UNT Lesson Plan Teacher: Subject area: Megan Fokken Date: Biology Grade Level: Dec 5/6 9 District: Unit Title DISD Gene Expression School: Lesson Title: Guyer Transcription, Translation and Mutation Purpose and Lesson Standard(s): Understanding goals(s): Essential Question(s): TEKS Biology 6: The student knows the mechanisms of genetics, including the role of nucleic acids and the principles of Mendelian Genetics. The student is expected to:(A) identify components of DNA, and describe how information for specifying the traits of an organism is carried in the DNA;(B) recognize that components that make up the genetic code are common to all organisms;(C) explain the purpose and process of transcription and translation using models of DNA and RNA;(D) recognize that gene expression is a regulated process;(E) identify and illustrate changes in DNA and evaluate the significance of these changes. Students will understand the two process of protein synthesis: transcription and translation. They will understand that transcription occurs in the nucleus, and translation occurs in the cytoplasm/ribosomes. Students will know the flow of information in transcription and translation. Students will also know how to code for proteins using the codon chart. Finally, the will understand how point and frameshift mutations effect protein synthesis. Where does transcription take place? Where does translation take place? How many nucleotides are in a codon? What is the start codon for translation to begin? What is the role of mRNA? What is the role of tRNA? What is a gene? Student Objectives: Assessment of Objectives: Lesson Steps/Activities including Timeline & Grouping -Students will be able to list the sugars, bases, number of strands, and locations of RNA and DNA with 90% accuracy. -Students will be able to identify the location within the cell that transcription and translation occurs. -Students will identify the roles of DNA, mRNA, tRNA and the ribosomes in transcription and translation with 80% accuracy. -Students will be able to code for proteins using a codon chart with 100% accuracy. -Students will know the definition of mutation, frameshift, and point mutations with 80% accuracy. Students will be asked questions through ppt, and they will answer on whiteboards. They will also be using the whiteboards to decode. The whiteboards will allow the teacher to make informal assessments of student understanding. Formal assessment will include a quiz and questions will be on the semester test. Anticipatory Set: Review over transcription and translation, and why cells and organisms need proteins. Teaching: Input: A PowerPoint over gene expression was to be given prior to this lesson. Teaching will be not an introduction, but a reiteration of the material. The teacher will draw the transcription and translation processes on the board. The PowerPoint shows mutations, and will explain frameshift and point mutations and possible effects of mutations. Teaching: Modeling: The teacher will model the transcription and translation processes throughout the PowerPoint. The teacher will demonstrate what is steps are needed to take to transcribe DNA to mRNA, find the codons, and then translate mRNA to amino acids. Teaching: Checking for Understanding: The PowerPoint will include essential questions, and students will use the whiteboards to answer the questions. Also, the students will use to boards to code for proteins, which will allow the teacher to assess their understandings of how to use the codon charts. Guided Practice: Throughout the PowerPoint, the teacher will ask for help to transcribe DNA to mRNA, find the codons, and translate mRNA to proteins using the codon chart. Answers will be shown on the PowerPoint so students can check the right answers. Closure: The teacher will review point and frameshift mutations, and what possible effects they can have on building a protein. Independent Practice: Students will be given a worksheet to practice transcribing and translating DNA. They will also be given a worksheet that asks questions about mutations. 1 UNT Lesson Plan Language Modifications Special Needs Modifications Pictures are included in the power points to provide visuals to the concepts. Students will have the opportunity to work with a classmate to answer class questions. Students with special needs will be assisted by the teacher to check for understanding. Students with language modifications are allowed to work with a bilingual student. Materials & Resources: Technology: Coding and Mutation ppt Whiteboards and pens Laminated Coding Charts Mutation worksheet Power point and overhead projector Reflection What worked: What parts of the lesson led to engagement and student learning? Improvements: How can you increase student learning, engagement, etc, next time you teach this lesson? Students enjoyed using the whiteboards to answer questions. Most students were actively involved in answering the questions during the check for understanding portion of the lesson. Next time, I would like to pull in more real-life stories, or analogies, or something that they can relate to a little more…especially when talking about mutations. I had to monitor the students to make sure they were using the decoding sheet correctly. I think it would be fun to break the students into teams, or have some sort of game, that they kind of teach each other on how to use the charts. The Codon Bingo was effective in getting students to use the charts, but I would like to have some sort of puzzle for the students. I will have to think about that…. Again, I would like to have more point mutation examples. Or have a better worksheet that that has puzzles that students can work on together…a more exploratory lab that they can work in groups with. Overall Implications for your teaching: What did you learn from teaching this lesson that can apply to other lessons? Content that is very theoretical and hard to see happening in real life is hard to teach students. Visuals and even videos are a must. Checking for understanding is a must. I like using the whiteboards, and so do the students. I wish I had clickers…that would be a good tool for assessment during complicated lessons. But I think in lessons like that, the more they draw and practice, they better they’ll be in understanding certain mechanisms. 2
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