Introduction to Diabetes, Prediabetes, Metabolic Syndrome & Metabolic Repair A supplement to Dr. Pescatore’s Metabolic Repair Protocol: A drug-free plan for preventing and reversing type-II diabetes, prediabetes, and metabolic syndrome. Introduction to Diabetes, Prediabetes, Metabolic Syndrome & Metabolic Repair Prediabetes and diabetes have become national epidemics. According to the latest count, 29.1 million Americans have diabetes—that’s nearly 10% of the population. That number makes diabetes the 7th leading cause of death in this country, either directly or as a major contributing factor.1 These harrowing statistics are reason for alarm, but not for panic. Recent studies show that prediabetes can be reversed before the emersion of type 2 diabetes with the help of significant health and lifestyle changes. Those changes will all be recommended and explained my Metabolic Repair Plan. And that trend shows no sign of slowing. A 2014 report shows that the number of adults over 20 with prediabetes has jumped from 79 to 86 million between 2010 and 2012.2 If they don’t do anything to change their diet and exercise habits, up to a third of them will develop full-blown diabetes within the next 2 years.3 But first... What IS metabolic repair? In short, metabolic repair and, ultimately, metabolic balance, is when your body gets exactly enough nutrition to use it effectively and efficiently while functioning optimally. Unfortunately, far too many of us are in a state of metabolic imbalance, especially when it comes to sugar. What’s even scarier is that millions of Americans live with the disease and don’t even know it. That makes them 50% more likely to die than folks without diabetes.4 You’ve probably heard the terms metabolic syndrome and prediabetes. These relatively new terms are used to identify people who are in a state of metabolic imbalance. If left unchecked, either one of these conditions can lead to obesity and, eventually, type 2 diabetes. But diabetes will wreak havoc on a patient’s body and quality of life long before he or she succumbs to the disease. Recent statistics show that the vast majority of adults over 20 with diagnosed diabetes are far more likely to: According to the National Institutes of Health, metabolic syndrome is a combination of diabetes risk factors that includes: high BP, elevated triglycerides, low HDL cholesterol, a large waist or excessive abdominal fat, and increased insulin resistance. • Have dangerously high blood pressure of 140/90 or higher. • Suffer a stroke. • Die of cardiovascular disease. Insulin’s primary function is the removal of sugar from your blood so it can either be used for energy or stored. Insulin resistance is when your body starts requiring more and more insulin to achieve the same results. Whereas prediabetes occurs when you have mildly elevated blood sugar. • Be hospitalized for a heart attack.5 • Be diagnosed with diabetic retinopathy (damage to the blood vessels in the retina leading to vision problems/blindness).6 • Suffer from diabetes-related kidney failure. (There are about 230,000 adults on dialysis or in need of a transplant.)7 People with metabolic syndrome have a high risk of developing prediabetes and diabetes. But you can be insulin resistant without having elevated blood sugar.10 • Require a lower-limb amputation as a direct result of diabetic complications (affects about 73,000 diabetics a year).8 Finally, type 2 diabetes occurs when your sugar intake and the resultant insulin spikes wear down the pancreas’ ability to keep up, so that blood sugar levels become dangerously high. In other All told, diabetes costs the United States about $245 billion dollars in direct medical costs9 per year. 2 Introduction to Diabetes, Prediabetes, Metabolic Syndrome & Metabolic Repair Still, some of the first warning signs are just observational, like increased thirst and more frequent urination, especially at night. Unusual fatigue, consistent carb cravings, and blurred vision are also telltale signs. A measurable indicator of insulin resistance is elevated blood pressure – which often has no tangible symptoms at all. But dull headaches, dizziness, and nosebleeds could point to high BP. words, the body is no longer able to produce enough insulin to metabolize sugar properly. In some cases, the body stops producing insulin altogether. Sugar levels