Injectable Liquids Unit Measures Injectable medications May be unstable in solution Packaged in powder form. Package or label directions must be followed Amount and type of diluent to use Strength of the prepared solution Proper storage after reconstitution Length of time the preparation can be safely used Package directions may list several preparation methods to yield different strengths of medication Select the strength closest to the ordered dose Consider the number of injections required for administration The ordered dose should be administered in one injection Med may come with its own liquid for mixing and if this is the case, that liquid must be used. If liquid not provided, label will advise if there are any restrictions regarding the liquid to use. Most Commonly the liquid used is either sterile normal saline or sterile bacteriostatic water Pharmacy Floor stock Powders designed for oral use may be able to be reconstituted with tap water. Click to edit Master text Second level Third level Fourth level Fifth level Main Components of a Label 1. How to store the medication. 2. NDC number identifies the product. 3. Name of the medication. Some labels styles will have both Brand (Trade) name and generic name. 4. Concentration of the medication in the vial. Total amount of diluent 5. Unit dose of medication 6. How much liquid is in the vial after proper reconstitution. 7. How the medication should be administered 8. Usual dose of the medication. 9. Batch from which medication was taken from. 10. The last date the medication can be safely used. 11. Name of pharmaceutical company who manufactured medication. Multi-dose vial mark on the container Date and time of preparation Strength of the resulting solution Expiration of potency Storage directions Initials Practice 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. How is the med stored? What is the NDC number? What is the name of the medication? Concentration of the medication in the vial? Total amount of diluent? Unit dose of medication? How much liquid is in the vial after proper reconstitution? How the medication should be administered? Usual dose of the medication? Batch from which medication was taken? The last date the medication can be safely used? Name of manufacturer? On the following drug label, identify the routes for administration for which this preparation can be used. After reconstitution with 2.5 mL diluent, the strength of the Kefzol solution is 330 mg/ mL. To administer a dose of 500 mg, how many mL would you give? Order: Prostaphlin 500 mg IM q6h Label reads: Give ________ mL Prostaphlin oxacillin sodium for injection For IM use add 11.5 mL Sterile Water for InjectionU.S.P. Each 1.5 mL of solution contains 250 mg oxacillin. Order: Ticar 500 mg IM stat and q8h Label reads: How many mL would be given? Ticar ticarcillin disodium For IV or IM use. Add 12 mL Sterile Water for Injection, U.S.P. or 1% Lidocaine HCl solution (without epinephrine). Each 2.5 mL of solution will then contain 1 g ticarcillin. The medication ordered is 22 units Humulin R and 36 units Humulin N. You have 30 unit, 50 unit, and 100 unit syringes available to you. Which syringe would be the best choice to use? The medication ordered is 32 units regular and 40 units NPH. What is the total number of units of the combined dosage? According to the label, this medication is to be used within 48 hours of being mixed. If the drug was mixed at 0800 on 6/10, at what time and date should it be discarded? Choose the letter that corresponds with the correct answer. 0800 on 6/11 0800 on 6/12 0700 on 6/12 0800 on 6/13 The directions for reconstitution of a 1 g vial of antibiotic state to add 10 mL sterile water for injection, which yields a final volume of 11 mL. What is the dosage strength? Round to the nearest whole number. _________mg/mL According to the label, the dosage strength of a medication is 62.5 mg/mL. If you have 2 mL of the medication, how many mg do you have? ___________mg After an antibiotic is reconstituted, it must be stored in a refrigerator and used within 96 hours. A vial is prepared 05/13 at 0800. When does it expire? 05/16 at 0800 05/14 at 2000 05/17 at 0800 An antibiotic has been reconstituted for IM injection with a dosage strength of 280 mg/mL. There is now 1.8 mL in the vial. You need to give 250 mg every 12 hours. How many complete doses are in the vial? Order: 1 gram of an antibiotic 30 minutes prior to surgery. Supply: 2 gram vial to be reconstituted with 5 mL of sterile water for injection for an approximate final volume of 6 mL. What is the dosage strength after reconstitution? Round to the nearest whole number. You are preparing an IV dose of an antibiotic. Which dose is the least concentrated? Which is the most concentrated? A) 1,000,000 units per mL B) 500,000 units per mL C) 250,000 units per mL The order is for 300,000 units of an antibiotic. According to the label, the dosage strength prepared by adding 8.2 mL of diluent is 500,000 units/mL. How many mL of diluted drug will be needed for this order? You are preparing a medication for IM injection. The dose ordered is 200 mg. The vial contains 500 mg. What is the best choice for reconstitution? A) Add 9.9 mL to get a final dosage strength of 50 mg/mL. B) Add 3.8 mL to get a final dosage strength of 125 mg/mL. 