in the next 30 years the number of people needing care will triple in the Nordic region. longer life expectancy, new medicines and better treatments will improve QUALITY OF LIFE and will pose Nordi c healthcare one essential question. Who’s going to pay? health 3.0 Includes a summary of the 2008 If year start tomorrow’s health and healthcare who’s going to pay? H ealthcare is one of society’s most important issues. The political decisions taken, discoveries made and new types of treatments developed, all have an immediate bearing on our lives. Enormous advances have been made in these areas over the past 100 years. Life expectancy in the Nordic region has increased by more than 20 years. A long list of deadly or very serious diseases such as smallpox, polio and diphtheria have been eradicated. And developments continue. New medicines and treatments mean that the prospects for surviving cancer and other major widespread diseases look good for the future. nnn At the same time health has become a difficult political issue. In 30 years the number of elderly who may need healthcare will have increased dramatically in the Nordic countries. At the same time research is revolutionizing care and medications. This means increased costs. Public sector resources will not be able to cover everything that is possible to achieve. This will force us to make serious ethical decisions. Who will have the right to new, often expensive, treatments? And who will be forced to forgo them? ers compensation insurance and health insurance. I believe we are witnessing only the beginning of this development. In 20 or 30 years, a significantly larger part of healthcare will in all probability be financed through private or employer-purchased insurance. Some feel that this is a disturbing development and believe that it will lead to a society that favours those with most resources. Others, such as I, look on private and employer-related solutions as a way to create better healthcare for all. And it is in itself exciting that so many seem interested in a discussion about using our prosperity for better health rather than just more material things. nnn The debate about tomorrow’s healthcare has already begun, but it needs to be intensified and broadened, and the aim of this publication is to contribute to that. Let’s start now. Torbjörn Magnusson, CEO If P&C nnn One central issue is: What will society have the means and the resolve to take responsibility for in the future, and what must we pay for ourselves? The trend is toward more private solutions. If and other insurance companies already complement public healthcare in some areas, e.g. through children’s insurance, work- PS. At the end of this publication there is a section that presents If and our result for 2008. Be sure not to miss it! photo: thron ullberg contents chapter 1 new disease landscapes and an increased life expectancy will create different healthcare needs, research will provide new methods and medicines. an overstretched health sector finds it increasingly difficult to make ends meet. what will this cost you? how we’ll fall ill the next generation’s ill health ������������������������������� 6 n four diseases and their trends ������������������������������������ 9 n the future will make us healthier – and less well� ���������������������������������������������������������������������������������� 10 n chapter 2 how we’ll get help chapter 3 0 who will pay? at the sharp end of research ���������������������������������������� 14 n s cience fiction or reality? � ��������������������������������������������� 18 n n p riorities in focus as the north ages ������������������������������������������������������������������������ 22 n 2 4 replies: who pays for tomorrow’s healthcare?����������������������������������������������������� 26 4 chapter 1 how we’ll 2009 The image shows a blood clot that could lead to a stroke or heart attack. Cardiovascular diseases are the most common cause of death today. But the graph points steadily downwards. In Sweden the risk of dying of coronary artery disease dropped by 40 per cent between 1987 and 2002. Preventive efforts and better cardiac emergency care are the reasons. 5 fall ill 2025 Cancer is an increasingly common disease. The number of new cancer cases is rising by 1 to 1.5 per cent per annum throughout the Nordic region. Nothing indicates that the upward trend will fall off. In 2025 around 700 in every 100,000 Nordic citizens will fall ill with cancer. The image shows a breast cancer cell, i.e. a small part of a malign cancer tumour. Breast cancer is the most common form of cancer among women. how we’ll fall ill chapter 1 6 will we grow old, get sick and die the same way our forefathers did? Hardly. New diseases are on the increase, others on the decline. you will very likely be older, healthier and work longer than your parents. the next generation’s ill health B etter medicines, vaccines and living standards have helped the Nordic citizens increase their longevity by around two years every decade over the past century. This trend shows no signs of falling off. The very oldest will be older yet, and more and more of us will experience old age. The Nordic countries will have more elderly people, and more of them will be healthy. Statistics Norway has calculated that the “Senior Boom” will begin around 2013, and as early as 2060 the number of people 67 years old or older will be around double that of today. In Norway, the proportion of people over 80 will increase from around five per cent to nine per cent – from 213,000 to over 440,000 people. According to the report “Take part; take decisions!” prepared by the Swedish National Institute of Public Health, around 44 per cent of Swedes will be 50 or older by 2025 – either as pensioners or on their way to pension. By 2050 as much as half the Swedish population will be 50 or older, and those leaving working life will outnumber those entering it. Most likely fewer children will be born, which will result in fewer employed people to provide for pensioners. The “Senior Boom” will not just sweep across Norway and Sweden, but the rest of the Nordic region and Europe too. And so our part of the world will have a new human resource. The Copenhagen Institute for Futures Studies (IFF) in Denmark has prepared a report entitled “Behind the Facade”. In it tomorrow’s text: Vigdis Askjem Dahl seniors are characterized as everyman romantics, backpacking pensioners, scientific acrobats and local heroes with time and money to spare. Future centenarians will be like today’s eighty-year-olds, and eighty will be the new sixty. In other words, there will soon be many more healthy old people enjoying meaningful lives. “Older people will probably be working longer as a shortage of manpower will lead to an increase in pensionable age in many countries. And what’s more, they will have fewer strain injuries due to the less physically demanding nature of their work. They will quite simply last longer in the job market,” says Kristina Laksáfoss Søgaard, project manager at IFF. In her opinion, old people of the future will also be better off financially and thus have more opportunities for spending money. They will have much better prospects of meeting their needs and living out their dreams, depending on their interests. New disease landscapes A girl born today can expect to live until she is at least 82 and a newborn boy until he is 78. But it was not always like this. “125 years ago Norway 7 was a poor corner of Europe. Bad diet and inadequate hygiene allowed poverty-related illnesses such as tuberculosis and leprosy to flourish,” says Geir SteneLarsen, Director of the Norwegian National Institute of Public Health. Infant mortality was as high as 10 per cent and in 1880 epidemics of various kinds of infectious diseases were dominant and widespread. Of these, tuberculosis, smallpox and leprosy were the most feared, surrounded by taboo and received the greatest attention. It was not until various antibiotics arrived on the scene in the 1940s and 50s, and child vaccination programmes began in the 50s, that we seriously came to grips with the many deadly infectious diseases – diseases we never give a second thought to today. Stene-Larsen tells us that since World War II it is cardiovascular diseases and cancer – and latterly also type 2 diabetes and COPD (chronic obstructive pulmonary disease) – that constitute the biggest widespread diseases. Since 1950 our longevity has increased by almost ten years, but at the same time illnesses such as cardiovascular disease and cancer have become ever more common. “Something will kill us in the end, and cardiovascular diseases are still a common cause of death, but now at a later age. It is possible that these will increase all the more if the population continues to put on weight. Today, the obesity epidemic affects rich and poor countries alike, but widespread illnesses such as cancer and cardiovascular diseases are the most common causes of death,” says Stene-Larsen. He feels that it is difficult to foresee the type of illnesses that will dominate in the future, but believes that we will continue to suffer from the most widespread “western” diseases. Also, mental disorders will probably receive more attention. “On average, one or two new infectious diseases have shown up every year for the past 30 to 40 years, most of these in poor countries. But illnesses such as legionnaire’s disease and HIV/AIDS have also affected rich countries,” says Stene-Larsen, and points out that it is not inconceivable for infectious diseases to once again be the most serious endemic diseases in rich countries. The difference between then and 9 factors that affect your health 1 Exercise In order for us to have the energy for work and to protect ourselves against illness, we need to be in good shape. Stamina is important for sustaining good health, and it also guards against strain injuries, cardiovascular disease and type 2 diabetes. The COPD picture. Airways become swollen, tight and partially obstructed leading to severe breathing difficulties. It has become one of the major widespread diseases since the Second World War. cardiovascular diseases are still a common cause of death, but now at a later age Kristina Laksáfoss Søgaard, project manager at IFF in Denmark. Geir Stene-Larsen, Director of the Norwegian National Institute of Public Health. now, and between rich and poor, is that in the Nordic region we live in welfare societies with world-class hospitals and care. Public care dominates However, Kristina Laksáfoss Søgaard at IFF is of the opinion that there will be much more emphasis on service in hospitals and healthcare than today, and that the elderly will place ever greater demands on such service. “Because the elderly of the future will enjoy better personal finances they will also have the opportunity to buy healthcare to a far greater extent than is usual today. And it is unlikely they will be content with the standards the public sector has to offer,” says Søgaard. 2 diet What we eat affects our health, but how? The experts disagree. Some say we should not eat fatty foods, while others say that fat is just what the body needs. 3 sex Men who ejaculate at least twice a week have a 50 per cent lower risk of premature death than those who have an orgasm once a month. According to a German study, couples who kiss each other every morning live five years longer than others. 