CURRICULUM VITAE Name: Craig Michael Coopersmith, MD Work Address: 101 Woodruff Circle Suite WMB 5105 Atlanta, GA 30322 Phone (404) 727-4273 Fax (404) 727-3660 [email protected] Home Address: 2247 Dogwood Lane Atlanta, GA 30345 (314) 863-0350 Date of Birth: August 19, 1965 Place of Birth: New York, New York Family: Wife, Lois Spritzer Children, Zachary Alex Coopersmith (Born 12/99) Talia Naomi Coopersmith (Born 12/01) Education: 1987 B.A., Magna Cum Laude, University of Pennsylvania 1991 M.D., University of Pennsylvania School of Medicine Post-Graduate Training: 1991-1992 Intern, Department of Surgery, Barnes Hospital 1992-1993 Junior Assistant Resident, Department of Surgery, Barnes Hospital 1993-1996 Research Fellow, Washington University School of Medicine 1997 (1/1-7/1) Second Year Assistant Resident, Department of Surgery, Barnes-Jewish Hospital 1997-1998 Third Year Assistant Resident, Department of Surgery, Barnes-Jewish Hospital 1998- 1999 Chief Resident, Department of Surgery, Barnes-Jewish Hospital 1999-2000 Fellow, Surgical Critical Care, Washington University School of Medicine 2012 Woodruff Leadership Academy, Woodruff Health Sciences Center, Atlanta, GA Medical Boards & Licensure: 1992 Diplomate, National Board of Medical Examiners 1995 Missouri State Medical License, #MD106960 2009 Georgia State Medical License #063310 Professional Certification: 2000 Diplomate, American Board of Surgery 2001 Added qualifications in Surgical Critical Care, American Board of Surgery 2002 Fellow, The American College of Surgeons (FACS) 2003 Fellow, The American College of Critical Care Medicine (FCCM) 2009 Recertified, American Board of Surgery (General Surgery) 2010 Recertified, American Board of Surgery (Surgical Critical Care) Academic Appointments: 2000-2004 Assistant Professor of Surgery; Burn, Trauma, Surgical Critical Care Section, Division of General Surgery, Washington University School of Medicine 2000-2009 Attending Physician, Barnes-Jewish Hospital 2001-2004 Assistant Professor of Anesthesiology, Washington University School of Medicine 2001-2003 Associate Director, Surgical Critical Care Fellowship, Washington University School of Medicine 2001-2009 Associate Director, Anesthesiology Critical Care Medicine Fellowship, Washington University School of Medicine 2003-2009 Director, Surgical Critical Care Fellowship, Washington University School of Medicine 2003-2009 Director of General Surgery Resident Research, Washington University School of Medicine 2004-2009 Associate Professor of Surgery; Burn, Trauma, Surgical Critical Care Section, Division of General Surgery, Washington University School of Medicine 2004-2009 Associate Professor of Anesthesiology, Washington University School of Medicine 2009 (7/1-10/31) Professor of Surgery, Washington University School of Medicine 2006-2009 Co-Director, Surgical Intensive Care Unit, Barnes-Jewish Hospital 2007-2009 Division of Biology and Biomedical Sciences (Molecular Cell Biology Program), Washington University School of Medicine 2009-2010 Professor of Surgery (Visiting), Emory University School of Medicine 2010-present Professor of Surgery, Emory University School of Medicine 2009-present Director, Surgical Intensive Care Unit, Emory University Hospital 2009-present Associate Director, Emory Center for Critical Care Awards & Honors: 1987 Phi Beta Kappa 1996 Trainee Investigator Award for Excellence in Scientific Research, American Society for Clinical Investigation Biomedicine ‘96 Medical Research from Bench to Bedside. 