Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission EM Babbitt 4/4/2016 Aphasia Interventions: Partner Training & Treatment Intensity DISCLOSURES Iowa Conference on Communicative Disorders April 7, 2016 Edie Babbitt, M.Ed., CCC-SLP, Board Certified-ANCDS Rehabilitation Institute of Chicago Center for Aphasia Research and Treatment www.ric.org/aphasia Director, Leora R. Cherney, PhD, CCC-SLP, Board Certified-ANCDS Topics today: Life Participation Approach to Aphasia Neuroplasticity Principles Conversation for Adults with Aphasia Intensity Intensive using Computer Programs Comprehensive Aphasia Programs - Outcomes Ms. Babbitt received an honorarium for this presentation. Ms. Babbitt does not have any relevant nonfinancial relationships to disclose. RIC – Center for Aphasia Research & Treatment & Intensity Supported Ms. Babbitt receives a salary from the Rehabilitation Institute of Chicago. Develop, Implement, and Promote rehabilitation practices that: enhance communication skills of individuals living with aphasia facilitate engagement in life activities Engages community in special interest groups supported by SLPs and trained volunteers Conducts clinical studies to establish the efficacy and effectiveness of aphasia treatments Provides aphasia treatment in the Intensive Aphasia Program Educates staff on the techniques of Supported Conversation for Adults with aphasia Life Participation Approach to Aphasia Life Participation Approach to Aphasia Edoardo Matania (1847–1929) Theoretical Foundation ASHA http://www.asha.org/public/speech/disorders/LPAA/ Resources for Clinicians Aphasia Access http://www.aphasiaaccess.org/ 1 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission Social Practice Principles Equalizing social relations Creating authentic involvement Creating engaging experiences Establishing user control Byng & Duchan (2005) EM Babbitt 4/4/2016 World Health Organization: International Classification of Functioning Main Health Condition Environmental Factors Impairments - Body, Structure, Function Personal Factors Participation Restrictions Activity Limitations Principles of Neural Plasticity Living with Aphasia: Framework for Outcome Measurement (A-FROM) Wikimedia commons Kagan, A., Simmons-Mackie, N., Rowland, A., Huijbregts, M., Shumway, E., McEwen, S., Threats, T., & Sharp, S. (2008). Counting what counts: A framework for capturing real-life outcomes of aphasia intervention. Aphasiology, 22(3), 258280. Neural Plasticity is: The adaptive capacity of the central nervous system The mechanism by which the brain encodes experiences and learns new behaviors Living with Aphasia: Framework for Outcome Measurement (A-FROM) The mechanism by which the damaged brain “relearns” lost behavior in response to rehabilitation Kleim & Jones, 2008 Kagan, A., Simmons-Mackie, N., Rowland, A., Huijbregts, M., Shumway, E., McEwen, S., Threats, T., & Sharp, S. (2008). Counting what counts: A framework for capturing real-life outcomes of aphasia intervention. Aphasiology, 22(3), 258280. 2 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission Principles of ExperienceDependent Neural Plasticity Use it or lose it Use it and improve it Specificity Repetition matters Intensity matters EM Babbitt 4/4/2016 Principles of ExperienceDependent Neural Plasticity Failure to use specific functions can lead to functional degradation Training that uses specific function can lead to an enhancement The nature of the training experience dictates the nature of the plasticity Induction of plasticity requires sufficient repetition Induction of plasticity requires sufficient training intensity Time matters Salience matters Age matters Transference Interference Kleim & Jones, 2008 Different forms of plasticity occur at different times during training The training experience must be sufficiently salient to induce plasticity Training induced plasticity occurs more readily in younger brains Plasticity in response to one training experience can enhance the acquisition of similar behaviors Plasticity in response to one experience can interfere with the acquisition of other behaviors Kleim & Jones, 2008 Intensity of Aphasia Treatment Robey (1998) Meta-analysis of aphasia Tx: larger effect sizes with treatment 2 hrs per week or greater Bhogal et al. (2003) 5 studies with positive treatment effect 5 studies with negative treatment effect 8.8 hrs/wk for 11.2 wks 2 hrs/wk for 22.9 wks Cherney, Patterson, Raymer et al. (2008) 6 studies with 68 participants Regardless of treatment type, more treatment over a restricted time appears better Cherney, Patterson, Raymer (2011) 