AV
A
AV
(0, 50, 0)
AV
(0, 50, 0)
Ĥfull
Ĥred
(25, 25, 0)
(0, 25, 25)
AV
(0, 50, 0)
(0, 50, 0)
̃
(25, 25, 0)
(0, 25, 25)
̃ BLUE
(25, 25, 0)
3.15×10-5
3.35×10-5
(25, 25, 0)
(0, 25, 25)
(0, 25, 25)
3.55×10-5
3.75×10-5
3.95×10-5
4.15×10-5
4.35×10-5
4.55×10-5
PO
(25, 0, 25)
(50, 0, 0)
FS
(0, 0, 50)
PO
(25, 0, 25)
(50, 0, 0)
MF
B
FS
(0, 0, 50)
PO
(25, 0, 25)
(50, 0, 0)
MF
(0, 50, 0)
(0, 25, 25)
(0, 25, 25)
FS
(0, 0, 50)
MF
(0, 50, 0)
̃ BLUE
̃
(25, 25, 0)
(25, 0, 25)
(0, 50, 0)
Ĥred
(25, 25, 0)
PO
(50, 0, 0)
MF
(0, 50, 0)
Ĥfull
FS
(0, 0, 50)
(25, 25, 0)
(0, 25, 25)
4.76×10-5
5.38×10-5
(25, 25, 0)
(0, 25, 25)
6.00×10-5
6.61×10-5
7.23×10-5
7.85×10-5
8.46×10-5
9.08×10-5
MM
(25, 0, 25)
(50, 0, 0)
FF
(0, 0, 50)
MM
(25, 0, 25)
(50, 0, 0)
AV
C
FF
(0, 0, 50)
MM
AV
(0, 50, 0)
MM
(0, 25, 25)
FF
(0, 0, 50)
AV
(0, 50, 0)
̃ BLUE
̃
(25, 25, 0)
(25, 0, 25)
(50, 0, 0)
(0, 50, 0)
Ĥred
(0, 25, 25)
FF
(0, 0, 50)
AV
(0, 50, 0)
Ĥfull
(25, 25, 0)
(25, 0, 25)
(50, 0, 0)
(25, 25, 0)
(0, 25, 25)
3.38×10-5
3.82×10-5
(25, 25, 0)
(0, 25, 25)
4.26×10-5
4.70×10-5
5.14×10-5
5.57×10-5
6.01×10-5
6.45×10-5
FSi
(50, 0, 0)
(25, 0, 25)
FSo
(0, 0, 50)
FSi
(50, 0, 0)
(25, 0, 25)
FSo
(0, 0, 50)
FSi
(50, 0, 0)
(25, 0, 25)
FSo
(0, 0, 50)
FSi
(50, 0, 0)
(25, 0, 25)
FSo
(0, 0, 50)
b full , H
b red , H,
e and H
e BLUE for samples fixed at
Figure S4: Theoretical mean squared error of H
100 (A) diploid individuals, (B) male and female individuals at an X-linked locus, or (C) diploid
individuals wherein some full siblings are inbred with brother-sister parents, across changing sample
configurations. The samples were modeled on the D3S2427 locus and contained 50 relative pairs:
(A) parent-offspring (PO), second-degree avuncular (AV), and full-sibling (FS), (B) male-male
(MM), male-female (MF), and female-female (FF) full-sibling, or (C) inbred full-sibling (FSi),
second-degree avuncular (AV), and outbred full-sibling (FSo), such that each individual was
related to exactly one other. The vertices of the heat map represent samples composed of only
one relative pair type while the space between them corresponds to all possible combinations of
relative pair types. Blue and black points indicate the smallest and largest values on the map,
respectively. Threshold values for coloration are indicated in the scales to the right of the figure,
with smaller values colored lighter.
4