The University of Texas Health Science Center at San Antonio
MD/PhD 7th Annual
Retreat
Volume 5 Issue 2
March 5, 2016
GCCRI
Keynote Speaker
MD/PhD Students receive fundable scores from NIH National
Research Service Awards
Carl H. June, MD
Alumni Speaker
Suzanne Thibodeaux, MD, PhD
2nd Visit for MD/PhD
Students
March 4-5,2016
Academic Learning &
Teaching Center Dedication
February 16th @ 11AM
Inside this issue:
MD/PhD Program
News
1
Student Academic
News
Student Publications
3
MD/PhD Recruitment
4
Save the Dates
4
Congrats to our three MD/PhD GS2 students who received NIH National Research Service Awards! (L-R) Brett Ipson who is mentored by Dr. Alfred Fisher received
1F30AG053034 entitled “Contribution of m-tyrosine to the adverse effects of oxidative
stress.” Curtis Clark is mentored by Dr. Tyler Curiel received 1F30CA206398-01
Entitled “ Novel PD-L1 signals regulating anti-tumor immunity and immunotherapy responses” and Jeffery Cooney is mentored by Dr. Ricardo Aguiar received
1F30CA206343-01 entitled “The cyclic AMP/phosphodiesterase4 axis regulates proximal
B cell receptor signaling and offers a new therapeutic strategy for B cell lymphomas.”
Jessica Zavadil Co-first author publication
Jessica Zavadil, GS4, a co-first author publication
in Cancer Prevention Research. The article is entitled “DNA Alkylating Agent Protects Against Spontaneous Hepatocelluar Carcinoma Regardless of O6Methylguanine-DNA Methyltransferase Status.” Jessica is mentored by Dr. Christi Walter, Cancer Biology.
Curtis Clark & Justin Drerup on their way to Switzerland
Curtis Clark, GS-2, and Justin Drerup, GS3 will be
heading to Davos Switzerland in March to attend the World
Immune Regulation Meeting. Curtis will be presenting a
poster on “Tumor-intrinsic B7-H1 signals in melanoma and
ovarian cancer regulate tumor mTOR, growth, autophagy
and immune sensitivity” and Justin will be giving an oral
presentation on “IL-2 blockade by anti-CD25 antibody depletes central regulatory T cells, improves tumor immunity,
and extends survival in an ovarian cancer model..” Both students are mentored by Dr. Tyler Curiel. Way to go guys!!
MD/PhD 7th Annual Retreat Keynote Speaker
Carl H. June, MD
Professor of Medicine, Pathology and Laboratory Medicine
Director, Center for Cellular Immunotherapies at the
University of Pennsylvania
Alumni Guest Speaker
Suzanne R. Thibodeaux, MD, PhD
Resident
Department of Pathology and
Laboratory Medicine
Hospital of the University of Pennsylvania
MD/PhD Interview
Appreciation Breakfast
The MD/PhD Program students were a big help during
Interview season for AY16 candidates and were treated to
breakfast at Magnolias. A big “thank you” to these students
for taking the time out of their busy schedules to help and
assist with interviews! Your participation is greatly appreciated!
Page 2
MD/PhD Student Publications 2015-2016
Volume 5 Issue 2
Callaway DA, Riquelme MA, Sharma R, Lopez-Cruzan M, Herman BA, and Jiang JX. Caspase-2 Modulates Osteoclastogenesis through
Down-regulating Reactive Oxygen Species. Bone. 76: 40-48. 2015.
Callaway DA and Jiang JX. Reactive Oxygen Species and Oxidative Stress in Osteoclastogenesis, Skeletal Aging, and Bone Diseases.
JBMM. 33(4):359-370. 2015.
Dao V, Pandeswara S, Yang L, Hurez V, Dodds S, Callaway DA, Ai-Jie L, Sharp ZD, Hasty P, and Curiel T. Prevention of carcinogen and
inflammation-induced dermal cancer by oral rapamycin includes reducing genetic damage. Cancer Prevention Research. 8(5):400-409. 2015
Xu H, Gu S, Riquelme MA, Burra S, Callaway DA, Cheng H, Guda T, Schmitz J, Fajardo RJ, Werner SL, Zhao H, Shang P, Johnson ML,
Bonewald LF, Jiang JX. Connexin 43 Channels are Essential for Normal Bone Structure and Osteocyte Viability. J Bone Miner Res. 30(3):55062. 2015.
