Material Safety Data Sheet
Picric Acid – Acetone
POCD
SCIENTIFIC
MATERIAL SAFETY DATA SHEET
Section 1: IDENTIFICATION
PICRIC ACID – ACETONE
Synonyms – Picrate in Acetone.
Product Code – PICACE/250ML
Recommended use – Laboratory reagent.
Point of Care Diagnostics t/a POCD Scientific
ABN: 93 067 939 824
Unit 14/76 Reserve Rd
Artarmon NSW 2064
1800 640 075 | 02 9437 1399
Australian Emergency Services: 000 (24 hours) Australian
Poisons Information Centre: 131 126 (24 hours)
Section 2: HAZARDS IDENTIFICATION
Classified as a Hazardous substance according to criteria of NOHSC.
Classified as a Dangerous good according to the ADG Code for the Transport of Dangerous Goods by Road and
Rail.
R Phrases
S Phrases
R11 – Highly flammable.
R36 – Irritating to eyes.
R66 – Repeated exposure may cause skin dryness and cracking.
R67 – Vapours may cause drowsiness and dizziness.
S1/2 – Keep locked up and out of reach of children.
S9 – Keep container in a well-ventilated place.
S16 – Keep away from sources of ignition – No smoking.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical
advice.
S45 – In case of accident or if you feel unwell, contact a Doctor or Poisons Information Centre
immediately and show this container or label.
Section 3: COMPOSITION INFORMATION
Chemical Name
Acetone
2,4,6-Trinitrophenol (Picric Acid)
CAS Number
67-64-1
88-89-1
Concentration
>97%
<3%
Section 4: FIRST AID MEASURES
Eye contact
Skin contact
Inhalation
Date of issue: August 2011
Flush eyes with copious amounts of water for at least 15 minutes. Seek medical
attention.
Remove contaminated clothing and wash affected area with soap and water
thoroughly. If irritation develops, seek medical attention.
Remove patient to fresh air. If breathing stops, apply artificial respiration and seek
medical attention.
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Material Safety Data Sheet
Ingestion
First aid facilities
Advice to Doctor
Picric Acid – Acetone
DO NOT induce vomiting. Wash mouth out with copious amounts of water. Seek
medical attention.
Eye wash station, safety shower and First Aid kit.
Treat symptomatically.
Section 5: FIREFIGHTING MEASURES
Suitable extinguishing media
Hazards for combustion products
Special protective precautions and
equipment for fire fighters
Hazchem code
Dry chemical, Carbon Dioxide or alcohol-resistant foam.
Vapours are heavier than air and may travel to an ignition source and
flash back. Vapours can spread along the ground and collect in low or
confined areas. During a fire, irritating and highly toxic gases may
evolve by thermal decomposition or combustion.
Fire fighters should wear a positive-pressure Self-Contained Breathing
Apparatus (SCBA) and protective clothing (includes helmet, coat,
trousers, boots and gloves). Clear fire area of all non-emergency
personnel. Stay upwind. Keep out of low areas where gases or fumes
can accumulate. Do not use direct water stream. Eliminate ignition
sources.
2[Y]E
Section 6: ACCIDENTAL RELEASE MEASURES
Emergency procedures
Wear full protective clothing. Evacuate all unnecessary personnel. Eliminate all
sources of ignition. Increase ventilation. Avoid walking through spilled product
as it may be slippery. Stop leak if safe to do so. Do NOT let product contaminate
drains or waterways. If product does enter a waterway, advise the
Environmental Protection Authority or your local Waste Management. Use
clean, non-sparking tools and equipment.
Clean up methods
Absorb using absorbent non-combustible material such as vermiculite, sand or
soil. Avoid using sawdust or cellulose. Collect material into suitably labelled dry
chemical-waste containers and dispose of promptly as hazardous waste.
Section 7: HANDLING AND STORAGE
Precautions for safe handling
Wear appropriate protective equipment and ensure an eye bath and
safety shower is available for use. Observe good personal hygiene
practices. Take precautionary measures against static discharges by
bonding and grounding equipment. Avoid contact with eyes, skin and
clothing. Do not inhale product vapours.
Conditions of safe storage
Store in a cool, dry, well-ventilated, fire-proof area. Keep containers
tightly sealed when not in use and out of direct sunlight. Inspect regularly
for deficiencies such as damage or leaks. Protect against physical damage.
Ground and bond storage containers. Store away from incompatible
materials and ignition sources. Protect from static charges.
Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
National exposure standards
Biological Limit Values
Engineering Controls
Date of issue: August 2011
3
Acetone: TWA – 500ppm (1185mg/m )
3
STEL - 1000ppm (2375mg/m )
3
2,4,6-Trinitrophenol (Picric Acid): TWA – 0.1mg/m
Not available.