5 additional studies Equivocal results Cumulative Intervention Intensity • Dose Form - task in which teaching episode occurs 100 60 3 12 wks • Dose – # of therapeutic client acts per session • Session Duration – in minutes • Session Frequency – times per week • Total Intervention Duration (weeks/month) • Cumulative Intervention Intensity • 100 trials X 3x a week X 12 weeks = • 3600 productions of target skill Warren, Fey, Yoder 2007 Therapeutic Intensity Ratio • Intensiveness (massed vs distributed) 3 • Total # hours Tx per week 40 • Maximum # hrs Tx per week • Treatment Intensity Ratio • 3 ÷ 40 = 7.5% Patient characteristics Paradoxical Results Components of Treatment Wikimedia commons Supported Conversation Techniques for Persons with Aphasia Desired outcomes vs Workplace limitations Babbitt, Worrall, Cherney (2015) Baker (2012) 3 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission EM Babbitt 4/4/2016 ORLA®: Oral Reading for Language in Aphasia Living with Aphasia: Framework for Outcome Measurement (A-FROM) Supported by grants H133G010098, H133G060055 & H133G040269 from the National Institute on Disability and Rehabilitation Research, Department of Education PI: L.R. Cherney Kagan, A., Simmons-Mackie, N., Rowland, A., Huijbregts, M., Shumway, E., McEwen, S., Threats, T., & Sharp, S. (2008). Counting what counts: A framework for capturing real-life outcomes of aphasia intervention. Aphasiology, 22(3), 258280. Oral Reading for Language in Aphasia (ORLA®) Living with Aphasia: Framework for Outcome Measurement (A-FROM) Sentences and paragraphs repeatedly read aloud, first in unison with the clinician and then independently Theoretical Background Based on neuropsychological models of reading Improve reading comprehension by providing practice in grapheme-to-phoneme conversion As oral reading becomes more fluent and automatic, the reader can focus on comprehension (Cherney et al.,1986, 1995, 2010a,2010b) Kagan, A., Simmons-Mackie, N., Rowland, A., Huijbregts, M., Shumway, E., McEwen, S., Threats, T., & Sharp, S. (2008). Counting what counts: A framework for capturing real-life outcomes of aphasia intervention. Aphasiology, 22(3), 258280. ORLA® – Key Elements Oral reading is systematically applied in programmed format Focuses on connected discourse Permits modeling of more natural speech Allows practice on a variety of grammatical structures Graded based on stimuli length and reading level Wikimedia Commons 4 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission Stimulation approach Multimodal Responses Incorrect repetition of stimuli not forced or corrected responses followed by further stimulation i.e. correct responses are modeled Consistent with Principles of Learning Theory Active participation by the learner Repetitive practice in the overlearning of skills Use of meaningful materials that are graded in difficulty EM Babbitt 4/4/2016 ORLA® Procedure SLP sits opposite patient SLP reads stimulus aloud to patient 1. SLP reads stimulus aloud to patient, both point to each word 2. Both read aloud together, Pt points to each word (2x) SLP adjusts rate and volume ORLA® Procedure cont. 3. 4. 5. SLP states a word for patient to identify – 2x or one word from each line or sentence SLP points to word for patient to read out loud - 2x or one word from each line or sentence 1. Baseline Testing 2. Pre-Treatment Testing Treatment: 24 sessions of ORLA 3. Post-Treatment Testing 4. Maintenance Assessment Patient reads stimulus aloud SLP reads aloud with patient as needed 5 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission Conclusions C-ORLA® may be efficacious for people with chronic nonfluent aphasia Over a 6-week period, there was a trend for greater language improvement with increased intensity and amount of therapy After 24 treatment sessions, there was a trend towards greater improvement when sessions scheduled less intensively EM Babbitt 4/4/2016 Summary Trends Severe aphasia Greatest improvements in reading comprehension Moderate Greatest aphasia improvements in discourse production Mild-moderate Greatest aphasia improvements in written expression and discourse production Cherney 2010b Conclusions Cross-modal improvements consistent with previous findings when ORLA given by SLP or via computer with avatar Tx delivered over internet with SLP oversight may be an efficacious and cost effective option AphasiaScripts® Supported by Grant H133B031127 from the National Institute on Disability and Rehabilitation Research, Department of Education PI: L.R. Cherney Living with Aphasia: Framework for Outcome Measurement (A-FROM) Case