4 education Education has a great influence on our future living conditions, standard of living, finances and lifestyle. A study has shown that ambitious men in the 40 to 50 age group suffer from Alzheimer’s to a lesser extent than those who remained at the same place of work for the larger part of their lives. chapter 1 8 how we’ll fall ill Even today we can see that private healthcare has achieved greater significance in the Nordic countries. “Dental care is one example of this. And pharmacies have been privatized in every Nordic country except Sweden. Now the Swedish pharmaceutical market is also being de-regulated,” says Mika Gissler, professor at the Nordic School of Public Health in Sweden and Director of Development at the Finnish Research and Development Centre for Health and Welfare (Stakes). But even though private healthcare has grown, it is still public healthcare that dominates. Gissler tells us that the provision of healthcare in the public sector looks different depending on which Nordic country a patient lives in. Patients have no freedom of choice in Finland, while in Sweden they are free to choose any hospital in their county. There is also freedom of choice in Norway, and in Denmark a patient may even select a hospital abroad when waiting lists are longer than two months. Today, the Swedish, Norwegian and Danish public sectors cover 82 to 84 per cent of all costs pertaining to healthcare. In Finland it is a little lower – there the state pays 76 per cent of costs, and it is also the Nordic country where the personal contribution is highest. Healthcare is largely de-centralized, i.e. divided into regions or municipalities. “In Finland it is chiefly the municipalities that are responsible for healthcare, especially primary care. In the smallest municipalities there are only a couple of hundred inhabitants, so it really is a case of local democracy, for better or for worse,” says Gissler. He says that the Finnish system will change in time, and that a re-organization into larger health districts is at the planning stage. In Denmark and Sweden, regions and counties have a strong position, while in Norway it is the state that is responsible for hospital care via regional health companies. patients have no freedom of choice in finland, while in sweden they are free to choose any hospital they like Vaccine development sluggish At the same time as the hospital structure is changing, new medicines are being developed. For example, the World health Organization has a long list of infectious diseases they want to develop vaccines for. 6 5 sleep When we get too little sleep it affects our mood and quality of life. Many traffic accidents and accidents at work are probably caused by a lack of sleep. Genetic inheritance If one of your parents has a predisposition for an illness, there is a 50 per cent probability that you and your siblings inherited it. But not everyone who inherits a predisposition necessarily develops the illness. 7 alcohol and smoking Beer, wine and spirits contain quite a few calories. Additionally, it is a fact that too much alcohol can have a very detrimental effect on health. And it’s no news that smoking causes lung cancer, heart disease, emphysema and other serious illnesses. However, in recent times the pharmaceutical industry has been hesitant to invest large sums in the development of new vaccines, the reason being that vaccines provide lower profits than medicines. Furthermore, there have been a number of legal actions in which pharmaceutical companies have been ordered to pay large sums in compensation to patients who have suffered side effects from vaccines. “Therefore developments proceed more slowly than we had hoped. But despite this, new, useful vaccines arrive all the time. A vaccine against the human papilloma virus is the latest to be used in Norway. Vaccinations begin in the autumn of 2009 and will include all girls in the 11 to 12 age group. It is a vaccine that protects against cervical cancer,” says Geir Stene-Larsen. Will pharmaceutical developments lead to a further increase in longevity? “Yes, we believe so. In particular advances in the treatment of cancer will prevent many premature deaths. But also in a number of other areas there are new medicines and new treatment methods that prolong life. More and more of us will live to be a hundred years old. Calculations show that women born in 2060 will have a life expectancy of 87 to 93 years, and men 83 to 88 years. n 8 happiness Mirth and merriment lengthen life! And according to humour researcher Professor Sven Svebak this is absolutely true – a sense of humour makes life easier, helps improve health and can affect longevity. 9 globalization Contagion follows mankind on his travels. There is no virus, bacterium or radioactive and chemical pollutant that respects national boundaries. From a health standpoint, the Nordic region is ever more dependent on international cooperation. 2025: cancer increases but hearts get better fewer cardiovascular patients, the same unhappiness and more cancer cases. In the worst case, tuberculosis makes a comeback. This is the health situation in 2025 say the experts. by: Madeleine Bäck cancer Thor Stenbeck carries out the world’s first successful radiotherapy in Stockholm. This is only three years after the discovery of X-rays. 1899 Understanding of cancer development progresses. A great step forward is the discovery of oncogenes, important for a cancer’s growth, and tumour suppressor genes that have the opposite effect. 1980s The number of cancer cases in Denmark is greater than in the other Nordic countries. Since the year 2000 the number of cancer patients in Norway has also increased. Unhealthy lifestyles are thought to be the reason, above all smoking in Denmark. 2000 The number of new cancer cases per year is rising by 1 to 1.5 per cent across the Nordic countries. Nothing indicates this upward trend will fall off. In 2025 around 700 per 100,000 Nordic citizens will fall ill with cancer. 2025 Cardiovascular and strokes The risk of falling ill and dying of cardiovascular disease fell dramatically from the end of the 1980s. There are several theories regarding the cause. Two are healthier lifestyles and reduced smoking. 1980s The number of deaths from ischaemic heart disease has halved since the beginning of the 60s in the Nordic region, for both men and women. In Sweden the risk of dying from coronary artery disease dropped by 40% just in the period from 1987 to 2002. 1990s In contrast to other arterial diseases, strokes have only dropped marginally. However, the risk of death one year from a stroke shows a reduction. From 47% in 1987 to 39% in 2001. 2001 “Hopefully the scenario will be that heart and arterial diseases and mortality will continue to fall. Our lifestyles and preventive treatments are decisive factors.” Urban Janlert, Umeå University, Sweden. 2025 mental illness “It’s a bit of a myth that mental illness is on the rise in Nordic countries. Finnish data shows that the number of patients is around 10% of the population since the 1980s.” Kristian Wahlbeck, Professor of Psychiatry, Mental Health Group, Stakes, Finland. 1980 The 10% figure still applies. The exception is in children and the young where we see an increase in mental illness in that more and more of them receive antidepressive treatment. 1990 Mental illness costs society large sums every year. The cost of depression alone is the equivalent of 2,300 Swedish crowns per year per person in Europe when all the indirect costs such as unemployment, reduced capacity for work and criminality are included. Scientists believe that the number of mentally ill will be the same in 30 years, i.e. 10% of the Nordic population. 2000 2025 The threat in Sweden seems to be under control and vaccination ends. Finland takes time to catch up because of difficulties stemming from the civil war and World War II. Today the country is ahead and the Nordic region has the lowest number of cases in the world. “The problem with antibiotic-resistant TB in the Baltic states and Russia, together with immigration to the Nordic region, may cause a rise in TB. However, new vaccines and treatments are being developed, which may slow up this development.” Gunnar Boman, Uppsala University, Sweden. tuberculosis The disease accounts for 25% of the total mortality in Sweden. The first sanatoria for isolated treatment of tuberculosis patients are built. 1900 Universal vaccination against the tubercle bacterium is introduced using the so-called BCG vaccine still in use today. 1940s 1975 2025 Sources: Wiman, Beskow, Swedish Medical Association Journal no. 15–16, vol. 103, 2006/Swedish Healthcare Advice Centre, Swedish Institute for Infectious Disease Control/Swedish Radio Science Association/ Swedish Cancer Society Periodical, no. 4, 2007/NOMESCO – Health Statistics in the Nordic Countries, 2006/Tuori, Gissler, Wahlbeck “Mental health in the nordic countries”, STAKES 2006/National Institute of Public Health, Denmark, Public Health Report 2007/Swedish National Board of Health and Welfare, Public Health Report 2005/Urban Janlert, Professor of Epidemiology and Public Health Sciences at the Institute for Public Health and Clinical Medicine, Umeå University, Sweden/Gunnar Boman, Professor Emeritus in Pulmonary Medicine and Allergology, Uppsala University/Carsten Rose, Clinical Director, Oncological Clinic, University Hospital, Lund. 9 chapter 1 10 how we’ll fall ill Anders Sandberg, Philosophy Researcher at Oxford university “The future will make us healthier – and less well” Tomorrow’s technology will increase our chances of diagnosing and curing diseases. At the same time it will change our view of ill health. In the future it will be considered an “illness” to be forgetful or to have a low stress threshold, asserts Anders Sandberg, philosophy researcher at Oxford. I magine that you go to the doctor to check up on a stubborn autumn cough. Instead of getting the diagnosis “chest cold” you leave with a report stating exactly which virus you have, together with an analysis of exactly how this virus will affect your own, unique, medical constitution. And incidentally, you also find out you have a nascent brain tumour and that you carry a genetic mutation that predisposes you to sleeplessness and memory lapses. Science fiction, or soon reality? The latter, at least if we are to believe Anders Sandberg, who has a Ph.D. in computational neuroscience and is currently a philosophy researcher at the Future of Humanity Institute at Oxford University in England. He is looking into how today’s rapid technological development influences the way we view our illnesses. “One result of developments is that we have ill- text: Tobias Hammar photo: Anthony Oliver nesses that are much more individualized than before. You no longer have a ‘cold’ but carry the ‘CV-A2’ virus. Maybe it doesn’t make you any healthier, but your diagnosis is more specific,” he says, and adds: “It’s the same thing when you are admitted to hospital. In 20 or 30 years hospital scans will be routine, thanks to ever cheaper MRIs. The advantage of this is that we will gain a good picture of each patient. The disadvantage will be the discovery of a horrendous number of trifling ailments. Even though we will actually be healthier, we will feel significantly worse because all of us will have a diagnosis of something.” n n n our rapidly changing lifestyles mean that the concept of illness will be rethought from top to bottom But improved diagnostics are only one result of tomorrow’s increasingly advanced technology. Another is that the boundary between “ill” and “well” will shift. “Traditional healthcare is aimed at curing, relieving or preventing illness. But in the future we will have new opportunities to ‘improve ourselves’ in various ways with the aid of