Mitosis and cytokinesis
chromosomes (each a
pair of sister chromatids
joined together)
mitotic
spindle
pair of
entrosomes
nucleus
replicated,
ncondensed
DNA
metaphase
plate
spindle fibers
(microtubules)
Prophase
mitosis begins
End of interphase
DNA has already
duplicated back in S
phase. Centrosome has
doubled.
Chromosomes take shape;
the two centrosomes begin
to move toward the cellular
poles, sprouting
microtubules as they go.
Metaphase
attachment and alignment
Microtubules attach to sister
chromatids and align them
at the metaphase plate.
Mitosis and cytokinesis (cont.)
separating
chromatids
cleavage
furrow
spindle fibers
shortening
Anaphase
separation
Sister chromatids are moved
to opposite poles in the cell,
each chromatid now
becoming a full-fledged
chromosome.
Telophase and cytokinesis
exit from mitosis
Chromosomes decondense;
nuclear envelopes form around
the two separate complements
of chromosomes. Cleavage
furrow begins to form.
Completion of cytokinesis
one cell becomes two
The cell membrane pinches
together completely;
membranes on either side
fuse together, creating two
cells.
Beginning of
interphase
These two cells now
enter the G1 phase of
interphase.
David Krogh, A BRIEF GUIDE TO BIOLOGY, 1/e © 2007 Pearson Prentice Hall, Inc.
Figure 9.10