Usefulness of the Editor Note Field
(/ENTE) in CAS REGISTRYSM
Database
Science IP®, The CAS Search Service.
CAS REGISTRY database, the gold standard for chemical information, contains more than 68
million unique organic and inorganic chemical substances, such as alloys, coordination
compounds, minerals, mixtures, polymers and salts, and more than 63 million sequences.
In REGISTRY, many substance records with incompletely known structures or complex
mixtures contain the Editor Note field (/ENTE). The /ENTE field provides more information on
unfamiliar product designations, names (synonyms), or lab codes, and gives a description to
better understand the structure and its use. Substances with /ENTE fields commonly include:
 Commercially available product names
 Products made from mixtures of natural products
 Biologics
You can find /ENTE information for specific substance records using the standard default display
IDE (substance IDEntification) format in REGISTRY. For example, you can EXPAND and SEARCH
on a product designation using the Chemical Name (/CN) field to locate the REGISTRY record.
DISPLAY will show the default format IDE including various information such as the /ENTE field
for substances lacking structures. Also, you can search by CAS Registry Number® (CAS RN) or
the name(s) of the substance in databases with and without CAS RN indexing.
Example 1: IDE display format for Tridemorph, a complex mixture.
=> FILE REGISTRY
=> SEARCH
BAS 2203f/CN
=> DISPLAY
L1
ANSWER 1 OF 1 REGISTRY COPYRIGHT 2012 ACS on STN
RN
81412-43-3 REGISTRY
The /ENTE field indicates this substance
ED
Entered STN: 16 Nov 1984
CN
Tridemorph (CA INDEX NAME) is a fungicide with a structure
OTHER NAMES:
consisting of a complex mixture of
CN
BAS 2203F
alkyl groups with likely variable
CN
Calixin
CN
Calixin 86 OL
percentages of each alkyl chain length.
CN
Elbamorph
ENTE Mixed C11-14-alkyl-2,6-dimethylmorpholines; fungicide
MF
Unspecified
CI
COM, MAN
LC
STN Files: AGRICOLA, BIOSIS, BIOTECHNO, CA, CABA, CAPLUS,
CHEMCATS, CHEMLIST, CIN, DDFU, DRUGU, EMBASE, IFICDB, IFIPAT,
IFIUDB, RTECS*, TOXCENTER, ULIDAT, USPAT2, USPATFULL
(*File contains numerically searchable property data)
*** STRUCTURE DIAGRAM IS NOT AVAILABLE ***
**PROPERTY DATA AVAILABLE IN THE 'PROP' FORMAT**
773 REFERENCES IN FILE CA (1907 TO DATE)
168 REFERENCES TO NON-SPECIFIC DERIVATIVES IN FILE CA
779 REFERENCES IN FILE CAPLUS (1907 TO DATE)
In Example 1, we located the REGISTRY record using the lab code of interest. You can
retrieve 779 references containing Tridemorph using the CAS RN to search in CAplus SM
database.
Example 2: IDE display format of Apelin, a biologic.
=> FILE REGISTRY
=> S APELIN/CN
=> DISPLAY
L1
ANSWER 1 OF 1 REGISTRY COPYRIGHT 2012 ACS on STN
RN
372170-33-7 REGISTRY
ED
Entered STN: 29 Nov 2001
The /ENTE field provides a broad
CN
Apelin (CA INDEX NAME)
OTHER NAMES:
informative description for this
CN
Apelin, preprobiologic.
CN
Preproapelin
DR
556104-78-0
ENTE An orphan receptor ligand peptide
MF
Unspecified
CI
MAN
SR
CA
LC
STN Files: BIOSIS, CA, CAPLUS, IPA, TOXCENTER, USPAT2, USPATFULL
*** STRUCTURE DIAGRAM IS NOT AVAILABLE ***
526 REFERENCES IN FILE CA (1907 TO DATE)
5 REFERENCES TO NON-SPECIFIC DERIVATIVES IN FILE CA
554 REFERENCES IN FILE CAPLUS (1907 TO DATE)
Both substance records in the examples contain additional synonyms, although this is not
necessarily true for all compounds with /ENTE entries.
Substances retrieved through structure searching lack the /ENTE field in REGISTRY because a
structure is available to display. Incompletely known structures include those with undisclosed
material compositions, or where exact structures are unknown, such as biologics (Apelin in
Example 2). When structural information becomes available, CAS updates the record and the
substance becomes structure or sequence searchable.
In REGISTRY, compounds can be indexed by structure as “Incompletely described substances”
(IDS) in the Class Identifier (/CI) field. This is done for compounds whose molecular formula is
known, but for which the exact structure is not known (e.g., the location of specific
substituents). IDS compounds are indexed by structure and can be retrieved in a structure
search.
In summary, the Editor Note field can be used to describe substances lacking an exact
composition or for complex mixtures. This information provides a better understanding of the
product since no structure is available. You can retrieve references to substances with /ENTE
field information by searching their CAS Registry Number in CAplus and other databases on
STN.
STN provides access to key science, technology and patent databases, and is the premier single
source for the world’s disclosed scientific and technical research. STN databases such as CAS
REGISTRY can be accessed through STN Express®, STN® on the WebSM and STN Easy®. To find
more information about the REGISTRY database or other display fields, please contact CAS
Customer Center or refer to the CAS REGISTRY Database Summary Sheet at:
http://www.cas.org/File%20Library/Training/STN/DBSS/registry.pdf.
Note: This search example was provided by Science IP®, the CAS Search Service.