Study - ROMJI Kagan, A., Simmons-Mackie, N., Rowland, A., Huijbregts, M., Shumway, E., McEwen, S., Threats, T., & Sharp, S. (2008). Counting what counts: A framework for capturing real-life outcomes of aphasia intervention. Aphasiology, 22(3), 258280. Introduction at Aphasia Conference Welcome lords, ladies, gentlemen, and honored guests. My name is Jim R I had a stroke eight years ago. And like many of you, I have aphasia. Living with aphasia can be a challenge. But stop, look around, we are in this together. I may have trouble finding the words I want to say. But I still have my sense of humor. That reminds me of a joke. Before you criticize someone, walk a mile in their shoes. That way, when you criticize them, You’re a mile away and you have their shoes! Thank you and enjoy the wonderful day ahead. 6 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission Background Scripts guide and facilitate identification of participants and actions involved in social situations Script knowledge includes: understanding remembering recalling the temporal organization of events in routine activities Script knowledge is not seriously compromised by aphasia for mild to moderate language deficits A sequence of sentences that a person typically speaks in routine communication situations Examples Ordering Making Talking pizza over the phone a doctor’s appointment with friends and family Cued Massed Practice Instance Theory of Automatization Automatic processing is fast, effortless, autonomous, and unavailable to conscious awareness Automaticity of skills achieved by retrieving memories of complete, context-bound, skilled performance Memories are formed with repeated exposures to a consistent task (ie – repetition and practice) (Logan, 1988) AphasiaScripts® Incorporates… Complete What is a Script? (Armus et al, 1989; Lojeck-Osiejuk, 1996) Script Training Rationale EM Babbitt 4/4/2016 meaningful segments vs single words Relevant discourse Communication partner Consistent practice Intensive practice Provides maximum support to facilitate accurate production; support is gradually decreased Intensive repetitive practice accomplishes automatization of script production Whole task, massed practice and drill can be accomplished by using repeated oral reading Cost effectiveness can be achieved with use of computers AphasiaScripts® Computer program providing practice in conversational script training Uses an animated agent with visible speech Allows repeated and consistent practice of an individualized conversational script 7 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission EM Babbitt 4/4/2016 Case Study: Jim R Case Study – Jim R 68 year old male 8 years post-stroke Moderate Broca’s aphasia WAB AQ 85.3 Scripts My name is Jim R I had a stroke eight years ago. Living with aphasia can be a challenge. Dialogue about a Mediterranean cruise Before you criticize someone, walk a mile in their shoes. Creating Scripts Considerations Identifying patient’s communication needs and interests for topics Type of script (dialogue or monologue) Number and length of conversational turns Grammatical Vocabulary complexity selection Conversation starters Dinner conversation with friends Ordering in a restaurant, pizza on the phone Talking to family (in person or on the phone) That reminds me of a joke. That way, when you criticize them, You’re a mile away and you have their shoes! Thank you and enjoy the wonderful day ahead. Types of Communication Situations Script Topics But stop, look around, we are in this together. I may have trouble finding the words I want to say. But I still have my sense of humor. Dialogue about family and interests And like many of you, I have aphasia. Monologue: Introduction to the Midwest Aphasia Conference Welcome lords, ladies, gentlemen, and honored guests. Visit exhibitions, museums, libraries Go to restaurants Go to the movies, theaters, concerts, plays Go shopping Play with or help children or grandchildren Visit friends or relatives Talk to sales people in stores Severe Apraxia of Speech Talk on the phone to friends and family Make appointments over the phone Order over the phone Tell stories and jokes Discuss finances with banker, accountant, lawyer Ask for directions Discuss your health with your doctor Wernicke’s Aphasia Siblings, Parents, Kids, Grandkids, Nieces/Nephews Giving a testimonial in church Telling jokes Stroke and Aphasia story Favorite vacation/travel Well known family stories from the past Starbucks orders 8 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission EM Babbitt 4/4/2016 Moderate Broca’s Mild Broca’s