Safety Data Sheet
According to REG (EC) no.453/2010
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Date of Compilation : June 27th, 2011
Date of Revision
: June 27th, 2011
Revision Number
: 03
Version Number
: 0044D01 Div 01 sds Ethyl Acetate
Supersedes date
: December 16, 2010
Supersedes version
: 0044C02 Div 01 sds Ethyl Acetate
Jubilant Life Sciences Limited
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Safety Data Sheet
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
SECTION 1.: IDENTIFICATION OF THE SUBSTANCE AND OF THE COMPANY
1.1 Product identification: Ethyl Acetate CAS RN 141-78-6; EC# 205-500-4
1.1.1. Trade name: Ethyl Acetate
1.1.2. Systematic Name: Acetic acid ethyl ester, Ethyl acetate
1.1.3. Synonyms: Ethyl acetic ester, Ethyl ester, Ethyl ethanoate, Acetoxyethane .
1.1.4. Other Languages:
1.1.5 Molecular Formula
De: Ethylacetat
Es: Acetato de etilo
Fr: Acétate d'éthyle
C4H8O2
1.1.6. Structural Formula:
O
H3C
CH3
O
1.1.7. Registration Status under REACH Regulation (EC) No. 1907/2006
EC Name
Submission Number Registration Number
Name of the Organization(OR)
Ethyl acetate
YW194220-03
Jubilant Pharmaceuticals NV
01-2119475103-46-0008
1.2 Identified uses: It is used in Industrial formulation, as an extraction solvent/processing aid, in Industrial
application of paints, coatings and other mixtures containing ethyl acetate by way of spraying and also as a
laboratory reagent.
Jubilant Life Sciences Limited
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
1.3 Uses advised against: None
1.3 Company / supplier: FACTORY & REGISTERED OFFICE:
Jubilant Life Sciences Ltd.
(Formerly, Jubilant Organosys Limited)
Bhartiagram, Gajraula
District: Jyotiba Phuley Nagar
Uttar Pradesh-244223 , India
PHONE NO: +91-5924-252353 unto 252360
Contact Department-Safety: Ext. 7424
FAX NO : 91-5924-252352
HEAD OFFICE:
Jubilant Life Sciences Ltd.
(Formerly, Jubilant Organosys Limited)
Plot 1-A, Sector 16-A,
Institutional Area, Noida,
Uttar Pradesh-201301 India.
PHONE NO: +91-120-2516601
FAX NO : +91-120-2516834
Email: [email protected]
Website: www.jubl.com
1.3 Emergency telephone: Medical and Transport Emergencies: +91-9997022412 (India)
Logistics emergencies: +91-120-4365441. (India).
Jubilant Life Sciences Limited
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
SECTION 2:
HAZARDS IDENTIFICATION
2.1.1 Classification of the substance according to Regulation (EC) 1272/2008 (Annex VI)
Flammable liquid: Category 2
STOT single exposure: Category 3
H225
H336
2.1.2 Classification as per Directive 67/548/EEC
F; R11 - Xi; R36 - R66 - R67
F: Flammable
Xi: Irritant
2.2 Label elements according to regulation (EC) 1272/2008
Pictograms:
GHS02 – flammable
Signal word:
GHS07 – exclamation
Danger!
Hazard and precautionary statements:
Hazard Statements


H225: Highly flammable liquid and vapour.
H336: May cause drowsiness or dizziness.
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
PRECAUTIONARY STATEMENTS
Prevention
 P233: Keep container tightly closed.
 P240: Ground/bond container and receiving equipment.
 P241: Use explosion-proof electrical/ventilating/lighting/.../ equipment.
 P242: Use only non-sparking tools.
 P243: Take precautionary measures against static discharge.
 P280: Wear protective gloves/protective clothing/eye protection/face protection.
 P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
 P271: Use only outdoors or in a well-ventilated area.
Response
 P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing.
Rinse skin with water/shower.
 P370+P378: In case of fire: Use ... for extinction.
 P403+P235: Store in a well-ventilated place. Keep cool.
 P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for
breathing.
 P312: Call a POISON CENTER or doctor/physician if you feel unwell.
Storage
 P403+P233: Store in a well-ventilated place. Keep container tightly closed.
 P405: Store locked up.
Disposal
 P501: Dispose of contents/container to local/regional/national/international regulations.
2.3 Other Hazards

Substance is not classified as PBT nor as vPvB. For further details see section 12.
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
SECTION 3:
COMPOSITION / INFORMATION ON INGERDIENTS
Classification according to Reg (EC) No.
1272/2008
Sr.No.
1
Chemical
Ethyl
acetate
CAS #
141-78-6
EC#
205-500-4
Purity
Hazard
classes and
categories
~ 100% Flammable
Liquid:
Hazard
Category 2;
Pictograms
signal word
Hazard
statements
GHS 02,
GHS07
H225
H336
STOT single
exposure:
Hazard
Category 3
Classification and labeling acc. to Dir. 67/548/EEC
Classification
Symbol
Risk Phrases
R11 ; R36 ; R66; R67
F: Flammable
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Xi: Irritant
SECTION 4:
FIRST AID MEASURES
4.1. Description of first aid measures.
4.1.1 Route of exposure: inhalation, skin and eye
4.1.2 Advice



Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Call a POISON CENTER or doctor/physician if you feel unwell.
4.2. Most important symptoms and effects, both acute and delayed.


Acute effects:
Inhalation results in drowsiness, cough, nausea and headache. Skin exposure can lead to dry skin. Eye
exposure can lead to redness and possible irritation.
Chronic effects:
After skin contact: Degreasing effect on the skin possibly followed by secondary inflammation. After
long-term exposure to the chemical: Sensitization with allergic manifestations have been reported.
4.3. Indication of any immediate medical attention and special treatment needed.




Eyes: If in eyes rinse cautiously with water for at least 15 minutes. Remove contact lenses if easy to do
so. Continue rinsing. Seek medical attention.
Skin: Immediately take off all contaminated clothing. Wash thoroughly with water for at least 15
minutes. Wash contaminated clothes before reuse. Seek immediate medical attention.
Inhalation: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a
physician if you feel unwell.
Ingestion: If swallowed call a poison center if you feel unwell. Rinse mouth. Do NOT induce vomiting
by use of emetics. Seek medical attention.
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
SECTION 5 :
FIRE-FIGHTING MEASURES
5.1. Extinguishing media.

