VOLTAIRE G. ORGANO, Ph.D. Associate Professor Department of Physical Sciences and Mathematics College of Arts and Sciences University of the Philippines - Manila Rizal Hall, Padre Faura Street, Ermita, Manila, Philippines 1000 Phone (632) 254-1881 Email : [email protected] RESEARCH INTERESTS Chemistry of macrocycles and calixarenes Supramolecular chemistry Molecular recognition Environmental chemistry EDUCATION 2002 – 2006 Ph.D. in Chemistry (December 2006) University of Texas at Arlington, Arlington, TX Major: Organic Chemistry Research Advisor: Prof. Dmitry M. Rudkevich Dissertation: Calix[4]arene-based Synthetic Nanotubes 1997 – 1999 Bachelor of Ministry (March 1999) Union Theological Seminary, Philippine Christian University Dasmariñas, Cavite (Philippines) 1989 – 1994 B.S. Chemistry (March 1994) Adamson University, Manila (Philippines) Summa Cum Laude Most Outstanding Chemistry Graduate Excellence in Chemistry Award Academic Excellence Award (1990-93) Campus Leadership Award (1991-92) University scholar WORK EXPERIENCE 2009 – present Associate Professor, University of the Philippines, Manila Currently teaching undergraduate Chemistry (General, Organic, Quantitative Analytical Chemistry), Natural Science (Chemistry portion), Advanced Analytical Chemistry, and Advanced Topics in Chemistry (Spectroscopy, Supramolecular Chemistry and Molecular Recognition). Serves as undergraduate thesis adviser to BS Biochemistry students, and Laboratory Coordinator 2007 – 2009 Postdoctoral Associate, Tufts University, Medford, Massachusetts, USA Supervisor: Prof. Elena V. Rybak-Akimova Characterized novel nickel(II) and iron(II) complexes using ESI-MS, IR and UV-Vis spectroscopies, and X-ray crystallography. Studied solution chemistry (metal coordination and catalysis) of novel nickel(II) macrocycles with varied pendant arms. Designed biomimetic oxidation catalysts using the biotinavidin technology. Synthesized biotinylated aminopyridine ligands, and characterized nickel(II) and iron(II) metal ligand-conjugates using ESI-MS, NMR, IR and UV-Vis spectroscopies. Studied catalytic activity of biotinylated iron(II) complex in avidin for aqueous oxidation of various substrates. Supervised undergraduate research projects in designing biomimetic oxidation catalysts and novel ligands for Positron Emission Tomography (PET) imaging. June – August 2006 Post-Baccalaureate Fellow, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA Supervisor: Martin W. Brechbiel, PhD Synthesized monoclonal antibody immunoconjugates for potential cancer treatment, and protein-chelate conjugates for magnetic resonance imaging (MRI). Analyzed pre- and post-modified proteins and antibodies using protein functional assays, size-exclusion chromatography and UV-Vis spectroscopy. 2005 – 2006 Graduate Research Assistant, University of Texas at Arlington, Arlington, Texas, USA Developed strategies for synthesizing calixarene-based synthetic nanotubes. Successfully determined its structure by spectroscopy and Xray crystallography. Studied supramolecular features of synthetic nanotubes which include encapsulation, stoichiometry, guest dynamics, kinetics and release using 1D and 2D NMR, UV-Vis, IR spectroscopies and molecular modeling. 2002 – 2004 Graduate Teaching Assistant, University of Texas at Arlington, Arlington, Texas, USA Handled undergraduate organic chemistry laboratory courses. Assisted with preparation and execution of experiments including lab techniques and safety guidelines. 1996 – 2002 Chemistry Instructor, University of the Philippines, Manila Taught undergraduate lecture and laboratory courses in General Chemistry, Organic Chemistry and Natural Science. Helped revise curricula and laboratory experiments in general and organic chemistry. 