G. Banfalvi
Apoptotic Chromatin Changes
2009, XII, 412 p. With DVD.
Printed book
Hardcover
▶ 239,00 € | £178.00 | $279.00
▶ *255,73 € (D) | 262,90 € (A) | CHF 262.50
▶ Shows the dynamic change of chromatin structures in a cell cycledependent manner
▶ Describes the intermediates of chromatin condensation
▶ Distinguishes between chromatin and chromosomal forms
▶ Describes how round shaped chromatin bodies, the first interphase
chromosomes, are converted to linear chromosomes
▶ Proves the linear attachment of chromosomes including interphase
and metaphase chromosomes
▶ Visualizes chromatin changes upon genotoxic treatment (chemical
carcinogenesis, heavy metal, irradiation)
▶ Provides the reader with additional information in the glossary
section
▶ Helps the reader with a detailed list of abbreviations
▶ Helps to understand three dimensionality and seemingly difficult
terms such as supercoiling
▶ Demonstrates that Drosophila chromosomes consist of smaller units
called rodlets
▶ Demonstrates that the nucleosomal arrangement of Drosophila
chromatin consist of meandering loops
▶ Reevaluates data of nucleosomal strings and provides a plectonemic
chromatin model of chromosome condensation in Drosophila cells
eBook
Available from your library or
▶ springer.com/shop
MyCopy
Printed eBook for just
▶ € | $ 24.99
▶ springer.com/mycopy
The Greek word apoptosis was used first by Hippocrates as a synonyme of dislocations of
the bones, structural changes related to tissue, by Marcus Aurelius in political and social
context as failure and decline. The physician Galen extended the medical meaning of
apoptosis to wound healing and inflammation.
Apoptosis, or cell suicide is an integral part of life cycle of plants and animals indicated by
the loss of 140-190g (50-70 billion) cells each day in the human adult, amounting to the
body weight in one year. The growing interest in apoptosis is indicated by the number of
scientific publications since the 1990s which is now more than 140,000 and will exceed
160,000 by the end of 2008.
The unique feature of this book is the use of synhronized and reversibly permeabilized
cells allowing to visualize the dynamic nature of chromatin condensation through
transitory chromatin and chromosomal forms including changes upon genotoxic
treatment, which were not seen earlier.
Order online at springer.com ▶ or for the Americas call (toll free) 1-800-SPRINGER ▶ or email us at:
[email protected]. ▶ For outside the Americas call +49 (0) 6221-345-4301 ▶ or email us at:
[email protected].
The first € price and the £ and $ price are net prices, subject to local VAT. Prices indicated with * include VAT for books; the €(D) includes 7% for
Germany, the €(A) includes 10% for Austria. Prices indicated with ** include VAT for electronic products; 19% for Germany, 20% for Austria. All prices
exclusive of carriage charges. Prices and other details are subject to change without notice. All errors and omissions excepted.