Dry chemical powder, carbon dioxide and alcohol resistant foam. Avoid using water. In very large fires
one may use water spray, fog or alcohol-resistant foam by directing streams to the periphery of the fires
to prevent spread.
5.2. Special hazards arising from the substance

Flashback along vapor trail may occur. Closed container exposed to heat may explode. Contact with
strong oxidizer may cause fire .
5.3. Advice for firefighters.







Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Keep the containers cool by spraying water if exposed to heat or fire. Move containers out of hazard
area if safe to do so.
Fight fire from maximum distance or use unmanned hose holders or monitor nozzles.
Cool containers with flooding quantities of water until well after fire is out
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
Always stay away from tanks engulfed in fire.
For massive fire, use unmanned hose holders or monitor nozzles; if this is impossible, withdraw from
area and let fire burn.
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions;
also, consider initial evacuation for 800 meters (1/2 mile) in all directions.
SECTION 6 :
ACCIDENTAL RELEASE MEASURES
6.1. Personal precautions, protective equipment and emergency procedures.
6.1.1 For non-emergency personnel


Wear protective clothing, full boots, impervious gloves, safety glasses and Self Contained Breathing
Apparatus (SCBA), as may be deemed appropriate.
Avoid breathing vapors and contact with skin and eyes.
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011





Shut off leak source if possible.
Shut off all possible sources of ignition.
Wipe up.
Decontaminate all equipment.
Use non-sparking tools.
6.1.2 For emergency personnel






Wear protective clothing, full boots, impervious gloves, safety glasses and Self Contained Breathing
Apparatus (SCBA), as may be deemed appropriate.
Alert Emergency Responders and tell them location and nature of hazard.
Shut off all possible sources of ignition and increase ventilation.
Stop leaks if possible.
Clean up all spills immediately following relevant Standard Operating Procedures.
Avoid breathing vapors and contact with skin and eyes.
6.2. Environmental precautions.







Clean up all spills immediately following relevant Standard Operating Procedures.
Inform authorities in event of contamination of any public sewers, drains or water bodies.
Wipe up.
Prevent, by any means available, spillage from entering drains or water and watercourses.
Collect recoverable product into labeled containers for recycling, recovery or disposal.
Contain spill with sand, earth or vermiculite.
Spread area with lime or absorbent material, and leave for at least 1 hour before washing.
6.3. Methods and material for containment and cleaning up.
6.3.1:Containment of the spill.
(a) Bunding, covering of drains.
(b)Capping procedure.
 Clean up all tools and equipment.
 Decontaminate all equipment.
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
6.3.2 Cleanup procedure ( Any of the following)
(a)Neutralization techniques;
(b) Decontamination techniques;
( c )Adsorbent material;
(d) Cleaning Techniques;
(e) Vacuuming techniques;
(f) Equipment required for containment/Cleanup(include the use of non-sparking tools and equipment where
applicable)
6.4. Reference to other sections.
 Refer to section 8 and 13.
SECTION 7:
HANDLING AND STORAGE
7.1. Precautions for safe handling









Do not breathe vapor or mist.
Wear protective gloves/clothing and eye/face protection.
Wash thoroughly after handling.
Ground and secure containers when dispensing or pouring product.
Avoid contact with incompatible materials.
When handling, DO NOT eat, drink or smoke.
Launder contaminated clothing before re-use.
If on skin or hair, IMMEDIATELY remove all contaminated clothing and rinse/shower with
plenty of water.
Use in a well ventilated place/Use protective clothing commensurate with exposure levels.
7.2. Conditions for safe storage, including any incompatibilities



Store in a cool, well ventilated place.
Store in a flame proof area.
Store away from incompatible materials.
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011


Keep only in original container.
Keep securely closed when not in use.
7.3. Specific end use(s)






Industrial formulation of ethyl acetate and its mixture
Industrial use as an extraction solvent and/or processing aid
Industrial Application of Paints, Coatings and other Mixtures containing Ethyl Acetate by way of
Spraying
Industrial Application of Paints and Coatings \(non-spray application)
Industrial and Professional (end) use of ethyl acetate as a laboratory reagent
SECTION 8 :
EXPOSURE CONTROLS / PERSONAL PROTECTION
8.1. Control parameters
8.1.1 Exposure Limits Values







NIOSH REL: TWA 400 ppm (1400 mg/m3)
OSHA PEL: TWA 400 ppm (1400 mg/m3)
ACGIH 1997: TLV: 400 ppm; 1440 mg/m3
IDLH: 2000 ppm
OEL-AUSTRALIA: TWA 400 ppm (1400 mg/m3)
OEL-THE PHILIPPINES: TWA 400 ppm (1400mg/m3)
NDS –POLAND: 200 mg/m3
8.1.2 DNELS/ PNEC
PNEC
Water
(Freshwater)
0.26 mg /L.
Jubilant Life Sciences Limited
Sediment
(Freshwater)
1.25mg/kg
sediment dry wt.
Soil
0.24 mg/kg soil dw
Sewage treatment
plant
650 mg/L
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
DNEL
Dermal
Inhalation
Oral
Workers
General Population
63 mg/kg bw/day
37 mg/kg bw/d
734 mg/m³
734 mg/m3
4.5 mg/kg bw/d
8.2. Exposure controls
8.2.1
Appropriate Engineering Controls:
This substance has been registered as a transported isolated intermediate and is used under strictly
controlled condition. Provide exhaust ventilation or other engineering controls to keep the relevant
airborne concentrations below their respective occupational exposure limits. Local ventilation is
usually preferred. Ensure that eyewash stations and safety showers are close to the workstation
location.
8.2.2 Personal Protection:





Protective clothing should be selected specifically for the working place, depending on concentration
and quantity of the hazardous substances handled. The resistance of the protective clothing to chemicals
should be ascertained with the respective supplier.
Eyes: Safety goggles/ Chemical Safety glasses and Face shield.
Hands: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Boots and clothing to prevent contact.
Respirator: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard
EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
SECTION 9 :
PHYSICAL AND CHEMICAL PROPERTIES
9.1. Information on basic physical and chemical properties.
Sr.No.
Parameter
Typical value
a) Appearance
Colourless liquid
b) Odor
Ether like fruity odour
c) Odor Threshold
0.96 - 176.9 ppm
d) pH
Not available
e) Melting point/Freezing point
(-) 84C (Melting point)
f) Boiling point
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g) Flash point
77.15 C
(-) 4.4 C, closed cup
h) Evaporation rate (n-BuAc=1)
4.2
i) Flammability (Solid, gas)
Flammable Liquid
j) Upper/lower flammability or
Explosive limits
2.1%-11.5%(Explosive limit)
k) Vapor pressure
124.79 hPa at 20 C
l) Vapor density (air=1)
Not available
m)Relative density
0.902@ 20 C
n) Solubility
83g/l at 20C; 80g/l at 25C
o) Log Pow, partition coefficient
( Octonol /water)
0.60
UEL: 11.5 %v/v; LEL: 2.2%v/v;
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
p) Auto-ignition temperature
427°C
q) Decomposition temperature
Not available
r) Viscosity
0.44 Pas @25 °C
s) Explosive property
No
t) Oxidizing property
No
9.2. Other information.