technology.” This opens the door to new ethical dilemmas, Sandberg asserts. Because even if we continue to prioritize healthcare for whooping cough and cancer for example, it will be significantly more difficult to decide whether or not it is “good” to use medicinal science to develop physically stronger bodies or biological super memories. In the long run our rapidly changing lifestyles 11 “Most priorities will still be pretty simple. It’s never going to be particularly difficult to choose between the common cold and severe liver damage, for example. The problem is that people have ever better knowledge of their conditions thanks to the internet. In some cases they actually know more than their doctors, and this also means they expect more care. Doctors will have to get better at saying no.” So in the years ahead you can count on a very noisy battle over where the border between illness and normality is to be drawn. The debate is under way in many countries right now. The UK, where Anders Sandberg works, is well ahead in the discussion about human enhancement medicine. The USA is hesitant for religious reasons, while continental Europeans are debating the judicial aspects. In the Nordic region we have taken something of an in-between position. n n n mean that the entire concept of illness will be rethought from top to bottom. If forgetfulness, sleeplessness or being burdened with various dependencies were considered perfectly normal yesterday, these traits will in future be seen as something abnormal and unhealthy – and therefore suitable subjects for medical treatment. “This progress is ongoing. Caries, alcoholism and obesity are examples of conditions that were regarded as normal in the past, but which over time have come to be looked on as diseases. And in Japan, body odour is considered to be ‘unhealthy’,” says Anders Sandberg, who adds: “Many improvements will be directed at our lifestyles rather than our jobs. Perhaps it will interest us more to manipulate our ability to sail boats or climb mountains, for example. And with our new power to switch various genes on and off, we might in time also be able to medicate away the traumatic effects of a troubled childhood.” n n n Essentially this value shift can be reduced to one single meme: you the individual will bear increasing responsibility for not being in top form, regardless of whether your flaws are physical, emotional or mental. But then how will this new approach to disease influence future ethical priorities? Ill or normal? It all depends when. Caries A condition we have had throughout the ages, but now declared a disease. Alcoholism Previously we only had moral objections, these days we have begun to see it as a mental illness beyond the alcoholic’s own responsibility. “staying alert” In the past we thought forgetfulness and tiredness to be natural in the elderly. Today we shoulder ever more responsibility for “staying alert”. Ginseng tablets, sudoku and other forms of stimuli cause us to expect permanent high performance. The big question of course is all about … money. “The fundamental rule is that we will happily pay for someone else’s healthcare when it provides average health, but no more. The state will presumably take care of the ‘basics’ – at least in the Nordic countries – while the individual will have to contribute privately toward anything he wants over and above average health. In other words, cosmetic surgery, memory enhancement, brain doping and gene therapy will continue to be private issues.” But it is clear that healthcare will be increasingly more expensive. Anders Sandberg talks of future healthcare as being an “à la carte” menu, where the patient will to an ever greater extent choose the health status he or she would like. Doctors will form part of an individual’s personal “health team” alongside the dietician, health promotion consultant, masseur and many others. “In terms of social values, it is clear that patients will become more like healthcare customers. They are beginning to place demands on their doctors, they travel to spas and they try out alternative treatments. This is something entirely new compared to just a decade or so ago. It will undoubtedly lead to those with more money being able to buy better health in the long term.” But we might well ask: Is this fair? “That’s always open to discussion. But it is obvious that no matter how we solve the financing, those with more money will always have better healthcare than the majority. And it is not only about money, but has also to do with the fact that people with a higher socio-economic status are usually better at making demands. They are just much better bellyachers than the rest of us,” says Anders Sandberg. n Anders Sandberg, 36 years old, from Solna, Sweden, is a researcher at The Future of Humanity Institute at Oxford University. He has a doctorate in computational neuroscience from Stockholm University and is a fellow founder of the Swedish think tank Eudoxa. chapter 2 how we’ll get help Photo: Alcor Life Extension Foundation 12 An extraordinary example of the hope surrounding future research is choosing to freeze one’s dead relatives so that they can be cured in the future. Here a surgeon is seen preparing his “patient” by injecting a special fluid into the circulatory system. The fluid protects tissue against freezing injury. Location: Alcor Life Extension Foundation, Arizona, USA. 13 Advances in research over the years have made the impossible possible, and the vain dream of eternal life no longer seems quite so unattainable. New discoveries continually contribute to new, advanced – and costly – treatments and medicines. We bring a status report from the sharp end of Nordic research. chapter 2 14 how we’ll get help at the sharp end Five years have passed since the human genetic code was mapped in its entirety. For health researchers, the map shows the way toward new, effective, but often expensive medicines. BUT DISEASES are fighting back. text: Mathias Luther, Patricia Bruun R esearchers are tremendously excited. Genetic maps not only enable them to foresee illnesses, but also to understand and predict how medicines will work. They are able to create and dose drugs extremely accurately. “Whereas the shotgun principal used before brought down whole flocks of pigeons, today we are able to snipe the single grouse we’re hunting for,” says Research Professor Sirpa Jalkanen. She leads the Academy of Finland’s spearhead unit studying human defence mechanisms. New medications are made in a different way to the old synthetic types. “Biotechnical drugs are produced by cells from bacteria or mammals that are genetically modified especially for the purpose. The cells are able to produce substances that are much more complex than those we can synthesize chemically in the test tube,” says Jalkanen. The new drugs are more expensive than the old, often many times over. But doctors from every discipline argue that they are still worth the price to society, if they can make a bed-ridden or wheelchairbound patient able-bodied again. One example is Natalizumab, a promising medicine in the treatment of the severe neurological disease MS, which without treatment always leads to invalidity. MS often advances during periods of rapid deterioration, but Natalizumab halves the number of such episodes compared to the best earlier medicines. Its disadvantage is its high price, around 15,000 Euros per year. But in maintaining a patient’s ability to work, it can still be worthwhile for society. Natalizumab is a medication based on monoclonal antibodies, a growing family of advanced medicines. Describing the differences Genetic research has also meant that we can predict differences in human reactions to medicines. We call 15 of research it pharmacogenetics. The first findings came along in the 1950s when it was observed that Asians did not react to certain medications in the same way Europeans did. Today, now that the whole genetic map can be spread across the table, we see that 35 to 50 million Europeans lack the CYP2D6 gene – or have two – and that they therefore risk overdosing, serious side effects or no effects at all from around 15 per cent of medications in use. Doctors must choose other drugs for these people, or adapt doses individually. This is just one example among many. “Pharmacogenetics is an extremely important research avenue; it is the future,” says Mette Rosenkilde, Professor of Molecular Pharmacology at Copenhagen University, Denmark. And it is one of the areas Denmark is investing heavily in. She is involved in molecular biology research centred on cell membrane receptors. They are literally the keys to many illnesses and Rosenkilde expects “many exciting things” to happen in the next few years. Among others, the receptors that allow the HIV virus to gain entry to cells are under study. Cancer fighting back Much of what seemed impossible 20 years ago is now a reality. At the same time, researchers are forced to acknowledge one fact: for every question that finds an answer, new questions arise. Biology is dynamic. Viruses and cancer cells are often smarter than man. “It happens time after time,” says Professor Lea Sistonen, who researches cell stress in Åbo, Finland. Her colleague and husband Professor John Eriksson researches cell survival signals. A cancer cell being treated with a cytotoxin tasked with killing it, is able to “addict” itself, i.e. the cell mutates so that it instead becomes dependent on that particular toxin. “This is relatively recent knowledge,” informs 5 MAJOR future CHALLENGES How will we survive the great widespread diseases? Cancer, cardiovascular disease, neurological and mental illnesses all require continual research advances. 1 Sirpa Jalkanen leads the Academy of Finland’s spearhead unit studying our defence mechanisms. Mette Rosenkilde, Professor of Molecular Pharmacology at Copenhagen University, Denmark. Lea Sistonen, researcher in cell stress, Åbo, Finland. John Eriksson, researcher in cell survival signals, Åbo, Finland. How can we get our lifestyles to take a healthier direction? 2 How do we maintain the privacy of the individual in healthcare and research? 3 How can we attract doctors and medical students to continue research? 4 How do we replace animal testing without impairing results? 