1997 Samuel A. Wells, Jr. Resident Research Award, Washington University School of Medicine 1998 Alpha Omega Alpha 2000 Founder’s Grant for Training in Critical Care Research, Society of Critical Care Medicine 2000 Barnes-Jewish Hospital Team Quality Improvement Award (Blodstream Infection Team) 2002 Caring Spirit Award, Barnes-Jewish Hospital 2002 BJC HealthCare System Team Quality Improvement Award (Clinical Effectiveness of Phosphorus Repletion Guideline in the SICU) 2002-2007 Presidential Citation, Society of Critical Care Medicine 2003 Research Citation Award (given to top 5 posters) Society of Critical Care Medicine 2005 BJC HealthCare System Team Quality Improvement Award (Ventilator Associated Pneumonia Prevention Team) 2001, 2004, 2006, 2008 Teacher of the Year, Surgical and Burn/Trauma Intensive Care Unit, BarnesJewish Hospital 2008, 2009 St. Louis “Best Doctors”, St. Louis Magazine 2009 Outstanding Faculty Mentor Award, Washington University Postdoctoral Society 2009-2011 Best Doctors in America Professional Organizations: American Surgical Association American Medical Association American College of Surgeons Association for Academic Surgery Shock Society Society of Critical Care Medicine Society of University Surgeons Surgical Biology Club II Surgical Infection Society Peer Review: Editoral Boards/Consultants/Guest Editor Positions: Editor, Critical Connections (2012-present) Editorial Board, Journal of the American College of Surgeons (2011-present) Editorial Board, Journal of Surgical Research (2007-present) Editorial Board, Critical Care Medicine (2006-present) Editorial Board, Shock (2005-present) Editorial Consultant Physicians' Information and Education Resource American College of Physicians (2007-2011) Guest editor, Current Opinions in Critical Care, The Gastrointestinal System (2009) Peer review governmental/certifying boards United States: NIH, Center for Scientific Review, Surgery, Anesthesiology and Trauma Study Section (2011-present) NIH, Center for Scientific Review, Special Study Section ZRG 1 SBIB-E, chair (2010), ad hoc reviewer (2010, 2009, 2008, 2006x2, 2005) NIH, Center for Scientific Review, Special Study Section ZGM, PPBC-0, ad hoc reviewer (2010) American Institute of Biological Sciences on behalf of US Army Medical Research and Materiel Command (2009) American Board of Surgery, Associate Examiner for Certifying Examination (2006) International: Grant Review, Austrian Science Fund (2011) Grant Review, Medical Research Council (UK), (2010) College of Reviewers, Canada Research Chairs Program (2008) Grant review, National Health Laboratory Service Research Trust Grants (South Africa) (2007) Grant review, Netherlands Organisation for Health Research and Development (2006) Journal review Reviewer, American Journal of Infection Control Reviewer, American Journal of Pathology Reviewer, American Journal of Physiology Gastrointestinal and Liver Physiology Reviewer, American Journal of Physiology Regulatory, Integrative and Comparative Physiology Reviewer, American Journal of Respiratory and Critical Care Medicine Reviewer, Anesthesiology Reviewer, Annals of Surgery Reviewer, Archives of Surgery Reviewer, BMC Infectious Diseases Reviewer, BMC Microbiology Reviewer, Brain, Behavior and Immunity Reviewer, Chest Reviewer, Critical Care Reviewer, Critical Care Medicine Reviewer, Critical Care Research and Practice Reviewer, Digestive Diseases and Sciences Reviewer, Expert Opinion On Investigational Drugs Reviewer, Free Radical Biology and Medicine Reviewer, Journal of the American College of Surgeons Reviewer, Journal of the American Medical Association Reviewer, Journal of Gerontology: Biological Sciences Reviewer, Journal of Immunology