Specific gravity(Water=1) is 0.902; Koc is 8.8; Corrosive Material= No ; Molecular weight 88.11
SECTION 10:
STABILITY AND REACTIVITY
10.1. Reactivity
a) Ethyl acetate can be hydrolyzed in acidic or basic conditions to regain acetic acid and ethanol. The use
of an acid catalyst accelerates the hydrolysis, ethyl esters are typically hydrolyzed in a two step process
starting with a stoichiometric amount of strong base, such as sodium hydroxide.
10.2. Chemical stability
b) Stable under normal temperature and pressure. Heat will contribute to instability.
10.3. Possibility of hazardous reactions
c) Hazardous Polymerization: Not reported
10.4. Conditions to avoid
d) Avoid heat, flame and other sources of ignition. Contact with nitrates, strong oxidizers, strong alkalis, or
strong acids may cause fire and explosions. Will attack some forms of plastic, rubber, and coatings.
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
10.5. Incompatible materials
e) Strong acids, strong oxidizing agents and strong bases.
10.6. Hazardous decomposition products
f) Thermal decomposition may produce carbon monoxide, carbon dioxide, acetic acid, and ethyl alcohol.
SECTION 11:
TOXICOLOGICAL INFORMATION
11.1. Information on toxicological effects
a) Acute toxicity
RTECS#: AH5425000
ACUTE ORAL LD50 (Rat)
ACUTE DERMAL LD50:(Rabbit)
ACUTE INHALATION LC50:
= 5620 mg/kg
= > 20 g/kg
= 200000mg/m3
b) Skin corrosion/irritation
Method: Rabbit (New Zealand) : Slightly irritating
Reference: Friend, DR, Phillips, SJ, Hills, JR (1991)
c) Serious eye damage/irritation
Method: Rabbit (New Zealand) :Not irritating
Reference: ECETOC, Brussels (1998)
Summary of irritation: In a briefly reported study carried out to a US Federal Register protocol, rabbits were
dermally exposed to ethyl acetate under semi-occlusive conditions for a period of 4 hours. No signs of any
irritation were observed during the 72 hour observation period after the exposure. Under the conditions of this
study, ethyl acetate was clearly not a skin irritant
Eye irritation: not irritating
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Ethyl acetate vapor is a weak sensory irritant at high concentrations. Liquid ethyl acetate is mildly irritating to
the eye and is not a skin irritant.
d) Sensitisation
Skin
Method: Guinea Pig
Result: Not sensitizing
Reference: Murmann P (1988)
Respiratory system: No data available
Summary: The skin sensitization has been evaluated in humans using patch tests, although the original
publications of these studies are not available. Ethyl acetate was tested at 10% in petrolatum on the skin of 25
volunteers. No sensitization reactions occurred.
There is no data available on respiratory sensitising properties. Ethyl acetate does not have any functional
groups or structures that are associated with respiratory sensitisation.
e) Germ cell mutagenicity
Method: bacterial reverse mutation assay (e.g. Ames test) (gene mutation) S. typhimurium TA
1535, TA 1537, TA 98 and TA 100 (met. act.: with and without)
Result: negative
Reference: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. (1992)
Summary: There is clear evidence to indicate that ethyl acetate is not mutagenic in vitro bacterial or yeast test
systems with or without metabolic activation and no evidence for mutagenicity results from in vivo assays.
f) Carcinogenicity
Method
mouse (A/He) male/female
(intraperitoneal) 150 mg/kg
bw/injection (total dose: 3600
Jubilant Life Sciences Limited
Result
Ethyl acetate did not produce an
increase in mouse lung tumours
compared with controls:
Reference
Stoner GD; Shimkin MB; Kniazeff
AJ; Weisburger JH; Weisburger
EK; Bori GB. (1973)
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Product Identification: Ethyl Acetate
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mg/kg bw) and 750
mg/kgbw/injection (total dose:
18000 mg/kg bw)
Exposure: 8 w (3 times/week)
Mouse Pulmonary Tumour Test
according to method of Andervant
Summary: The potential for ethyl acetate to induce lung tumors in a mouse pulmonary tumor model was
evaluated by Stoner (1973). A/He Mice received intraperitoneal injections of 150mg/kg or 750mg/kg three
times weekly for eight weeks. The animals were sacrificed 24 weeks after the 1st injections and the lungs
examined for lesions. Ethyl acetate did not produce an increase in mouse lung tumours compared with controls.
g) Reproductive toxicity
Method
mouse (CD-1) male/female
two-generation study oral:
drinking water 5, 10 and 15%
v/v in water (analytical conc.)
0.0 6900, 13800, and 20700
mg/kg/day. (actual ingested
(based on water consumption
values))
Exposure: Exposure period:
18 weeks Premating exposure
period (males): Parental 7
days; F1 74 days Premating
exposure period (females):
Parental 7 days; F1 74 days
(ad libitum)
Result
NOAEL (P): 20700 mg/kg
bw/day (actual dose received)
(male/female) (No effects
observed in parameters studied
at all doses. Result for ethanol.
Equivalent to 39600mg/kg/day
for ethyl acetate on a molar
basis.)
Reference
George, J., Myers, C., Reel, J.
et al. (1985)
Summary: The evidence suggests that the potential for ethyl acetate to cause fertility effects is
low. A two generation study on the surrogate substance shows no effects with oral doses up to
13800mg/kg/day for ethanol (equivalent to 26400mg/kg/day ethyl acetate). By inhalation, ethyl
acetate itself produced no effects at exposures of 6000ppm (22mg/l). Effects were reported
following acute exposures to 16000ppm ethyl acetate.
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
h) STOT-single exposure : No data available
i) STOT- repeated exposure: No data available
j) Aspiration Hazards: Not expected
11.2 Other Information
ACUTE EFFECTS

It is irritating to mucous surfaces, particularly the eyes, gums and respiratory passages. . It is moderately
toxic by intraperitoneal and subcutaneous routes. Skin exposure can lead to dry skin. Vapors may cause
drowsiness or dizziness. Not considered as dangerous to the environment.
CHRONIC EFFECTS:

After skin contact: Degreasing effect on the skin possibly followed by secondary inflammation.
After long-term exposure to the chemical: Sensitisation with allergic manifestations has been reported.

