Name /bks_53161_deglins_md_disk/lycopene
02/17/2014 07:12AM
Plate # 0-Composite
pg 1 # 1
Interactions
Natural Product-Drug: None.
Natural-Natural Products: Absorption may be increased with beta carotene.
1
lycopene (lahy-kuh-peen)
Other Name(s):
all-trans lycopene, psi-psi-carotene
Classification
Therapeutic: antioxidants, cardioprotective agents, antineoplastics
Route/Commonly Used Doses
PO (Adults): Exercise-induced asthma— 30 mg/day; Prostate cancer— 15 mg
twice daily; Oral leukoplakia— 4– 8 mg/day.
NURSING IMPLICATIONS
Assessment
Common Uses
● Monitor for GI side effects (abdominal pain, flatus, diarrhea) periodically during
Atherosclerosis prevention. Exercise-induced asthma. Cancer prevention. Oral leukoplakia.
● Lab Test Considerations: Monitor lipid profile, serum androgen, and Prostate
therapy.
Specific Antigen (PSA) before and periodically during therapy.
Action
Lycopene is a predominant carotenoid in blood and tissues that has antioxidant properties. It scavenges free radicals and prevents oxidative damage to DNA. It may decrease cholesterol synthesis and remove LDL cholesterol from circulation. 85% of dietary lycopene comes from tomato-derived products. Therapeutic Effects:
Atherosclerosis prevention. Cancer prevention.
Potential Nursing Diagnoses
Pharmacokinetics
Absorption: Unknown.
Distribution: Unknown.
Metabolism and Excretion: Unknown.
Half-life: Unknown.
Patient/Family Teaching
Implementation
● PO: Administer as directed.
● Instruct patient to take as directed.
● Advise female patient to notify health care professional if pregnancy is planned or
suspected or if breast feeding.
Evaluation
TIME/ACTION PROFILE
PO
Deficient knowledge, related to medication regimen (Patient/Family Teaching)
ONSET
PEAK
DURATION
Unknown
Unknown
Unknown
● Decrease in atherosclerosis and exercise-induced asthma.
Why was this drug prescribed for your patient?
Contraindications/Precautions
Contraindicated in: Hypersensitivity.
Use Cautiously in: Pregnancy and lactation (when using amounts greater than
those found in foods).
Adverse Reactions/Side Effects
GI: diarrhea, abdominal pain, flatulence.
⫽ Canadian drug name.
⫽ Genetic Implication.
CAPITALS indicate life-threatening, underlines indicate most frequent.
Strikethrough ⫽ Discontinued.
PDF Page #1