5 Sistonen. Researchers have been able to observe that cancer cells that are fought by stopping the supply of nutrients via the circulatory system learn to live even in these straitened circumstances. Lack of doctors in the lab Eriksson and Sistonen are doctors of philosophy and as cancer researchers they stand at the front line of SHORT MEDICAL GLOSSARY BIOTECHNICAL MEDICINES: Medicines made from genetically-modified cells that produce a specific molecule. CELL: CELL STRESS: We can compare a cell to a library. If we step into the cell’s nucleus we see shelves; they are chromosomes. There are books on the shelves; they are genes. A cell’s ability to survive depends on how well it can handle stress. Inside the cell’s nucleus there are also stress genes; they’ve been around for millions of years. PHARMACOGENETICS: An assessment of how one and the same drug has different effects on different people depending on their hereditary predispositions – genes. GENETIC RESEARCH: Mapping the role played by each single identified gene (there are about 20,000–25,000 in man) in how a person looks and functions. chapter 2 16 how we’ll get help medical research. In 2006 medical doctors formed less than one third of the doctoral candidates at medical faculties in Sweden, a proportion that is falling. The situation is similar in the other Nordic countries. Medical doctors are simply unwilling to do the research work that progress demands. The vacuum is filled today by researchers from other scientific disciplines. “During the past ten years we have seen that an increasingly large proportion of researchers at medical faculties come from disciplines other than medical studies. It is other healthcare personnel, chemists, biologists and engineers,” says Professor Steinar Hunskår, who heads the medical faculty research programme at the University of Bergen in Norway. “This has enriched medical research. They have brought with them other angles of approach and know ledge, especially technological, that is of great value.” But we also need the perspective and feeling for a patient’s problems and needs that can only be picked up in an operating theatre, the ward or a doctor’s surgery. “Unfortunately, research isn’t an attractive career opportunity for doctors,” continues Hunskår. “The pay structure is such that even the youngest doctor in a Norwegian hospital earns more than a wellqualified professor at a university.” Because it is difficult to attract doctors to research everywhere in the Nordic region, it has also become difficult to develop clinical research, which in one way or another takes place inside the health services. Often, but not always, it is clinical research that prevails, i.e. research that sets out to solve a given problem or create a certain product. Its counterpart is basic research that should properly only be carried out for the sake of scientific curiosity, regardless of what the knowledge will be used for. In the research strategies drawn up by among others the EU and the World Health Organization, a lot is said about putting knowledge to work to improve healthcare. The idea is that there is a lot of knowledge floating around out there that is not exploited. Many links in the chain The Finns Sistonen and Eriksson demand substantial investment in basic research. We have to pay for the entire knowledge chain, they say. They feel Finland is cheating on this. Sweden and GENETIC RESEARCH RAISES MANY ETHICAL QUESTIONS AND PHILOSOPHICAL MISGIVINGS Denmark make significant investments in basic research, and will also harvest useful applications by and by. The conventional wisdom that adult brain cells cannot renew themselves was shattered at the Karolinska Institute. It was able to show that there are neural stem cells that can divide and create new nerve cells. The discovery is of importance for treating among other things Parkinson’s disease. It was basic research in Denmark that led to modern antidepressant medications – happy pills such as Prozac and Cipramil. But Professor Olle Stendahl from Linköping, Sweden, who works with national evaluations of both Swedish and Finnish clinical research, even has examples of trail-blazing discoveries within clinical research. “The bacterium that causes stomach ulcers was discovered clinically by surgeons and this led to radically changed ulcer treatment – and thereby ended ulcer surgery, ironically enough. “Advances in anti-rheumatic medications, new medicines based on monoclonal antibodies, were made in collaboration between basic research and clinical research. They have revolutionized treatment. Some patients are literally able to take up their beds and walk,” says Stendahl. Ethical boundaries Olle Stendahl, Professor, Linköping University, Sweden. Steinar Hunskår, Professor Faculty of Medicine in Bergen, Norway. Treatments that cause new blood vessels to grow in the heart are being performed at the Karolinska Institute. It is known as regenerative medicine and the possibilities seem limitless. Recently a Finnish patient received a new upper jaw that had been grown beneath the patient’s skin, on the stomach. This was made possible thanks to stem cells, a technique that in turn results from genetic research. Genetic research and the use of stem cells that in certain cases have been extracted from human embryos, raises ethical questions and philosophical misgivings. The European Convention on Human Rights and Biomedicine forbids researchers from creating human embryos solely for the purpose of research. It is forbidden in many Catholic countries. Those Nordic countries that wish to continue with the research must reserve the right to do against the convention. SHORT MEDICAL GLOSSARY CLINICAL RESEARCH: Research that is not only conducted in the laboratory, but also partly around patients who are under treatment or who are taking part in medical tests. MOLECULAR PHARMACOLOGY: MONOCLONAL ANTIBODIES: The development of drugs based on an understanding of how molecules affect cells. Antibodies that have been made using cloning technology and that have shown themselves to be effective against certain kinds of rheumatism, cancer and leukaemia. NERVE CELL: NEURAL STEM CELL: A nerve cell, or neuron, is the type of cell in the nervous system responsible for receiving and passing on nerve impulses. Nerve cells are the nervous system’s building blocks. The central nervous system’s stem cells. Animal testing indicates that stem cell transplants may be able to be used to treat injuries to the central nervous system. 17 The EU has also stopped subsidizing research programmes that create new stem cell cultivations from human embryos, but cultivations begun before 2003 may continue. From an individual’s standpoint, having one’s hereditary dispositions mapped in detail is not entirely agreeable. In 2007, when the head of a gene laboratory in California paid his respects to James D Watson, the Nobel Prize winner and co-discoverer of the structure of DNA, he presented Watson with the latter’s genetic map, describing it as “the ultimate self-knowledge”. Watson was impressed by this effort and the great advances in technology. But the gene that predisposes its host to fall ill with Alzheimer’s disease, Watson did not want to see. n new nordic discoveries back problems no matter what friends make us healthier The significance of working life in back problems is overestimated, assert researchers at the University of Southern Denmark. They have found that people have roughly the same amount of back problems from their teens up to the age of 100. Researchers recommend that we discriminate between various types of back problem more carefully than before in order to observe their causes. Certain problems are clearly the result of work that e.g. involves a lot of lifting. In 2009, an international group of experts will study ways to reduce the problem. Health is not just molecules. In some cases it would also appear to be a question of language. National health researchers in Finland have discovered that Swedish-speaking Finns are healthier than the others. This also applies when comparing people belonging to the same social class, the same age group and living in the same town. The difference is attributed to something known as social capital. Swedish-speaking Finns seem to have a network of friends and relatives that functions better than the others’. Another difference may be that childhood conditions in Swedish-speaking Finnish homes in some way provide a better start in life. But how does this affect the body? Researcher Markku T. Hyyppä in Åbo, Finland, speculates in an article in the Finnish medical journal about the possibility of a secure social network enabling people to sleep better. hypochondriacs really are ill Even hypochondria may have a physical explanation. So suggests a survey of a small number of patients with a long history of hard-to-interpret symptoms and problems. There are minute differences in these patients’ brains that can be seen with a so-called PET imager, discovered a researcher in Åbo, Finland. He suspects that the patients’ nervous systems all-too-easily pass on pain impulses. PREDISPOSE: Increase the risk or chance of a given event happening. autopsies merely a memory brain discovery may help stroke patients Advanced medical imaging technology can be used to solve crimes. Linköping University in Sweden has developed a method using a combination of a CT scanner and an MRI camera to scan 3D images of deceased victims of crime. The images are examined in a computer and processed so that it is possible to clearly see internal injuries. The method is able to replace autopsies and is in many cases better. Brain cells that have been hit by a stroke have a mechanism for protecting themselves against what otherwise would be a threat of poisoning from calcium ions in cerebral fluid. The cells are able to rapidly shut off the calcium intake that normally forms part of the brain’s signaling system. This was discovered by researchers at the University of Oslo, in Norway. Calcium levels in brain cells should normally only be a fraction of the concentration in the fluid outside. But the cells need energy and oxygen in order to pump out excess calcium again. If blood circulation is disturbed the cells suffer a lack of energy and would be under threat of being swamped by calcium ions if they did not have a rapid shut-off valve. The discovery may be significant in the treatment of stokes and epilepsy. CELL MEMBRANE RECEPTORS : ANTI-RHEUMATIC MEDICATIONS: REGENERATIVE MEDICINE: Molecules that pass right through a cell’s outer wall in the manner of a door handle or key. They pass on different substances and signals to the cell. Combat rheumatic diseases, e.g. rheumatism. New medicines are available that interfere with the disease itself, not just the symptoms. They are promising, but extremely expensive. Replaces injured or diseased body parts with new, permanent parts that eliminate or reduce disease symptoms. STEM CELLS: Immature cells that are present in all multicellular organisms. They have two characteristics that distinguish them from other cell types: they are able to undergo a limitless number of cell divisions, and they can mature into several different cell types. chapter 2 18 how we’ll get help science fiction or reality? a good question 1 Cloning a human It is already technically possible to clone a human today, but we refrain from doing so for ethical reasons. But it cannot be ruled out that the first cloned human will be created within the next 30 years – there are in fact scientists who are willing to defy the general prohibition against human cloning. 3 Designer babies Are we on the way to a world of supermen with computer-linked brains, technically improved consciousness and robots in the bloodstream that make sure we are always well? We asked researchers which sciencefiction-like treatments are merely a myth, which ones we will experience in the future and what falls in between. text: Søren Rathje Because it is possible to genetically modify animals, it is in principal also possible to break into an unborn child’s DNA and alter its genes. We do not do this today because it is regarded as ethically indefensible. But there are already certain ways of having one’s own “designer baby”. It is not unheard of for childless couples to seek out especially goodlooking donors, and Nobel Prize winners have created their own sperm bank for those who want a clever baby … 2 Eternal life “The idea of an average life expectancy of 150 years, not to mention immortality, is pure science fiction,” says Sissel Rogne, Head of the Norwegian Biotechnology Commission. “For example, we are unable to predict future diseases; new ones will crop up, old ones will mutate.” On the other hand she has no doubt that the health gap will widen so that in future the well-off will live significantly longer than the less privileged. 