Target Organs: Eyes, skin, respiratory system, CNS, liver and blood.
SECTION 12:
ECOLOGICAL INFORMATION
12.1. Toxicity
12.1.1 Ecotoxicity:
 Aquatic LC50 (48h) Leuciscus idus melanotus (fish, fresh water) = 270-333 mg/L
 Aquatic LC50 (96h) Pimephales promelas (fish, fresh water) = 230 mg/L
 Aquatic EC50 (24h) Artemia Salina (Crustacea) = 644.8 mg/L
 Aquatic EC50 (48h) Daphnia Cucullata (Crustacea) = 164mg/L
 Aquatic EC50 (48h) Scenedesmus subspicatus (Algae) = 3300mg/L
 Aquatic EC50 (15min) Photobacterium Phosphoreum (Bacteria) = 5870mg/L
12.1.2 .Chronic Toxicity to Fish:
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Aquatic LOEC (32days) Pimephales Promelas (fish, fresh water) = 9.65mg/L
12.2. Persistence and degradability

It undergoes rapid biodegradation. Substance is biodegradable with low possibility of bioaccumulation.
12.3. Bioaccumulative potential

Log Pow =0.6. This chemical is not likely to bioconcentrate.
12.4. Mobility in soil



Koc=8.8. If released on land, Ethyl acetate will be lost by evaporation and leaching into groundwater.
Biodegradation should also occur. It is very soluble in water and is not expected to absorb significantly
to soil.
Because of its high vapor pressure and low adsorption to soil, ethyl acetate would be expected to
volatilize rapidly from soil and other surfaces.
Solubility In Water: 83g/l at 200 C. This product is lighter than water and will float on the surface. The
product is poorly absorbed onto soils or sediments.
12.5. Results of PBT and vPvB assessment

The substance does not meet the criteria for PBT or vPvB in accordance with Annex XIII.
12.6. Other adverse effects.

Henry’s Law constant: 1.5 10E-4 atm-m3/mole. From Henry’s Law constant one can calculate a half-life
for volatilization from a river 1 m deep with a 1 m /sec current and 3 m/sec wind of 10.1 hour.
Diffusions through the liquid and the vapor phase are an important element in the volatilization process
so changes in current and wind will affect the rate.
SECTION 13:
DISPOSAL CONSIDERATIONS
13.1. Waste treatment methods



US EPA Waste Number: U112 (Ignitable waste, USA)
Burn in a chemical incinerator equipped with an afterburner and scrubber.
Exert extra care in igniting, as this material is highly flammable.
Jubilant Life Sciences Limited
Page 19 of 42
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According to REG (EC) no.453/2010
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011

Dispose of this material in accordance with standard practice for disposal of potentially hazardous
materials as required by applicable federal, state or local laws. Note that disposal regulations may also
apply to empty containers and equipment rinsates.
SECTION 14:

TRANSPORT INFORMATION
This substance is considered to be hazardous for transport by Air/Rail/Road and Sea and thus regulated
by IMO/ IMDG/ IATA/ ICAO.

Mode of Transport
Land transport
Agency
Maritime Transport
ADR/RID
IMDG
Air Transport
IATA
14.1. UN number

UN 1173
14.2. UN proper shipping name

Ethyl acetate
14.3. Transport hazard class(es)


Flammable liquid class 3
Hazard Label
14.4. Packing group
 II
14.5. Environmental hazards
Jubilant Life Sciences Limited
Page 20 of 42
Safety Data Sheet
According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011

The substance is not environmentally hazardous according to the criteria of the UN Model Regulations
(As reflected in the IMDG Code, ADR, RID and ADN and/or a marine pollutant according to the IMDG
code.
14.6. Special precautions for user
SECTION 15:
REGULATORY INFORMATION
15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture.
 European/International Regulations
 European Labeling in Accordance with EC Directives
Classification (as per Regulation (EC) No 1272/2008):
 Hazards Class and Category: Flammable Liquid Cat.2, STOT single exposure Cat.3
 Hazard Statements: H225; H336
Classification as per directive 67/548/EEC
 Classification: R11 - Xi; R36 - R66 - R67
Xi
Irritant
US information








It is listed in EPA TSCA chemical inventory.
CERCLA Section 103 ((40CFR302.4): 5000 LBS RQ
None of the chemicals in this product have an TPQ under SARA Section 302 TPQ
None of the chemicals in this product are reported under SARA Section 313
None of the chemicals in this product contain any class1 & class2 ozone depletors, neither contain any
hazardous air pollutants under ‘Clean Air Act’
None of the chemicals in this product are listed as Hazardous substances or priority pollutants or Toxic
substances list under ‘Clean Water Act
NFPA Code: H1; F3; R0
Transport Emergency Card: TEC (R)-76
Jubilant Life Sciences Limited
Page 21 of 42
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--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Canada Regulatory Information
 WHMIS Classification: This product has been classified in accordance with the hazard criteria of the
CPR.
 DSL: Yes ;NDSL: No
15.2. Chemical safety assessment.
 The substance was subject to a Chemical Safety Assessment according to article 18
of the REACH regulation. Relevant chapters of the resulting Chemical Safety Report
(CSR) – exposure scenarios and risk management measures – are listed in the annex to
this safety data sheet.
SECTION 16:
OTHER INFORMATION
(a) Compilation information of safety data sheet
Change Note:
SDS data
Chemical: Ethyl acetate
CAS #: 141-78-6
File Name: 0044C02 Div.01 sds Ethyl acetate
Date of Preparation of SDS : December 16, 2010
Revision Number: 03
Revision Due Date: November, 2012
Date of Issue of SDS: June 27th, 2011
(b) A key or legend to aberrations and acronyms used in the safety data sheet;


PBT =Persistent Bioaccumulative and Toxic
vPvB= Very Persistent and Very Bioaccumulative
Jubilant Life Sciences Limited
Page 22 of 42
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According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011




























(c)



