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SCIENTIFIC WORKING GROUP ON
THROMBOCYTOPENIAS AND PLATELET FUNCTION DISORDERS
SWG FOCUS AND MISSION
The EHA SWG on Thrombocytopenias was established at the EHA Congress in Lyon 2003. The
group subsequently expanded its field of interest with the inclusion of platelet function disorders.
The purposes of the group are:
• To promote education and instruction in platelet disorders.
• To develop guidelines for diagnosis and/or treatment of thrombocytopenias and platelet
function disorders.
• To promote clinical and laboratory studies on thrombocytopenias and platelet function
disorders. The studies are conducted under the auspices of the EHA-SWG, but are open to
collaboration with all interested researchers.
The SWG includes the following subcommittees:
• Adult ITP Francesco Rodeghiero (Italy)
• Childhood ITP ‐ Thomas Kühne (Switzerland)
• Platelets and hemostasis - Ingrid Pabinger (Austria)
• Inherited thrombocytopenias - Alessandro Pecci (Italy)
• Inherited and acquired platelet function disorders - Paolo Gresele (Italy)
• HIT - Andreas Greinacher (Germany)
• Biology of Megakaryocytes and thrombopoiesis - Nichola Cooper (United Kingdom)
• Thrombotic microangiopathies - Marie Scully (United Kingdom)
Chair Carlo L. Balduini, IRCCS Policlinico San Matteo Foundation and University of Pavia, Pavia,
Italy. ([email protected])
BOARD MEMBERS AND TERMS
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Nichola Cooper, Co-Chairman (UK) [email protected]
Ingrid Pabinger (Austria) [email protected]
Terry Gernsheimer (USA) [email protected]
Francesco Zaja (Italy) [email protected]
Mehdi Khellaf (France) [email protected]
Thomas Kuhne (Switzerland) [email protected]
The executive committee was responsible for coordinating the SWG from 2013 to 2015.
CONFLICTS OF INTEREST OF THE BOARD
Board members may participate in clinical trials sponsored by pharmaceutical. They may have also
spoken at meetings and given consultative advice for companies during the development of novel
therapies. The working party aims to maintain professional working relationships with the
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pharmaceutical companies, but also wants to act without any conflict in clinical trials, and in
establishing diagnostic and therapeutic guidelines.
MEMBERSHIP LIST: PEOPLE INVOLVED IN STUDIES PROMOTED BY THE SWG
Anna Savoia ([email protected]), Bauters Anne ([email protected]), Bayart Sophie
([email protected]), Benabdallah-Guedira S ([email protected]), Boehlen
Françoise ([email protected]), Borg Jeanne-Yvonne ([email protected]), Bury Loredana ([email protected]), Bussel James ([email protected]),
Cattaneo Marco ([email protected]), Cid Ana R. ([email protected]), Civaschi Elisa
([email protected]), Cuker Adam ([email protected]), De Candia Erica
([email protected]), de Maistre Emmanuel ([email protected]), Fabris
Fabrizio ([email protected]), Falcinelli Emanuela ([email protected]), Favier Remi
([email protected]), Ferster Alina ([email protected]), Fierro Tiziana
([email protected]), Fleury Dominique ([email protected]), Fontana Pierre
([email protected]), Glembotsky Ana C. ([email protected]), Heller Paula G
([email protected]), Hurtaud-Roux Marie-F ([email protected]), James
Chloé ([email protected]), Lanza Francois ([email protected]), LatgerCannard Véronique ([email protected]), Le Cam Duchez Véronique ([email protected]), Lecompte Thomas ([email protected]), Loffredo
Giuseppe ([email protected]), Magini Pamela ([email protected]), Marconi
Caterina ([email protected]), Martin-Coignard Dominique ([email protected]),
Mazzucconi Maria Gabriella ([email protected]), Melazzini Federica
([email protected]), Menard Fanny ([email protected]), Mercier Sandra
([email protected]), Mezzasoma Annamaria ([email protected]).
Minuz Pietro ([email protected]), Muñiz-Diaz Eduardo ([email protected]), Nichele Ilaria
([email protected]), Noris Patrizia ([email protected]), Notarangelo Lucia D.
