FACT vs. HYPE:
You make the call
lves”
ted Mitroflow Va
ilure in Explan
ough
Fa
th
of
en
es
ev
od
,
“M
ay
negative w
a
d colleagues,
in
an
u
ny
yo
tany
ta
to
Bu
Bu
d
r.
h
r. Jagdis
valves” D
or presente
ical study by D
n of “over 600
be interpreted
og
em
io
ol
ay
th
at
m
ph
of
rv
y
or
se
ve
er
m
ob
Fi
rg
nt
r
D.
A rece
oracic Su
g a 10 -yea
fied as SV
e Annals of Th
positive. Durin
nnot be classi
itis, and
rd
ca
ry
ca
ts
ve
do
e
an
pl
ar
en
e
ex
published in th
ith
lv
va
infected w
ever, all 12
the Mitroflow
p.1623) were
explants. How
rditis cases is
the results for
oflow Valves,”
e five endoca
ors studied 12
itr
th
at
M
ig
of
d
st
se
on
ve
ci
iti
in
os
Ex
w
sp
and his fello
gic Findings of
to SVD, the di
mar y of Histolo wn.” (p.1621)1 With respect
(Table 2: “Sum
no
nk
“u
n
ere listed as
sive of infectio
follows:
two of them w
ed valve (exclu
at
Guidelines as
er
S
op
ST
e
e
th
th
g
in
in
2
defined
tion involv
(p.1490)
ion or deteriora
udes dysfunct
investigation.”
cl
al
in
ic
n
in
tio
cl
ra
or
rio
y,
autops
dings.
lve dete
“Structural va
D histologic fin
by reoperation,
seven non- SV
SVD
of
, as determined
l
s)
er
ta
si
nt
to
bo
ce
a
m
r
tifo
ro
ul
th
m
or
enomenal
two unknowns
ph
e
a
th
ts
ith
en
w
es
g
pr
on
The data re
excluded al
600 patients.
e must also be
explants out of
d
Thus, these fiv
te
la
re
elv
ly five va
Indeed,
This leaves on
ear period.
oflow valves.
explanted Mitr
8% over a 10 -y
e
0.
th
es was
of
lv
of
e
va
e
nc
fiv
rn
r
rre
occu
the to
res evident fo
3,4 All but one of
ilu
fa
e
e of
lv
.
va
te
es
al
t the exis nc
hetic valv
e structur
that there wer
ardial bioprost
uncertain abou
e
s
ric
ut
hich
pe
w
em
sp
di
in
of
se
l
lf
s,
no
ca
ar
se
is
pi
te
m
There
ed are ty
Butany hi
had cusp
ilures describ
of our valves
cation
docarditis. Dr.
ifi
5)
lc
en
=
ca
ith
(n
if
w
e
%
is
ed
42
ct
the types of fa
rm
infe
is series,
cult to su
one was also
ification): “In th
tation, it is diffi
calcified, and
related to calc
ges. At explan
un
ed
s
ar
ar
te
te
e
e.
th
(i.
at
n
primar y tears
with calcificatio
Heart
as associated
5)
62
®
.1
(p
all except 1 w
”
rtic Pericardial
s.
ar
Mitroflow Ao
llowed the te
ented
rin
fo
es
So
or
pr
e
ed
ce
th
ed
en
of
ec
id
pr
performance
thors, the ev
ic
au
e
am
th
yn
by
od
m
provided
ural and he
e conclusion
rostheses.
ng-term struct
5,6 Contrary to th
Mitroflow biop
d.
The proven lo
e
th
he
lis
of
y
ab
lit
st
bi
l-e
ra
el
du
w
l
na
en
io
be
pt
s
Valve ha
f of the exce
. is further proo
by Butany et al
ay Con
To Whom It M
cern:
Sincerely,
Sorin Group
–1628.
2011;92:1621
Mayer J, Ly tle
n Thorac Surg.
ial Valves. An
ian D, Hagl S,
ah
ard
Sh
ric
D,
Pe
s
w
am
flo
Ad
tro
Mi
E,
d
art
nte
tch
pla
Bu
Ex
T,
of Failure in
90 -1495.
07;22:7-12.
enberg J, David
Nair V. Modes
rg. 20 08;85:14
J Card Surg. 20
meier G, Takk
References
Law K, Suri R,
cal Explants.
Ann Thorac Su
ne E, Gr unke
Feng T, Luk A,
dings in Surgi
Interventions.
os N, Blacksto
Valve Dis.
Fin
uk
lve
art
al
ho
Va
He
gic
uc
J
ac
.
Ko
olo
rdi
1. Butany J,
ion
M,
rph
Ca
the Aortic Posit
nt Valves – Mo
ller DC, Turina
Morbidit y Af ter
prosthesis in
y
wards Perimou
Mortality and
2. Akins C, Mi
Peric ardial Bio
esis: Durabilit
for Reporting
Carpentier- Ed
ntier- Edwards
G, Feindel C.
B. Guidelines
ardial bioprosth
or
rpe
So
Ca
S,
the
g
of
on
Mitroflow peric
des
V, Le
ir
Mo
the
h
Na
re
J,
ilu
wit
t
y
Fa
en
tan
E.
3. Bu
ckstone
valve replac em
ric ardial
Smedira N, Bla
tzer R. Aortic
of Mitroflow pe
4. Roselli E,
tre evaluation
Siniawski H, He
28.
-year, multic en
Detschades C,
20
6.
J,
a
in
-69
20 06;15:421-4
S):
88
Ste
MU
6:6
M,
i
TH
Surg. 20 08;13
ive results (IS
Pasic M, Musc
c Cardiovasc
5. Yankah C,
flow postoperat
years. J Thora
dy on the Mitro
results up to 21
The Italian stu
rs.
ato
.
tig
-26
es
US Inv
11;39:18
6. The ISTHM Eur J Cardiothorac Surg. 20
bioprosthesis.
Heart Valves
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