SCBA= Self Contained Breathing Apparatus
NIOSH REL= National Institute for Occupational Safety and Health Recommended Exposure
Limit
OSHA PEL=Occupational Safety and Health Adminstration Permissible Exposure Limit
OELTWA= Occupational Exposure Limit Time Weighted Averages
IDLH= Immediately Dangerous to Life or Health
UEL= Upper Explosive Limit
LEL= Lower Explosive Limit
RTECS= Registry of Toxic Effects of Chemical Substances
NTP=National Toxicology Programm
IARC= International Agency for Research on Cancer
EPA=Environmental Protection Agency
TSCA= Toxic Substances Control Act
NFPA= National Fire Protection Association
CSR=Chemical Safety Report
BCF = Bio Concentration Factor
DNEL = Derived No Effect Level
PNEC = Predicted No Effect Concentration
TLV = Threshhold Limit Value
ACGIH = American Conference of Governmental Industrial Hygienist
REACH = Registration, Evaluation .Authorisation and Restriction of Chemicals
CLP = Classification, Labelling and Packaging
LD / LC = Lethal Doses / Lethal Concentration
GHS = Globally Harmonised System
ADR = Accord europeen relative au transport international de marchandises
IMDG-Code = International Maritime Code for Dangerous Goods
EmS = Emergency measures on Sea
ICAO = International Civil Aviation Organization
IATA/DGR= International Air Transport Association/Dangerous Goods Regulation
Key Literature reference and sources for data
Hazardous Substance Data Bank
RTECS
IARC
( d) List of Risk Phrases, Hazard statements, safety Phrases.
Jubilant Life Sciences Limited
Page 23 of 42
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According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Risk Phrases
R11; R36; R66; R67
R11 : Highly flammable.
R36 : Irritating to eyes.
R66 : Repeated exposure may cause skin dryness or cracking.
R67 : Vapours may cause drowsiness and dizziness.
Safety Phrases
S16; S26 ; S33
S2 : Keep out of the reach of children.
S16 : Keep away from sources of ignition - No smoking.
S26 : In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S33 : Take precautionary measures against static discharges.
Hazards Statements
H225; H336
H225: Highly flammable liquid and vapour.
H336: May cause drowsiness or dizziness.
Company’s Declaration:
Information contained in this SDS is believed to be correct but no representation, guarantee or warranties of any
kind are made as to its accuracy, suitability for a particular application or results to be obtained from them. This
SDS shall be used as a guide only. Jubilant Life Sciences Limited makes no warranties expressed or implied of
the adequacy of this document for any particular purpose.
Jubilant Life Sciences Limited
Page 24 of 42
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According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Annex
Register of relevant Exposure Scenarios (ES) and Risk Management Measure (RMM) out of the CSR
(Chemical Safety Report). The detailed CSR can be provided on request only.
ES
Number
Exposure Scenario
Name
Sector of Use
(SU)
1)
Industrial
manufacturing of ethyl
acetate
SU 8
2)
Drumming and
distribution of Ethyl
Acetate
SU 8
SU 9
3)
Industrial formulation
of Ethyl Acetate and
its mixtures
Jubilant Life Sciences Limited
SU 10
Product
Category ( PC)
Process
Category
(PROC)
PROC 1
PROC 2
PROC 8b
Environmental
Release category
(ERC)
ERC 1
PROC 1
PROC 2
PROC 8a
PROC 8b
PROC 9
ERC 2
PROC 1
PROC 2
PROC 3
PROC 4
PROC 5
PROC 8a
PROC 8b
PROC 9
ERC 2
Page 25 of 42
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--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
4)
Industrial use as an
Extraction Solvent
and/or Processing Aid
5)
Industrial Application
of Paints, Coatings and
other Mixtures
6)
7)
SU 9
PC 9a
containing Ethyl
Acetate by way of
Spraying
Industrial Application
of Paints and Coatings
\(non-spray
application)
Industrial and
Professional (end) use
of ethyl acetate as a
laboratory reagent
PROC 3
PROC 4
PROC 8a
PROC 8b
ERC 1
PROC 1
PROC 2
PROC 7
PROC 8a
PROC 8b
ERC 4
PROC 1
PROC 2
PROC 8a
PROC 8b
PROC 10
PROC 13
ERC 4
ERC4
PROC 15
Uses by professional workers
ES
Number
Exposure Scenario
Name
Sector of Use
(SU)
1)
Professional
application f paints,
coatings, adhesives
and other
mixtures/products
containing ethyl
acetate (indoors or
outdoors, spray or non
SU 8
Jubilant Life Sciences Limited
Product
Category ( PC)
Process
Category
(PROC)
PROC 1
PROC 2
PROC 8a
PROC 8b
PROC 10
PROC 11
PROC 13
PROC 19
Environmental
Release category
(ERC)
ERC 8a
ERC 8d
Page 26 of 42
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According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
spray application)
2)
PROC 15
ERC 8a
Industrial and
Professional (end) use
of ethyl acetate as a
laboratory reagent
Uses by Consumers
ES
Number
Exposure Scenario
Name
1)
Consumer use of Ethyl
Acetate in Adhesives
and Coatings
Sector of Use
(SU)
2)
Product
Category ( PC)
PC 1
PC 9a
PC 39
Environmental
Release category
(ERC)
ERC 8a
ERC 8a
Consumer use of ethyl
acetate in cosmetic
products
2.2. Identified uses and Risk Management measures
Identified
Use (IU)
name
Use descriptors
Manufacture Process category (PROC):
PROC 1: Use in closed process, no
Jubilant Life Sciences Limited
Risk Management Measures (RMMs)
Avoid direct skin or eye contact with product. Identify
potential areas for indirect skin contact. Wear gloves
Page 27 of 42
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According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
Risk Management Measures (RMMs)
likelihood of exposure
(tested to EN374) if hand contact with substance likely.
Clean up contamination/spills as soon as they occur.
PROC 2: Use in closed, continuous Wash off any contamination immediately. Provide
process with occasional controlled basic employee training to prevent / minimise
exposure
exposures and to report any skin or eye problems that
PROC 8b: Transfer of substance or may develop [E3.1].
preparation (charging/discharging) Other protection measures such as impervious suits and
from/to vessels/large containers at face shields or goggles may be required during high
dedicated facilities
dispersion activities which are likely to lead to
Environmental release category
(ERC):
ERC 1: Manufacture of substances
Sector of end use (SU):
SU 8: Manufacture of bulk, large
scale chemicals (including
petroleum products)
Subsequent service life relevant
for that use?: no
substantial aerosol release. [E4.1]
Sample via closed loop or other system to avoid
exposure [E8]
Provide a good standard of general ventilation (not less
than 3 to 5 air changes per hour). [E11]
Ensure operation is carried out outdoors [E69],
or,Provide a good standard of general ventilation (not
less than 3 to 5 air changes per hour). [E11]
Handle substance within a closed system [E47]
Drain down and flush system prior to equipment breakin or maintenance [E55]
Ensure material transfers are under containment or
extract ventilation [E66]
Handle in a fume cupboard or under extract ventilation
[E83]
Jubilant Life Sciences Limited
Page 28 of 42
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According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
Risk Management Measures (RMMs)
