Describe how homeostatic control systems in species of microbes, plants and animals support common ancestry. All “Homeostatic Control Systems” have THREE things in common: A. Receptor B. Control Center C. Effector Microbe: Food is obtained, Waste is excreted (semi-permeable Membrane… Nucleus, Food Vacuoles) From the web: Homeostasis is just a big word for balance. The mammal uses the heat it generates to keep itself in balance and able to run. The reptile has to get that heat from the environment so the mammal has to eat at least twice a day and the reptile can go with a meal only once a day. It needs to burn less energy just to stay alive. If a snake eats a big meal then it can afford to bask in the sun and wait a long time before it has to do anything except breathe and digest. Plants control themselves with water; buy cooling with respiration and by going dormant when it gets too cold. Evergreens are the few plants that don't do that. They keep going year round; usually because they live in cold climates. Osmosis is how plants pump water and nutrients around. It can release energy, and can be made to do work, as when a growing tree-root splits a stone. So a plant uses water and osmosis to help keep it in homeostasis. Mammals use insulin to regulate the amount of glucose they have in their blood and they burn glucose for energy (to create ATP). Plants use glucose as well and make it through photosynthesis and they continue to grow as long as they get sunshine and the CO2, nitrogen and other things they need for life. Most plants lose their leaves in winter so that they can remain in homeostasis with the reduced temperatures and sunshine. They sacrifice part of themselves to survive. Cactus leaves have changed into thorns so they don't lose much water through them and they rely on the chlorophyll in the main body to conduct photosynthesis to make the sugar and burn it to make the ATP they need to live. There sacrifice to homeostasis is to give up the leaf, and they can't use it to rotate to catch sunlight. The sacrifice gives them extra protection though and conserves water by reducing body expose so it is worth it. An annual plant doesn't worry about homeostasis too much it just dies each year. Perennials are plants that live more than two years and they need to worry about homeostasis. Plants do whatever they need to do to remain in homeostasis, they are willing to sacrifice part of themselves, they go dormant or even just die off to remain in homeostasis, if they die then they can't keep it up and so just quit, often they fall back to just the root system to re-sprout when conditions are right next year. There is no one system they use, but several that they use them to remain in balance with life. Animals do the same, and how much energy you spend maintaining homeostasis determines how you live. The tiny shrew lives a very fast life and has to eat its own weight in food each day because to stay in balance it needs to. Plants don't move much they generate energy from sunlight, water, and CO2; which becomes ATP the energy currency of life. They don't have to have as complex a system to remain in balance and where we use a heart and a bloodstream the plant can use osmosis to pump its water and nutrients around. It takes less energy for a plant to remain in balance. An advantage of homeostatic regulation is that it allows an organism to function effectively in a broad range of environmental conditions. For example, ectotherms tend to become sluggish at low temperatures, whereas a colocated endotherm may be fully active. That thermal stability comes at a price since an automatic regulation system requires additional energy. One reason snakes may eat only once a week is that they use much less energy to maintain homeostasis." ATP is the "molecular currency" of intracellular energy transfer. In this role, ATP transports chemical energy within cells for metabolism. It is produced as an energy source during the processes of photosynthesis and cellular respiration and consumed by many enzymes and a multitude of cellular processes including biosynthetic reactions, motility and cell division. In signal transduction pathways, ATP is used as a substrate by kinases that phosphorylate proteins and lipids, as well as by adenylate cyclase, which uses ATP to produce the second messenger molecule cyclic AMP." Plants make ATP in the Krebs cycle, via photosynthesis. They can move their leaves to catch the sun, but otherwise they don't move very much. A Venus Fly trap adds animals to its diet because it specializes in living in poor soil so it needs the extra nutrients. Plants use xylem as just one more method to remain in homeostasis, buy helping the process of osmosis All of this is done to make the energy of life and to maintain the balance for life. Explain how conditions where signal transduction is blocked or defective can be deleterious, preventative or prophylactic. (Hypertension, Diabetes, Heart Disease) Signal Transduction has two processes: A. A signaling molecule activates a specific receptor protein on the cell membrane. B. A second messenger transmits the signal into the cell, eliciting a physiological response. With multicellular organisms, numerous processes are required for coordinating individual cells to support the organism as a whole; the complexities of these processes tend to increase with the complexity of the organism. Sensing of environments at the cellular level relies on signal transduction. Signal transduction refers to any process by which a cell converts one kind of signal or stimulus into another. These processes most often involve ordered sequences of biochemical reactions inside the cell, which are carried out by enzymes, activated by second messengers resulting in what is known as a "signal transduction pathway". Signal transduction is usually rapid, lasting milliseconds in the case of ion flux, minutes for the activation of protein and lipid mediated kinase cascades, or hours and days in terms of gene expression. In single-cell organisms, signal transduction pathways determine how the cell senses and responds to its environment. In multicellular organisms, a multitude of different signal transduction pathways are required for coordinating the behavior of individual cells to support the function of the organism as a whole. As may be expected, the more complex the organism, the more complex the repertoire and interconnectivity of signal transduction pathways. Thus, sensing of both the external and internal environment at the cellular level relies on signal transduction. Many diseases such as diabetes, heart disease, inflammation and cancer arise from defects in signal transduction pathways, underscoring the critical importance of signal transduction in medicine as well as biology. Diabetes: When insulin binds on the cellular insulin receptor, it leads to a cascade of cellular processes that promote the usage or, in some cases, the storage of glucose in the cell. The effects of insulin vary depending on the tissue involved, e.g., insulin is most important in the uptake of glucose by muscle and adipose tissue. The insulin signal transduction pathway is composed of trigger mechanisms that serve as signals throughout the cell. There is also a counter mechanism in the body to stop the secretion of insulin beyond a certain limit. Namely, those counter-regulatory mechanisms are glucagon and epinephrine. Heart Disease: If the signals received to initiate the complex process of heart muscle contraction are weak or not timed properly the resulting release of glucose to power the heart muscle may not be sufficient to sustain normal heart function. Muscle contractions may be either weak or not timed properly to co-ordinate with other heart muscles. In some cases there may be a lack of sufficient amount of a particular enzyme which may result in the signal transduction pathway within the cell to function improperly. Normal heart function is a very complex process involving a great number of steps which all must take place in proper sequence. Hypertension: Signal transduction is important for contraction and relaxation of smooth muscle. Defective signal transduction could lead to chronic hypertension. With regards to transport systems, explain how within multicellular organisms, specialization of organs contributes to the overall functioning of the organism: Organ Structure Relates to function how? Heart Muscular, with multiple chambers Arteries Muscular, durable Deliver oxygen-rich blood to all of the tissues Deliver oxygen-poor blood to the respiratory structures Keep oxygen-rich blood and oxygen-poor blood separate Allow for endothermy Handles the high pressures well Stretches and recoils when heart contracts and relaxes Substances stay in the blood Veins One-way valves Capillaries One-cell thick Prevents backflow of blood Continues the closed circuit Allows for diffusion of nutrients and gases Allows for diffusion of waste products Short diffusion distance High surface area (total)
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