([email protected]), Nurden Paquita ([email protected]), Pippucci Tommaso ([email protected]), Podda Gian Marco
([email protected]), Pouymayou Catherine ([email protected]), Pujol-Moix
Nuria ([email protected]), Randi Maria Luigia ([email protected]), Rigouzzo Agnes
([email protected]), Royer Bruno ([email protected]), Santoro Cristina
([email protected]), Saposnik Béatrice ([email protected]), Schlegel
Nicole ([email protected]), Sie Pierre ([email protected]), Siguret Virginie
([email protected]), Trichet Catherine ([email protected]), Trillot
Nathalie ([email protected])
ACTIVITIES
EHA-SWG Scientific Meeting
Given the success of the EHA-SWG Scientific Meeting on Focus on thrombocytopenia and
disorders of platelet function held in Lisbon 27 to 29 September 2013, this SWG, in collaboration
with the SWG on Bleeding and thrombosis, organized a new Scientific Meeting on Hemostasis
imbalance: Critical issues and Therapeutic approaches that was held in Barcelona from 18 to 20
September 2015. 100 participants from 24 countries attended the meeting, mostly European, but
also from Australia, Asia and North America. The evaluation by participant showed that the
meeting was greatly appreciated: 87% of the attendees would recommend the meeting to their
colleagues, and the same percentage indicated that their objectives were achieved. The meeting
was assessed by delegates with an average score of 8.3 (out of 10).
EHA Scientific Conference
This SWG, together with the SWG Bleeding and Thrombosis, had a major role in organizing the
EHA Scientific Conference ‘Bleeding disorders: increase your knowledge and improve patient
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care!’ to be held 14 to 17 September 2016 in Barcelona. This event has been endorsed by the
International Society on Thrombosis and Haemostasis.
SWG at the annual congress of EHA
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The annual meeting at the EHA congress has been held at the 20th Congress in Vienna.
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The proposal for the 2016 meeting to be held at the 21th Congress in Copenhagen has been
approved by the EHA.
Studies promoted by the SWG
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Pregnancy in inherited disorders of platelet function (coordinator Patrizia Noris). Launched at
the 18th Congress of EHA.12 centers involved, 65 pregnancies analyzed. Finished and
published (see below Civaschi et al).
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SPATA Study: Surgery in Platelet disorders And Therapeutic Approach (coordinator Paolo
Gresele). Launched at the 19th Congress of EHA. Finished, manuscript in preparation.
Preliminary results were presented at the 20th EHA Congress in Vienna (see below Gresele et
al).
Scientific publications mentioning the contribution of the SWG
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Elisa Civaschi, Catherine Klersy, Federica Melazzini, Nuria Pujol-Moix, Cristina Santoro,
Marco Cattaneo, Cécile Lavenu-Bombled, Paolo Gresele, Pietro Minuz, Paquita Nurden, Ana
R. Cid, Adam Cuker, Véronique Latger-Cannard, Remi Favier, Ilaria Nichele, Patrizia Noris on
behalf of the European Hematology Association - Scientific Working Group on
Thrombocytopenias and Platelet Function Disorders.
Analysis of 65 pregnancies in 34 women with 5 different forms of inherited platelet function
disorders.
Br J Haematol. 2015 Aug;170(4):559-63.
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Paolo Gresele, Patrizia Noris, Sara Orsini, Paula Heller, Cristina Santoro, Loredana Bury, R
Kadir, Diego Mezzano, Emanuela Falcinelli, Nora Butta, Ana Rosa Cid, Jose Rivera Pozo, Koji
Miyazaki, Fabrizio Fabris, Marc Fouassier, Claire Flaujac, Gul Nihal Ozdemir, Omamoto
Otomewo, Federica Melazzini, Remi Favier, Marco Cattaneo, J Bussel, E De Maistre, Y
Henskens, E De Candia, N Bernejo, Nicole Schlegel
Bleeding risk of surgery in patients with inherited platelet function disorders: outcome of 389
surgeries in 250 patients.
Oral presentation at the 20th EHA Congress in Vienna.
Guidelines and EHA Research Roadmap
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This SWG is involved in the development of the EHA guidelines on Mild bleeding disorders
(chair: F. Rodeghiero).
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Several members of the SWG were involved in preparing the section Platelet disorders (C.L.
Balduini editor) for the EHA Research Roadmap for Blood Disorders in Europe.