19 4 A human machine “It is already possible today to substitute many body parts with high-tech replacements. And we will see much more of this in the future,” says author and ethics scholar Klavs Birkholm. However, one crucial issue is whether technology should solely be used to heal the sick, or also be used to make healthy people sharper and faster. This is where Birkholm sees ethical problems. “We will lose the mystique surrounding how far human skill and talent can take us. And the gap between rich and poor will also widen, because it will to a great extent be private individuals who would pay for this,” says Birkholm. 7 Medicine from DNA 5 Genetic testing So-called biomarkers give a hint about the diseases of tomorrow. They are already making a small appearance in healthcare, and they will have much greater significance in future. By using markers it is possible to get an indication of bodily health from quite small amounts of biological material. The market for tests and screening will on the whole grow markedly. “This will lead to a great deal of pressure being put on public healthcare, because everyone will be insisting on their rights,” says Sissel Rogne, head of the Norwegian Biotechnical Commission. Which is why she believes that this type of test will be much more common in the private sector, where people will pay for tests themselves. 8 Robot surgeons 6 Nanobots in the blood The development of nano robots is already in full swing all over the world, but we have only seen a tiny part of what will happen in this area. So thinks Ilpo Vattulainen, Professor of Biophysics. In the best case, these small robots that move through the blood, will not only be able to identify cancer cells, but also destroy them before they have time to spread. Vattulainen believes that this treatment will benefit many: “The lion’s share of all research comes from public resources, so I feel that this is something that will be for the good of all.” Operating theatre robots are in no uncertain terms already a reality. At the Karolinska Hospital in Stockholm, Sweden, two robots equipped with gripping claws are used chiefly in operations on cancer patients. But they do not operate entirely alone. The arms are controlled by the surgeon using two joysticks. Urologist Peter Wiklund expects that the future will see robots that can perform certain tasks autonomously. It is also theoretically possible today for the surgeon to be in a different place to the robot and patient. When the price of robots falls this may be a good way to economize on manpower resources, but right now it is still an expensive spearhead technology. Photo: Intuitive Surgical, Inc. It is highly likely that several global epidemics that would have disastrous consequences if allowed to spread unchecked will emerge in the future. In which case, DNA vaccine, made from DNA hosting a specific disease, will be an effective weapon. Today DNA vaccine is under development – tests are being carried out with HIV, malaria, tuberculosis, several types of cancer and a range of other diseases. 20 chapter 3 photo: anders hansson 21 who will pay? Carl-Axel is 65. He has been fat since he was 4. Neither he nor researchers know why. He has sought help for RLS (restless leg syndrome), sleep apnoea and carpal tunnel syndrome (his hands go to sleep because the nerves in his wrists are compressed), but he has never received timely, satisfactory help – “his condition depends entirely on his obesity”. He has had type 2 diabetes for a few years. The overweight will be one of the groups under threat when healthcare is forced to make tougher priorities. Carl-Axel Wildt does charity work in health and healthcare issues for the Swedish National Association for the Overweight. “It’s all too easy for the health service to blame obesity. It’s probably only a matter of time before cancer and type 2 diabetes. which are largely exercise and diet-related illnesses, end up in the same situation. Research and priorities are too focused on medications. Preventive healthcare should be the priority,” is his opinion. chapter 3 22 who’ will pay? the senior boom and the rise of new, more expensive medicines and treatments will stretch Nordic health service finances. the need to prioritize will be greater than ever. priorities in focus as the north ages text: Tobias Hammar 23 T hings look pretty grim. The words are Paul Lillrank’s, Professor of Production Economics at Helsinki University of Technology, Finland, when he was asked to sum up the condition of the health services in the four Nordic countries. “It’s not catastrophic, but close,” he adds, as if to emphasize that the patient is still with us, despite weak signs of life and poor future prospects. The reason for Lillrank’s gloom is easy to understand. The Nordic health services, established when populations were young, wallets full and optimism for the future great, are fast approaching a point where they must either be reformed from the bottom up, or suffer a long, agonizing disintegration. Changes in the demographic structure are placing health service finances under devastating pressure. Increasing life expectancies and an ever larger proportion of pensioners means that the number of people requiring care will triple in Nordic countries over the coming three decades, at the same time as financing opportunities via taxes become limited. The economic dependency ratio – the ratio between the numbers of gainfully employed in a country and those, who because of age, are outside the labour market – will increase by 20 per cent in 30 years as fewer and fewer must provide for more and more. Considering the traditionally low wages and strenuous working environment in healthcare it is easy to understand the economists’ dilemma: will there be people and money enough to handle the healthcare needs of the future? “From a public health perspective the Nordic countries are at the top in the Western world. We are healthier than most. But the macro-economic challenges are all the greater. Nordic healthcare budgets may well be increasing faster than in other countries, but nothing points to this being enough. Rather, the world trend is toward a falling tax burden,” says Lillrank. Dearer healthcare ahead The problem is made worse by more expensive drugs and forms of treatment – a trend that is also making present-day care more costly. According to a survey from the American pensioners’ organization AARP, prices for 140 of the most important specialized medications against cancer and other common age-related illnesses have risen more than three times faster than inflation over the past few years. The most expensive cost far more than $10,000 per patient per year. And as if this wasn’t enough, the political trend is also on a collision course with economic graphs. State healthcare commitments that guarantee patients the right to treatment within given maximum times is a phenomenon that has emerged in the Nordic countries during the last decade. Nordic healthcare budgets are increasing, but nothing points to this being enough The 9 most resourceconsuming disease groups 2 1 Cardiovascular diseases. Diseases of the liver, gall bladder and pancreas. 4 3 Skin diseases. Kidney and urinary diseases. 6 7 8 9 5 Birth etc. Neurological diseases. Gastrointestinal diseases. “It is yet another powerful cost driver. Guarantees put the entire system under pressure because the promises are made at the same time as many governments have pledged to balance their budgets,” says Kjeld Møller Pedersen, Professor of Health Economics at the University of Southern Denmark. He continues: “This certainly begs some interesting questions. How great is the political will to pay? Will we allow healthcare budgets to grow at the expense of other areas? I believe the debate around these issues will be pretty tough in the years ahead.” Public healthcare unable to cope One obvious change that many are counting on is a continued expansion of the private sector in step with a health service that is burdened more and more. Björn Lindgren, Professor of Health Economics at the University of Lund in Sweden, reckons that the whole Nordic welfare concept should be overhauled from top to bottom. “We will see an increased penetration by private health insurance, or alternatively, means-tested subscription systems. Either way, more and more healthcare will be private in future. The fundamental welfare state concept of publicly-financed and publicly-delivered healthcare quite simply cannot Pulmonary diseases. Bone and tissue diseases. Source: Ministry of Health, Denmark, 2006. Paul Lillrank, Professor of Production Economics at Helsinki University of Technology, Finland. Kjeld Møller Pedersen, Professor of Health Economics at the University of Southern Denmark. chapter 3 24 who will pay? cope with developments.” This trend is already well on its way in Denmark. Today, more than three million Danes have some form of private health insurance – a number that is steadily growing. The other Nordic countries are by tradition more sceptical to private elements in healthcare, even though private health insurance is making significant inroads in Sweden and Finland. Only Norway, with its exceptionally strong public finances seems to be bucking the trend. “Our financial position means that most Norwegians can count on continued public healthcare financing in the future. We also have higher incomes here, which makes the recruitment of above all doctors and specialists easier. But we have the same problems as our neighbours when it comes to care of the elderly and handicapped,” says Terje Hagen, Professor of Health Economics at the University of Oslo in Norway. However, not all experts are equally sure that private healthcare will be a must in the future. Inger Ekman, Professor at the Department of Health Care Sciences and Health at the Sahlgrenska Academy in Gothenburg, Sweden, believes that public healthcare can survive with a different modus operandi. She talks about “patient or person-centred healthcare”. “Today, healthcare is founded on big, resourceconsuming accident and emergency centres. But as the population ages, it will move increasingly toward chronic diseases. There will no longer be a need for the same type of health service directed toward acute illnesses. By changing perspective and adapting healthcare to the individual patient we will be able to save significant resources,” she says, and explains: “Something we always begin with when a patient is admitted is to try to find some form of disease process, a diagnosis. But there are plenty of conditions where we cannot find a pathology. It’s often a matter of inexplicable symptoms, and then the whole treatment becomes ineffective. By simply listening to the patient, we will be able to adapt care and support to each individual’s needs and resources which will make entire treatment procedures markedly cheaper.” Nevertheless, most indications show that we are moving toward a future where healthcare needs will exceed public resources. The question is what we do with the healthcare’s actual content. Will we need to change healthcare priorities? We need clearer insight into what our priorities will be, not least so that our citizens know what kind of insurance to buy Terje Hagen, Professor of Health Economics at the University of Oslo, Norway. Inger Ekman, Professor at the Department of Health Care Sciences and Health at the Sahlgrenska Academy in Gothenburg, Sweden. Clearer priorities Hitherto the healthcare systems of all the Nordic countries have succeeded in managing their priorities more or less behind closed doors. Choices were made either locally or at an overarching central level, and without