Monitor Unit Calculations for Photons and Electrons: Report of TGTG-71 John P. Gibbons1 and Donald M. Roback2 1Mary Bird Perkins Cancer Center Baton Rouge, Louisiana 2Maplewood Cancer Center Minneapolis, Minnesota AAPM Task Group 71 There is a need for AAPM to endorse a national protocol for MU calculations Recognizing this need, TGTG-71 was established TGTG-71 Membership: – John Gibbons (chair), Eric Klein, Kwok Lam, Don Roback, Roback, Jatinder Palta, Palta, Saiful Huq, Huq, John Antolak, Antolak, David Followill, Followill, Mark Reid (AAMD liason), liason), Faiz Khan (consultant) Outline TG71 Formation and Charge II. Photon Calculations III. Electron Calculations IV. Conclusions I. TGTG-71 Task Group Charge • Emphasize the importance of a unified methodology • Recommend of consistent terminology for MU calcs • Recommend measurement and/or calculation methods • Recommend QA tests • Provide example calculations for common clinical setups 1 TG71 Report Status Formulated in 2001 – First meeting 2001 AAPM Meeting – TwoTwo-year sunset date; Extended last year Draft report submitted to RTC 2004 Final report due end of 2004 TG71 Report Outline 1. Introduction 2. Nomenclature 3. Calculation Formalism 1. MU Equations 2. Input Parameters (Depth, Field Size) 4. Measurements 5. Interface to TPS 6. Quality Assurance 7. Examples Monitor Unit Calculations Overview • Accuracy within ±5% • Absolute versus Relative Dosimetry • Consistency with Treatment Plan • QA program Reference and Normalization Depths Reference depth (dref ): Defined within calibration protocols as the depth for measurement of absolute beam output. – TG51: dref = 10cm Normalization depth (d0): The depth at which all relative dosimetry functions (e.g., Scp, TPR) are set to unity. – Most clinics d0=dm 2 Outline Normalization vs. Reference Conditions I. Introduction II. Photon Calculations III. Electron Calculations IV. Future Efforts d0 dref dmax Nomenclature Photon Calculations Nomenclature Principals (3 Laws of Nomenclature) Law 1: Use commonly understood symbols Law 2: Maintain consistency with other TG reports, unless it conflicts with Law 1 Law 3: Avoid multiplemultiple-letter subscripts and/or variables, unless it conflicts with Laws 1 or 2 Constants D0’ d0 r0 SAD SSD0 Dose rate at normalization point Reference depth Normalization field size Source to Isocenter (Axis) Distance Source to Surface Distance under normalization conditions 3 d deff dm r rd rc Nomenclature Photon Calculations Nomenclature Photon Calculations Independent Variables Independent Variables Depth to point of calculation Effective or radiological depth Depth of maximum dose Field size at the surface Field size at the depth of the calc pt. Field size defined by the collimator jaws SPD SSD x Nomenclature Photon Calculations Nomenclature Photon Calculations Dependent Variables D OAR PDD PDDN Sc,p Sc Sp Dose to the calculation point OffOff-Axis Ratio Percentage Depth Dose Normalized Percentage Depth Dose Output Factor In Air Output Ratio Phantom Scatter Factor Source to (calculation) Point Distance Source to Surface Distance Off Axis Distance Dependent Variables TPR TF WF Tissue Phantom Ratio Tray Factor Wedge Factor 4 Depth of Normalization All quantities should be determined at this depth Recommended beyond the range of electron contamination Extrapolated dm for largest SSD, smallest r ESTRO Report recommends depth of 10cm. Reference Depth • TG71 Recommends d0=10cm • Why d0=10cm? 1. Consistency with TG-51 2. PDD(dmax) is inaccurate. 3. Electron Contamination at dm creates problems • TG71 Formalism Valid for d0= maximum dm Photon Calculation Formalism Photon Calculation Formalism Isocentric Calculation Technique Isocentric Calculation Technique c) b) a) d) r rc d SPD SPD d rd rd do SPD0 0 SPD r d rd g) SPD0 SPD x f) e) d) SPD 0 do SPD rc ro rd rd rd 5 Isocentric Calculations Isocentric Calculations Calculations to Arbitrary Points Calculation to the Isocenter D MU = D S ( r ) S ( r ) TPR(d , r ) WF ( d , r ) TF ' c 0 c p d d d SSD + d SAD 0 2 D S ( r ) S ( r ) TPR( d , r ) WF ( d , r ) TF OAR( d , x ) ' 0 NonNon-Isocentric (SSD) Calculations D S ( r ) S ( r ) PDD ( d , r , SSD ) WF ( d , r ) TF OAR (d , x ) ' 0 c c p d0 N c c p d d d SSD + d SPD 0 2 0 Determination of Field Size Method