BIOH122 Session 5
Capillary Exchange
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Module: Distribution
Title: Capillary Exchange
Introduction
1. Describe the relative movement of oxygen, carbon dioxide, and other wastes,
between capillaries and living cells.
Mechanisms of Capillary Exchange
2. a. Describe the importance of diffusion as a method of capillary exchange.
b. Describe movement of small or lipid soluble molecules across the endothelial cell
membrane.
c. Describe movement of medium-sized, or lipid insoluble soluble substances across the endothelial cell
membranes.
3. Describe transcytosis. Include endocytosis and exocytosis in your explanation.
4. a. What does bulk flow transport?
b. How do pressure gradients affect bulk flow?
c. Describe the function of capillary fenestrations.
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Bulk Flow
5. Describe the correlation between bulk flow and the relative volumes of blood and
interstitial fluids.
6. Explain each of the following factors that determine the net direction of capillary
exchange.
Blood Hydrostatic Pressure (BHP) -
Blood Colloid Osmotic Pressure (BCOP) -
Interstitial Fluid Osmotic Pressure (IFOP) –
Interstitial Fluid Hydrostatic Pressure (IFHP) -
7. Define Net Filtration Pressure (NFP).
8. a. Describe filtration and reabsorption pressures at each of the following capillary locations.
Arterial End Venous End b. How much of the water that is filtered out of the arterial end of the capillary is reabsorbed at the venous
end?
9. What happens to the interstitial fluid not reabsorbed into the venous capillaries?
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10. a. Define oedema.
b. Name four major causes of oedema.
Blood Velocity
11. a. Describe the relationship between blood velocity and blood vessel cross-sectional area.
b. Why is slow blood velocity important in the capillaries?
12. Describe blood velocity patterns as blood moves away from, and then back toward, the heart.
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Last updated on 7-Nov-16
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