spike into dangerous levels, which puts you at risk for serious health complications. What should you be on the lookout for? The best way to know if you’re insulin resistant and/or have elevated blood sugar is to work with your doctor and ask him to run a blood test. There are two tests/numbers that can remove the guesswork from your prediabetes diagnosis: Other quantifiable symptoms include elevated triglycerides, decreased HDL cholesterol, and excess abdominal weight. Again, your doctor is best equipped to test for these levels and let you know if you’re at risk. • The first is your HbA1C. This test tells you how well-controlled your blood sugar has been for the past six weeks. An HbA1C under 5 is optimal. Between 5 and 5.6 is good. A result between 5.7 and 6.3 indicates prediabetes. And you officially become diabetic when this number goes above 6.3. In the prediabetes stages, you want to work towards getting your HbA1C back to the healthy range, below 5. But if you already have diabetes, trying to force the number down could be dangerous. A recent study showed that diabetics with HbA1C levels under 7 had the highest death risk.11 So diabetics should aim to keep theirs’ as close to 7 as possible. If you’re concerned, and have tried some online research, then I’m sure you’ve come across the “Diabetes Risk Test” on the American Diabetes Association’s website. It uses your age, weight, family history, ethnicity, height, blood pressure, and level of physical activity to determine how “at risk” you are for developing diabetes. The test is ineffective for many reasons, but the most critical is that it asks nothing about sugar consumption or any other symptoms, which are far more important than your age, or even your weight. So if you’re worried you may be at risk for diabetes, or that you’re already prediabetic, there’s a better list (see page 4) of questions you can use to self-evaluate. • The second number you need to know is your fasting blood glucose level, which measures the amount of sugar in your blood after at least 12 hours of fasting. A healthy fasting blood sugar level is between 70 and 80. If your number is 80-95, consider it a “yellow light”—you need to start taking precautions. If it’s between 95 and 110, you’re prediabetic. And anything over 110 is an indicator of diabetes until proven otherwise. If you answer yes to any of these questions, even if you’re not overweight, it’s likely you’re a candidate for prediabetes. Unfortunately, more than half the country would fail this test, but I’m here to help. Dangers and side effects of prescription diabetes drugs & outdated dietary advice To truly know where you stand on the path to diabetes, you need to know and understand these two numbers. Residents of most states can also order lab tests directly through a company called DirectLabs.® For more information go to www.directlabs.com/ovh1. Nowadays, when your doctor says you have “prediabetes,” he immediately puts you on a drug to try and prevent the full-blown disease. And the American Diabetes Association recently put out some “new-and-improved” guidelines for diabetes diagnosis that only lower the bar for healthy 3 Introduction to Diabetes, Prediabetes, Metabolic Syndrome & Metabolic Repair Let’s say you’re diagnosed with diabetes (or prediabetes), and your doctor prescribes a common medication called Actos. A 2011 study— conveniently sponsored by the drug’s manufacturer—wanted to see if Actos could prevent men and women with prediabetes from actually developing diabetes.12 What is your risk of diabetes? 1. Do you eat sugar? 2. Do you eat processed foods? 3. Do you eat white flour? 4. Do you drink beer or wine? And it was a success. Actos reduced their risk of developing the full-blown disease by a whopping 71 percent. All the major media outlets ran stories about the study—singing the praises of this “wonder” drug. 5. Do you sometimes feel “cravings” for sweets or salty foods? 6. Do you sometimes skip your exercise routine? 7. Do feel light-headed or sleepy in the afternoon? What they failed to mention is that Actos may increase your risk of bladder cancer, and the longer you take it, the higher your risk. The FDA is looking at the link between Actos and bladder cancer as we speak.13 8. Do you ever feel depressed? 9. Do you weigh at least 10 pounds more than you did in college? 