Kidneys 2017 adrenal gland Label & color prostate Label & color Glomerulus (singular) Glomeruli (plural) adrenal gland Label & color prostate -20 WE pts if I see a phone The Urinary System •2 kidneys •2 ureters •1 bladder •1 urethra Have 2 Can live c only 1 Vital!!! Very vascular In postero of laparo postero hepato & gastro The urinary tract is supposed to be a STERILE PLACE!!! Nephrology • A&P of kidneys • Kidney disorders • Ex. Kidney failure • NO surgery Urology • Deals with ‘plumbing’ • Males, females, all ages • Ex. UTI’s, kidney stones • Also, male reproduction (ex. ED, prostate) • Also a surgeon Basic Steps • Fresh O2 blood, lungs > heart • Heart beats, blood to aorta > arteries > organs • Aorta > renal arteries > kidneys • Nephrons in kidneys filter blood, removing ‘junk’ • Clean blood > renal veins > heart & lungs, repeat • Junk + H2O + pigment (UROCHROME) = urine • Urine drips down kidney pelvis > ureter > bladder > urethra > out So the kidneys clean our blood & make urine…is that all they do? Water Balance • K’s maintain basic water balance by urinating & recycling • Too much H2O in blood = more pee • Too little H2O in blood = less pee • Gauge by the color of urine • Homeostasis Electrolyte Balance • K’s constantly monitor/regulate blood’s levels of electrolytes • Na, Cl, Ca, K • Needed for muscles / nerves • oligo electrolytes = death • Homeostasis Rid wastes from blood • Urea (proteins) • Nephrons clean blood & eliminates wastes • BUN = Blood Urea Nitrogen Regulate BP • K’s make hormone RENIN • Renin regulates Na in blood • Too much Na in blood = BP • Ever heard of pt c HBP to cut down on Na foods? • Na > edema > excess blood volume > HBP Build RBC’s • K’s make hormone ERYTHROPOIETIN • Which stimulates bone marrow to make RBC’s Blood’s pH • Blood pH = 7.35 – 7.45 • VERY narrow window of ‘normal’ • Ex: Uncontrolled diabetes > acidic blood • > multiple organ death Look closely at kidneys Look closely at kidneys • Basic cells of K’s • ≈ 1 million/kidney • Fragile, delicate, tiny but mighty • Glomeruli + tubules do all the kidney’s work Look closely at kidneys When nephrons make urine, it … • Constantly drips from kidney pelvis into ureter • Collects in bladder • Exits thru urethra What is a urinalysis? U/A • Mash-up of 2 words: urine + analysis • “pee in a cup” • Indicates general health, not only of K’s What is a urinalysis? • Albumin = protein • Healthy kidneys do not ‘spill’ protein into urine • So, PRO in urine is serious! What is a urinalysis? • Glucose = Blood Sugar • Glucose in urine = diabetes What is a urinalysis? • WBC’s in urine = infection • WBC’s indicate urine no longer sterile • UTI = urinary tract infection What is a urinalysis? • RBC’s = bleeding • Could be stones, UTI, tumors, trauma, etc. • HEMATURIA What is a urinalysis? • pH of urine • Slightly acidic in AM (6.5 – 7.0) • More alkaline as we eat/drink (7.5 – 8.0) Ureters • Pair of tubes • Kidney pelvis to bladder • Peristalsis Bladder • “Balloon” that expands • Hollow & muscular • Lined with mucous membrane Bladder • Voluntary ; Sphincter • M&F: In front of rectum • F: In front of vagina & below uterus • M = larger. Why??? Urethra • Narrow tube • Drains urine from bladder • MUCH shorter in F • MUCH longer in M Prostate • Male repro structure • At base of bladder • Surrounds urethra • In older men, hypertrophies • CA vs. Benign What is urinary incontinence? • Lack of voluntary bladder control • Babies: sphincters immature so bladder empties when it’s full • As we grow, our urinary sphincters mature so we can control when we pee • Older adults may lose this control • Smokers have this x2 Aging urinary system • Kidneys – shrink, decreased blood flow, filter less • Kidney diseases more common • Sensation of thirst decreases > dehydration • UTI’s more common • Incontinence more common Do you recall these items of medical equipment? • Catheter & Foley bag? • Specimen cup? • Bedside commode? • Endoscope? Esp. cystoscope? • Urine strainer? • Briefs? (NOT diapers) • Urine dipstick One type of ________ CYSTOSCOPY CYSTOSCOPY CYSTOSCOPY • https://www.youtube.com/watch?v=d9Vx3Lgz4sw Kidney Stones aka NEPHROLITHIASIS • https://www.youtube.com/watch?v=LngbrHJkXoE Kidney Stones aka NEPHROLITHIASIS 1. Common or rare? Circle one 2. More common in this sex: _____________________________ 3. The K’s are 2 B____-shaped organs located near the M______ of the back. 4. They work as F________ removing W_______ P__________ & E___________ F__________ from the blood & return C______________ B___________ to the body. The waste products & excess fluid become U___________. 5. Urine travels from the kidneys thru 2 narrow tubes called U____________, to the B___________ and leaves the body thru the U_________________. 6. If there is a chemical imbalance in the composition of the urine, C____________ can form which can build up into stone-like lumps 7. ID 3 causes of kidney stones: 1.D__________________________ 2. A diet high in P__________________ and 3 Other medical conditions such as 8.____________ _____________ ____________. Kidney Stones aka NEPHROLITHIASIS 9. If stones are small, how do they usually leave the body? __________________________ 10. Larger stones can get ‘stuck’ in the kidneys. 11. Kidney stones are often tx’d with IV F______________ and P_________ K____________. However, in the case of infection or obstruction, other interventions can become necessary. 12. Describe shock way therapy (AKA ESWL, or extra-corporeal shock wave lithotripsy) 13. Describe percutaneous nephrolithotomy. 14. Describe ureteroscopy. Kidneys & NSAID’s • Recall: Non-Steroidal Anti-Inflammatory Drugs • Ex: ASA, Motrin (Ibuprofen), Aleve (naproxen) -- (NOT Tylenol!) • NSAID’s reduce blood flow thru kidneys • Thus, NSAID’s can damage the kidneys • Pts w/ impaired renal fxn should avoid NSAID’s • NSAID overdose can lead to acute renal failure UTI, or Urinary Tract Infections, or bladder infections, or cystitis • If you unable to ID the 4 parts of the urinary tract, list them here • Most common: bladder & urethra • F>M why? • Antibiotics to kill E.Coli • Cranberry juice https://www.youtube.com/watch?v=u11DfF6fuCM UTI Cause(s) • Bacteria climb up urethra (E.Coli) • STI • Prostate issues • Incontinence • Catheter use UTI S/S • Urgency • Frequency • Dysuria • Smelly pee • Cloudy or pink urine BPH & Prostate CA • Men >50 • Hypertrophied prostate • Benign vs. malignant • PSA • Digital rectal exam https://www.youtube.com/watch?v=aLPqzYMg42Y https://www.baptistjax.com/health-library/symptoms/urinary-incontinence BPH & Prostate CA • https://www.youtube.com/watch?v=flHXrnSWxCU • Robotic prostatectomy • https://www.youtube.com/watch?v=2XKnkB7p_l8
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