400,000 units of a medication is ordered. According to the label, if 18.2 mL of diluent is added, the resulting dosage strength will be 250,000 units/mL. How many mL of diluted med will you need for this order? The order is for 1800 mg. According to the label, if 3 mL of diluent is added, the resulting dosage strength will be 300 mg/mL. How many mL of diluted med will you need for this order? The daily dosage of a medication is equal to 10 mL. According to the label, there are 50 mL in the bottle. How many days will it take for the patient to take all the medication? The medication label on the vial containing 6 g of medication instructs you to add 56 mL of diluent to make a final concentration of one gram in every 10 mL. How many mL total will there be in the vial after the diluent is added? The medication label on the vial containing 5,000,000 units instructs you to add 8.2 mL of diluent to make a final concentration of 500,000 units/mL. How many mL total will there be in the vial after the diluent is added? The order is for 500 mg. According to the label, 4.8 mL of diluent should be added to make a final concentration of 100 mg/mL. How many mL of diluted drug are needed for this order? 300 mg of a medication is ordered. According to the label, 3 mL of diluent should be added to make a final concentration of 300 mg/mL. How many mL of diluted drug are needed for this order? The medication order is for 800,000 units. According to the label, 3.2 mL of diluent should be added to make a final concentration of 1,000,000 units/mL. How many mL of diluted drug are needed for this order? The order is for 250 mg 3 times per day. According to the label, the dosage strength is 250 mg/5 mL. How many mL will the patient take in one day 500,000 units of a medication is ordered. According to the label, this vial contains 5,000,000 units. How many doses will this vial cover? According to the label, the vial contains 500 mg. How many doses of 125 mg each will this vial cover? According to the label, a vial containing one gram of a medication should be reconstituted with 3 mL sterile water. The dosage strength will be 300 mg/mL. Calculate how many mL will be in the one-gram vial after reconstitution. According to the label for an oral suspension, to reconstitute the med, 67 mL sterile water should be added to the powder. The resulting solution will measure 75 mL due to the volume of the powdered drug. What quantity in mL of the 75 mL represents the volume of the drug? 1 g of an antibiotic is ordered. According to the instructions, 20 mL sterile water should be added to the 1 g vial to reconstitute the med. The resulting dosage strength is 50 mg/mL. How many mL will be needed for a 1 g dose? ___________mL The medication order is for 100 mg. According to the label, after reconstitution with 30 mL of diluent, the dosage strength of this med is 40 mg/mL. How many mL will be needed for this order? The medication order is for 1 g. According to the label, after reconstitution with 2 mL of diluent, the dosage strength of this med is 1 g/2.6 mL. How many mL will be needed for this order? The order is 0.5 g. According to the label, after reconstitution with 10 mL of diluent, the dosage strength of this med is 50 mg/mL. How many mL will be needed for this order? The order is for 500 mg. According to the label, after reconstitution with 4.8 mL of diluent, the dosage strength of this med is 100 mg/mL. How many mL will be needed for this order? The amount ordered is 120 mg. According to the label, after reconstitution with 30 mL of diluent, the dosage strength of this med is 40 mg/mL. How many mL will be needed for this order? According to the medication label, adding 25 mL of diluent produces a dosage strength of 1 g/5 mL. The other choice for reconstituting states that adding 56 mL of diluent produces a dosage strength of 1 g/10 mL. Which amount of diluent would you choose to use to make the med more concentrated? The medication ordered is Humulin® NPH 12 units. What information is missing from the order? Consider the medication Humulin N U-100. What is the dosage strength of this drug? Identify the action time of Humulin N. A) rapid B) intermediate C) long The medication ordered is Humulin 50/50 40 units. To how many units will a 50 unit insulin syringe be filled for this dosage? The medication ordered is 42 units Humulin 50/50. To how many units will a 50 unit syringe be filled for this dosage? The medication ordered is 12 units Humulin R. To how many units will a 30 unit insulin syringe be filled for this dosage? The medication ordered is 18 units Novolin R. You have 30 unit, 50 unit, and 100 unit syringes available to you. Which syringe would be the best choice to use? The medication ordered is 57 units Humulin 50/50. You have 30 unit, 50 unit, and 100 unit syringes available to you. Which syringe would be the best choice to use? The combined insulin dosage is 8 units regular and 10 units Humulin® N. Indicate how many units should be drawn up in the syringe first and then how many units total to draw into the syringe. The combined insulin dosage is 22 units regular and 25 units Humulin N. Indicate how many units should be drawn up in the syringe first and then how many units total to draw into the syringe.
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