List of Abbreviations
List of Abbreviations
OVI
Organic volatile impurity
ICH
International Conference on Harmonization
BPCs
Bulk pharmaceutical chemicals
PDE
Permitted daily exposure
TTC
Threshold of toxicological concern
SPE
Solid-phase extraction
SAX
Strong anion exchanger
WAX
Weak anion exchanger
SCX
Strong cation exchanger
WCX
Weak cation exchanger
SFE
Supercritical fluid extraction
API
Active pharmaceutical ingredients
INH
Isonaizid
PYZ
Pyrazinamide
FDC
Fix dosage combination
SC-CO2
Supercritical carbon dioxide
ODS
Octadecyl silane
EMB
Ethambutol
MRM
Multiple reaction monitoring
RRT
Relative retention times
ESI
Electron spray ionization
m/z
Mass to Charge ratio
LOD
Limit of detection
LOQ
Limit of quantitation
xv