HPS Weekly National Influenza Report Summary of surveillance of influenza and other seasonal respiratory illnesses Week ending 1 April 2012 – week 13 1Summary • This report provides an update on influenza and other seasonal respiratory pathogen activity for the week ending 1 April 2012. For this season, we will provide detailed influenza update reports on a monthly basis with bulletin style weekly updates in the weeks in between. • This report contains summary epidemiological information on influenza-like illness (ILI), its severity and impact in the community and secondary care settings, and information on vaccine uptake estimates. • The GP consultation rate for influenza-like illness (ILI) has been calculated using a different method this season. Please refer to the technical document for further information on this. • Clinical influenza activity is low overall in Scotland and virological influenza activity was stable compared to the previous week. Levels of non-influenza seasonal viral pathogens are in line with expected levels. RSV activity is lower than at the same time last year. The number of Mycoplasma pneumoniae reports peaked towards the end of 2011, and has now decreased to levels comparable to the same time in previous years. 2 Community Surveillance – GP consultation rates and NHS24 calls • The proportion of cold/flu calls to NHS24 increased slightly this week but remained low overall and below expected levels at this time of year. Figure 1: GP consultation rates for ILI in Scotland; weekly rates per 100,000 population, week 40 2011 to week 13 2012 300 2010/11 weekly rate Rate per 100,000 population • In week 13, the GP consultation rate for ILI was low (11.6 per 100,000 population). This is a slight decrease on last week and within expected levels for this time of year, below the threshold for normal seasonal activity. 2011/12 weekly rate 250 200 150 100 50 0 40 42 44 46 48 50 52 2 4 Week 6 8 10 12 14 16 18 20 3 Severe Illness Surveillance • There was one laboratory confirmed case with severe infection requiring intensive care management due to an Influenza A/H3 infection reported to HPS last week. • A total of fourteen influenza infections requiring intensive care management have been reported to HPS since week 40 2011 (10 Influenza A/H3, 3 Influenza A (subtype unknown), 1 Influenza B). • Of these 14 cases, the majority of cases were over 45 years of age and had risk factors reported. Two individuals are known to have died. 4 Virological Surveillance (sentinel and non-sentinel) • In week 13, a total of 38 influenza infections (8 A/H3, 30 A (subtype unknown)) were reported through non-sentinel sources (ECOSS).The percentage positive for any influenza for non-sentinel samples was 4.4%.1 Three Influenza A/H3 infections were reported through the GP sentinel scheme (percentage positive: 3/27, 11.1%). Please note that the data for week 13 is provisional. • In general, the levels of non-influenza viral pathogens reported through the GP sentinel system and ECOSS were in line with expected seasonal levels. • The number of adenovirus infections reported through ECOSS has decreased since week 11 and was within levels seen at the same time last year. • The level of RSV and rhinovirus reports in ECOSS was lower than at the same time last year. • The number of Mycoplasma pneumoniae reports was stable over recent weeks and within levels seen at the same time last year. • Levels of Human metapneumovirus and parainfluenza reports were within levels seen at this time last year. 5Outbreaks • There were two confirmed closed setting Influenza A/H3 outbreaks in a nursing home and a hospital, reported to HPS in the last week. 6 Vaccine uptake • Estimated uptake in pregnant women without additional risk factors was lower than at this time last year; 39.6% (2012) vs 64.9% (2011). Uptake in pregnant women with additional risk factors was also lower than this time last year; 59.9% (2012) vs 74.8% (2011). Figure 2: Estimated seasonal influenza vaccine uptake in Scotland by risk group, week 40 to week 13 for season 2010/2011 and season 2011/2012 respectively 100 90 80 Vaccine uptake (%) • To week 13, provisional data showed that estimated vaccine uptake overall for Scotland was higher than at the same time last year; 76.2% (2012) vs 75.4% (2011) for those aged 65 years and above; 56.4% (2012) vs 56.1% (2011) for those under 65 years old in an atrisk group. 65 and over, 2011-12 65 and over, 2010-11 All risk groups, 2011-12 All risk groups, 2010-11 Pregnant/no risk 2011-12 Pregnant/no risk 2010-11 Pregnant/at risk 2011-12 Pregnant/at risk 2010-11 70 60 50 40 30 20 10 0 40 41 42 43 44 45 46 47 48 49 50 51 52 1 • Figure 2 shows the estimated cumulative vaccine uptake in Scotland by calendar week for the season 2011/2012, compared to the previous season. 2 3 4 5 6 7 8 9 10 11 12 13 Week • This is the final estimated seasonal influenza vaccine uptake for the 2011/2012 season. In the early summer, HPS will provide information from NSS Practitioner Services Division on the final validated vaccine uptake or usage. Such data is collated on the basis of claims for payment by General Practitioners to the end of the financial year 2011/2012. 7 International Situation • During week 12, clinical indicators of influenza activity in the UK remained relatively low and virological indicators of influenza activity declined slightly compared to the previous week [Datamart swab positivity: 12.9% (79/612), RCGP/RMN sentinel swab positivity 35.1% (13/37)]. 1 Percentage positive is derived from data from the Glasgow, Edinburgh and Aberdeen laboratories, for which denominator data is available. 5 April 2012 HPS Weekly National Influenza Report (Week ending 1 April 2012 – week 13) 2 • From week 40 to week 12, a total of 213 ICU/HDU severe acute respiratory illness cases were reported across the UK, with 22 (10.3%) resulting from Influenza A/H1N1 pdm09, 63 (29.6%) from Influenza A/H3N2, 116 from A (subtype unknown) and 12 (5.6%) from Influenza B. Twenty ICU/HDU influenza deaths across the UK have been reported (five A (unknown subtype), twelve A/H3N2 and three B). For the most up to date information on ICU/HDU cases in the UK please see the HPA report. • Across Europe, decreasing trends in influenza activity were reported by 21 countries in week 12 (fourteen of which have reported such trends for at least two consecutive weeks). Only 3 countries (Lithuania, Poland, Slovakia) reported increasing trends. The decrease in the proportion of influenzapositive sentinel specimens together with the growing number of countries reporting continuously decreasing trends in the incidence of ILI or ARI indicated that the epidemic peak has passed in most European countries. • Overall, influenza activity in the northern hemisphere was reported to be decreasing. In North America this influenza season was later than most other seasons, and whilst activity in some areas appeared to be peaking, increasing activity was still reported from some areas. Most countries in North Africa and the Middle East were reporting influenza activity at or near inter-seasonal levels. Influenza activity in northern China decreased slightly. • Most countries in the tropical zone reported low levels of influenza activity. • The most commonly detected virus type and subtype throughout most of the northern hemisphere temperate zone has been Influenza A/H3N2 to date, although the proportion of Influenza B has increased. In the later part of the season, increasing genetic and antigenic diversity in A/H3N2 viruses has been noted. In Mexico, Influenza A/H1N1 pdm09 was still the predominant virus circulating. China and surrounding countries were still reporting a predominance of Influenza B. © Health Protection Scotland 2012 Report produced by: HPS Flu Team 5 April 2012 Email: [email protected] HPS Weekly National Influenza Report (Week ending 1 April 2012 – week 13) 3
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