Reviewer, Journal of Infectious Diseases Reviewer, Journal of Intensive Care Medicine Reviewer, Journal of Leukocyte Biology Reviewer, Journal of Pharmacology and Experimental Therapeutics Reviewer, Journal of Surgical Research Reviewer, Infection and Immunity Reviewer, Intensive Care Medicine Reviewer, International Journal of Radiation Biology Reviewer, Medicine Reviewer, Neurogastroenterology and Motility Reviewer, Shock Reviewer, Surgical Infections Reviewer, World Journal of Surgery Medical Center Committees: Washington University/Barnes-Jewish Hospital 2000-2009 Transfusion Committee 2001-2009 Graduate Medical Education Committee 2002-2009 SICU Outcomes Committee 2003-2009 Antibiotic Utilization Review Committee 2000-2002 SICU Bloodstream Infection Committee 2002-2005 SICU Insulin/Blood Glucose Control Committee 2003-2009 Director of General Surgery Resident Research, Washington University School of Medicine 2004-2005 SICU Ventilator Associated Pneumonia Prevention Committee 2005 Medication Reconciliation Committee (ad hoc member) 2006-2009 Institutional Review Board 2006-2009 Barnes-Jewish Hospital Critical Care Committee 2006-2008 Chair-elect Critical Care Committee 2008-2009 Chair, Critical Care Committee 2006 Data Safety Monitoring Board Siteman Cancer Center (for study HSC#02-0788) 2007 Dept. of Anesthesiology Ad Hoc Committee on Appointments and Promotions 2007-2009 KL2 (formerly K12) Clinical Scholars Selection Committee 2007 Institute of Clinical and Translational Sciences Novel Methodologies and Pilot Studies Program Review Committee 2008-2009 Disclosure Review Committee 2008 Clinical Research Training Center Post-doctoral Program Selection Committee Emory University and Emory Healthcare 2009-present Chair, Emory University Hospital Critical Care Committee 2011-present CLABSI team, Emory University Hospital 2011-present Medical Student Research Committee 2011-present Scientific Advisory Committee, Atlanta Clinical and Translational Science Institute 2012-present Interview committee for VP of Operations Emory University Hospital Professional Society Committee Memberships: Society of Critical Care Medicine 2002-2006 2004-2005 2002-2007 2004-2005 Program Committee Co-Chair Program Committee for 2005 Annual Congress (> 5000 attendees) Research Committee Chair Research Committee 2004-2011 Chair Task Force on Future of Research in SCCM 2002 Task force to respond to proposed Joint Commission on Hospital Accreditation ICU measures 2002 Reviewer for Norma J. Shoemaker Grant for Critical Care Nursing Research 2002-2004 Infectious Disease/Critical Care Medicine Ad Hoc Committee 2002-2005 Surgical Section Education Committee 2003-2005 A.S. Leardal Memorial Lecture Award Committee 2004-2005 2005-2008 2008 Co-Chair Laerdal Award Committee Publications Advisory Committee Chair, Publications Advisory Committee 2006-present Surgical Section Nominations Committee 2006-2009 American College of Critical Care Medicine Credentials Committee 2008-2009 Surgical Section Secretary/Treasurer 2009-2010 Surgical Section, Chair-Elect 2010-2011 Surgical Section, Chair 2010-present Strategic Planning Committee 2011 Vice chair, strategic planning committee 2011-present Strategic Education Committee 2008-present Council 2012-present Secretary Shock Society 2002-2005 2004-2005 Rules Committee Chair, Rules Committee 2005-2010, 2011-presentCouncil 2005-2008 2005-2008 Publications Committee Chair, Publications Committee 2007-2010 Scientific Program Committee 2009 Co-chair, Program Committee for 2009 Annual Congress 2009-2010 Chair, Program Committee for 2010 Annual Congress 2011-present Clinical