being preceded by any noticeable discussion. In the future, however, politicians will no longer be able to sweep problems under the carpet. This issue must be taken up for debate. “It is a question of rights. We need clearer insight Björn Lindgren, Professor of Health Economics at the University of Lund, Sweden. into what our priorities will be, not least so that our citizens know what kind of insurance to buy,” says Lindgren. He and his colleagues agree that many of today’s illnesses will fall outside the public remit tomorrow. “Much of what is lifestyle dependent will disappear. There are medications that enhance one’s quality of life, but that are not directly justifiable by an illness,” he says. Whatever we do, the dilemma raises many issues. For example, should geriatric care be allowed to expand at the expense of other forms of care as our populations age? Should fertility and obesity treatments be handed over to private players? “The public sector will clearly still be responsible for basic healthcare in society, but otherwise things bode well for privatizations. At the same time I believe that demands placed on individual responsibility will increase. Many illnesses are lifestyle related. I won’t be surprised if tax incentives for taking care of personal health are introduced,” says Lindgren, and gives as examples the taxes and duties on tobacco and alcohol. In the same way, tax subsidies have long been used to encourage occupational health contributions from companies and employers. Leaner processes increase productivity But reprioritization will also affect the very infrastructure of healthcare. Aging brings with it a growing urbanization which will mean that the need for large, central general hospitals will rise in the future. “Smaller hospitals out in the country will be closed to make room for larger hospitals that bring together expertise and exploit the economies of scale,” says Møller Pedersen. Luxuries preventive care cosmetic medicine You will be expected to invest in your own health, and preventive care will presumably be managed by the individual. Similarly, you will be expected to seek out health information yourself. This will lead to a proliferation of services for healthier lifestyles, sponsored by employers and authorities. Cosmetic medicine will most likely be private, and will include conditions such as warts and squints. Even conditions such as Bogart-Bacall Syndrome, or dysphonia (a medical term for a type of hoarseness) will be “cosmetic” because they are not significant for basic health, so they will be private supplements. 25 there are medications that enhance one’s quality of life, but that are not directly justifiable by an illness But in the short term the most significant cost savings are expected to come from another direction – rationalizations. By tradition, all four Nordic countries have big, resource-consuming national health services. According to Lillrank there is a huge potential to make healthcare production processes more efficient. “Studies from all the Nordic countries show that as much as one third of all surgical operations are unnecessary or harmful. There is a great deal of slack in the system that can be hauled in without hurting anyone,” he says, and goes on: “If we apply the same kind of industrial flows and processes that the best companies in the private sector already use today, we would be able to improve healthcare productivity by up to 30 per cent. Add to that new innovations and the figure could be even higher. I think it is here we will see the fastest changes in the short term.” n – Future priorities chronic pain circumcision Chronic illnesses such as stomach pains, backache and neck pain that have unclear causes and that are largely psychosomatic will not be prioritized in the future, if the patient has not previously received treatment that is demonstrably effective. In order to avoid controversy and to save money, circumcision will be referred to private, cosmetic surgery. unnecessary tests unusual diseases ineffective treatments Diffuse symptoms are costly, and they will lead to a hunt for more effective tests at the same time as health services will be striving to minimize “unnecessary” tests. Examinations will become cheaper and simpler. Unusual diseases are becoming quite common, primarily through improved diagnostic methods and because we are able to distinguish between different causes of e.g. breast cancer. Some variants will be treated while others will receive less support. The focus will continue to be on those in most need and those who draw most benefit from a treatment. Healthcare will become less interested in stubbornly administering treatments that do not “take”, which will lead to an increased interest in finding efficient ways to measure what functions individually and universally. Source: Anders Sandberg, philosophy researcher at Oxford University chapter 3 26 who will pay? 24 Replies who pays for healthcare? nordic opinions on the future of healthcare USA, where some cannot afford healthcare.” Arne Refsum, Doctor and Fellow of the Norwegian Medical Association: “Private elements will become much more common. But this will apply above all to supplementary services such as cosmetic surgery. Hopefully, the private sector will inspire the public sector to do better.” Kristina Laksáfoss Søgaard, Project Manager at the Copenhagen Institute for Future Studies (IFF), Denmark: “The healthcare sector will be privatized to an increasing extent, because the elderly will in future have more money and will not content themselves with public healthcare standards. Another reason is that public healthcare finds it hard to do patient follow-up in many circumstances, due to recruiting problems and long hospital waiting lists.” Urban Janlert, Professor of Public Health Sciences at the Institute for Public Health and Clinical Medicine at Umeå University in Sweden: “The state or the county: publicly-financed healthcare is the model. In my opinion there should be a public safety net in a welfare society, otherwise there is a risk that things will be as they are in the more as customers who demand good, efficient service. One of many small changes could be to send SMS messages to patients to confirm that referrals have been received, for example.” Marianne Falk, Nurses Association Chairwoman, Finland: “Because resources are becoming increasingly scarce, more will be paid for by patients themselves in future. But at the same time, I believe that the major part of healthcare will continue to be public.” Torben Fridberg, Researcher in social politics and welfare at the Danish National Centre for Social Research in Copenhagen: “In Denmark healthcare will be financed privately to an increasing extent. The risk is that individuals will have to pay privately in order to get good quality. The nightmare scenario would be if healthcare were to be based entirely on private insurance, but I don’t believe it will ever go that far in the Nordic countries.” Ingrid Kössler, Chairwoman for the Swedish National Breast Cancer Association: “Major parts of healthcare will continue to be publicly financed, but because we now live so much longer we will need care much later in life. Healthcare must become more efficient to cope. We must look on patients of average. Cosmetic surgery, i.e. straightforward “enhancements” are things people will have to pay for themselves. A basic portion will be handled by national insurance, but more and more will be paid for privately. One way to counterbalance this debate would be to bring automation to healthcare – to make it more efficient.” Kalervo Väänänen, Professor of Cellular Biology in Åbo, and chairman of the committee that disburses Finnish Academy finances to medical research: “It is the responsibility of society to ensure that healthcare is available for the entire population. There are several ways to organize this in practice. We can envisage municipalities taking responsibility for basic healthcare (as is the case today in Finland) while specialized care could be transferred to the state (in Finland it is managed by municipal syndicates). This would provide economic equality among the municipalities. Both the state and municipalities could then purchase services from private companies.” Anders Sandberg, Philosophy Researcher at Oxford University in England: “More and more fields are seen as conditions we want to take care of. This foretells of healthcare becoming a pretty expensive affair. In purely general terms I don’t think people are willing to pay for the health of others if we are talking about their getting healthier than some sort Jakob Axel Nielsen, Minister of Health, Denmark: “Even in the future the public sector should pay when people fall ill and need treatment. In Danish healthcare, free and equal access applies, and this is how it should be in the years to come. But we must absolutely draw advantage from private hospitals, both by buying in extra capacity and allowing them to pressure public hospitals into providing the best care possible. Both patients and society as a whole benefit from healthy competition.” Inger Ekman, Head of Health Care Sciences and Health at the Sahlgrenska Academy in Gothenburg, Sweden: “We will continue to pay for healthcare via our taxes, but we will need to do it differently. The focus will be more on what resources we have, and how we can best use them. Today we tend to create a disease out of everything, which often leads to oversimplified solutions to fundamentally complex issues.” Paul Lillrank, Professor of Production Economics at Helsinki University of Technology, Finland: “Insurance copays will be raised. Citizens will have to pay more for normal basic healthcare; going to the doctor will be a bit like going to the hairdresser. The chronic ally ill will continue to have guaranteed public support and subsidies. In other words, you are on your own up to a certain level, beyond that there will still be some kind of ‘catastrophe insurance’. Overall, the flow of money will come to bypass the tax system more and more. We will have a larger element of private health insurance even though public healthcare will continue to ensure that no one ends up entirely outside the healthcare system.” Lisbeth Löpare-Johansson, Nurse and Vice-Chairwoman of The Swedish Association of Health Professionals: “Healthcare will continue to be financed through public funds, while various supplementary services will be increasingly in the hands of the private sector. We need a proper discussion about where the public boundary should be drawn. It is extremely important that we get our healthcare priorities right.” 