1995 – 1996 Research and Development Analyst/Chemist, Flexible Division, AR Packaging Corporation, Manila Responsible for development of new raw materials (plastic films, foils, paper, inks, adhesives, primers, etc.) for production of flexible packaging materials. This includes sampling for laboratory analysis and conducting process feasibility tests. LECTURE/LABORATORY DEVELOPMENT “Chemical Safety Training.” Developed a training program for freshmen on handling chemicals and proper chemical waste disposal in the General Chemistry laboratory classes. “Determination of pKa of Acid-Base Indicators.” Developed an experiment which incorporates spectroscopy (UV-Vis) and electrochemistry (pH meter) in determining pKa’s of several acid-base indicators. Adapted from J. Chem Educ. 1999, 76, 395398. “Structure Elucidation by NMR Spectroscopy.” Developed a dry lab experiment that helps students process, analyze and interpret NMR data using ACD/NMR Processor Academic Edition (freeware). “Homemade Spectrofluorometer.” Introduced a student project in Advanced Analytical Chemistry course for teaching basic fluorescence spectroscopy. Adapted from J. Chem. Educ. 2007, 84, 1308-1312. UNDERGRADUATE RESEARCH PROJECTS “Colorimetric Dection of Organic Compounds Using Pigments Extracted from the Flowers of Anthurium andreanum.” Santos, Maria Eloisa R., Organo, Voltaire G. (Thesis defended October 2013). “Cobalamin as Colorimetric Sensor for Gas Pollutants.” Pabilane, Alma L., Organo, Voltaire G. (Thesis defended April 2013). “Colorimetric Anion Sensors from Flower Pigments of Agapanthus praecox, Anthurium andreanum and Dianthus caryophyllus.” Galingana, Maynard O., Organo, Voltaire G. (Thesis defended March 2013). “Colorimetric Recognition of Pollutant Gases Using Pigments Extracted from the Flowers of Agapanthus praecox, Anthurium andreanum, and Dianthus caryophyllus.” Abuel, Rachelle Jenine D., Organo, Voltaire G. (Thesis defended March 2013). “Biginelli Dihydropyrimidine Synthesis Via a Protic Deep Eutectic Solvent as Green Reaction Medium.” Duro, Marlon Vincent V., Villarante, Nelson R., Organo, Voltaire G., Robidillo, Christopher T. (Thesis defended November 2012). “pKa Determination of Free and Immobilized Acid-Base Indicators Extracted from Agpanthus praecox, Anthurium andreanum, and Dianthus caryophyllus.” Narciso, Karina Sophia M., Organo, Voltaire G. (Thesis defended March 2012). Best Thesis Award. “Cu(II)-Substituted Chlorophyll As Gas Sensor For Pollutants.” Espiritu, Kevin E., Organo, Voltaire G. (Thesis defended March 2012). “Encapsulated Iron Compounds as Delivery Systems for Salt Fortification.” Gajigan, Adrian P., Organo, Voltaire G. (Thesis defended March 2012). “Synthesis of Supramolecular Structures from Lysine and Arginine Using CO2 as Cross-linker.” Lesigues, Faith Hope G., Organo, Voltaire G. (Thesis defended June 2011). “Chlorophyll as Sensor for Gas Pollutants.” Bernardo, May Kristine, Organo, Voltaire G. (Thesis defended June 2011). “Nutrient Studies and Growth Response Curves of VAM and Non-VAM Inocculated Onions (Allium cepa) in Two Soil Types with Increasing Amount of NPK.” Zaldua, Vina Zarina M., Organo, Voltaire G. (Thesis defended April 2011). “Decolorization of Azo Dyes by Peroxidase Derived from Squash (Cucurbita maxima Duschesne) Waste.” Parungao, Nico Angelo C., Organo, Voltaire G. (Thesis defended March 2011). “Effect of Ultraviolet Irradiation on the Leaves and Flowers of Tobago Chrysanthemums.” Gumabon, Kevin Elissandro C, Organo, VG. (Thesis defended March 2011). “Mn(II)-Catalyzed Oxidation of Polychlorinated Biphenyls (PCBs) with Hydrogen Peroxide.” Perez, Ma. Isabel O., Organo, Voltaire G. (Thesis defended May 2010). “The Influence of the Energies of HOMO