Store substance within a closed system [E84]
Avoid carrying out activities involving exposure for
more than 15 minutes [OC26]
Avoid carrying out activities invloving exposure for
more than 4 hours [OC28]
Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16]
Distribution Process category (PROC):
Avoid direct skin or eye contact with product. Identify
potential areas for indirect skin contact. Wear gloves
PROC 1: Use in closed process, no (tested to EN374) if hand contact with substance likely.
likelihood of exposure
Clean up contamination/spills as soon as they occur.
PROC 2: Use in closed, continuous Wash off any contamination immediately. Provide
process with occasional controlled basic employee training to prevent / minimise
exposures and to report any skin or eye problems that
exposure
may develop [E3.1]
PROC 8a: Transfer of substance or
preparation (charging/discharging) Other protection measures such as impervious suits and
from/to vessels/large containers at face shields or goggles may be required during high
dispersion activities which are likely to lead to
non-dedicated facilities
substantial aerosol release. [E4.1]
PROC 8b: Transfer of substance or
preparation (charging/discharging) Locate bulk storage outdoors [E2] or Provide a good
from/to vessels/large containers at standard of general ventilation (not less than 3 to 5 air
changes per hour). [E11]
dedicated facilities
PROC 9: Transfer of substance or
preparation into small containers
Jubilant Life Sciences Limited
Sample via a closed loop or other system to avoid
exposure [E8]
Page 29 of 42
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According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
(dedicated filling line, including
weighing)
Environmental release category
(ERC):
Risk Management Measures (RMMs)
Ensure operation is undertaken outdoors [E69], or,
Provide a good standard of general ventilation (not less
than 3 to 5 air changes per hour). [E11]
Clear transfer lines prior to de-coupling [E39]
ERC 2: Formulation of preparations Handle substance within a closed system [E47]
Sector of end use (SU):
SU 8: Manufacture of bulk, large
scale chemicals (including
petroleum products)
Provide extract ventilation to points where emissions
occur [E54]
Drain down and flush system prior to equipment breakin or maintenance [E55]
SU 9: Manufacture of fine chemicals Ensure material transfers are under containment or
extract ventilation [E66]
Subsequent service life relevant
for that use?: no
Handle in a fume cupboard or under extract ventilation
[E83]
Store substance within a closed system [E84]
Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16]
Avoid carrying out activities involving exposure for
more than 1 hour [OC27]
Avoid carrying out activities involving exposure for
more than 4 hours [OC28]
Formulation Process category (PROC):
Jubilant Life Sciences Limited
Avoid direct skin or eye contact with product. Identify
potential areas for indirect skin contact. Wear gloves
Page 30 of 42
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According to REG (EC) no.453/2010
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
Risk Management Measures (RMMs)
PROC 1: Use in closed process, no (tested to EN374) if hand contact with substance likely.
likelihood of exposure
Clean up contamination/spills as soon as they occur.
Wash off any contamination immediately. Provide
PROC 2: Use in closed, continuous basic employee training to prevent / minimise
process with occasional controlled exposures and to report any skin or eye problems that
exposure
may develop [E3.1].
PROC 3: Use in closed batch
process (synthesis or formulation)
PROC 4: Use in batch and other
process (synthesis) where
opportunity for exposure arises
Other protection measures such as impervious suits and
face shields or goggles may be required during high
dispersion activities which are likely to lead to
substantial aerosol release. [E4.1]
Locate bulk storage outdoors [E2] or Provide a good
standard of general ventilation (not less than 3 to 5 air
changes per hour). [E11]
PROC 5: Mixing or blending in
batch processes for formulation of
preparations and articles (multistage Sample via closed loop or other system to avoid
and/or significant contact)
exposure [E8]
PROC 8a: Transfer of substance or Ensure operation is undertaken outdoors [E69], or ,
preparation (charging/discharging) Provide a good standard of general ventilation (not less
from/to vessels/large containers at than 3 to 5 air changes per hour). [E11]
non-dedicated facilities
Provide a good standard of general ventilation (not less
PROC 8b: Transfer of substance or than 3 to 5 air changes per hour). [E11]
preparation (charging/discharging)
from/to vessels/large containers at Handle substance within a closed system [E47]
dedicated facilities
Provide extract ventilation to points where emissions
PROC 9: Transfer of substance or occur [E54]
preparation into small containers
Drain down and flush system prior to equipment break(dedicated filling line, including
Jubilant Life Sciences Limited
Page 31 of 42
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According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
weighing)
Environmental release category
(ERC):
Risk Management Measures (RMMs)
in or maintenance [E55]
Ensure material transfers are under containment or
extract ventilation [E66]
ERC 2: Formulation of preparations Handle in a fume cupboard or under extract ventilation
[E83]
Sector of end use (SU):
Wear chemically resistant gloves (tested to EN374) in
SU 10: Formulation [mixing] of
combination with ‘basic’ employee training [PPE16]
preparations and/or re-packaging
(excluding alloys)
Avoid carrying out activities involving exposure for
more than 1 hour [OC27]
Subsequent service life relevant
for that use?: no
Avoid carrying out activities involving exposure for
more than 4 hours [OC28]
Use in
Process category (PROC):
Industrial use
PROC 3: Use in closed batch
as an
process (synthesis or formulation)
Extraction
Solvent
PROC 4: Use in batch and other
and/or
process (synthesis) where
Processing
opportunity for exposure arises
Aid
PROC 8a: Transfer of substance or
preparation (charging/discharging)
from/to vessels/large containers at
non-dedicated facilities
Avoid direct skin or eye contact with product. Identify
potential areas for indirect skin contact. Wear gloves
(tested to EN374) if hand contact with substance likely.
Clean up contamination/spills as soon as they occur.
Wash off any contamination immediately. Provide
basic employee training to prevent / minimise
exposures and to report any skin or eye problems that
may develop [E3.1].
Other protection measures such as impervious suits and
face shields or goggles may be required during high
dispersion activities which are likely to lead to
substantial aerosol release. [E4.1]
PROC 8b: Transfer of substance or
preparation (charging/discharging) Locate bulk storage outdoors [E2] or Provide a good
Jubilant Life Sciences Limited
Page 32 of 42
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According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
from/to vessels/large containers at
dedicated facilities