10. Do drink diet soda? If that’s not enough of a condemnation, perhaps you recall Actos’ ugly twin brother, Avandia. Research showed that prediabetics who took Avandia also cut their risk of developing type 2 diabetes. But Avandia raises your risk of a heart attack.14 In fact, it’s considered so dangerous that use of the drug is strictly limited, and Europe has already banned Avandia altogether. 11. Do you drink regular soda? 12. Do you cook with Canola oil? 13. Do you eat margarine? 14. Do you find it hard to lose weight, even when you exercise? 15. Do you have less energy than you did in your 20s? Then there’s metformin, perhaps the most widely-recognized diabetes drug. It hit the market in 1977 and appears to be safer than Actos or Avandia. Studies show that it can reduce the progression to full-scale type 2 diabetes by 30 percent.15 In the rare instances when my Metabolic Repair Plan just isn’t enough, it’s one of the only drugs I’ll consider. A “yes” to any of the above puts you at risk! blood sugar even further. This opened the door for millions of previously “healthy” people to start taking long-term, heavy-duty drugs. But a 2002 study, published in the New England Journal of Medicine and sponsored by NIH and the American Diabetes association, compared the benefits of lifestyle changes to the efficacy of metformin for preventing type 2 diabetes.16 After three years, the lifestyle group was almost twice as likely to avoid type 2 diabetes. You may be asking yourself: “So why not just take the drugs and do what I want?” After all, drugs are universally perceived as the quick and easy fix. But just because there IS a drug, doesn’t mean it is good for you—or that it works. According to a recent study, the use of prescription drugs to keep an overly-tight rein on blood sugar causes serious health problems, with little-to-no benefits. If that’s not a rock-solid case for skipping the drugs whenever possible, consider a 2015 study 4 Introduction to Diabetes, Prediabetes, Metabolic Syndrome & Metabolic Repair published in the Journal of American Medical Association. Researchers at Yale found that, over a 10year period, using medications to tighten blood sugar control did not make diabetes patients any healthier.17 In fact, they experienced more low blood-sugar attacks, or hypoglycemia. Hypoglycemia can lead to abnormal heart rhythms, dizziness, and even loss of consciousness. • Lower C-reactive protein • Lower triglycerides These kinds of findings toss conventional wisdom right out the window. Cutting sugar is the key, not totally depriving yourself of fat or calories. Even certain carbs have their place on your dinner plate. The good news is, you can avoid these pitfalls altogether by giving your body the support it needs from the outset—without drugs. My Metabolic Repair Plan will show you how. There will be more specifics in the Metabolic Repair Plan itself; for now, just know that those low-fat, low-carb, low-calorie products are getting it wrong. At the end of the day, changing your diet and exercise habits is all it takes for successful metabolic repair, prediabetes reversal, and diabetes prevention. But even a drug-free approach to diabetes prevention has its challenges, particularly when it comes to making the right dietary changes. “Fat-free,” “low-calorie,” “artificially-sweetened”—these are all terms you’ll see on the foods that are supposed to slim your waistline and keep both obesity and diabetes at bay. Resources 1. http://www.diabetes.org/diabetes-basics/statistics/?loc= db-slabnav In reality, these conventional, mainstream protocols are not only doing more harm than good— they’re setting you up to fail. When food manufacturers take out fat, they add sugar and other unhealthy ingredients. In addition, low-fat diets can cause sharp drops in your good HDL cholesterol and dangerous spikes in your triglycerides. 2.Ibid 3.http://www.diabetes.org/diabetes-basics/statistics/cdcinfographic.html 4.http://www.diabetes.org/diabetes-basics/statistics/cdcinfographic.html 5.http://www.diabetes.org/diabetes-basics/statistics/?loc= db-slabnav Perhaps worst of all, they don’t contain enough good fat. Fat is extremely important to your body. It actually helps regulate your blood sugar, because fat takes longer for your body to digest. This prevents the all-too-familiar “sugar rush” by allowing the sugar to slowly drip into your bloodstream. Overall, fat helps your metabolism operate much more efficiently, which is what metabolic balance is all about. 