and LUMO, the Size of the Substituents at C2 and C4 and Orientation of the Alkyl Chain on the Psychoactivity of Cannabinoid Compounds.” Castro, Mary Cherwyn L., Organo, Voltaire G. (Thesis defended May 2010). “Bioaccumulation of Heavy Metals in Tilapia (Oreochromis niloticus) from Marilao, Binangonan and Batangas.” Guaring II, Rogelio V., Organo, Voltaire G. (Thesis defended March 2010). PUBLICATIONS Book Chapter: Rudkevich, Dmitry M.; Organo, Voltaire G. “Synthetic Nanotubes from Calixarenes.” In Organic Nanostructures; Atwood, J. L., Steed, J. W., Eds.; WileyVCH: Germany, 2008, 97-109. Journal Publications: (1) Bernardo, May Kristine O., Organo, Voltaire G. “Chlorophyll as a simple, inexpensive and environment-friendly colorimetric indicator for NO2 gas.” Oriental Journal of Chemistry 2014, 30(2). (In press). (2) Billones, Junie B., Carrillo, Maria Constancia O., Organo, Voltaire G., Macalino, Stephanie Joy Y., Emnacen, Inno A., Sy, Jamie Bernadette A. “Virtual Screening against Mycobacterium tuberculosis Lipoate Protein Ligase B (MtbLipB) and In Silico ADMET Evaluation of Top Hits.” Oriental Journal of Chemistry 2013, 29(4), 1457-1468. (3) Organo, Voltaire G.; Filatov, Alexander S.; Quartararo, Justin S.; Friedman, Zachary M.; Rybak-Akimova, Elena V. “Nickel(II) complexes of monofunctionalized pyridine-azamacrocycles: Synthesis, structures, pendant arm “on-off” coordination equilibria, and peroxidase-like activity.” Inorganic Chemistry 2009, 48(17), 84568468. (4) Organo, Voltaire G.; Ye, Wanhua; Agarwal, Prakhar K.; Rybak-Akimova, Elena V. “Biotinylation of aminopyridine-based macrocycles and metallomacrocycles, and inclusion of biotinylated iron(II) complex in avidin.” Journal of Inclusion Phenomena and Macrocyclic Chemistry 2009, 64, 15-21. (5) Organo, Voltaire G.; Rudkevich, Dmitry M. “Emerging host-guest chemistry of synthetic nanotubes.” Chemical Communications 2007, 3891-3899 (Review/Feature article). (6) Wanigasekara, Eranda; Leontiev, Alexander V.; Organo, Voltaire G.; Rudkevich, Dmitry M. “Supramolecular, calixarene-based complexes that release NO gas.” European Journal of Organic Chemistry 2007, 2254-2256. (7) Organo, Voltaire G.; Sgarlata, Valentina; Firouzbakht, Farhood; Rudkevich, Dmitry M. “Long synthetic nanotubes from calix[4]arenes.” Chemistry - A European Journal 2007, 13, 4014-4023. (8) Sgarlata, Valentina; Organo, Voltaire G.; Rudkevich, Dmitry M. “A procedure for filling calixarene nanotubes.” Chemical Communications 2005, 5630-5632. Among the Top 10 most accessed article in October 2005 (9) Organo, Voltaire G.; Leontiev, Alexander V.; Sgarlata, Valentina; Dias, Rasika H.V.; Rudkevich, Dmitry M. “Supramolecular features of synthetic nanotubes.” Angewandte Chemie International Edition 2005, 44, 3043-3047. Featured in the news article, “Fresh interest in non-graphite nanotubes,” Chemistry World (published by the Royal Society of Chemistry), 2005, 2(6). (10) Rudkevich, Dmitry M.; Kang, Yanlong; Leontiev, Alexander V.; Organo, Voltaire G.; Zyryanov, Grigory V. “Molecular containers for NOx gases.” Supramolecular Chemistry, 2005, 17, 93-99. PRESENTATIONS (1) Organo, VG, Billones, JB., Carrillo, MCO., Macalino, SJY., Emnacen, IA., Sy, JBA. Structure-Based Pharmacophore Screening, Molecular Docking, And In Silico Toxicity Evaluation Of Compounds Againast Mycobacterium Tuberculosis L,D Transpeptidase 2 (LdtMt2). Drug Discovery Chemistry, Hilton Resort and Spa, San Diego, CA (USA), April 23-25, 2014. (2) Abuel RJD, Organo VG. Colorimetric Recognition of Pollutant Gases Using Pigments Extracted from the Flowers of Agapanthus praecox, Anthurium andreanum, and Dianthus caryophyllus. 