RB16 - The Jackson Laboratory

JAX® Mice, Clinical & Research Services (JMCRS)
Production Health Report
Area: RB16
MAXIMUM BARRIER
PATHOGEN & OPPORTUNIST FREE
HEALTH STATUS
BARRIER LEVEL
PATHOGEN FREE
HIGH BARRIER
STANDARD BARRIER
Please consult our website for descriptions of our health statuses and barrier levels.
PATHOGENS AND OTHER ORGANISMS‐ EXCLUDED FROM ALL BARRIERS (SHIPPING STOPPED) If one of these organisms is found in any JMCRS area, all shipments are suspended and customers are notified.*
Test Results: #positive/#tested
Organism
VIRUSES
Ectromelia virus
GDVII (Theiler's) virus
Hantaan virus
K virus
LDH elevating virus (LDEV)
Lymphocytic choriomeningitis (LCMV)
Mouse adenovirus (MAV)
Mouse cytomegalovirus (MCMV)
Mouse hepatitis virus (MHV)
Mouse minute virus (MMV)
Mouse norovirus (MNV)
Mouse parvovirus (MPV)
Mouse parvovirus (MPV)†
Mouse thymic virus (MTV)
Pneumonia virus of mice (PVM)
Polyoma virus
Reovirus 3 (REO 3)
Rotavirus (EDIM)
Sendai virus
BACTERIA & MYCOPLASMA
Bordetella spp.
CAR bacillus
Citrobacter rodentium
Clostridium piliforme
Corynebacterium bovis
Corynebacterium kutscheri
Helicobacter spp.
Mycoplasma pulmonis
Pasteurella spp.
Salmonella spp.
Streptobacillus moniliformis
Apr 24 '17 Mar 13 '17 Jan 30 '17
Previous 12 months
Sample Tested Test Method
Frequency
Jun 5 '17
Serum Serum Serum Serum Serum Serum Serum Serum Serum Serum Serum Serum Lymph node
Serum Serum Serum Serum Serum Serum MFI
MFI
MFI
ELISA
Enzyme
MFI
MFI
MFI
MFI
MFI
MFI
MFI
PCR
IFA
MFI
ELISA
MFI
MFI
MFI
6 weeks
6 weeks
6 weeks
annually
annually
6 weeks
6 weeks
6 weeks
6 weeks
6 weeks
6 weeks
6 weeks
6 weeks
quarterly
6 weeks
annually
6 weeks
6 weeks
6 weeks
0/13
0/13
0/18
0/13
‐
0/13
0/13
0/13
0/13
0/13
0/13
0/13
0/11
‐
0/13
0/13
0/13
0/13
0/13
0/16
0/16
0/16
‐
0/10
0/16
0/16
0/16
0/16
0/16
0/16
0/16
0/11
‐
0/16
‐
0/16
0/16
0/16
0/12
0/12
0/12
‐
‐
0/12
0/12
0/12
0/12
0/12
0/12
0/12
0/12
0/12
0/12
‐
0/12
0/12
0/12
0/15
0/15
0/18
‐
‐
0/15
0/15
0/15
0/15
0/15
0/15
0/15
0/11
0/15
0/15
‐
0/15
0/15
0/15
0/129
0/129
0/135
0/14
0/10
0/129
0/129
0/129
0/129
0/129
0/129
0/129
0/100
0/58
0/129
0/14
0/129
0/129
0/129
Oropharynx
Serum
Intestine or feces
Serum
Oropharynx/skin
Oropharynx
Intestine or feces
Serum
Oropharynx
Intestine or feces
Oropharynx
Culture
MFI
Culture
ELISA
Culture
Culture
PCR
MFI
Culture
Culture
Culture
6 weeks
6 weeks
6 weeks
quarterly
6 weeks
6 weeks
6 weeks
6 weeks
6 weeks
6 weeks
6 weeks
0/36
0/13
0/144
‐
0/47
0/36
0/06
0/13
0/36
0/144
0/36
0/27
0/16
0/131
‐
0/38
0/27
0/06
0/16
0/27
0/131
0/27
0/24
0/12
0/130
0/12
0/36
0/24
0/06
0/12
0/24
0/130
0/24
0/26
0/15
0/140
0/15
0/33
0/26
0/06
0/15
0/26
0/140
0/26
0/228
0/129
0/1146
0/59
0/302
0/228
0/54
0/129
0/228
0/1146
0/228
*Additional details regarding our health monitoring program and shipping policy.
†The indicated tests are only performed in rooms that house immunodeficient mice.
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Test Results: #positive/#tested
Organism
PARASITES & PROTOZOA
Encephalitozoon cuniculi
Ectoparasites (fleas, lice, mites)
Endoparasites (tapeworms,
pinworms, and other helminths)
Follicle mites
Opportunistic protozoa
(e.g., Giardia, Spironucleus)
Apr 24 '17 Mar 13 '17 Jan 30 '17
Previous 12 months
Sample Tested Test Method
Frequency
Jun 5 '17
Serum
Fur
MFI
Visual
6 weeks
6 weeks
0/13
0/06
0/16
0/06
0/12
0/06
0/15
0/06
0/129
0/54
Intestine or cecum
Visual
6 weeks
0/06
0/06
0/06
0/06
0/54
Subcutis
Visual
6 weeks
0/23
0/27
0/24
0/26
0/228
Intestine
Microscopy
6 weeks
0/06
0/06
0/06
0/06
0/54
OPPORTUNISTIC ORGANISMS MONITORED (SHIPPING NOT STOPPED)
All of these organisms are excluded from JMCRS maximum and high barriers, and most are excluded from standard barrier areas. When a confirmed finding of an excluded organism is made, an investigation is undertaken to identify and eliminate all infected mice from the barrier. Positive results‐ including results from investigations‐ are noted in this report, but shipping from the area is not suspended.*
Organism
Klebsiella pneumoniae Klebsiella spp. other than
K . pneumoniae
Nonpathogenic protozoa
(e.g., Trichomonads)
Pneumocystis murina †
Sample Tested Oropharynx,
intestine, or feces
Oropharynx,
intestine, or feces
Intestine
Frequency
Jun 5 '17
Culture
6 weeks
0/144
0/131
0/130
0/140
0/1146
Culture
6 weeks
0/144
0/131
0/130
0/140
0/1146
Microscopy
6 weeks
0/06
0/06
0/06
0/06
0/54
PCR
6 weeks
0/11
0/11
0/12
0/11
0/97
Culture
6 weeks
0/144
0/131
0/130
0/140
0/1146
Culture
Culture
Culture
6 weeks
6 weeks
6 weeks
0/144
0/36
0/36
0/131
0/27
0/27
0/130
0/24
0/24
0/140
0/26
0/26
0/1146
0/228
0/228
Gross Pathology
Test Method
Frequency
Jun 5 '17
Necropsy findings
Exam, histopath
6 weeks
0/23
Proteus mirabilis
Pseudomonas spp.
Staphylococcus aureus
Streptococcus spp.
Lung
Oropharynx,
intestine, or feces
Intestine or feces
Oropharynx
Oropharynx
Apr 24 '17 Mar 13 '17 Jan 30 '17
Previous 12 months
Test Method
Apr 24 '17 Mar 13 '17 Jan 30 '17
0/27
0/24
Previous 12 months
0/26
All tests were performed by The Jackson Laboratory
RB16
James R. Fahey, MS, PhD, DVM, DACVM
Chief of Diagnostic Services & Associate Director
Comparative Medicine & Quality
Page 2 of 2
The Jackson Laboratory
600 Main Street
Bar Harbor, ME 04609
1‐800‐422‐6423
0/228