27 tomorrow’s financing Trond Egil Hansen, Doctor, Nesttun, Norway: “Healthcare in Norway will see private financing increase. Those who can afford it will be able to pay for services themselves. There’s no way to prevent this. Problems will occur if the range of publicly-financed services dwindles because of private alternatives.” Anna Ortner, Clergywoman, Sollentuna Parish, Sweden: “We are headed toward a poorer Sweden where those who can afford to will take out private health insurance. It is a deplorable development when everyone does not have access to the same healthcare. We can only hope that profit-oriented companies take care of their employees’ health and that we try to hang on to welfare as best we can. The church will become an all-the-more important welfare player.” Mika Gissler, Professor at the Nordic School of Public Health in Sweden and Director of Development at Stakes in Finland: “The private sector will increase its business activities and cooperation between the public and private sectors will be increasingly common. Freedom of choice for patients will improve, especially in Finland. But public treatment and care will continue to be the most common form of organizing primary and specialist services in the Nordic countries.” ance. When we also add private insurance and copay fees from the patient, we end up with a very unwieldy whole. The result is that healthcare access is sometimes inadequate. The government has pledged to analyze these challenges in depth.” that we never need to prioritize between different health treatments.” transferred to the private sector and these will be financed by private health insurance. Today, almost three million Danes already have private health insurance, of whom 1.8 million have policies that provide access to surgery in private hospitals.” Steinar Hunskår, researcher at the Faculty of Medicine in Bergen, Norway: Terje Hagen, Professor of Health Economics at the University of Oslo, Norway: “In Norway we pay for healthcare through our taxes, via the public budget. Norway’s exceptionally favourable state finances mean that it is unlikely that this situation will change in the years ahead. The scenario in which financing is transferred to private health insurance or increased personal copay is of less immediate concern for Norway than it is for the other Nordic countries.” Björn Lindgren, Professor of Health Economics at the University of Lund, Sweden: “We will see a larger proportion of private elements when it comes to both healthcare production and financing in the future. The public model will remain as the basis, but fees and premiums will probably be significantly more risk related. In the same way as the subscriber system was introduced for dental care, where the patient binds himself to take good care of his teeth, we will see healthcare that places emphasis on the patient’s own responsibility for his health.” Päivi Sillanaukee MD, Director General, Ministry of Social Affairs and Health, Finland: “Who’s going to pay is not the most essential question. Healthcare services belong to the most fundamental of universal rights. The rules of the game must be fair, both when it comes to the collection of resources and the financing of care. Then everyone will receive services according to their needs, regardless of who pays. Today, Finnish healthcare is financed through taxes, statutory health insurance and income-related insur- Mette Rosenkilde, Professor of Molecular Pharmacology at Copenhagen University, Denmark: “The state must finance healthcare with the taxes our citizens have paid. Only in this way can we safeguard equal acess to good healthcare for all, regardless of income, age and state of health. This is the easy answer in a perfect world where there is no lack of doctors or nurses, and where there are such vast resources “We must invest in strong public healthcare to safeguard the most important healthcare services for us all. Healthcare should be free and financed through taxes. Increasing demands for treatment and care in the future will be a challenge for public finances. I think purchasing additional services, either directly or through insurance arrangements, will become more common.” Lisbeth Schultz, Nurse, Åland, Finland: “There will be more and more private healthcare alternatives. One hopes that they are able to pressure municipal healthcare into becoming better. But I believe the tax payer will continue to pay for the larger part of healthcare.” Kjeld Møller Pedersen, Professor of Health Economics at the University of Southern Denmark: “Healthcare will continue to be financed through taxes in Denmark even in the future. Some treatments will however be Ursula Tenglin, General Secretary, Swedish Cancer Society: “When it comes to cancer treatment I have difficulty in seeing anything but social financing. However, there will be greater diversity among those who carry out healthcare. It is important that there be mechanisms to ensure that everyone has the right to equal care.” Hannu Hanhijärvi, Programme Director at Sitra, the Finnish Innovation Fund: “The proportion of elderly is growing fast in comparison to the gainfully employed, and so we need new methods of approach to maintain today’s healthcare standards. Studies show that there is reason for optimism if we move away from current activity-based healthcare toward a result-oriented health service. Using the best methods and quality assessments there would seem to be scope for cost increases of around 20 per cent. In this case current fiscal financing appears to be sufficient. But a good private sector is necessary to keep up the necessary competition.” 28 6 key questions Nordic healthcare is faced with great future challenges. The number of people who will need care is growing. New medicines and treatments will come along that are better but more expensive than the old alternatives. Public sector resources will not be able to cover everything possible. Here are six key questions about the destiny of health and healthcare that must form part of a broad debate. 1 which diseases should society take responsibility for – and which ones not? 2 How shall we prioritize who should get care when more costly, better treatments come along? 3 what will the new epidemics be and how shall we stop them? 4 how shall we attract enough personnel for healthcare? 5 is it ok to pay our way to better care? 6 what must we do to live healthier? 29 If 2008 If is the leading Property and Casualty (P&C) insurance company in the Nordic area with around 3.6 million customers in the Nordic and Baltic countries and Russia. If has around 6,900 employees and offers the whole breadth of P&C insurance solutions and services, for everyone from private individuals to global industrial companies. 2008 was yet another successful year for If. De- spite the financial crisis the company exceeded its profitability goals for the fifth year running. Technical profit amounted to MSEK 5,273. The combined ratio was 91,8 per cent, decidedly better than the long-term goal of staying below 95 per cent. These successes are the result of systematic and long-term efforts in which strong customer focus, selective growth strategy and operational excellence form the main elements. If ’s business activities are pursued in the business areas Private, Commercial, Industrial, and Baltic & Russia. 30 Business Idea, Strategy and Financial Targets If’s vision is to be the leading property and casualty insurance company in the Nordic and Baltic Region with the most satisfied customers, leading edge insurance expertise and superior profitability. Business Idea If offers attractively priced insurance solutions that provide customers security and stability in their business operations, housing and daily life. Combined ratio 2008 91,8 % 2007 90,6 % 0 Strategic Goals 20 40 60 If’s goal is to establish better profitability and customer satisfaction in the long term compared to our competitors, coupled with high creditworthiness. Technical results Strategic Direction 2008 5 273 2007 5 226 Customer Value If will exceed customer expectations through superior insurance solutions, fast and accurate claims management and sympathetic behaviour. Focused Insurance Expertise If will purposefully strengthen the organization’s skills in developing, pricing and distributing insurance products, as well as in the areas of claims management and prevention. Nordic Business Platform If will create competitive advantage through economies of scale and know-how transfer through an integrated Nordic and Baltic platform. Investment Strategy with Balanced Risk If has adopted a low risk strategy in investments by maintaining a balance between insurance commitments and investment assets in terms of currency and duration. Surplus capital is invested to enhance total returns. 0 2 000 Easy to Reach and Relate to If is easy to make contact with, and its staff, products and services are easy to understand. Dedicated If takes initiative and cares about me. 2008 Forward Thinking If is always in the forefront with new ideas and products. If’s Annual Report 2008 % 6 000 8 000 MSEK 6 000 8 000 MSEK 5 337 2007 5 009 0 2 000 4 000 Average number group employees 2008 Denmark 464 Estonia 356 Finland 1,805 142 Lithuania 191 Norway 1,644 Russia 422 Sweden 1,875 Others 25 0 Reliable If keeps its promises and is there to help when needed. 100 Operating profit/loss Latvia Core values 4 000 80 500 Total number employees 6,924 1,000 1,500 2,000 31 Market and Competitors The Nordic region is the seventh largest P&C insurance market in Europe, with an estimated premium value of around SEK 200 billion. Europe has a total premium value of SEK 3,900 billion. In the total European P&C insurance market, If is the Nordic region’s largest and one of Europe’s 15 largest listed P&C insurance companies. The Nordic Region If is a pure P&C insurance company with an integrated Nordic business organization. In total, If’s market share is equivalent to around one fifth of the Nordic market. In Sweden, Norway and Finland If is one of the leading insurance companies with market shares of 20, 29 and 27 per cent respectively. In the Danish market, which is more fragmented, If is the fifth largest company with a market share of five per cent. The Nordic insurance market is relatively consolidated. The five largest companies have almost two thirds of the market and the four largest companies are established in more than one Nordic country. The largest companies’ market shares have increased since the middle of the 1990s. Competition in the Nordic insurance market has been intense over the past few years. For example, several players have displayed high levels of activity in strengthening their distribution capability via alliance partners and the internet. The market has also seen establishments from leading foreign companies primarily within the industrial sector, and banks that have expanded their product range with P&C insurance products, in some cases as actual insurers. The financial crisis and the subsequent economic slowdown has also affected the P&C insurance industry. Most important were the effects felt in every company on returns on equity, and also, indirectly, on the solvency situation as result of falling market values of investments. The P&C market as a whole, in the form of premiums earned, continues to be stable even though growth in certain product areas came to somewhat of a standstill during the second half of the year owing to lower economic activity. Concerning claims costs, inflationary pressure is expected to diminish slightly in the period ahead as capacity utilization falls. However, this decline will be from a relatively high level even during 2008. Turbulent developments on the financial markets will also increase demands on insurance companies to run healthy, efficient businesses. Market shares in Sweden Others 19% Länsförsäkringar 30% Folksam 14% Trygg-Hansa 17% Market shares in Norway Others 13% Sparebank 1 10% Gjensidige 30% TrygVesta 18% If 29% Market shares in Finland1) Others 16% Pohjola 27% Fennia 11% Tapiola 19% If 27% Market shares in Denmark1) TrygVesta 21% Others 31% If 5% The Baltic Region If is the largest player in the relatively consolidated Estonian P&C insurance market with a market share of 32 per cent. In the more fragmented Latvian and Lithuanian markets, If is the fourth and fifth largest player respectively. In 2008 If had a market share of 9 per cent in Latvia and 10 per cent in Lithuania. If 20% Alm. Brand 10% TopDanmark 19% Codan 14% Market shares Baltic Region Codan 22% Others 30% Gjensidige 7% BTA 13% If 14% Ergo 14% Applies to 2007. 