28th Philippine Chemistry Congress, Siliman University, Dumaguete City, April 10-12, 2013. (3) Galingana MO, Organo, VG. Colorimetric Anion Sensors from Flower Pigments of Agapanthus praecox, Anthurium andreanun, and Dianthus caryophyllus. 28th Philippine Chemistry Congress, Siliman University, Dumaguete City, April 10-12, 2013. (4) Duro MV, Olaguerra RM, Villarante NR, Robidillo C, Organo VG, Arco S, Zhang CP. Designer Solvents in Organic Synthesis. 28th Philippine Chemistry Congress, Siliman University, Dumaguete City, April 10-12, 2013. (5) Billones JB, Carrillo, MC, Organo VG, Macalino SJ, Emnacen I. Structure-Based Pharmacophore Screening and Molecular Docking of Compounds to M. tuberculosis Lipoate Protein Ligase B (LipB). 28th Philippine Chemistry Congress, Siliman University, Dumaguete City, April 10-12, 2013. (6) Bernardo MK, Organo VG. Chlorophyll as Sensor for NO2 Gas. 6th Pure and Applied Chemistry International Conference (PACCON 2012), Empress Convention Center, Chiang Mai, Thailand, January 11-13, 2012. (7) Safety First! – Best Practices of Doing Chemistry in the Classroom. Plenary Speaker. 50th Philippine Association of Chemistry Teachers, Inc. (PACT) National Convention, University of Santo Tomas, Espana Blvd., Manila, October 28, 2011. (8) Laboratory Safety. Workshop Facilitator. 50th Philippine Association of Chemistry Teachers, Inc. (PACT) National Convention, University of Santo Tomas, Espana Blvd., Manila, October 28, 2011. (9) My Chemistry Journey: From Student to Scientist. Career Forum and Workshop, Adamson University, February 19, 2011. (10) Proper Storage of Chemicals and Disposal of Laboratory Wastes. Plenary speaker. 51st Seminar & Annual Convention, Philippine Alliance of Laboratory Equipment Users (PALEU), Makati Sports Club, Leviste St., Salcedo Village, Makati City, November 26, 2010. (11) Host-Guest Chemistry of Gases. Biochemistry Society Week 2010, NTTC-HP Auditorium, University of the Philippines, Manila, September 15, 2010. (12) NOx Chemistry: From Sensing to Fixation. Mugs and Cups Lecture Series, College of Arts and Sciences, University of the Philippines, Manila. July 21, 2010. (13) Chemical Safety and Security Training Seminar. College of Arts and Sciences, University of the Philippines, Manila, June 16, 2010. (14) Organo VG, Filatov AS, Quartararo JS, Friedman ZM, Rybak-Akimova EV. Nickel(II) Complexes of Pyridine-Azamacrocycles (PyMACs): Synthesis, Structures, Pendant Arm “On-Off” Coordination Equilibria, and Peroxidase-like Activity. 25th Philippine Chemistry Congress, Subic, Zambales, Philippines, April 810, 2010. (15) In the Company of Rings: A Chemist’s Journey. Adamson University, Manila, September 23, 2009. (16) Organo VG, Leontiev AV, Sgarlata V, Rudkevich DM. Calix[4]arene Synthetic Nanotubes. 10th Eurasia Conference on Chemical Sciences, Manila, Philippines, January 7-11, 2008. (17) Exploring the Supramolecular Chemistry of Synthetic Nanotubes. Adamson University, Manila, January 15, 2008. (18) Calix[4]arene-based Synthetic Nanotubes. Postdoc Day 2007, Tufts University, Medford, MA, August 13, 2007. (19) Organo VG, Leontiev AV, Sgarlata V, Rudkevich DM. Synthetic Nanotubes. Research Day ’05, University of Texas at Arlington, Arlington, TX, October 26, 2005. (20) Organo VG, Leontiev AV, Sgarlata V, Rudkevich DM. Calix[4]arene-based Synthetic Nanotubes. 38th Annual Meeting-in-Miniature, American Chemical Society, Dallas-Ft. Worth Section. Arlington, TX, April 30, 2005. (21) Calix[4]arene-based Synthetic Nanotubes. University of the Philippines, Manila, Philippines, July 22, 2004. (22) Organo VG, Leontiev AV, Zyryanov GV, Rudkevich DM. Synthetic Nanotubes: New Molecular Containers for NO2/N2O4 Fixation. 