A system of local and/or general exhaust is recommended to keep
employee exposures as low as possible. Local exhaust ventilation is
generally preferred because it can control the emissions of the
contaminant at its source, preventing dispersion of it into the general
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Material Safety Data Sheet
Picric Acid – Acetone
work area. Use a flame proof exhaust ventilation system.
Personal Protective Equipment
Chemical goggles or glasses, gloves, protective clothing and use in wellventilated area.
Section 9: PHYSICAL AND CHEMICAL PROPERTIES
Appearance
Odour
pH
Vapour pressure
Vapour density
Boiling point
Melting point
Solubility
Specific gravity
Information for flammable materials
Upper and lower flammable limits in air
Decomposition temperature
Yellow liquid
Not available
Not available
175mmHg @ 20⁰C
Not available
56⁰C
-95⁰C
Water soluble
0.79
Flash point: -20⁰C (closed cup) (Acetone)
2.6-12.8% (Acetone)
Not applicable
Section 10: STABILITY AND REACTIVITY
Chemical stability
Conditions to avoid
Incompatible materials
Hazardous decomposition products
Hazardous reactions
Stable under recommended conditions for use and storage.
Direct sunlight, heat, ignition sources and incompatibles.
Incompatible with oxidizing agents, acids, reducing agents, bases,
chlorates, perchlorates, chromates and dichromates and Nitrates.
Toxic gases may evolve.
Polymerisation will not occur.
Section 11: TOXICOLOGICAL INFORMATION
HEALTH EFFECTS: As for Acetone
Acute:
Eye contact
Skin contact
Inhalation
Ingestion
Irritating, risk of corneal clouding.
May cause irritation. Will have a degreasing action on the skin.
Prolonged/repeated skin contact may cause skin dryness, cracking and chronic
dermatitis.
Moderately toxic by inhalation. May cause headaches, drowsiness, dizziness,
salivation, nausea, vomiting and coma. Irritating to mucous membranes and
respiratory tract. Narcotic in high concentration.
Moderately toxic. May cause gastric irritation, gastro-intestinal complaints,
headache, salivation, nausea, vomiting, dizziness, narcosis and coma.
TOXICITY DATA: For Acetone
Oral LD50 Rat: 5800mg/Kg Inhale LC50 Rat: > 20mg/L (4hr) Skin LD50 Rabbit: 20000mg/Kg
Skin Irritation: Moderately irritating to rabbit skin.
Eye Irritation: Irritating to rabbit eyes.
Section 12: ECOLOGICAL INFORMATION
Ecotoxicity
Persistence and degradability
Mobility
Environmental fate (exposure)
Bioaccumulative potential
May cause long term adverse effects in the environment.
Not available for this product.
Not available for this product.
Do not contaminate drains and waterways.
Not available for this product.
Section 13: DISPOSAL CONSIDERATIONS
Disposal methods and containers
Date of issue: August 2011
Dispose of in accordance with local authority guidelines.
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Material Safety Data Sheet
Special precautions
Picric Acid – Acetone
Contact a specialist disposal company or the local waste regulator for
advice. This should be done in accordance with 'The Hazardous Waste
Act'.
Section 14: TRANSPORT INFORMATION
Classified as dangerous goods by the criteria of the Australian Dangerous Goods Code.
UN Number
UN Proper shipping name
Class and subsidiary risk
Packing group
Special precautions
Hazchem code
1090
Acetone
3
II
Flammable irritant
2[Y]E
Section 15: REGULATORY INFORMATION
• Dangerous goods of Class 3 (Flammable Liquid) are incompatible in a placard load with any of the
following: Class 1, Class 2.1, if both the Class 3 and Class 2.1 dangerous goods are in bulk, Class 2.3, Class 4.2,
Class 5, Class 6, if the Class 3 dangerous goods are nitro-methane and Class 7.
 Poison Schedule: S6
 TWA (Time Weighted Average): The average airborne concentration of a particular substance when
calculated over a normal eight-hour working day, for a five-day week.
 STEL (Short Term Exposure Limit): The average airborne concentration over a 15 minute period which
should not be exceeded at any time during a normal eight-hour workday.
Section 16: OTHER INFORMATION
Release Information
Date of preparation
Issue Number
31 August 2011
1
References
1.
2.
3.
4.
National Occupational Health and Safety Commission, Approved Criteria for Classifying Hazardous
rd
Substances (NOHSC:1008); Australian Government Publication Service: Canberra (2004), 3 Edition.
National Occupational Health and Safety Commission, List of Designated Hazardous
nd
Substances (NOHSC:10005); Australian Government Publication Service: Canberra (1999), 2 Edition.
National Transport Commission Australian Code for the Transport of Dangerous Goods by Road and
th
Rail (ADG Code); Canprint: Canberra (2007), Volume 1, 7 Edition.
Standards Australia, Dangerous Goods Initial Emergency Response Guide: Australian
Handbook (SAA/SNZ HB76); Homebush (2004).
Copyright © 2011 Point of Care Diagnostics Australia Pty Ltd
Date of issue: August 2011
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