Environmental release category
(ERC):
ERC 1: Manufacture of substances
Sector of end use (SU):
SU 9: Manufacture of fine chemicals
Subsequent service life relevant
for that use?: no
Risk Management Measures (RMMs)
standard of general ventilation (not less than 3 to 5 air
changes per hour). [E11]
Sample via closed loop or other system to avoid
exposure [E8]
Ensure operation is undertaken outdoors [E69], or ,
Provide a good standard of general ventilation (not less
than 3 to 5 air changes per hour). [E11]
Provide a good standard of general ventilation (not less
than 3 to 5 air changes per hour). [E11]
Handle substance within a closed system [E47]
Provide extract ventilation to points where emissions
occur [E54]
Drain down and flush system prior to equipment breakin or maintenance [E55]
Ensure material transfers are under containment or
extract ventilation [E66]
Handle in a fume cupboard or under extract ventilation
[E83]
Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16]
Avoid carrying out activities involving exposure for
more than 1 hour [OC27]
Jubilant Life Sciences Limited
Page 33 of 42
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According to REG (EC) no.453/2010
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
Risk Management Measures (RMMs)
Avoid carrying out activities involving exposure for
more than 4 hours [OC28]
Table 2. Uses by professional workers
Identified
Use (IU)
name
Use descriptors
Industrial
Process category (PROC):
Application
PROC 1: Use in closed process, no
of Paints,
Coatings and likelihood of exposure
other
PROC 2: Use in closed, continuous
Mixtures
process with occasional controlled
containing
exposure
Ethyl Acetate
PROC 7: Industrial spraying
by way of
Spraying
PROC 8a: Transfer of substance or
preparation (charging/discharging)
from/to vessels/large containers at
non-dedicated facilities
Risk Management Measures (RMMs)
Avoid direct skin or eye contact with product. Identify
potential areas for indirect skin contact. Wear gloves
(tested to EN374) if hand contact with substance likely.
Clean up contamination/spills as soon as they occur.
Wash off any contamination immediately. Provide
basic employee training to prevent / minimise
exposures and to report any skin or eye problems that
may develop [E3.1].
Other protection measures such as impervious suits and
face shields or goggles may be required during high
dispersion activities which are likely to lead to
substantial aerosol release. [E4.1]
Locate bulk storage outdoors [E2] or Provide a good
PROC 8b: Transfer of substance or standard of general ventilation (not less than 3 to 5 air
preparation (charging/discharging)
Jubilant Life Sciences Limited
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
from/to vessels/large containers at
dedicated facilities
Market sector by type of chemical
product:
Risk Management Measures (RMMs)
changes per hour). [E11]
Sample via closed loop or other system to avoid
exposure [E8]
Ensure operation is undertaken outdoors [E69], or ,
PC 9a: Coatings and paints, thinners, Provide a good standard of general ventilation (not less
paint removes
than 3 to 5 air changes per hour). [E11]
Environmental release category
(ERC):
Provide a good standard of general ventilation (not less
than 3 to 5 air changes per hour). [E11]
ERC 4: Industrial use of processing Handle substance within a closed system [E47]
aids in processes and products, not
Provide extract ventilation to points where emissions
becoming part of articles
occur [E54]
Subsequent service life relevant for
Drain down and flush system prior to equipment breakthat use?: no
in or maintenance [E55]
Ensure material transfers are under containment or
extract ventilation [E66]
Handle in a fume cupboard or under extract ventilation
[E83]
Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16]
Avoid carrying out activities involving exposure for
more than 1 hour [OC27]
Avoid carrying out activities involving exposure for
Jubilant Life Sciences Limited
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
Risk Management Measures (RMMs)
more than 4 hours [OC28]
Industrial
Process category (PROC):
Application
of Paints and PROC 1: Use in closed process, no
likelihood of exposure
Coatings
\(non-spray
PROC 2: Use in closed, continuous
application)
process with occasional controlled
exposure
Avoid direct skin or eye contact with product. Identify
potential areas for indirect skin contact. Wear gloves
(tested to EN374) if hand contact with substance likely.
Clean up contamination/spills as soon as they occur.
Wash off any contamination immediately. Provide
basic employee training to prevent / minimise
exposures and to report any skin or eye problems that
may develop [E3.1].
PROC 8a: Transfer of substance or
preparation (charging/discharging) Other protection measures such as impervious suits and
from/to vessels/large containers at face shields or goggles may be required during high
dispersion activities which are likely to lead to
non-dedicated facilities
substantial aerosol release. [E4.1]
PROC 8b: Transfer of substance or
preparation (charging/discharging) Locate bulk storage outdoors [E2] or Provide a good
from/to vessels/large containers at standard of general ventilation (not less than 3 to 5 air
changes per hour). [E11]
dedicated facilities
PROC 10: Roller application or
brushing
Sample via closed loop or other system to avoid
exposure [E8]
PROC 13: Treatment of articles by
dipping and pouring
Ensure operation is undertaken outdoors [E69], or ,
Provide a good standard of general ventilation (not less
Jubilant Life Sciences Limited
Page 36 of 42
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Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
Risk Management Measures (RMMs)
Environmental release category
(ERC):
than 3 to 5 air changes per hour). [E11]
Provide a good standard of general ventilation (not less
ERC 4: Industrial use of processing than 3 to 5 air changes per hour). [E11]
aids in processes and products, not
Handle substance within a closed system [E47]
becoming part of articles
Provide extract ventilation to points where emissions
Subsequent service life relevant for
occur [E54]
that use?: no
Drain down and flush system prior to equipment breakin or maintenance [E55]
Ensure material transfers are under containment or
extract ventilation [E66]
Handle in a fume cupboard or under extract ventilation
[E83]
Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16]
Avoid carrying out activities involving exposure for
more than 1 hour [OC27]
Avoid carrying out activities involving exposure for
more than 4 hours [OC28]
Jubilant Life Sciences Limited
Page 37 of 42
Safety Data Sheet
According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
Risk Management Measures (RMMs)
Industrial
Process category (PROC):
Avoid direct skin or eye contact with product. Identify
and
potential areas for indirect skin contact. Wear gloves
PROC
15:
Use
as
laboratory
reagent
Professional
(tested to EN374) if hand contact with substance likely.
(end) use of Environmental release category
Clean up contamination/spills as soon as they occur.
Wash off any contamination immediately. Provide
(ERC):