227th ACS National Meeting, Anaheim, CA. March 28-April 1, 2004. SEMINARS/WORKSHOPS ATTENDED (1) Drug Discovery Chemistry: Macrocyclic and Constrained Peptides. Sponsored by Cambridge Healthtech Institute. Hilton Resort and Spa, San Diego, CA (USA), April 23-25, 2014. (2) Ethics in Research Seminar for Thesis Advisers. Sponsored by Manila Studies Program, College of Arts and Sciences, University of the Philippines, Manila. Little Theater, CAS, UP Manila. November 7, 2012. (3) Permits and Licenses: Updates on Regulatory Requirements of Procuring Chemicals and Waste Disposal. Sponsored by Merck, Inc. Marriott Hotel, Newport City Complex, Pasay City. August 3, 2012. (4) Revisiting the Role of UP Academics as Public Intellectuals (Faculty Conference). Organized by the College of Arts and Sciences, University of the Philippines-Manila. City State Hotel, Ermita, Manila. June 29, 2012. (5) Safety in the Laboratory. Conducted by Merck, Inc. Little Theater, College of Arts and Sciences, University of the Philippines, Manila. November 14, 2011. (6) Scanning Probe Microscopy and Nanocharacterization. Sponsored by Shimadzu Philippines Corporation. NTTC-HP Auditorium, University of the Philippines, Manila. August 17, 2011. (7) Chemical Safety and Security Officer’s Training. Organized and conducted by the Chemical Security Engagement Program and Sandia National Laboratories (USA), Hotel Equatorial, Bangi-Putrajaya, Malaysia. May 31-June 4, 2010. (8) Instructional Design. Organized by the Committee on Instruction and the Office of the Vice Chancellor for Academic Affairs, NTTC-HP Auditorium, University of the Philippines, Manila. May 19, 2010. (9) Best Practices in the Teaching of Chemistry. Organized by the Committee on Instruction and the Department of Physical Sciences and Mathematics, College of Arts and Sciences, University of the Philippines, Manila, September 9, 2009. (10) Chemistry for the New Millennium. 16th Philippine Chemistry Congress, Philippine Federation of Chemistry Societies, Manila Hotel, Manila. May 22-24, 2000. (11) Innovative Teaching for the Next Millennium. Organized by College of Arts and Sciences, University of the Philippines-Manila, Christian Development Center, Tagaytay City. May 20-21, 1999. (12) Chemistry of Consumer Products: Truth in Consumer Labeling. Organized by the Kapisanang Kimika ng Pilipinas, EDSA Shangri-La Hotel, Mandaluyong City. February 24, 1999. (13) How To Develop, Validate, and Troubleshoot Capillary GC Methods. Organized by the Bureau of Plant Industry, Integrated Chemists of the Philippines and the Kapisanang Kimika sa Pilipinas, BPI, Quezon City. January 28-30, 1998. (14) Quality Education System. Quality Improvement Process, AR Packaging Corporation. Completed September 22, 1995. (15) Food Quality Assessment. Organized by the Adamson University Chemistry Alumni Association and Department of Chemistry, OZ-AVR, Adamson University, Manila. February 20, 1995. AWARDS Outstanding Teacher. Given by College of Arts and Sciences, University of the Philippines-Manila, October 11, 2013 Outstanding Alumnus. Given by Adamson University Alumni Association, Inc., Adamson University, February 7, 2013 Outstanding Alumnus. Given by Adamson University Chemistry Alumni Association, Inc., Adamson University, April 2, 2011. Faculty Development Award. Given by the University of the Philippines, Manila, April 8, 2010. International Publication Award. Given by the Office of the Vice President for Academic Affairs, University of the Philippines, 2009. Diamond Jubilee Faculty Grant. Given by University of the Philippines, Manila, July 1, 2009-June 30, 2000. GRANTS Computer-Aided Discovery of Compounds for the Treatment of Tuberculosis in the Philippines. Junie B. Billones, Maria Constancia O. Carillo, Voltaire G. Organo. Funded under Emerging Interdisciplinary Research (EIDR) Program Cycle 1, University of