1-B. QQ Plot
0.8
0.6
0.4
0.0
0
2000
4000
6000
8000
0.0
0.2
0.4
0.6
0.8
1.0
European Allele Frequency
1-C. Histogram of MAF of European Population
1-D. Histogram of MAF of African Population
4000
Frequency
4000
0
0
2000
6000
6000
8000
8000
Index
2000
Frequency
0.2
African Allele Frequency
0.0 0.2 0.4 0.6
-0.4
European - African
1.0
1-A Allele Frequency Difference of European and African
0.00
0.02
0.04
0.06
MAF of European
0.08
0.10
0.00
0.02
0.04
0.06
0.08
0.10
MAF of African
Supplementary Figure 1: Allele frequency distribution in simulated European and African populations. 1-­‐A: Allele frequency difference of European versus African populations; 1-­‐B: QQ plot of African allele frequencies versus European allele frequencies; 1-­‐C: Histogram of minor allele frequency in European population; 1-­‐D: Histogram of minor allele frequency in African population.