of Equivalent Square Rectangular fields may be calculated using the dosimetric quantities for an equivalent square: D 100% MU = D MU = 0 SSD + d SSD + d 0 2 0 0 – Equivalent Square Approximation: 4*A/P – Equivalent Square Tables (e.g (e.g,, Day and Aird, Aird, ‘83) Highly irregular fields may be calculated using a Clarkson integration These relationships should be verified for Sc 6 Determination of Field Size for Sc Determination of Field Size for Sc Sources of Head Scatter Open or Blocked (Cerrobend) Fields – Protocol uses Equivalent Square of Collimator Field Size – More accurate methods (e.g., PEV model) may be required if: Rectangular Fields of large aspect ratio Highly Irregular Fields • Backscatter to monitor chamber • Head Scatter • Adjustable Collimators • Flattening Filter Determination of Field Size for Sc Points Eye View Model Determination of Field Size for Sc Collimator Exchange Effect Defined: Sc(a,b) (a,b) ? Sc(b,a) (b,a) Demonstrated for Open and Wedged Fields Magnitude is typically < 2% 7 Determination of Field Size for Sc Determination of Field Size for Sc Determination of Field Size for Sc MLC Types Collimator Exchange Effect Points Eye View Model MLC Fields – Under PEV model, only apertures close to FF will effect Sc – Thus Field Size depends on MLC model Upper Collimator Replacement Lower Collimator Replacement Tertiary MLC Upper Jaw Replaced (Elekta) Lower Jaw Replaced (Seimens) Tertiary Collimation (Varian) 8 Determination of Field Size for Sc Collimator Scatter with MLCs Upper Jaw Replacement: – Palta found Sc best described by MLC field Lower Jaw Replacement: – Das found Sc best described by MLC field Tertiary Collimator: – Klein found Sc best described by collimator jaws Determination of Field Size Sp – Use effective field size at depth (isocentric) or at the normalization depth (SSD) TPR, WF – Use effective field size at depth PDDN – Use effective field size on the surface Determination of Field Size Other parameters are affected by the amount of scatter within the phantom material. Define the “Effective Field Size” Size” as the equivalent square of the field size incident on the phantom. This field size is reduced by – Custom Blocking/MLCs Blocking/MLCs – Missing Tissue (“ (“Fall Off” Off”) Determination of Depth Use of Heterogeneity Corrections Not universally used Importance of physician awareness Two possible methods for manual calculations – Ratio of TAR (RTAR) method – Power law TAR (“ (“Batho Method” Method”) 9 Measuring Dosimetric Parameters Photon Output Factors Photon Output Factors • Sc,p measured in phantom at reference depth • Important to separate collimator and phantom scatter • Sp usually determined indirectly: Sp = Scp Sp 6 MV, d=1.5 20 25 Field Size [cm] 30 35 40 Measuring Dosimetric Parameters 6MV Output Comparisons 6 MV, d=10 15 • Larger do will require mini-phantoms Sc 1.24 1.22 1.20 1.18 1.16 1.14 1.12 1.10 1.08 1.06 1.04 1.02 1.00 0.98 0.96 0.94 0.92 0.90 0.88 0.86 0.84 0.82 0.80 10 • Traditionally, measured with buildup cap Sc , p 6MV Output Comparisons 5 • Sc measured in air at reference depth. • Should avoid scatter from surrounding structures (support stands, floor, wall) Measuring Dosimetric Parameters 0 Measuring Dosimetric Parameters 45 1.24 1.22 1.20 1.18 1.16 1.14 1.12 1.10 1.08 1.06 1.04 1.02 1.00 0.98 0.96 0.94 0.92 0.90 0.88 0.86 0.84 0.82 0.80 6 MV, d=10 6 MV, d=1.5 0 5 10 15 20 25 Field Size [cm] 30 35 40 45 10 Measuring Dosimetric Parameters Sc 6MV Output Comparisons 1.24 1.22 1.20 1.18 1.16 1.14 1.12 1.10 1.08 1.06 1.04 1.02 1.00 0.98 0.96 0.94 0.92 0.90 0.88 0.86 0.84 0.82 0.80 Measuring Dosimetric Parameters 24 MV Photon Beams 6 MV, d=10 6 MV, d=1.5 0 5 10 15 20 25 Field Size [cm] 30 35 40 45 Measuring Dosimetric Parameters Which Sc to use? Frye et al., Med Phys 22 (1995) Measuring Dosimetric Parameters Which Sc? The Ratio of Dose Rates from these two scenarios is: D(d,rc,rd) / D(d,rc’,rd) = Sc(rc) / Sc(rc’) But… But…this is irrespective of normalization depth rd rd Explanation is found in Collimator Field Size dependence of other parameters (Sp, TMR) for d0=dm. 11 Measuring Dosimetric Parameters High Energy TMRs (18X) Measuring Dosimetric Parameters Wedge Factors 1.2 1.1 • Internal (Motorized) Wedges TPR(d,20x20,6x6) 1 • Single, large (e.g., 60o) wedge placed above jaws • Universal wedge concept TMR TPR(d,6x6,6x6) 0.9 • External Wedges 0.8 • Wedge placed below jaws by user • Selection of wedge angles available 0.7 0.6 0 5 10 15 Depth [cm] 20 25 Measuring Dosimetric Parameters WF Field Size Dependence • Extensively studied (>20 papers) • Review by Arrans et al., • SWD => Field Size Dependence • Not hold for Internal Wedges • RPC Review: WF=WF(R) if WF<0.65 12 Measuring Dosimetric Parameters WF Depth Dependence • McCullough et al., • Introduced RWF(d) • No significant effect >2% for d<10cm • RPC Review: WF=WF(d) if E<10MV or if WF<0.65 Determining Dosimetric Parameters Determining Dosimetric Parameters Filterless Wedge Factors EDW Factors EDW Factors – Direct Inspection of Final STT – Use of Normalized Golden STT – Analytic Equations VW Factors – Very close to unity for all Wedge Angles, Field Sizes – Exponential OffOff-Axis Relationship 13 Measuring Dosimetric Parameters Asymmetric Fields Filterless Wedges Off Axis Ratios Calculations to offoff-axis points may be performed in two methods: 1. Use of offoff-axis dosimetry functions 2. Use of CA dosimetry functions with a offoffaxis ratio: OAR(x,d,r) 1.4 1.2 1 0.8 VWF Measuring Dosimetric Parameters 0.6 0.4 0.2 0 -20 -15 -10 -5 0 5 10 OFFAXISDISTANCE Measuring Dosimetric Parameters Measuring Dosimetric Parameters OffOff-Axis Ratios OffOff-Axis Ratios OffOff-Axis Ratios have been determined in several ways 1. Large field profile data 2. Primary OffOff-Axis Ratios (POAR(x,d)) 3. Analytic Equations OAR Comparisons (Gibbons & Khan, ’95): [6, 24MV photons at 5,10,15cm OADs/depths OADs/depths] Large Field Profiles: POARs: POARs: Analytic Equation: Average (Max) Error 2.5% (6.7%) 0.8% (1.8%) 0.5% (1.7%) 14 Nomenclature Electron Calculations Outline Independent Variables I. Introduction II. Photon Calculations III. Electron Calculations IV. Future Efforts Nomenclature Electron Calculations Dependent Variables fair Se Air gap correction factor Electron Output Factor ra r g SSDeff Applicator size for electron beams Effective field size on the surface Difference between treatment SSD and normalization SSD (SSD0=100) Effective Source to Surface Distance Electron Calculations (SSD0=100cm) MU = D D S (r , r) ' 0 e a 15 Electron Calculations Electron Calculations (SSD>SSD0) (SSD>SSD0) Method 2: Air Gap Technique Method 1: SSDeff Technique MU = D D S ( r , r ) ( ( SSD + d ) ( SSD + d + g ) ) ' 0 e a eff 0 eff 0 Electron Output Factors 2 MU = D D S ( r , r ) ( ( SSD + d ) ( SSD + d + g ) ) ' 0 e a 0 0 2 f ( r , SSD ) air Electron Cone Inserts For square fields, Se measured at commissioning For rectangular fields, use Square Root Method: Se(ra,LxW) = [Se(ra,LxL) · Se(ra,WxW)]1/2 Many irregular fields can be approximated by rectangular fields. From Hogstrom et al., “MU Calculations for Electron Beams”, 2000 16 Electron Irregular Fields Electron Irregular Fields Special considerations required if FS very small (r < E/2.5) For these conditions, Se may be determined by – Special Dosimetry – Method of Lateral Buildup Ratio (LBR) Electron Irregular Fields S =D e ' 0 PDD f 100% a f LBR i Electron Extended SSD Calculations Many treatment geometries require extended SSDs Where PDD is the percentage depth dose for a broad field fa is the ratio of applicator to reference fluence fi is the ratio of insert to reference fluence LBR is the average lateral buildup ratio LBR is the ratio of the central axis depth dose in a given circular field to the central axis depth dose in a broad field for the same incident fluence - measured data The Air Gap Factor may be determined – Using inverse square correction with virtual SSD requires air gap scatter correction term – Using inverse square correction with effective SSD 17 Electron Extended SSDs Electron Extended SSDs From Roback et al., “Effective SSD for Electron Beams …”, Med Phys 1995 Conclusions Task Group 71 of the RTC was formed to create a consistent nomenclature and formalism for MU Calculations For photon beams, TG71 recommends a normalization depth of 10cm, although the formalism is valid for (maximum) dm. For electron beams, TG71 allows for both effective SSD or Air Gap correction methods for extended SSD calculations 18
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