I. II. Regulating the Cell Cycle Section 10-3 Controls On Cell Division i. When cells come into contact with………. Cell Cycle Regulators i. ______________ and ____________discovered that cells in mitosis contained a ______________ that when injected into a nondividing cell would cause a mitotic spindle to form. ii. ___________ is a protein that regulates the timing of the cell cycle in eukaryotes. A. Internal Regulators: Example: B. External Regulators: Example: III. Uncontrolled Cell Growth i. ________________ cells do not respond to the signals that regulate the growth of most cells. As a result, they form masses of cells called tumors that can damage the surrounding tissues. iii. Loss of growth can be caused by iv. All cancer cells have a defect in a gene called ___________, which normally halts the cell cycle until all chromosomes have been properly replicated.
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