basic employee training to prevent / minimise
ERC 4: Industrial use of processing exposures and to report any skin or eye problems that
aids in processes and products, not may develop [E3.1]
becoming part of articles
Other protection measures such as impervious suits and
face shields or goggles may be required during high
Subsequent service life relevant for
dispersion activities which are likely to lead to
that use?: no
substantial aerosol release. [E4.1]
Provide a good standard of general ventilation (not less
than 3 to 5 air changes per hour). [E11]
Handle in a fume cupboard or under extract ventilation
[E83]
Professional
application f
paints,
coatings,
adhesives
and other
mixtures/pro
ducts
containing
Process category (PROC):
PROC 1: Use in closed process, no
likelihood of exposure
PROC 2: Use in closed, continuous
process with occasional controlled
exposure
Avoid direct skin or eye contact with product. Identify
potential areas for indirect skin contact. Wear gloves
(tested to EN374) if hand contact with substance likely.
Clean up contamination/spills as soon as they occur.
Wash off any contamination immediately. Provide
basic employee training to prevent / minimise
exposures and to report any skin or eye problems that
may develop [E3.1].
PROC 8a: Transfer of substance or
preparation (charging/discharging) Other protection measures such as impervious suits and
Jubilant Life Sciences Limited
Page 38 of 42
Safety Data Sheet
According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
Risk Management Measures (RMMs)
ethyl acetate
(indoors or
outdoors,
spray or non
spray
application)
from/to vessels/large containers at
non-dedicated facilities
face shields or goggles may be required during high
dispersion activities which are likely to lead to
substantial aerosol release. [E4.1]
PROC 8b: Transfer of substance or
preparation (charging/discharging) Locate bulk storage outdoors [E2] or Provide a good
from/to vessels/large containers at standard of general ventilation (not less than 3 to 5 air
dedicated facilities
changes per hour). [E11]
PROC 10: Roller application or
brushing
Sample via closed loop or other system to avoid
exposure [E8]
PROC 11: Non industrial spraying
Ensure operation is undertaken outdoors [E69], or ,
Provide a good standard of general ventilation (not less
PROC 13: Treatment of articles by than 3 to 5 air changes per hour). [E11]
dipping and pouring
Provide a good standard of general ventilation (not less
PROC 19: Hand-mixing with
than 3 to 5 air changes per hour). [E11]
intimate contact and only PPE
Handle substance within a closed system [E47]
available.
Environmental release category
(ERC):
Provide extract ventilation to points where emissions
occur [E54]
ERC 8a: Wide dispersive indoor use Drain down and flush system prior to equipment breakof processing aids in open systems in or maintenance [E55]
ERC 8d: Wide dispersive outdoor
use of processing aids in open
systems
Ensure material transfers are under containment or
extract ventilation [E66]
Handle in a fume cupboard or under extract ventilation
Subsequent service life relevant for [E83]
that use?: no
Wear chemically resistant gloves (tested to EN374) in
Jubilant Life Sciences Limited
Page 39 of 42
Safety Data Sheet
According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
Risk Management Measures (RMMs)
combination with ‘basic’ employee training [PPE16]
Avoid carrying out activities involving exposure for
more than 1 hour [OC27]
Avoid carrying out activities involving exposure for
more than 4 hours [OC28]
Industrial
and
Professional
(end) use of
ethyl acetate
as a
laboratory
reagent
Process category (PROC):
Avoid direct skin or eye contact with product. Identify
potential areas for indirect skin contact. Wear gloves
PROC 15: Use as laboratory reagent (tested to EN374) if hand contact with substance likely.
Clean up contamination/spills as soon as they occur.
Environmental release category
Wash off any contamination immediately. Provide
(ERC):
basic employee training to prevent / minimise
ERC 8a: Wide dispersive indoor use exposures and to report any skin or eye problems that
of processing aids in open systems may develop [E3.1]
Other protection measures such as impervious suits and
Subsequent service life relevant for
face shields or goggles may be required during high
that use?: no
dispersion activities which are likely to lead to
substantial aerosol release. [E4.1]
Provide a good standard of general ventilation (not less
than 3 to 5 air changes per hour). [E11]
Handle in a fume cupboard or under extract ventilation
[E83]
Jubilant Life Sciences Limited
Page 40 of 42
Safety Data Sheet
According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
Risk Management Measures (RMMs)
Consumer
use of Ethyl
Acetate in
Adhesives
and Coatings
Chemical product category (PC):
Avoid direct skin or eye contact with product. Identify
potential areas for indirect skin contact. Wear gloves
(tested to EN374) if hand contact with substance likely.
Clean up contamination/spills as soon as they occur.
Wash off any contamination immediately. Provide
basic employee training to prevent / minimise
exposures and to report any skin or eye problems that
may develop [E3.1].
PC 1: Adhesives, sealants
PC 9a: Coatings and paints,
thinners, paint removes
Environmental release category
(ERC):
ERC 8a: Wide dispersive indoor use Other protection measures such as impervious suits and
of processing aids in open systems face shields or goggles may be required during high
dispersion activities which are likely to lead to
Subsequent service life relevant for
substantial aerosol release. [E4.1]
that use?: no
Locate bulk storage outdoors [E2] or Provide a good
standard of general ventilation (not less than 3 to 5 air
changes per hour). [E11]
Sample via closed loop or other system to avoid
exposure [E8]
Ensure operation is undertaken outdoors [E69], or ,
Provide a good standard of general ventilation (not less
than 3 to 5 air changes per hour). [E11]
Provide a good standard of general ventilation (not less
than 3 to 5 air changes per hour). [E11]
Handle substance within a closed system [E47]
Jubilant Life Sciences Limited
Page 41 of 42
Safety Data Sheet
According to REG (EC) no.453/2010
--------------------------------------------------------------------------------------------------------------------------------------
Product Identification: Ethyl Acetate
0044D01 Div 01 sds Ethyl Acetate
Date of issue: 27th June, 2011
Identified
Use (IU)
name
Use descriptors
Risk Management Measures (RMMs)
Provide extract ventilation to points where emissions
occur [E54]
Drain down and flush system prior to equipment breakin or maintenance [E55]
Ensure material transfers are under containment or
extract ventilation [E66]
Handle in a fume cupboard or under extract ventilation
[E83]
Wear chemically resistant gloves (tested to EN374) in
combination with ‘basic’ employee training [PPE16]
Avoid carrying out activities involving exposure for
more than 1 hour [OC27]
Avoid carrying out activities involving exposure for
more than 4 hours [OC28]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
Jubilant Life Sciences Limited
Page 42 of 42