Science Representative to Council Surgical Infection Society 2005-2007 Program Committee 2008-2011 Chair, Fellowship Committee Society of University Surgeons 2008-2011 Membership Committee American College of Surgeons 2006-2009 Trauma Committee (Missouri chapter) Grant Support: CURRENT (Peer Reviewed) Funding Agency: National Institutes of Health Period: 9/6/05-8/31/14 Grant Title: Mechanisms of Intestinal Apoptosis in Sepsis and Shock (R01 GM072808) Principal Investigator: Craig Coopersmith Total Direct Costs: $693,000 first funding cycle, $960,000 second funding cycle Funding Agency: National Institutes of Health Period: 7/1/11-6/30/16 Grant Title: Critical Care Training Grant (T32GM095442) Principal Investigator: Craig Coopersmith Total Direct Costs: $1,078,128 Funding Agency: Emory Alcohol and Lung Biology Center (which is funded by the NIH) Period: 1/1/12-12/31/12 Grant Title: Chronic Alcohol Ingestion and Sepsis (Pilot Project 1, P50AA013757) Total Direct Costs: $38,000 Funding Agency: James S. McDonnell Foundation Period: 12/1/07-11/30/12 Grant Title: Cognitive Complexity and Error in Critical Care (JSMF 220020152Collaborative Award) Principal Investigator: Timothy Buchman Co-investigator: Craig Coopersmith Total Direct Costs: $235,779 Trainees who applied and receive external funding for projects in Dr. Coopersmith’s lab are listed at bottom of CV. PAST (Peer reviewed) Funding Agency: National Institutes of Health Period: 7/1/02 – 2/28/11 Grant Title: Gut Epithelial Apoptosis in Shock and Sepsis (R01 GM66202) Principal Investigator: Craig Coopersmith Total Direct Costs: $651,000 first funding cycle, $840,000 second funding cycle Funding Agency: National Institutes of Health Period: 9/15/09-2/28/11 Grant Title: Collaborative Science Supplement (supplement to Gut Epithelial Apoptosis in Shock and Sepsis, R01 GM66202 to fund collaboration with Nicholas Davidson, MD) Principal Investigator: Craig Coopersmith Total Direct Costs: $72,721 Funding Agency: National Institutes of Health Period: 9/1/07-10/31/09 Grant Title: The Function of TREM-1 in Sepsis (R01 GM077279) Principal Investigator: Marco Colonna Co-investigator: Craig Coopersmith Total Direct Costs: $760,000 Funding Agency: Centers for Disease Control and Prevention Period: 1/29/01-10/31/09 Study: Washington University & BJC Epi-Center for Prevention of HealthcareAssociated Infection (1U01CI000333-01) Principal Investigator: Victoria Fraser Co-investigator: Craig Coopersmith Total funding: $631,330/year Funding Agency: National Institutes of Health Period: 5/28/09-8/31/09 Grant Title: Research Supplement to Promote Diversity in Health-Related Research (supplement to Gut Epithelial Apoptosis in Shock and Sepsis R01 GM66202 to fund fellowship of Alexandr Samocha) Principal Investigator: Craig Coopersmith Total Direct Costs: $5186 Funding Agency: National Institutes of Health Period: 6/1/08-8/31/08 Grant Title: Research Supplement to Promote Diversity in Health-Related Research (supplement to Mechanisms of Intestinal Apoptosis in Sepsis and Shock, R01 GM072808-01 to fund fellowship of Alexandr Samocha) Principal Investigator: Craig Coopersmith Total Direct Costs: $3723 Funding Agency: National Institutes of Health Period: 7/1/06-5/27/08 Grant Title: Research Supplement to Promote Diversity in Health-Related Research (supplement to Mechanisms of Intestinal Apoptosis in Sepsis and Shock, R01 GM072808-01 to fund post-doctoral fellowship of Jessica Clark, PhD) Principal Investigator: Craig Coopersmith Total Direct Costs: $106,517 Funding Agency: National Institutes of Health Period: 9/1/00 – 8/31/05 Grant Title: Intestinal Apoptosis in Shock and Injury (K08 GM00709-01) Principal Investigator: Craig Coopersmith Total Direct Costs: $514,307 Funding Agency: Society of Critical Care Medicine Period: 7/1/00 – 6/30/01 Grant Title: Intestinal Apoptosis in Shock and Injury Principal Investigator: Craig Coopersmith Total funding: $30,000 Funding Agency: Washington University Digestive Diseases Research Cores Center Period: 1/1/01 – 11/30/01 Grant Title: Intestinal Apoptosis in Ischemia/Reperfusion and Sepsis Principal Investigator: Craig Coopersmith Total funding: $3,000 Funding Agency: Centers for Disease Control and Prevention Period: 9/1/04-8/31/06 (R01CI000206-01) Study: Applied Research on Antimicrobial Resistance: Estimates of Economic Cost for Antimicrobial Resistant Human Pathogens of Public Health Importance Principal Investigator: Victoria Fraser Co-investigator: Craig Coopersmith Total funding: $466,600 Funding Agency: Agency for Healthcare Research and Quality Period: 9/30/01 - 9/29/04 Study: Surveillance, analysis, and interventions to improve patient safety (1/U18/HS11898-01) Principal Investigator: Victoria Fraser Co-investigator: Craig Coopersmith Total funding: $1,935,551 Publications: 1. Kim SH, Roth KA, Coopersmith CM, Gordon JI. Expression of wild-type and mutant simian virus 40 large tumor antigens in villus-associated enterocytes of transgenic mice. Proceedings of the National Academy of Sciences of the United States of America 91:6914-6918, 1994. 2. Chandrasekaran C, Coopersmith CM, Gordon JI. Use of normal and transgenic mice to examine the relationship between terminal differentiation of intestinal epithelial cells and accumulation of their cell cycle regulators. Journal of Biological Chemistry 271:28414-28421, 1996. 3. Coopersmith CM, Gordon JI. Gamma-ray induced apoptosis in transgenic mice with proliferative abnormalities in their intestinal epithelium: re-entry of villus enterocytes into the cell cycle does not affect their radioresistance but enhance the radiosensitivity of the crypt by inducing p53. Oncogene 15:131-141, 1997. 4. Coopersmith CM, Chandrasekaran C, McNevin MS, Gordon JI. Bi-transgenic mice reveal that Kras Val12 augments a p53-independent apoptosis when small intestinal villus enterocytes re-enter the cell cycle. Journal of Cell Biology 138:167-179, 1997. 5. Coopersmith CM, Lowell JA. Surgery of the small intestine. Current Opinions in Gastroenterology 15:146-150, 1999. 6. Lowell JA, Coopersmith CM, Shenoy S, Howard TK. Unusual presentations of nonmycotic hepatic artery pseudoaneurysms after liver transplantation. Liver Transplantation & Surgery 5:200-203, 1999. 7. Coopersmith CM, O’Donnell D, Gordon JI. Forced expression of Bcl-2 inhibits ischemia-reperfusion induced apoptosis in the intestinal epithelium of transgenic mice. American Journal of Physiology Gastrointestinal and Liver Physiology 276:G677-686, 1999. 8. Coopersmith CM, Brennan DC, Miller B, Wang C, Hmiel P, Shenoy S, Ramachandran V, Jendrisak MD, Ceriotti CS, Mohanakumar T, Lowell JA. Renal transplantation following previous solid organ transplantation: an 8-year single-center experience. Surgery 130:457-462, 2001. 9. Coopersmith CM, Chang KC, Swanson PE, Tinsley KW, Stromberg PE, Buchman TG, Karl IE, Hotchkiss RS. Overexpression of Bcl-2 in the intestinal epithelium increases survival in septic mice. Critical Care Medicine 30:195-201, 2002. 10. Coopersmith CM, Rebmann TL, Zack JE, Ward MR, Corcoran RM, Schallom ME, Sona CS, Buchman TG, Boyle WA, Polish LB, Fraser VJ. Effect of an education program on decreasing catheterrelated bloodstream infections in the surgical intensive care unit. Critical Care Medicine 30: 59-64, 2002. 