Dao V, Srilakshmi Pandeswara, Yang Liu, Vincent Hurez, Sherry Dodds, Danielle Callaway, Aijie Liu, Paul Hasty, Zelton Dave Sharp, Tyler
J. Curiel. Prevention of carcinogen and inflammation-induced dermal cancer by oral rapamycin includes reducinggenetic damage. Cancer
Prevention Research. 2015 Mar 3. 25034342
Hurez V, Dao Vinh, Liu A, Pandeswara S, Gelfond J, Sun L, Bergman M, Orihuela CJ, Galvan V, Padrón Á, et al. Chronic mTOR inhibition
in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune-deficient mice. Aging Cell.
2015 Aug 28. PubMed PMID: 26315673.
Heisler JM, et al. Indoleamine 2,3-dioxygenase-dependent neurotoxic kynurenine metabolism mediates inflammation-induced deficit in
recognition memory. Brain Behav Immun. 2015.
Melton DW, McManus LM, Gelfond J, Shireman PK. Temporal Phenotypic Features Distinguish Polarized Macrophages In
Vitro.Autoimmunity 31:1-16.
.Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-Koretskaya L, Abdool Karim S, Martin JN, Deeks SG,
Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung'u T, Hunt PW, He W, Ahuja SK. Epigenetic
mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor Proc Natl
Acad Sci U S A. 2015 Aug 25;112(34):E4762-71. doi: 10.1073/pnas.1423228112. Epub 2015 Aug 11.
Starr P, Bartels, Agrawal, Bailey. "Evolution of Micromachined Pressure Transducers for Cardiovascular Applications." Sensors and Actuators A 225 (2015) 8-19.
Starr, Peter, C. Agrawal, and Steven Bailey. "Biocompatibility of common polyimides with human endothelial cells for a cardiovascular
microsensor."Journal of Biomedical Materials Research Part A 104, no. 2 (2016): 406-412. (Volume 104, Issue 2, pages 406–412, February
2016).
DNA Alkylating Agent Protects Against Spontaneous Hepatocellular Carcinoma Regardless of O6-Methylguanine-DNA Methyltransferase
Status Maryanne C. Herzig, Jessica A. Zavadil, Karah Street, Kim Hildreth, Norman R. Drinkwater, Traci Reddick, Damon C.
Hebert, Martha A. Hanes, C. Alex McMahan, Robert L. Reddick, and Christi A. Walter. Cancer Prev Res canprevres.0251.2015; Published
OnlineFirst December 14, 2015; doi:10.1158/1940-6207.CAPR-15-0251
Zhou JZ, Riquelme MA, Gao X, Ellies LG, Sun LZ, Jiang JX. Differential Impact of Adenosine Nucleotides Released by Osteocytes on Breast
Cancer Growth and Bone Metastasis. Oncogene. 2015: 34, 1831-1842. (PMCID: PMC4315766).
Save the Date!
Academic Learning & Teaching Center Dedication
February 16th
11AM-1PM.
Pa
GSBS May & June 2016 Graduation
Save the Dates
7th Annual MD/PhD Program Retreat
Saturday, March 5, 2016
Featuring:
Carl June, MD, PhD
Associate Professor of Medicine
GSBS Commencement Ceremony– May 20, 2016
GSBS Degree Conferral– June 30, 2016
More info on graduation timeline on: http://gsbs.uthscsa.edu/
current_students/graduation-information
*All students who are eligible to participate in the May 20th GSBS
Commencement Ceremony can begin ordering their regalia in
the campus bookstore.
2nd Visit for AY16 Applicants
March 4-5,2016
The schedule for MD/PhD Journal Club for the
academic year is below. Journal Club will be
from 12:00PM-1:00PM.
January 22nd
February 19th
March– No Journal Club
MD/PhD Recruitment Events
Texas Swing 2016
April 15th
May 13th
UT Austin Health Professions Fair
Wednesday, Feb. 24th from 10AM-2:30PM
UTSA Health Professions Day
Thursday, Feb. 25th from 9:30AM-1:30PM
DFW Spring Swing 2016
Austin College– Tuesday, April 5th from 11:00AM-1:00PM
Bench to Bedside
The schedule for Bench to Bedside Seminars for
the academic year is below. Bench to Bedside
will be from 5:30PM-7:00PM.
University if Texas at Dallas April 5th from 3:30PM-6:00PM
TCU– Wednesday, April 6th from 12:00PM-2:30PM
SMU & University of Dallas– Wednesday, April 6th 5:00PM-7:30PM
January 11th
February 8th
March– No B2B
University of Texas at Arlington- Thursday, April 7th from 12:00PM2:30PM
April 11th
University of North Texas—Thursday, April 7th from 5:00PM-7:30PM
May 9th
June 13th
UT Austin MD/PhD Event
April 14th & 15th
*Current students will participate in a panel discussion, poster judging and
recruitment.
July 11th
B2B Locations are TBD.