How did scientists determine that DNA is responsible for storing, copying and
transmitting genetic information? How was the basic structure of DNA
discovered?
What if? A World Without Code - DNA
5. DNA to DNA: Replication
3’
Template
Strand
T
5’
Complementary Strand
A
1. Make a list of things that we take for granted every day
that would not be possible if we had no knowledge of DNA or
its structure.
C
T
C
A
C
A
2. What did the scientist, Mark Kershner, mean by saying that
the discovery of the double helix is the ‘bedrock of all
biology?’
T
C
G
C
C
T
3. In what way was the structure of DNA an iconic discovery?
(An icon is something that is revered or intensely admired.)
5’
3’
Draw an arrow above in the direction the new complementary
strand is replicating.
Identify the role of each enzyme in the replication process:
Helicase:
4. “How does the structure of the double helix ensure that all
cells of any organism get the same genetic code?”
DNA Polymerase:
Ligase:
The Secret of Life – Discovery of DNA Structure
1.
What are some common uses of DNA technology today?
The Secret of Life – Discovery of DNA Structure
1.
What are some common uses of DNA technology today?
2. Prior to the discovery that DNA is the genetic material,
what was the focus of heredity on?
2. Prior to the discovery that DNA is the genetic material,
what was the focus of heredity on?
3. What role did electron microscopes have on determining the
basis of life?
3. What role did electron microscopes have on determining the
basis of life?
4. Eric Lander, says “… it is perhaps more than anything the
work of an extraordinary community that both cooperates
and competes at the same time.” Why is the discovery of
the “secret of life” a classic example of this form of
scientific cooperation and competition?
4. Eric Lander, says “… it is perhaps more than anything the
work of an extraordinary community that both cooperates
and competes at the same time.” Why is the discovery of
the “secret of life” a classic example of this form of
scientific cooperation and competition?
5. Why were James Watson and Francis Crick
5. Why were James Watson and Francis Crick
“unlikely characters?”
6. Why didn't a triple helix model, suggested by Linus
Pauling, work to explain DNA structure?
7. Rosalind Franklin, was an expert in X-ray crystallography.
Explain what this is.
“unlikely characters?”
6. Why didn't a triple helix model, suggested by Linus
Pauling, work to explain DNA structure?
7. Rosalind Franklin, was an expert in X-ray crystallography.
Explain what this is.