11. Hotchkiss RS, Tinsley RW, Swanson PE, Grayson MH, Osborne DF, Wagner TH, Cobb JP, Coopersmith C, Karl IE. Depletion of dendritic cells but not macrophages in patients with sepsis. Journal of Immunology 168: 2493-2500, 2002. 12. Coopersmith CM, Stromberg PE, Dunne WM, Davis CG, Amiot DM, Buchman TG, Karl IE, Hotchkiss RS. Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumoniainduced sepsis. Journal of the American Medical Association 287:1716-1721, 2002. 13.Copersmith CM, Lowell JA, Hasam A, Howard TK. Hepatocellular carcinoma in a patient with focal nodular hyperplasia. HPB, 4: 135-138, 2002. 14. Zack JE, Garrison T, Trovillion E, Clinkscale D, Coopersmith CM, Fraser VJ, Kollef MH. Effect of an education program aimed at reducing the occurrence of ventilator-associated pneumonia. Critical Care Medicine, 30: 2407-2412, 2002. 15. Turnbull IR, Wizorek JJ, Osborne D, Hotchkiss RS, Coopersmith CM, Buchman TG. Effects of age on mortality and efficacy in cecal ligation and puncture. Shock, 19:310-313, 2003 -- lead (cover) manuscript. 16. Coopersmith CM, Amiot DM, Stromberg PE, Dunne WM, Davis CG, Osborne DF, Karl IE, Hotchkiss RS, Buchman TG. Antibiotics improve survival and alter the inflammatory profile in a murine model of sepsis from Pseudomonas aeruginosa pneumonia. Shock, 19:408-414, 2003. 17. Husain KD, Coopersmith CM. Role of intestinal epithelial apoptosis on survival. Current Opinions in Critical Care, 9:159-163, 2003. 18. Coopersmith CM, Stromberg PE, Davis CG, Dunne WM, Amiot DM, Karl IE, Hotchkiss RS, Buchman TG. Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest. Critical Care Medicine, 31:1630-1637, 2003 -- leading clinical investigation (cover). 19. Husain KD, Coopersmith CM. Intestinal apoptosis in shock and sepsis. Advances in Sepsis, 3: 2-7, 2003. 20. Husain KD, Stromberg PE, Javadi, P, Buchman TG, Karl IE, Hotchkiss RS, Coopersmith CM. Bcl-2 inhibits gut epithelial apoptosis induced by acute lung injury in mice but has no effect on survival. Shock, 20:437-443, 2003. 21. Ali S, Freeman BD, Coopersmith CM. Abdominal compartment syndrome in a patient resulting from pneumothorax. Intensive Care Medicine, 29:1614, 2003. 22. Taylor BE, Huey WY, Buchman TG, Boyle WA, Coopersmith CM. Treatment of hypophosphatemia using a protocol based on patient weight and serum phosphorus level in a surgical intensive care uint. Journal of the American College of Surgeons, 198:198-204, 2004. 23. Coopersmith CM, Zack JE, Ward MR, Schallom ME, Sona CS, Everett S, Huey W, Garrison T, McDonald J, Buchman TG, Boyle WA, Fraser VJ, Polish LB. The impact of bedside behavior on catheterrelated bacteremia in the intensive care unit.Archives of Surgery, 139:131-136, 2004 (cover). 24. Turnbull IR, Javadi P, Buchman TG, Hotchkiss RS, Karl IE, Coopersmith CM. Antibiotics improve survival in sepsis independent of injury severity but do not change mortality in mice with markedly elevated IL-6 levels Shock, 21:121-125, 2004 -- lead (cover). 25. Coopersmith, CM. Mitochondrial membrane dysfunction in endotoxemia: The difference between what's in and what's out, Critical Care Medicine, 32:607-609, 2004. 26. Javadi P, Buchman TG, Stromberg PE, Husain KD, Dunne WM, Woolsey CA, Turnbull IR, Hotchkiss RS, Karl IE, Coopersmith CM. Exogenous iron following cecal ligation and puncture increases mortality in mice and is associated with an increase in gut epithelial and splenic apoptosis, Critical Care Medicine, 32:1178-1185, 2004 (cover). 27. Wizorek J, Coopersmith CM, Laramie JM, Tong A, Stromberg PE, Hotchkiss RS, Buchman TG, Cobb JP. Sequence makes a difference: Paradoxical effects of heat shock in vivo, Shock, 22:229-233, 2004. 