UNIT 4 WARM UPS Meiosis and Heredity 10/10 – BIO Warm UPs 1. 2. When are mutations most likely to occur? Are mutations random or planned? 10/10 – BIO Warm UPs When are mutations most likely to occur? 1. 1. Most occur during meiosis or mitosis – whenever the DNA is replicated for cell division Are mutations random or planned? 2. 1. Mutations are random changes in the DNA 10/11 – BIO Warm UPs 1. Explain why some people are lactose tolerant and some people are lactose intolerant. 10/11 – BIO Warm UPs 1. Explain why some people are lactose tolerant and some people are lactose intolerant. 1. Humans normally lose the ability to digest lactose (they stop making the enzyme lactase) as they get older because only babies need to digest milk. In Europe and Africa mutations occurred that allowed some people to continue to make the enzyme lactase as adults. These people became lactose tolerant. People who were lactose tolerant were more likely to survive droughts and other hardships, so this gene became more common in these regions. 10/12 – BIO Warm UPs 1. 2. 3. What is the difference between homologous chromosomes and sister chromatids? In what stage of meiosis do homologous chromosomes separate? In what stage of meiosis do sister chromatids separate? 10/12 – BIO Warm UPs 1. What is the difference between homologous chromosomes and sister chromatids? 1. 2. 3. Homologous chromosomes are similar but not identical. Each carries the same genes in the same order, but the alleles for each trait may not be the same. One chromosome of each homologous pair comes from the mother and one comes from the father. Sister chromatids are identical copies of a chromosome. When chromosomes replicate in S phase, they form sister chromatids. In what stage of meiosis do homologous chromosomes separate? Meiosis I In what stage of meiosis do sister chromatids separate? Meiosis II 10/13 – BIO Warm UPs 1. 2. Explain the difference between diploid and haploid. At what stage in meiosis do the cells become haploid? 10/13 – BIO Warm UPs Explain the difference between diploid and haploid. 1. 1. 2. Diploid cells contain two complete sets of chromosomes, one from each parent. Haploid cells contain one set of chromosomes. Gametes or sex cells (sperm and egg) are all haploid. At what stage in meiosis do the cells become haploid? 2. 1. Cells become haploid after telophase I in meiosis I. Diploid vs Haploid X y y Prophase I y X X y Cytokinesis X y X Metaphase I Anaphase I Telophase I y y y Prophase II Metaphase II y y Telophase II and Anaphase II Cytokinesis y X X X X X X 10/14 – BIO Warm UPs What is crossing over? In what part of meiosis does it occur? 2. What is independent assortment? In what part of meiosis does it occur? 3. If diploid cell with 10 chromosomes undergoes meiosis to form gametes, how many chromosomes will each gamete have? Are the gametes haploid or diploid? * Gametes are sex cells (sperm and egg) 1. 10/14 – BIO Warm UPs What is crossing over? In what part of meiosis does it occur? 1. 1. Homologous chromosomes swap genes. It occurs in prophase 1 of meiosis 1. What is independent assortment? In what part of meiosis does it occur? 2. 1. Homologous chromosomes line up randomly during metaphase 1 of meiosis 1. If diploid cell with 10 chromosomes undergoes meiosis to form gametes (sex cells – sperm and egg), how many chromosomes will each gamete have? Are the gametes haploid or diploid? 3. 1. Each gamete will have 5 chromosomes. They are haploid. 10/17 – BIO Warm UPs 1. 2. What is the difference between phenotype and genotype? What is the difference between homozygous and heterozygous? 10/17 – BIO Warm UPs 1. What is the difference between phenotype and genotype? 1. 2. Genotype is the combination of alleles. Phenotype is the physical trait that is determined by the genotype. What is the difference between homozygous and heterozygous? 1. Homozygous has two of the same alleles (TT or tt). Heterozygous has two different alleles (Tt). 10/18 – BIO Warm UPs 1. Purple flowers (B) are dominant to white flowers (b). Cross two plants that are heterozygous for purple flowers. 1. 2. 3. Draw the Punnett Square What is the genotypic ratio for the offspring? What is the phenotypic ratio of the offspring? 10/18 – BIO Warm UPs 1. Purple flowers (B) are dominant to white flowers (b). Cross two plants that are heterozygous for purple flowers. Draw the Punnett Square 2. What is the genotypic ratio for the offspring? ¼ BB: ½ Bb: ¼ bb 3. What is the phenotypic ratio of the offspring? ¾ Purple flowers: ¼ White flowers 1. 10/19 – BIO Warm UPs 1. 2. A woman with a genotype of IAi has children with a man with a genotype IBi. What are the genotypic and phenotypic ratios for their offspring? Are these examples of codominance or incomplete dominance: 1. A horse can have three possible phenotypes: Black (BB), White (WW) or Gray (BW). 2. A flower can be Yellow (CYCY), White (CW CW) or Yellow and White (CW CY) 10/19 – BIO Warm UPs 1. 2. A woman with a genotype of IAi has children with a man with a genotype IBi. What are the genotypic and phenotypic ratios for their offspring? Genotypic: ¼ IAIB : ¼ IAi : ¼ IBi : ¼ ii Phenotypic: ¼ Type AB: ¼ Type A: ¼ Type B: ¼ Type O Are these examples of codominance or incomplete dominance: 1. A horse can have three possible phenotypes: Black (BB), White (WW) or Gray (BW). Incomplete Dominance 2. A flower can be Yellow (CYCY), White (CW CW) or Yellow and White (CW CY) Codominance 10/20- BIO Warm Up 1. 2. A colorblind man has children with a woman who is a carrier for colorblindness. What are the genotypic and phenotypic ratios of their offspring? If a male inherits a sex-linked trait, like hemophilia, which parent did he inherit it from? How do you know? Explain. 10/20 - BIO Warm Up A colorblind man has children with a woman who is a carrier for colorblindness. What are the genotypic and phenotypic ratios of their offspring? XB=normal, Xb=colorblind 1. 1. 2. ¼ XBXb : ¼ XbXb : ¼ XBY : ¼ XbY ¼ female, carrier : ¼ female colorblind : ¼ male normal vision : ¼ male, colorblind If a male inherits a sex-linked or X-linked trait, like hemophilia, which parent did he inherit it from? How do you know? Explain. 2. 1. He inherited it from his mother because his father gave him his Y chromosome and his mother gave him his X chromosomes. X-linked traits are located on the X chromosome. 10/21 Bio Warm Up 1. 2. 3. What is a karyotype and what are they used for? What causes chromosomal disorders? What is Turner’s syndrome? What is Klinefelter’s syndrome? 10/21 Bio Warm Up What is a karyotype and what are they used for? 1. A picture of all of the chromosomes in a cell. Karyotypes are used to diagnose chromosomal disorders. 1. What causes chromosomal disorders? 2. Nondisjunction – When homologous pairs or sister chromatids don’t separate correctly during meiosis. 1. 3. What is Turner’s syndrome? What is Klinefelter’s syndrome? 1. 2. Turner’s syndrome: XO Klinefelter’s syndrome: XXY
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