1) If’s Annual Report 2008 32 If’s business areas If’s business activities are run from a Nordic perspective. Activities are divided into customer segments within the business areas Private, Commercial and Industrial. Baltic & Russia, with their special market circumstances, form a separate business area. Private Commercial If is the leading insurance company for private individuals in the Nordic region. Business Area Private has three million customers in Norway, Sweden, Finland and Denmark. The 2008 technical result was MSEK 2,807. Total combined ratio was 91,3 per cent. Business Area Commercial target group is companies with up to 500 employees. The business area is Nordic market leader and has around 330,000 companies as customers. The 2008 technical result was MSEK 1,562. Total combined ratio was 92,4 per cent. How was 2008 in your business area? “2008 went well! Profits were strong with a good combined ratio, lower cost ratio and increased sales. And we had successes in the market. For example, in Finland large investments such as our collaboration with the S Group, the introduction of a new advantage programme and our internet initiatives were great successes. In 2008 we passed the 100,000 mark in the number of child insurance policies sold in Norway, remarkable considering we have only provided child insurance for four years. In Sweden demand for the new StorHem policy, the country’s best household insurance, exceeded all expectations. And in Denmark, where If is otherwise a small player in the private market, we now insure every tenth new car thanks to a business model we imported from If in Sweden.” How was 2008 in your business area? “Once again we showed a really good profit. We have had a strong and anticipated improvement in profitability for a number of years now and this creates security for our customers, owners and staff. And that’s important, particularly now when the world is as turbulent as it is.” How will you be affected by the financial crisis? “If is a reliable partner even in stormy weather. We have been around for a hundred years and we will still be around in another hundred. And we will help our customers and our partners through this crisis, too. But obviously, If has not been left unaffected by the decline in national economies. A reduction in new car sales and fewer new buildings naturally limit our opportunities to be on the offensive, and it increases competition between insurance companies.” Line Hestvik, Business Area Private. What will you invest in during 2009? “Among other things we will launch our new website. The goal is to be the best insurance company on the internet when it comes to customer contact, service and sales. We will also automate and simplify claims handling so that our customers will have even faster service. And in Denmark we will exploit our position as challenger and really go on the offensive.” Premiums written, gross, by country How will you be affected by the financial crisis? “If stands on stable ground in this economic storm. But industry has been hurt and therefore so have our customers. Unfortunately we will probably see a number of business failures. And there are fewer new investments, so the insurance market will barely grow as a whole. But on the other hand it will not shrink either, at least not to any great extent. Companies will still have to insure existing buildings, vehicles, and staff etc. in the period ahead. Ivar Martinsen, “Our experience from previous recessions shows Business Area that companies are more careful with their assets, which Commercial. may lead to a reduction in the number of losses.” What will you invest in during 2009? “Many customers are facing major traumatic challenges now that the world is so financially insecure. If has the financial strength to be a reliable partner to those living through the full blast of the storm. This, together with our high-quality products and services means that we have every opportunity of strengthening our market position in the coming year. “We will develop a range of new customer benefits and be even more active in the market, despite these gloomy times. At the same time, we will make major IT investments with the aim of reinforcing our products and making things simple for our customers. 2009 will be a year for If to go on the offensive in the business market.” Premiums written, gross, by country Denmark 6% Denmark 10% Sweden 19% Finland 20% Finland 24% Sweden 38% Norway 47% Norway 36% If’s Annual Report 2008 33 Industrial Baltic & Russia Business Area Industrial is the biggest industrial insurer in the Nordic region and the fifth biggest purveyor of industrial insurance in Europe. Its customers are Nordic companies with sales of more than MSEK 500 and more than 500 employees. Business Area Industrial has around 1,300 customers. The technical result was MSEK 657. Total combined ratio was 93,4 per cent. Business Area Baltic & Russia comprises Estonia, Latvia, Lithuania and Russia. Customers number around 425,000, both private individuals and companies. The technical result was MSEK 183. Total combined ratio was 92,6 per cent. How was 2008 in your business area? “Profits were satisfactory, especially considering that If and the entire insurance industry was hit by a great number of large claims events last year. The first half of 2008 was the worst year for claims costs ever seen globally.” How was 2008 in your business area? “It was a dramatic year. The crisis hit the Baltic states hard. For example, we can see sales growth dropping off even though the volume increase is still above ten per cent. Profitability is excellent, but this is also partially due to the crisis. People are short of money and they drive less because petrol is expensive, so fewer losses result. In 2008 we acquired Region, a Russian insurance company, so now we are established in the private market there. It is an investment in the future with great potential. Even though Russia is now living through a difficult economic period, they will recover and we will be there. We got off to a good start; Region grew by more than 25 per cent in 2008.” How will you be affected by the financial crisis? “The financial crisis confirms If ’s position as the leading player in the major customer segment in our part of Europe. We have worked single-mindedly at being a professional partner to our customers, with transparent terms and conditions whose interpretation is agreed. This pays in tough times. Another effect of course is that those insurance companies that have, in contrast to If, been directly hurt by the crisis have had sigMorten Thorsrud, nificant problems in competing assertively. Business Area “I hope that the financial crisis will lead to Industrial. simpler insurance models. Today, many large customers make proposals that are so complex they cannot be easily looked over. We must achieve much more transparency. The risks with today’s arrangements are just too great.” How will you be affected by the financial Timo Vuorinen, crisis? Business Area Baltic “We clearly are affected. Especially in the Baltic & Russia. states which are in deep crisis and in my judgement it will be several years before the difficult period is over. In Russia the turnaround will probably be quicker.” What will you invest in during 2009? “In my judgement prices will rise. I say this with great humility because many large companies have been forced to the wall by the financial crisis. But many factors speak for price rises. Reinsurance has become more expensive since the many major claims last year. Risky competitors who fought on price for years are now threatened with ruin; their business model collapses as the cost of capital rises. The market will sober up and we will see a longer-term, more businesslike price structure.” What will you invest in during 2009? “We will make special efforts to strengthen our offers to existing customers in the Baltic states. We are especially important for them in these tough times. We will also launch new solutions for customers that are exposed economically, a group that unfortunately is growing fast in the Baltic states these days. And of course we are constantly reviewing our cost structure. “Our focus in Russia will chiefly be to integrate Region into If and exploit our mutual strengths in the market, for example by creating alliances with banks and car dealers.” Premiums written, gross, by country Premiums written, gross, by country Denmark 12% Finland 22% Norway 23% Sweden 42% Russia 12% Lithuania 20% Estonia 45% Latvia 23% If’s Annual Report 2008 34 Five-year Summary 1) Condensed Income Statement MSEK Premiums earned, net of reinsurance Claims incurred, net of reinsurance Operating expenses in insurance operations, net of reinsurance Allocated investment income transferred from the non-technical account Other technical income Other operating expenses Technical result 2008 2007 2006 2005 2004 36,635 35,128 34,837 34,426 32,764 -27,269 –25,795 –25,252 –25,028 –24,105 -6,372 –6,045 –6,063 –6,135 –6,233 2,242 1,894 1,602 1,537 1,816 249 272 210 164 406 -212 –228 –210 –179 –178 5,273 5,226 5,124 4,785 4,470 Investment income and other items Results before income tax 64 –217 1,702 2,708 849 5,337 5,009 6,826 7,493 5,319 Income taxes -1,451 –1,321 –1,955 –2,015 –1,290 Net profit/loss for the year 3,886 3,688 4,871 5,478 4,029 If’s Annual Report 2008 35 Balance sheet, December 31, current value MSEK 2008 2007 2006 2005 2004 Assets Intangible assets 1,335 1,138 1,228 1,324 1,359 Investment assets 98,036 94,307 89,796 92,283 80,815 Reinsurer’s share of technical provisions 4,686 4,573 4,711 5,192 6,129 Deferred tax assets 1,497 721 947 1,113 1,643 Debtors 9,750 9,069 8,087 7,901 7,230 Other assets, prepayments and accrued income 4,935 4,297 6,982 5,066 4,296 120,239 114,105 111,751 112,879 101,472 Total assets Shareholders’ equity, provisions and liabilities 17,140 18,504 19,304 24,363 20,822 Subordinated debt Shareholders’ equity 4,489 3,893 3,721 3,859 2,362 Deferred tax liability 4,011 3,640 3,603 3,087 1,921 Technical provisions 85,749 80,506 74,554 74,027 68,554 Creditors 6,109 4,655 7,705 4,645 5,013 Provisions, accruals and deferred income 2,471 2,907 2,864 2,898 2,800 120,239 114,105 111,751 112,879 101,472 Total shareholders’ equity, provisions and liabilities Solvency capital 24,143 25,316 25,681 30,196 23,462 Key data, property and casualty operations Claims ratio 74,4% 73,4% 72,5% 72,7% 73,6% Expense ratio 17,4% 17,2% 17,4% 17,8% 19,0% Combined ratio 91,8% 90,6% 89,9% 90,5% 92,6% Cost ratio 23,7% 23,7% 24,0% 24,3% 25,6% Key data, asset management Total return ratio2) -3,1% 2,6% 4,3% 5,8% 4,3% Other key data Regulatory capital Solvency margin Solvency ratio 1) 2) 21,890 23,426 25,400 25,985 6,199 6,094 5,868 5,938 21,482 6,368 65,7% 71,3% 73,6% 87,5% 69,8% S ince January 1, 2005 If applies International Financial Reporting Standards (IFRS), whereby all figures for 2004 have been recalculated in accordance with these principles and taking into account the stipulations contained in IFRS 1 First Timed Adoption of IFRS. Calculations have been made according to If’s internal principles for evaluation of asset management. Publisher: Försäkringsbolaget If. Production: Tidningskompaniet AB, Stockholm. Print: Trydells tryckeri, Laholm. Printed on eco-friendly paper. Cover picture: Getty Images. If’s Annual Report 2008 contact: Sweden: tel. +46 771 430 000, www.if.se Norway: tel. +47 980 024 00, www.if.no Denmark: tel. +45 77 01 21212, www.if.dk Finland: tel. +358 105 1510, www.if.fi
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