6.Ibid 7.Ibid 8.Ibid 9.Ibid 10.http://www.pre-diabetes.com/prediabetes/is-prediabetesmetabolic-syndrome-x.html 11.http://journals.plos.org/plosone/article?id=10.1371/journal. pone.0068008 In a brand-new study published in the Annals of Internal Medicine, researchers found that low-fat diets may actually increase your risk of diabetes. Meanwhile, subjects who ate full-fat dairy products, like heavy cream and cheese, were actually 60 percent less likely to get diabetes.18 12.http://www.nejm.org/doi/full/10.1056/ NEJMoa1010949?query=featured_home&& 13.http://www.bmj.com/content/344/bmj.e3645 14.http://www.ncbi.nlm.nih.gov/pubmed/25166288 15.http://www.nejm.org/doi/full/10.1056/NEJMoa012512 16.http://www.nejm.org/doi/full/10.1056/ NEJMoa012512#t=article Plus, they had: 17.http://archinte.jamanetwork.com/article.aspx?articleid= 2089233#ArticleInformation • Less body fat • Higher good HDL cholesterol 18.http://annals.org/article.aspx?articleid=1900694 5 Introduction to Diabetes, Prediabetes, Metabolic Syndrome & Metabolic Repair Fred Pescatore, MD, is one of the most sought-after natural physicians in the country. He is the author of the New York Times best-selling book, The Hamptons Diet and the No. 1 best-selling children’s health book, Feed Your Kids Well, amongst others. Dr. Pescatore’s other books include: Thin For Good, The Allergy and Asthma Cure, The Hamptons Diet Cookbook and Boost Your Health with Bacteria. and surgery that come with countless side effects. And it’s not just his patients that are reaping the benefits. Dr. Pescatore features it all in one of the most exclusive health newsletters available, Logical Health Alternatives. A direct pipeline to one of the most respected minds in natural medicine, written by Dr. Pescatore himself. These cutting-edge cures and simple healing miracles are also shared daily with his loyal readers in his free e-letter Reality Health Check (Visit www.drpescatore.com). Dr. Pescatore has his finger on the pulse of natural medicine’s most cutting-edge cures. As a result, everyone from normal hardworking Americans to international royalty are traveling hundreds (sometimes even thousands) of miles to visit at his renowned clinic in New York City. After graduating medical school at Columbia University, Dr. Pescatore studied in Southeast Asia, India, Japan, Africa, and Europe. The techniques he gathered have become part of his broad knowledge of healing. He’s spent over 3 decades studying, researching and practicing medicine around the world alongside some of today’s most well respected physicians. His passion for traveling and education has given Dr. Pescatore vast opportunity to research and create some of the best nutritional supplements available today. Coming out with his own line in 2012, NuLogic Nutritionals, Dr. Pescatore has had hands-on experience formulating only the highest quality ingredients derived from ideal climates around the world. Through his non-stop research and unique medical connections across the globe he hears about the most groundbreaking natural discoveries and healing techniques as they happen…sometimes decades before they trickle out to the mainstream. Because of the respect Dr. Pescatore has earned in the nutritional supplement industry, he is a consultant for many firms and has been instrumental in developing and clinically testing many of the leading nutritional products. He is the President of the International and American Associations of Clinical Nutritionists, a member of the American College for the Advancement of Medicine, and belongs to many other professional organizations. With over 30 years of knowledge in his back pocket, Dr. Pescatore is putting the research, techniques, and in-depth healing protocols right in your hands–and not in clunky medical textbook fashion. Dr. Pescatore makes good health easy to understand and attainable for any age, at any fitness level. His natural approach to healing confronts the modern day cure-all obsession for drugs For more about Dr. Fred Pescatore’s Metabolic Repair Protocol, visit: www.ovhlearning.com also see: www.drpescatore.com © Copyright 2015, OmniVista Health Learning, L.L.C. 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