through CCE, I will notify my instructor and clinical supervisor and will provide documentation of the vaccine(s) when given. I am currently receiving the series. I am submitting proof of immunizations. I am immune to hepatitis B. I am submitting proof of immunity. Hepatitis B vaccine is contraindicated for medical reasons. I am submitting medical documentation for verification. _______________________________________ Print name _______________________________________ Signature _______________________________________ Date 8.14.14/dhs
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