January 20, 2010 Welcome to BIO 311c A biology course that emphasizes principles and facts regarding living cells Lectures here (GRG 102) Mon., Wed., & Fri. at 9:00 a.m. Lecture 1 – Wed. 20 Jan. 2010 1 BIO 311C - Brand Instructor: Discussion Instructor: Textbook*: Web site: User ID: Password: Dr. J. Brand Rebecca Knight Biology, Campbell & Reece, 8th Edit. www.sbs.utexas.edu/brand/bio311c biosci\bio311c Prokaryotes! Carefully read the hand-outs that describe the course schedule, structure and content before the next lecture period. Information in the hand-outs will be reviewed briefly during the next lecture. UT is attempting to reduce the amount of circulated paper. We provide paper hand-outs of the initial course information but all subsequent information pertaining to this course will be provided electronically through our web site and BlackBoard. 2 *A paperback custom Volume 1 of the textbook covers most of the material assigned in BIO 311c. It is substantially less expensive than the hardbound complete textbook. Students who will enroll in BIO 311d are advised to purchase the complete textbook. * Presentation Slides Presentation slides corresponding to substantive contents of each lecture will be posted on the course web site and on BlackBoard by the afternoon of the day before the lecture. Not all slides pertaining to the mechanics of the course or general announcements will be posted. Slides that duplicate illustrations from reading assignments in the textbook will not generally be posted. On occasion a slide may be modified after a set of slides has been initially placed on the web site. These enhancements and/or corrections will be made within 24 hours after the corresponding lecture. If you prepare copies of the lecture slides, then be sure to inspect the posted slides at least one day after the corresponding lecture to be sure that your information corresponds to the latest version. Posted slides are shown with an asterisk in the lower-right corner of the slide. 3 * Printing PDFs of Presentation Slides If you wish to prepare a print version of the presentation slides, then you can save paper by printing the contents of multiple PDFs on a single page. file 4 print Page scaling (for example) 6 pages per sheet * BIO 311c Information that will be posted includes: - the course syllabus and general course information - most of the Presentation Slides used in lectures - notes from some of the discussion periods - exams for the previous semesters 5 * Discussion Periods - You are expected to attend your assigned discussion session each week. Attendance will be taken at each session. - Any regular change to a different discussion section time must be approved by the Discussion Instructor in advance. - Discussion sections will begin meeting this week (Jan. 22 & 25). - The first 2 weeks of discussion periods will focus on basic chemical background for BIO 311c. The subject matter will relate to information in Chapters 2 - 4 of the textbook (see (Lecture/Exam Schedule document). Introductory chemical information presented during the discussion periods and in the textbook will be included in exams. 6 * 7 * Subject Matter for Exams Exams will test your knowledge of information that is provided in: - textbook reading assignments - lectures* - presentation slides covering substantive course material - the first two discussion periods - other discussion periods (when inclusion on exams is announced in advance of the discussion period) *All subject matter presented during lectures may be included on the exams, regardless of whether or not it is placed on presentation slides. 8 * Getting Started Chapter 1 of your textbook provides context for the remainder of the textbook. You are encouraged to read that chapter, although it is not assigned reading for this course and we will cover only a few topics of Chapter 1 in lectures. We will begin discussing cells in detail (Chapter 6 of the textbook) during the next lecture. Today we will consider some basic principles of the living state and some general features of cells. 9 * BLACK-BOX PROPERTIES OF THE LIVING STATE It requires a continuous source of food (building material). It requires a continuous source of energy (fuel). It continuously generates waste products. Corollary: It exists in a state of homeostasis. 13 * Summary of black-box properties of a living organism Living Organism HOMEOSTASIS Food Energy Relatively constant contents and functions as food and energy are continuously incorporated and converted to cell components and waste products; Waste products a highly organized, low-entropy state; steady-state rather than equilibrium condition. 14 * Some levels of Organization of the Living State See Textbook Fig. 1.4, p. 4 The biosphere An ecosystem A community A population An organism 15 * Question: Into how small of units can a living system be divided such that the individual parts still maintain the black-box properties of the living state? 16 * Levels of Organization of the Living State (cont.) See Textbook Fig. 1.4, p. 5 An organelle A cell A molecule A tissue Living Organism An organ Display black-box properties of the living stare 17 Do not Display black-box Properties of the living stare * A living organism may be divided into units no smaller than single intact cells in order to retain the black-box properties of the living state. Individual Cell Food Energy HOMEOSTASIS Waste products Note: two problems must be overcome to allow a unit (a portion of a living organism) to remain alive. 1. There must remain way to get food & energy in, and waste products out, of the unit. 2. There must be appropriate communication within the unit. 18 * A Statement of THE CELL DOCTRINE - All living organisms are made up of one or more living cells. - The individual cell is the smallest unit of the living state. - Every existing cell has arisen from a pre-existing cell. 19 * SOME HISTORICAL MILESTONES IN CELL BIOLOGY THAT LED TO THE MODERN CELL DOCTRINE 1665: Robert Hooke first used the term "cell" to describe the empty compartments which were surrounded by thick cell walls in dead cork cells. 1680s: Anton van Leeuwenhoek, having become an excellent lensgrinder and microscopist, was the first person to recognize and record the fact that single-celled and few-celled organisms are all compartmentalized into discrete units (cells). 1830s: Mathias Schleiden (studying plants) and Theodor Schwann (studying animals) are credited with formalizing a cell theory which recognized the relatively independent existence of individual cells in a living organism. 1860s: Louis Pasteur presented strong experimental evidence for the non-existence of spontaneous generation, implying that cells must arise from pre-existing cells. 20 *
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