DEVELOPMENT OF TOOTH By: Assistant Professor Dr. Baydaa Ali Al Rawi Just for looking Stages in the life cycle of a tooth 1. Growth Physiologic process a. Initiation b. Prolifiration c. Histodifferentiation d. Morphodifferentiation e. Apposition 2. Calcification 3. Eruption Tooth Development A. Bud Stage B. Cap Stage C. Bell Stage D and E. Dentinogenesis and amelogenesis F. Crown formation G. Root Formation and eruption H. Function Three developmental process before function: 1. Grow 2. Calcify 3. Erupt Unlike kidney and heart.. Afte growth .. Function Unlike bone… growth and calcify… function MORPHOLOGICAL 1. Dental lamina 2. Bud stage 3. Cap stage 4. Early bell stage 5. Advanced bell stage 6. Formation of enamel and dentin matrix PHYSIOLOGICAL Initiation Proliferation Histodifferentiation Morphodifferentiation Apposition Just for looking Initiation of Tooth Development The initiation of tooth development begins at 6th weeks of development with formation of a continuous horseshoe-band of thickened epithelium in the location of upper and lower jaws – Primary Epithelial Band Each band of epithelium will give rise to 2 sub divisions: 1. Dental lamina and 2. Vestibular lamina Initiation stage 6th weeks intra uterine life: first sign of tooth development Dental lamina: represent the first sign of tooth development. DENTAL LAMINA continued and localized proliferative activity leads to the formation of a series of epithelial outgrowths into the mesenchyme at sites corresponding to the positions of the future deciduous teeth • At about 6th - 7th week the primary epithelial band divides into an inner (lingual) process called Dental Lamina & an outer ( buccal) process called Vestibular Lamina A - dental lamina B - vestibular lamina • Later during the development of jaws, permanent molars arise directly from the distal extension of the dental lamina • The successors of the deciduous teeth develop from a lingual extension of the free end of the dental lamina opposite to the enamel organ of each deciduous teeth. The lingual extension of the dental lamina is named the successional lamina & develops from the 5th month in utero ( permanent central incisor) to the 10th month of age (second premolar) Successional Lamina : It is a lingual extension of dental lamina. It is responsible for the development of permanent incisors , canine and premolars. Function of dental lamina: Function ofentire dental lamina 1. initiation of the deciduous dentition that begins at the 6 weeks of intra-uterin life of embryo. 2. initiation of the successors of the deciduous teeth. It is preceded by the growth of the free end of the dental lamina (successional lamina), lingual to the enamel organ of each deciduous tooth, and occurs from about the fifth month in embryo for the permanent central incisors to 10 months of age for the second premolar 3. preceded by the extension of the dental lamina distal to the enamel organ of the second deciduous molar and the formation of permanent molar tooth germs. Fate of Dental Lamina :- After initiation of tooth development , the dental lamina degenerates. Bud stage At certain point on DL representing the location of 10 manibular and 10 maxillary deciduous teeth cells multiply still more rapidly and form a knob like projections. Bud stage Bud stage is characterized by rounded, localized growth of epithelium surrounded by proliferating mesenchymal cells. Bud Stage In the bud stage, the enamel organ consists of peripherally located low columnar cells and centrally located polygonal cells Cap stage The epithelial bud will continue to proliferate and expand laterally Different part of the bud will show unequal growth leading to the formation of a cap stage dental organ( with invagination) 3. Bell Stage http://www.usc.edu/hsc/dental/ohisto/ Dental lamina Outer dental epithelium Inner dental epithelium Dental papilla Dental follicle Cervical loop • Continued growth leads to bell stage, where the enamel organ resembles a bell with deepening of the epithelium over the dental papilla • Continuation of histodifferentiation (ameloblasts and odontoblasts are defined) and beginning of morphodifferentiation (tooth crown assumes its final shape) ROOT FORMATION • The development of roots begin after enamel & dentin formation has reached the future cementoenamel junction • The enamel organ plays an important role in root development by forming HERS (Hertwig’s Epithelial Root Sheath), which models the shape of the root • HERS consists of outer & inner enamel epithelium only Question? Homework What are The meaning of successors ?
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