Aphasia Aphasia AphasiaScripts® Research Team Rehabilitation Institute of Chicago Leora R. Cherney, PhD, CCC-SLP, BC-NCD Edie Babbitt, MEd, CCC-SLP Rosalind Hurwitz, MA, CCC-SLP Jaime Lee, MA, CCC-SLP Rosalind Kaye, PhD Center for Spoken Language Research Ron Cole, PhD Sarel Van Vuuren, PhD Nattawut Ngampatipatpong, MS Consultant Audrey L. Holland, PhD. CCC-SLP, BC-NCD Living with Aphasia: Framework for Outcome Measurement (A-FROM) AphasiaScripts® Summary Why use scripts? Instance Theory of Automatization Massed Practice Contextually-based Individualized Material What is Intensive Comprehensive Aphasia Therapy? Definition of ICAP Combination of therapy approaches Individual Group Technology Family Education High Intensity Cohort of participants in a defined amount of time Targets all areas of ICF RIC’s Intensive Comprehensive Aphasia Program (ICAP) What is a day like? 1 1 hour CILT hour Reading/Writing session 1 hour computer session hour conversation group 2 hours of Individual Treatment 1 Kagan, A., Simmons-Mackie, N., Rowland, A., Huijbregts, M., Shumway, E., McEwen, S., Threats, T., & Sharp, S. (2008). Counting what counts: A framework for capturing real-life outcomes of aphasia intervention. Aphasiology, 22(3), 258280. 9 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission EM Babbitt 4/4/2016 Evidence-Based Treatments Sample Schedule ASHA – Practice Portal ANCDS: Academy of Neurologic Communication http://www.asha.org/practice-portal/ Disorders and Sciences – Practice Guidelines http://www.ancds.org/index.php/practice-guidelines- 9#Aphasia SpeechBITE – Speech Pathology Database for Best Interventions and Treatment Efficacy http://speechbite.com/ Principles of Constraint Induced Language Therapy (CILT) Forced verbal response required Compensatory strategies prohibited Intensive therapy schedule Shaping verbal responses Words/short Then phrases longer phrases/sentences Barrier games selected for each individual; responses predetermined Pictures CILT Treatment Examples Severe Apraxia of Speech: Moderate Broca’s Aphasia: Mild Broca’s Aphasia: Visual cueing and choral productions Interest-based Complex stimuli, cueing as needed language tasks Wernicke’s Aphasia: Auditory comprehension Pulvermuller et al, 2001 Why treat writing ? Consider cognitive processes involved in comprehension and production of spoken and written words. If one process is significantly impaired by aphasia, can we use alternate process to enhance communication? Orthographic representations may be better preserved or more amenable to treatment than phonological representations. Motor control for writing may be more preserved. (Beeson, 2003) Conversation Group Treatment Multimodal communication Supported communication Goals may be: Use of technology Initiate Expect participants with aphasia to initiate, interact with each other NOT didactic SLP is NOT the “leader” SLP is the “facilitator” Repair, ask for clarification Use multimodal strategies 10 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission Individual Session Treatments EM Babbitt 4/4/2016 Treatments by Modality Verbal Expression RIC’s Intensive Aphasia Program Outcome Social Perspective: Stakeholder Views Behavioral Perspective: Language & Participation Changes Semantic Feature Analysis Phonological Feature Analysis Response Elaboration Treatment Melodic Intonation Therapy Reading Comprehension Auditory Comprehension Verb Treatments TUF V-nest Kendall’s Phonological Approach CATE Apraxia of Speech Drills Gesture + Verbal Multiple Oral Rereading Phase Phase 1: Retrospective Data Analysis 2: Stakeholder Perspectives Clinical Persons Phase Staff with Aphasia & Family Members 3: Neuroplastic changes Biological Perspective: Neuroplastic Changes Theory behind Outcomes Measurement Why is it important to evaluate ICAPs? Increase in number of intensive comprehensive aphasia programs (ICAPs) in US and abroad Unique model of therapy delivery Funded by individuals Bottom line questions: Are ICAPs effective and cost effective? Will services be reimbursed by insurance in the future? Donabedian described factors that are important in health care quality assurance: Structure Process Outcomes Rose, et al in press 2013 11 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission Structure: Attributes of settings in which care occurs • Material Resources, Facilities, Equipment, Money • Human Resources, Personnel, Administration EM Babbitt 4/4/2016 Current ICAP outcomes Process: What is actually done in giving and receiving care Includes clinical treatment outcomes and research studies Babbitt, Worrall, & Cherney (2015) Winans-Mitrik, Hula, Dickey, Schumacher, Swoyer, & Doyle (2014) • Provider/Patient activities in delivering/receiving care • Content of Care, Treatment Planning • Delivery of Care (frequency/duration of visits) Outcomes: Effects of structure and care on the health status of patients and populations • Improving patient's knowledge, changing behavior • Changes in satisfaction with care and effects on health care utilization • Changes in measures of cognitive/physical function Currently, 8 published papers about outcomes from ICAPs Babbitt, Worrall, & Cherney (in press) Persad & Wozniak (2013) Hinckley & Craig (1998) Dignam, Rodriquez, & Copland (2015) Rodriquez, Worrall, Brown, Grohn, McKinnon, Pearson, et al (2013) Code, Torney, Gildea-Howardine, & Willmes (2010) Should we expect to see improvements in all areas for all participants? Is improvement based on factors such as severity, type of aphasia, time-post-onset? Phase 1 Possible Factors Influencing Outcomes Measurable Factors Program Characteristics (or Process) Number of tasks in session Number of hours per day/week Type of therapy administered Personal characteristics Severity, etiology, location of stroke, size of lesion Difficult Factors to Measure Individual motivation Family support Expectations for recovery Pre-stroke language & cognition networks Social Perspective: Stakeholder Views BDNF and ApoE ԑ4 Biological Perspective: Neuroplastic Changes Clinician interpersonal and therapeutic skills Phase 1: Retrospective Data Analysis Questions Do 1st time participants show improvements on the following types of outcome measures: Impairment measures? Participation measures? Patient reported? Care-giver reported? What variables impact recovery? Behavioral Perspective: Language & Participation Changes Does time post-onset impact the amount of improvements on pre-post measures? Does severity of aphasia impact the amount of improvement on pre-post measures? Participant inclusion 12 cohort sessions Total number of participants = 114 Sept 2008 to April 2014 83 first time participants included in data analysis 1 unable to complete pre & post testing due to severity of cognitivecommunicative deficits Does type of aphasia impact the amount of improvement on pre-post measures? 12 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission Impairment Measures Western Aphasia Battery R Aphasia Quotient Language Quotient Cortical Quotient Boston Naming Test Participation Measures: Patient and Family Reported Outcomes ASHA Quality of Communicative Life (ASHA QCL) EM Babbitt 4/4/2016 Phase 1: Regression Analysis Determine whether any variable or combination can predict improvement and develop a model Based on WAB R AQ change score Communication Confidence Rating Scale for Aphasia (CCRSA) Person with Aphasia Caregiver Social Perspective: Stakeholder Views University research setting Variety of # of years of experience, number of times participating in intensive programs Severity: Initial WAB R AQ Naming ability: Boston Naming Test Cognitive Measure: WAB R subtest Raven’s Progressive Matrixes Confidence: CCRSA Only AGE was significant for predicting who would achieve > = 5 Could NOT determine a model of variables that contribute to improvements Phase 2: Stakeholder Perspectives Phase 2a: Clinician Perspectives Phase 2b: Perspectives of Persons with Aphasia & Family Members Methods Graneheim & Lundman (2004) to guide analysis of interviews Read through interview multiple times Chunked into meaning units Condensed Veteran’s hospital All clinicians approached agreed to be interviewed Months post-onset (MPO) Results – Only AGE and MPO showed significant difference between the groups Seven clinicians from 3 locations Non-profit rehab hospital Type of aphasia: Non-fluent & Fluent Phenomenological Approach – describing one’s lived experience Biological Perspective: Neuroplastic Changes Phase 2a: Clinician Perspectives Age Behavioral Perspective: Language & Participation Changes Phase 2 Categorized into Responders (>= 5) and Non-Responders (< 5) Communicative Effectiveness Index (CETI) Factors/Variables Essence meaning units of thought Interviews re-read for support for main themes Reliability check 13 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission Intensive Therapy Model Learning & Support Intensive Comprehensive Aphasia Programs Rewards Hard work but rewards outweigh challenges Ability to go indepth Different view of aphasia therapy Seeing Progress Relationships EM Babbitt 4/4/2016 Learning more about diagnosis & treatment Learning evidence based treatments Factors in Job Satisfaction