the Philippines System, ~Php 10M for 2012-2015. Colorimetric Sensor Array Based on Plant Pigments for the Detection of Gas Pollutants. Funded under Creative and Research Scholarship Program, University of the Philippines System, Php 301K for 2012-2013. AFFILIATION Scientific/Academic Membership American Chemical Society Philippine Association of Chemistry Teachers Organic Chemistry Teachers Association (Philippines) Integrated Chemists in the Philippines Religious Involvement Ellinwood-Malate Church (Manila, Philippines) Church Elder (2013-2015) Coordinator, Choir Coordinating Council (2011-2014) President, Chancel Choir (2011-2014) Adviser, Artists for Christian Teaching and Service (ACTS) 29 Church Deacon (2002) Coordinator, Youth Coordinating Council (1998-1999) Coordinator, Youth Sunday School (1998-2002) Sunday School Facilitator, Senior High School (1993-2002) Vice-Coordinator, Youth Coordinating Council (1994-1995) Christian Education Commissioner (1996-1997, 1992-1993) Cosmopolitan United Church of Christ (Carrollton, TX) Vice-Moderator, Church Council (2005-2006) Member, Stewardship Committee (2003-2004) Member, Covenant Choir (2002-2006) Christian Youth Fellowship, United Church of Christ in the Philippines Coordinator, Manila Chapter, Greater Manila Conference (19941995) OTHER EXTENSION SERVICES Member, Scientific Paper Committee. 28th Philippine Chemistry Congress, Siliman University, Dumaguete City, Negros Oriental, 10-12 April 2013. Judge, Le Chimie Quiz Bee. Sponsored by University of the Philippines Biochemistry Society (UP BCS), NTTC-HP, University of the Philippines, Manila, September 12, 2012. Guest Speaker, 1st Academic Year Fellowship, State Varsity Christian Fellowship, University of the Philippines, Manila, 05 July 2011. Chair, Special Committee for the International Year of Chemistry Celebration, Adamson University Alumni Association, 2010-2011. Chair, Opening Program and Science Symposia, Science Week 2011, Department of Physical Sciences and Mathematics, College of Arts and Sciences, University of the Philippines, Manila. Chair, Qwizzardy Committee, Science Week 2010, Department of Physical Sciences and Mathematics, College of Arts and Sciences, University of the Philippines, Manila. Laboratory Coordinator, Department of Physical Sciences and Mathematics, University of the Philippines, Manila, 2010-present. Member, CAS Sub-Committee on Laboratory Assessment, College of Arts and Sciences, University of the Philippines, Manila, 2009. Camp Adviser, Ellinwood-Malate Church Children’s Camp 2002, Paenaan Camping Farm, Antipolo City. April 16-20, 2002. Camp Director, Ellinwood-Malate Church Children’s Camp 2001 (Bataan Techno Park, Morong, Bataan. April 24-27, 2001), Ellinwood-Malate Church Youth Camp 1999 (Jabez Campsite, Dasmariñas, Cavite. April 5-9, 1999). Camp Counselor, GMC-CYF Summer Camp. Organized by the Greater Manila Conference Christian Youth Fellowship, Talisay, Batangas. May 26, 1999. Faculty Tutor, Tutorial Services Program. Organized by the Learning Resource Center, Bulwagang Joaquin Gonzales, University of the Philippines, Manila. First Semester 2001-2002. Facilitator/Trainor, Teacher’s Training Program. Training of local high school chemistry/science teachers on best practices in teaching chemistry. Organized by the Ugnayan ng Pahinungod, University of the PhilippinesManila, Zamboanga del Norte Provincial DECS Division, Dipolog City, Zamboanga del Norte. April 4-18, 1997. Trainor, 1997 Affirmative Action Program. Training of student volunteers for peer tutoring in chemistry. Organized by Ugnayan ng Pahinungod, University of the Philippines-Manila, Philippine General Hospital, Manila. March 18, 1997.
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