BIOCHEMISTRY NOTES Pre AP I. Chemistry—study of what ________________ are made of and how they ________________________ (text pages 35 – 43) A. Atom – fundamental unit of matter 1. Subatomic particles: no = neutron p+ = proton e- = electron B. Element - each different kind of atom is a different element 1. Examples: C = ___________ H = ____________ O = _______________ N = _____________ C. Compound - two or more elements chemically combined in definite proportions 1. Examples: __________ _________ _________ __________ 2. _________ - types of compounds made of nonmetals only isomers – same molecular formula; different structural formula D. Chemical reactions – process leading to _____________________________ 2 H2 + O2 2 H2O (reactants) (products) E. Compounds are classified into two broad groups: 1. _______________ Compounds – come from _______________ substances ( in = not organic = living) 2. _______________ Compounds – come from _______________ substances II. Biochemistry – chemistry of living organisms (text pages 44 – 53) A. Organic compounds – compounds made by cells and containing carbon 1. Example: ___________________________________ 2. Exception: __________________________________ 3. Organic compounds in living cells are usually complex compounds that are so large they are called ___________________________ (giant molecules) or ______________________ 4. ____________________________ are formed by process called polymerization – smaller units called ______________ join together to form __________________ 5. Four groups of organic compounds: Draw picture to remember: a. ______________________________ b. ______________________________ c. ______________________________ d. ______________________________ III. Carbohydrates A. Provides energy for all organisms — __________________________________________________ B. Most carbohydrates are manufactured _____________ by photosynthesis. C. Structure: contains the elements C, H, and O usually in ratio of 1:2:1 EXAMPLE: C6H12O6 = 6 C + 12 H + 6 O = 1 : 2 : 1 ratio of atoms GLUCOSE D. Food Sources: Fruits, Vegetables, Grains, Pasta, Rice, Sugar, Cookies, Cakes, etc… 1 E. Three groups of carbohydrates: 1. ______________________________ = single sugar; basic structural unit from which larger carbohydrates are built (mono = one sacchar = sugar) Examples: sugars usually end in -ose a. glucose – _________ - most common sugar, _______________ – produced by green plants b. fructose -- __________ - sugar in fruits c. galactose -- ___________ - sugar in milk *Reminder - These are isomers; same molecular formula, different structural formula 2. ___________________________ – double sugar (di = two) a. sucrose - cane sugar ___________________________ b. chemical reaction: 2 monosaccharides joined together to make a _____________________ glucose + fructose sucrose + water C6H12O6 + C6H12O6 C12H22O11 + H2O When water is released in a chemical reaction = dehydration synthesis Sucrose 3. ____________________________ – many sugars (poly = many) Examples: a. starch – polysaccharide stored in plants _________________________________________________________ b. glycogen –polysaccharide stored in animals – ____________________________________ c. cellulose – polysaccharide that gives support and structure to plant cells ________________ most abundant organic chemical on earth Starch What is the purpose of storing sugars as polysaccharides in plant and animal tissues? Take 5 – Complete concept map for Carbohydrates 2 IV. Monomers/Polymers 1. General term for any smaller compounds that can be joined together to make larger compounds -_____________________ example: ___________________________________ of a carbohydrate. -many glucose molecules can be joined together by dehydration synthesis to make a polysaccharide (carbohydrate) 2. General term for any large compound formed by combining monomers -- ____________________ example: Starch, Glycogen, Cellulose = _____________ -These molecules are polymers made when many glucose molecules chemically combine. Everyday Example: Monomer Polymer V. Proteins (also called peptides or polypeptides) A. Needed for ________________________________________________________ of living materials 1. cell membrane, skin, nails, hair, bones and muscles made of protein B. Fight disease – _______________________ made of proteins C. Control rate of chemical reactions in cells – __________________ made of proteins D. Food source – ___________________________________________________________________ E. Structure: 1. proteins are polymers of molecules called ___________________________ monomer = _______________________ polymer = _____________________ 2. contain the elements C, H, O and N Dehydration Synthesis of Proteins F. ____ different _______________ combine in different ways to make up thousands of different proteins G. Examples of protein structures: Take 5 – Complete concept map for Proteins 3 VI. Enzymes A. Enzymes are ________________________ in living organisms catalyst – substance that speeds up a chemical reaction B. Most enzymes are made of _____________________ C. Enzymes are _______________________ in a reaction and can be reused D. Enzymes are __________________ – speed up only one type of chemical reaction E. Lock and Key hypothesis – an explanation of how an enzyme works F. ____________________ – substance upon which a certain enzyme acts G. Naming enzymes – add “ase” to substrate name a. maltose is substrate – ________________ is enzyme b. protein is substrate – ________________ is enzyme H. One important function of enzymes is speeding up _____________________________________ I. Enzyme Diagram: *Note: Anabolic – to build Catabolic – to break down The _____________ gets used up, but the ________________ can be used again indefinitely Take 5 – Complete concept map for Enzymes under the Protein Biomolecule VII. Lipids A. Functions: 1. energy storage – __________________________________________________________ 2. makes up part of the cell membrane 3. hormones are lipids – ______________________________________________________ B. Examples: 1. Fats – ____________ at room temperature – butter, lard (animal fat) 2. Oils – ____________ at room temperature – corn oil, olive oil (plant fats) 3. Phospholipids and cholesterol – makes up ___________________________________ 4. Steroids – type of hormone that can cross cell membrane directly into cells (anabolic steroids – handout) 5. Waxes – ____________________________________________________________________ 4 C. Structure: fats and oils 1. Composed of glycerol and 3 fatty acids 2. Contain the elements C, H and O When glycerol + fatty acids combine to form 1 fat molecule, H2O is released = dehydration synthesis D. Dietary importance 1. _______________________ fats – generally come from animal fats a. Bad for you – deposited in arteries – _____________________________________________ Saturated with hydrogens (H) No double bonds in fatty acid chain 2. ________________________ fats – generally from plant oils a. Better for you Have one or more double bonds in fatty acid chain 3. Cholesterol – 2 sources a. your body produces it – essential to life: helps produce certain hormones and part of cell membranes in animals b. you consume it in food 1. bad cholesterol – _______ (low density lipoprotein) – goes to cells, excess deposited in arteries 2. good cholesterol – _______ (high density lipoprotein) – gets rid of excess LDL’s in arteries Take 5 – Complete concept map for Lipids 5 VIII. Nucleic Acids A. Function is to store and transmit ____________________________________ from parent to offspring B. Examples: ______________________________ C. Contains the elements: C, H, O, N, P D. Nucleic acids are made from monomers called ____________. The 3 components of a nucleotide are 1. 5 – carbon sugar (Deoxyribose or Ribose) 2. Phosphate Group 3. Nitrogenous Base E. Food source: All living food sources contain nucleic acids. Food sources high in nucleic acids include items such as fish, fruits, nuts, algae, and mushrooms. Take 5 – Complete concept map for Nucleic Acids 6 Function: Carbohydrates Examples: 3 groups: Structure: Elements: Dietary Examples: Draw: Monomer: Polymer: 7 Function: Enzymes: Function: Diagram: Protein Examples: Structure: Elements: Monomer: Dietary Examples: Polymer: Draw: 8 Function: Lipids Structure: Elements: Draw: Examples: Glycerol 9 3 Fatty Acids Function: Nucleic Acids Examples: Structure: 10
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