Intra-mammary antibiotic options
for the treatment of mastitis during lactation
Intra-mammary antibiotics are usually the first option in the treatment of mastitis during lactation.
The type of antibiotic that will be effective in treating the mastitis should ideally be based on culture
results (see articles on page 1 and 2). If you want to treat with antibiotics immediately rather than
waiting for culture results it is recommended that you collect a milk sample before treating the
affected quarter and place the sample in the freezer. If the mastitis does not respond to treatment
the untreated sample can be cultured to find out if there is a more suitable treatment option.
Product
Active ingredient
Antibiotic class
Treatment
period
Milk withhold period
(after last treatment)
Meat withhold period
(after last treatment)
Total time out
of the vat
Clavulox LC
Amoxycillin 200mg
Clavulanic acid 50mg
B-lactam
B-lactam
1 tube every
12 hours for 3
treatments
48 hours
(4 milkings)
7 days
3.5 days
(7 milkings)
Cerfuroxime 250mg
Cephalosporin
1 tube every
12 hours for 3
treatments
72 hours
(6 milkings)
7 days
4.5 days
(9 milkings)
Cefuroxime 250mg
Cephalosporin
1 tube every
12 hours for 3
treatments
72 hours
(6 milkings)
7 days
4.5 days
(9 milkings)
Novobiocin 100mg
Neomycin 105mg
Dhydrostreptomycin 100mg
Aminocoumarin
Aminoglycoside
Aminoglycoside
1 tube every
24 hours for 3
treatments
72 hours
(6 milkings)
30 days
6 days
(12 milkings)
Amoxycillin 200mg
Clavulanic acid 50mg
B-lactam
B-lactam
1 tube every
12 hours for 3
treatments
84 hours
(7 milkings)
7 days
5 day
(10 milkings)
Cloxacillin 200mg
B-lactam
1 tube every
48 hours for 3
treatments
96 hours
(8 milkings)
30 days
10 days
(20 milkings)
Cloxacillin 200mg
B-lactam
1 tube every
48 hours for 3
treatments
96 hours
(8 milkings)
30 days
10 days
(20 milkings)
Oxytetracycline 185mg
Oleandomycin 100mg
Neomycin 100mg
Tetracycline
Macrolide
Aminoglycoside
1 tube every
24 hours for 3
treatments
168 hours
(14 milkings)
30 days
10 days
(20 milkings)
Maxalac LC
Cepravin LC
Special Formula 17900 Forte V
Clavet LC
Orbenin LC
Noroclox LC
Mastalone
The Vet Group has endeavoured to ensure that all information in this document is correct. However, we make no warranty with regard to the accuracy
of the information and will not be liable if the information is inaccurate, incomplete or out of date. Its contents should not be used as a substitute for
seeking personalised professional advice.
The Vet Group Farm Services
Phone: 1300 838 700 or 1300 VETS 00