Support from other staff/mentors Between persons with aphasia Between family members Clinicans and PWA/Fam Members Challenges Time Patient Characteristics Potential for professional development Specialized skill training Can health care providers re-create specific functions of ICAP to provide services that enhance patient progress and clinician job satisfaction? Babbitt EM, Worrall LE, Cherney LR. (2013). Clinician perspectives of an intensive comprehensive aphasia program. Topics in Stroke Rehabilitation, 20(5), 398408. RELATIONSHIPS Interacting with clients, therapeutic relationships Support & collegiality from team work/mentors Helping people, making a difference Learning/expanding knowledge base ICAPs seem to support these factors Limited effectiveness due to client characteristics Lack of opportunity for professional development Scheduling/heavy workload ICAPs seem to overcome these factors Returning to typical clinical setting Discussion – Clinical Implications Variety in work Factors leading to Lack of Job Satisfaction "Sort of like you are in a life boat“ "like going away to college where you get a bond, all in the same boat” "Everybody has a story... listening to those stories you not only bond with them… great empathy for their situation." "never interacted with anybody" with aphasia Phase 2: Participants & Families Purposeful sampling from April and Oct 2014 sessions 12 Participants, 10 Family members 6 spouses 1 daughter 3 parents (Mom & Dad for 1 participant) 3 Females, 9 males Range of aphasia severity levels and different types 7 non-fluent 5 fluent/anomic ENVIRONMENT "You know it's like the people I like I like.” “We had a good laugh at a lot of those things” “These guys are funny, it’s everybody, that’s like ‘well what do you think?’” “Would have been nice to have a little more contact with the various families.” "It's more intimate. We have this family room where we connect which we don't have that with the other kinds of therapies my husband has access to" "Family room... that's really where you got all of the stories... Family education sessions "allowed for relationships and learning to happen" "He really liked going there, an office, similar to what he used to do for work. Get dressed up, go downtown. You go to work, you do your thing. That was really good and it made you feel like this was this was more what my normal life used to be." “Family room was too small” 14 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission INTENSITY EM Babbitt 4/4/2016 OUTCOMES "In-depth, challenging, hard" "Every day… very keeping keep keep keep (snapping fingers). “Fast paced” “It was fun but very grueling.” "Other speech therapy more broad, not specific" "Well it was different. That one was 1-2 and there was 10“ (comparing to previous therapy) "Was this was a higher level in terms of intensity and work? No doubt." "It was work to him and he needed work, this work" “Oh my God yes. Tired tired.” "Awesome, Grow, Challenge brain, excited, happening "But here more words. Oh my gosh. different.” “He speaks in more complete sentences. Before it was just a word or two " "It's accelerated… I might have made the same process but it might take a lot longer.“ “Speed at which I can think is slower than it used to be, getting better now” "Started walking all over without his cane… making a lot of physical progress." "More confident, fine on his own, talks to people in restaurants, went to local bar, talked to two strangers and the bartenders." Phase 3 RELATIONSHIPS INTENSITY Social Perspective: Stakeholder Views OUTCOMES Behavioral Perspective: Language & Participation Changes Biological Perspective: Neuroplastic Changes ENVIRONMENT Research Question Are there changes in specific language areas of the brain after participation in a 4 week intensive aphasia program? Present a case study of one participant who demonstrated significant improvement on a behavioral reading measure and increased BOLD activation on semantic judgment task Protocol • fMRI scan • Language • & Cognition testing Pre-testing ICAP • 4 weeks intensive aphasia therapy • fMRI scan • Language • & Cognition testing Post-testing 15 Copyright: Rehabilitation Institute of Chicago Do Not Copy Without Permission Boat Ship xptljm xqtlym EM Babbitt 4/4/2016 Future Directions Comparing to standard care Cost-benefit analysis Referrals? Please contact us at: Phone: (312) 238-6163 email: [email protected] or [email protected] RIC Center for Aphasia Research & Treatment 345 E Superior St. #1353 Chicago IL 60611 web: ric.org/aphasia 16
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