Central Dogma and Proteins
Reading Assignments
Key Ideas:
The information on DNA is processed and used.
Proteins are products and can be manufactured
Topic/Reading
Assignment #
Pages to be Read and Take
Notes On
Do Section Review
Assignment 1
Assignment 2
Assignment 3
99-112
112-121
4.1 and 4.2
4.3 and 4.4
p. 124 Thinking like..
#1,2,3,7,9
Assignment 4
Assignment 5
354-361
343-348, 370-374
13-3, 13.4
13.1, 14.1
Assignment 6
Assignment 7
Assignment 8
52-55
138-143, 377-76
131-138
2.3 #2-3
5.2
5.1
Assignment 9
Assignment 10
Assignment 11
189-201
242-254
143-150
7.1,7.2,7.3,7.4
9.3
5.3, 5.4
Assignment 12
Assignment 13
Assignment 14
STANDARD 04
150-153
377-385
386-389
5.5
14.3
14.4
17% - 12 Questions
Students will describe the properties of atoms and molecules and prepare lab reagents.
OBJECTIVES
04.02 Distinguish between covalent, ionic and hydrogen bonds.
04.03 Describe the characteristics o f bio molecules. (i.e., hydrophobic vs. h ydrophilic, acidic vs. basic, polar vs. non
polar)
04.05 Relate pH to solution preparation.
• Theory – explain acid base chemistry, pH scale and bu f f er properties.
• Method – measure and adjust the pH o f speci fic solutions with commonly used acids and bases.
04.06 Relate dilution to solution preparation.
• Theory - explain spectrophotometry and dilution principles.
• Method - prepare serial dilutions o f specific solutions.
STANDARD 07
34% - 24 Questions
Students will compare and contrast different types of macromolecules and illustrate the flow of genetic
information within the cell using the central dogma of molecular biology.
07.02 Describe the structure and function o f proteins.
• Theory - describe the four levels o f protein structure.
• Theory - explain the relationship between the structure and function o f proteins.
• Theory - identi f y functional classes of proteins. (i.e., structural, regulatory, enzymes, transport)
• Application - illustrate the primary, secondary, tertiary, and quaternary protein structure.
• Application - discuss ways proteins are used in biotechnology.
• Method - use computer resources to visualize the three dimensional structure o f proteins. (protein data bank, Hutch
lab, RasMol)
• Method – demonstrate the ability to use proper separation techniques to
differentiate between proteins based on size and structure (chromatography
and SDS-PAGE).
• Method - explore the e f fects o f environment on the function of enzymes. (i.e., temperature, ph, salt concentration)
07.04 Describe protein s ynthesis.
• Theory - identi f y the major components, outline the process and describe the products
o f transcription.
• Theory - distinguish between transcription in prokaryotic and eukaryotic s ystems.
• Theory - identi f y the major components, outline the process and describe the product
o f translation.
• Application - describe the uses o f recombinant proteins in biotechnology. (e.g., medicine, agriculture, etc.)
• Application - explain the relevance of transcription to contemporary technologies such as cDNA libraries, diagnostics
and therapies.
• Method - manipulate the production o f recombinant protein in bacteria. (e.g., GFP)