Course Name: Microbial Chemistry
Course Code: MCB102, Credits: 3
Class Day/Time: ST, 113.20 – 12.20 AM
Room No.: 10017
Course Instructor: Ashrafus Safa, Ph.D.
Assistant Professor, School of Life Sciences, IUB
Email: [email protected]; [email protected]
Phone: 0171-3433-198 (Cell)
Course Outline:
This course is designed to provide students with basic knowledge on morphology and biochemistry
of various micro and macro life forms — bacteria, viruses, fungi, protozoa, prions, animals and plants.
Molecular structure and function of different biomolecules, for example, proteins, carbohydrates, lipids,
fatty acids will be taught in sufficient details. Various cellular and sub-cellular organelles of prokaryotic and
eukaryotic cells will be discussed. Control of pathogenic microbes using various physical methods, chemical
agents and antibiotics will also be taught. This course will also include a brief discussion on antimicrobial
resistance mechanisms and future therapeutics. After completing this course, students are expected to gain
more knowledge on the structure and function of different cellular constituents of micro and macro
organisms as well as their differences.
Recommended Books:
1. Microbiology: Concepts and Application, International Edition, 1993 – Pelczar MJ Jr, Chan
ECS & Krieg NR. McGraw-Hill, Inc., New York.
2. Prescott, Harley, and Klein’s. Microbiology, 7th Edition, 2008 – Willey J, Sherwood LM &
Woolverton CJ. McGraw-Hill Higher Education, Boston.
3. Microbiology. An Introduction. Gerard J. Tortora, Berdell R. Funke, Christine L. Case. 10th
edition.
1
Lecture Schedule (Summer 2013):
Week(s)
Date
Microbial Chemistry (MCB 102)
Topic(s)
01
08/09/2013 Introduction to major
domains of life
02
03
04
10/09/2013 Do
15/09/2013 Do
17/09/2013 Class Test I
Introduction to
biomolecules
22/09/2013 Do
24/09/2013 Do
29/09/2013 Class Test II
Bacteria: Gram-positive,
Gram-negative,
Cyanobacteria
01/10/2013 Do
06/10/2013 Do
08/10/2013 Archaea: Extreme
halophiles,
Methanogens,
Hyperthermophiles
13/10/2013 Do
15/10/2013 Midterm
20/10/2013 Unicellular Eukarya
05
06
07
08
09
10
11
12
13
14
15
16
17
18
19
20
22/10/2013 Do
27/10/2013 Multicellular Eukarya
29/10/2013 Do
03/11/2013 Introduction to control
of microorganisms
05/11/2013 Do
10/11/2013 Antimicrobial agents
and mode of action
12/11/2013 Do
Details
™ Brief introduction to Microbes and their chemistry
™ The three domain-system — Bacteria, Archaea and
Eukarya
™ Basic features of representatives from different superkingdoms:
ƒ Bacteria: Gram-positive, Gram-negative, Cyanobacteria
ƒ Archaea: Extreme halophiles, Methanogens,
Hyperthermophiles
ƒ Eukarya:
• Unicellular: Fungi (Yeast); Protozoans (Trypanosoma,
Amoeba, Giardia, Paramecium); Slime
molds (Cellular and Plasmoidial)
• Multicellular: Animals, Plants, Fungi (Molds),
Chromista (Algae)
Cont.
Cont.
Carbohydrates, Lipids, Proteins and Nucleic acids
Cont.
Cont.
Molecular structure and function of cellular and sub-cellular
organelles
Cont.
Cont.
Molecular structure and Function of Cellular and Sub-cellular
organelles
Cont.
Molecular structure and Function of Cellular and Sub-cellular
organelles
Cont.
Molecular structure and Function of Cellular and Sub-cellular
organelles
Cont.
Control of microorganisms by physical, chemical and
antimicrobial agents
Cont.
Classification of antibiotics; Cell-wall synthesis inhibition;
Protein synthesis inhibition
Cont.
2
21
17/11/2013 Do
22
19/11/2013 Resistance mechanism
23
24/11/2013 Do
24
26/11/2013 Introduction to biomedical
journals
Nucleic acid synthesis inhibition; Metabolic pathway
inhibition
Drug resistance mechanism and prevention, Alternative
chemotherapeutic agents
Drug resistance mechanism and prevention, Alternative
chemotherapeutic agents
Scope and types of research articles; Reading and analyzing research
articles
08/12/2013
Final Exam
3
Marks Distribution:
Events
Duration
Breakdown
Class Test I
25 mins.
10%
Class Test II
25 mins.
10%
Midterm
70 mins.
30%
Final
90 mns.
40%
Assignment/Presentation
—
5%
Attendance
—
5%
Total
—
100%
Grading Policy:
Grade
Explanation
Quality Points
A
Excellent
4.0
A-
Excellent
3.7
B+
Good
3.3
B
Good
3.0
B-
Good
2.7
C+
Passing
2.3
C
Passing
2.0
C-
Passing
1.7
D+
Deficient Passing
1.3
D
Deficient Passing
1.0
P
Pass
0.0
R
Referred
0.0
F
Failing
0.0
I
Incomplete
0.0
W
Withdrawal
0.0
S
Satisfactory
0.0
U
Unsatisfactory
0.0
O
Administrative Withdrawal
0.0
Y
Audit
0.0
Z
No Grades Received
0.0
4