The Chemistry of Life • The FIVE primary elements of Life and all Living things(You must know these symbols and the corresponding names) • C carbon • H hydrogen • O oxygen • N nitrogen • P phosphorus • When elements are combined to make molecules and compounds, the subscript number represents how many atoms of each element is in the molecule. • For example, water H2O is really 2 hydrogen and 1 oxygen atoms. • are those that contain both carbon (C) and hydrogen (H) and usually other atoms. C6H12O6 and methane, CH4. Like glucose, •We are investigating organic Macromolecules- BIG compounds • are those that DO NOT contain both carbon (C) and hydrogen (H). Like water H2O and carbon dioxide CO2 . • O2 OXYGEN • CO2 CARBON DIOXIDE • H2O WATER Processes we have seen these in: • photosynthesis • Cellular respiration • Carbon, water, & oxygen cycles • Greenhouse gases (CO2 & H2O) O2 C6H12O6 CO2 C8H18 • Water covers most of the planet (74% fresh and salt) and makes up the greatest percentage of ALL living organisms. • Depending on temperature and volume, humans can live WITHOUT WATER for only one to ten days H2 O An important property of the water molecule is that it is POLARMeaning it has an uneven distribution of charges, a slightly positive end and a slightly negative end. NONPOLAR molecules have an even distribution of charges like petroleum The slightly positive and negative ends of the water molecule allow it to act like a magnet (having positive and negative ends or poles), so that it can interact with and dissolve many other polar substances. As consequence, water is known as the universal solvent. are formed between polar molecules involving slightly positive Hydrogen and slightly negative Oxygen or Nitrogen atoms. Hydrogen bonds DO NOT change the molecules involved, these bonds are weak and temporary yet are essential in ALL living organisms. Adhesion-is the property where different molecules are attracted to each other. Look at the drop of water hanging off of the leaf in the picture…do you think that water has adhesive properties? Explain? Looking at the pictures of water on a penny, can you tell if water is adhering to the penny? What would adding soap to the number of drops you fit on the penny? Soap decreases the ability of water to form Hydrogen bonds. Cohesion-is the property where the same type of molecules are attracted to each other. Try it! Place a couple drops of water on the piece of wax paper (very hydrophobic) Push the drops around and see what happens when they come together Why does this occur? Surface tension is cohesion at the surface of a liquid due to hydrogen bonds between molecules at the surface. This forms a strong surface "film”. This is why some animals can “walk on water” and why very heavy boats float! Capillary Action is where the properties of water, adhesion and cohesion, work to draw liquids against gravity. Plants depend this property of water to get water from their roots to their leaves. Water is called the universal solvent because of all the properties it has…polarity, cohesion, and adhesion and its ability to form hydrogen bonds. A solution is a uniform mixture of at least two substances, like salt and water salt water -SOLVENT = water (does the dissolving) -SOLUTE = salt (is what is being dissolved) Like dissolves like means that the chemical properties are similar enough that if placed together they would uniformly mix, making a solution. Oil and water do not mix (for long) because one is very polar and the other is very nonpolar. Because water is so important there are two more important watery terms you need to knowHydrophilic –water loving molecules, will easily dissolve in water Hydrophobic -water fearing molecules, do not mix/dissolve in water and often move AWAY from water C, carbon, H, hydrogen, O, oxygen, N, nitrogen, and P, phosphorus ALL organic compounds MUST contain both carbon and hydrogen Glucose, C6H12O6 and methane CH4 two common organic molecules Macro=BIG A monomer is a simple compound that can join together to for polymers A polymer is a large molecule (macromolecule) composed of repeating structural units connected by covalent chemical bonds • O2 OXYGEN • CO2 CARBON DIOXIDE • H2O WATER Processes we have seen these in: • photosynthesis • Cellular respiration • Carbon, water, & oxygen cycles • Greenhouse gases (CO2 & H2O) Remember Macro mean BIG, sooooo…these are mostly very big molecules, they are as follows: 1. Carbohydrates 2. Lipids 3. Nucleic Acids 4. Proteins Are also called sugars Are made up of the elements C H O Usually, 2H for every 1 C there are 1 C to 2 H The monomers of carbohydrates are called monosaccharides Like glucose, fructose & ribose The polymers of carbohydrates are called polysaccharides Like cellulose Most & starch carbohydrates have the ENDING OSE… Cell walls (structure) Cell markers (communication) Quick Energy (Like Glucose) Stored Energy (Like Glycogen) 4 kcal (dietary calories) per gram Foods include bread, pasta, veggies and fruit 3 types: Monosaccharides Disaccharides Polysaccharides Glucose Fructose Ribose Deoxyribose Galactose -Saccharide means sugar sucrose + lactose maltose Remember many carbs end in the suffix -ose Starch Glycogen Cellulose Amylose Formation of glycosidic bonds Dehydration synthesis (AKA condensation reaction)- is the building or SYNTHESIS of macromolecules with the LOSS of a water molecule for every bond built. Hydrolysis-is the breaking down of molecules through the use of water. For every bond broken, one water molecule is used. Lysis = break http://nhscience.lonestar.edu/biol/de hydrat/dehydrat.html A reagent is a chemical compound used for detecting or identifying other substances We can test for two types of carbohydrates Monosaccharides and polysaccharides Are made up of the elements C H O Important lipids, Diglycerides and triglycerides are made up of subunits called glycerol (1) and fatty acids ( 2 or 3) Most lipids are not made of subunits or monomers Are important to all organisms for as the main part of ALL cell membranes Are used as a source of stored energy Are important insulators to help cushion, keep warm and conduct impulses 9 kcal (dietary calories) per gram Lipids include wax, oil, cholesterol and animal fat & many hormones This triglyceride is formed by building ester bonds between the fatty acids and the glycerol molecule – through dehydration synthesis Saturated fats/lipids contain only single bonds between carbons Unsaturated fats/lipids have some double bonds and fewer hydrogens (at least one “mono-unsaturated”) Fatty acids phospholipid Steroids ( lipid hormones) Carbons arranged into 4 ring structure Most lipids are extremely HYDROPHOBIC also known as nonpolar! Meaning water fearing and do not mix are insoluble in water Made up of the elements C HONP The polymers are DNA (deoxyribonucleic acid) and RNA (ribonucleic acid) which includes messenger RNA, ribosomal RNA and transfer RNA Nucleic acids function to store genetic information, DNA, (directions for making proteins) or actually direct the building of proteins, RNA. The monomers are nucleotides The three parts of the monomer are a nitrogen base, phosphate group and a pentose sugar Monomers (Nucleotides) 4 for DNA 4 for RNA Made up mostly of C, H , O and N CHON Function in movement because they make up muscle and connective tissue Are important to all organisms for structure and shape Necessary for all metabolic processesENZYMES Important role in immune system – antibodies Our proteins determine who and what we are! Monomers are amino acids There are 20 different amino acids A protein’s shape is determined by the arrangement of amino acids DNA is the instructions for making proteins in organisms, soooooooooooooooooooooo a mutation means that the protein may not work! Small proteins are often called polypeptides the amino acids that make up a protein are linked together with covalent bonds called peptide bonds 4 kcal (dietary calories) per gram Foods include egg whites, meat, and fish plants contain limited amounts of protein -Hemolglobin (in RBC) -Keratin (in hair) neg pos Enzymes regulate and maintain metabolic functions in ALL living things. They are essential to life Enzymes often end in -ase 1. 2. 3. 4. 5. THEY ARE ALL PROTEINS They speed up reactions by lowering the energy of activation (energy needed to start reaction) they are specific (only one substrate) they are reusable (used over and over) They are organic catalysts The substrate is the specific thing an enzyme works on Often are described as lock and key because how very specific they are and how they can be reused like a lock Necessary for LIFE Often end in –ase More coming soon All proteins are sensitive to change in temperature and pH If a protein changes shape, it is considered denatured and will not work properly The active site is where the substrate fits into the enzymes The reactant is what is being changed the product is what is produced after the reaction Reactants –> Products (reaction) Proteins, so of course, enzymes are very sensitive to any thing that can change their shape, denature them. Temperature and pH can DENATURE proteins so they do not work. Genetic defects, changes in DNA, can produce proteins that do not work. http://www.lewport.com/10712041113402793/lib/1071204111340 2793/Animations/Enzyme_activity.html The pH Scale is used to determine the acidity and alkalinity (base) pH Scale ranges from 0 to 14 pH is the concentration of H ions Acid = pH below 7, The lower the pH, the stronger the acid as pH approaches 0 Neutral = pH of 7pure water Base = pH above 7 (alkaline), the stronger the base is as pH approaches 14
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