28. Turnbull IR, Buchman TG, Javadi P, Woolsey CA, Hotchkiss RS, Karl IE, Coopersmith CM. Age disproprotionately increases sepsis-induced apoptosis in the spleen and gut epithelium. Shock, 22:364368, 2004 – lead (cover) manuscript. 29. Coopersmith CM. Levosimendan and gut mucosal blood flow – not all inotropes are created equal. Critical Care Medicine, 33:246, 2005. 30. Hotchkiss RS, Osmon SB, Chang KC, Wagner TH, Roy S, Coopersmith CM, Karl IE. Accelerated lymphocyte death in sepsis occur by both the death receptor and mitochondrial mediated pathways. Journal of Immunology, 174: 5110-5118, 2005. 31. Carroll P, Saenz Robles MT, Markovics JM, Pope H, Coopersmith CM, Pipas J. Loss of p53 function is not essential for progression from intestinal hyperplasia to dysplasia. Journal of Virology, 79:74927502, 2005. 32. Javadi P, Buchman TG, Stromberg PE, Turnbull IR, Hotchkiss RS, Karl IE, Coopersmith CM. Iron dysregulation combined with aging prevent sepsis-induced apoptosis, Journal of Surgical Research, 128:37-44, 2005. 33. Hotchkiss RS, Coopersmith CM, Karl IE. Prevention of lymphocyte apoptosis – a potential therapy of sepsis? Clinical Infectious Diseases, 417:S465-469, 2005. 34. Husain KD, Stromberg PE, Woolsey CA, Turnbull IR, Dunne WM, Javadi P, Buchman TG, Karl IE, Hotchkiss RS, Coopersmith CM. Mechanisms of decreased intestinal epithelial proliferation and increased apoptosis in murine acute lung injury. Critical Care Medicine, 33:2350-2357, 2005. 35. Vyas D, Javadi P, DiPasco P, Buchman TG, Hotchkiss RS, Coopersmith CM. Early antibiotic administration but not antibody therapy directed against IL-6 improves survival in septic mice predicted to die based upon high IL-6 levels American Journal of Physiology Regulatory, Integrative and Comparative Physiology , 289:R1048-1053, 2005. 36. Freeman BD, Borecki IB, Coopersmith CM, Buchman, TG. Relationship between tracheostomy timing and duration of mechanical ventilation in critically ill patients, Critical Care Medicine, 33:2513-2520, 2005. 37. McConnell, KW, Coopersmith CM. Epithelial cells. Critical Care Medicine, 33:S520-522, 2005. 38. Taylor BE, Schallom ME, Sona CS, Buchman TG, Boyle WA, Mazuski JE, Schuerer DJ, Thomas JM, Kaiser C, Huey WY, Ward MR, Zack JE, Coopersmith CM. Efficacy and safety of an insulin infusion protocol in a surgical ICU. Journal of the American College of Surgeons, 202:1-9, 2006. 39. Woolsey CA, Coopersmith CM. Vasoactive drugs and the gut - is there anything new? Current Opinions in Critical Care, 12: 155-159, 2006. 40. Freeman BD, Kennedy CR, Coopersmith CM, Zehnbauer BA, Buchman TG. Attitudes regarding genetic research and testing held by individuals providing substituted judgment for critically ill patients. Critical Care Medicine 34: 986-994, 2006. 41. Hotchkiss RS, McConnell KW, Kelley K, Davis CG, Chang KC, Schwulst S, Dunne JC, Dietz GPH, Bahr M, McDunn JE, Karl IE, Coopersmith CM, Piwnica-Worms, D. Protection against sepsis-induced lymphocyte apoptosis via in vivo delivery of Tat fusion compounds. Journal of Immunology, 176: 54715479, 2006. 42. Schuerer DJ, Nast PA, Harris CB, Krauss MJ, Dunagan WC, Coopersmith CM, Ward M, Fraser V. Reporting of patient safety events in a surgical intensive care unit. Journal of the American College of Surgeons, 202: 881-887, 2006. 43. Robertson CM, Coopersmith CM. Systemic Inflammatory Response Syndrome. Microbes and Infection, 8: 1382-1389, 2006. 44. Warren DK, Jones RM, Coopersmith CM, Merz LR, Zack JE, Fraser VJ. The Epidemiology of Methicillin-resistant Staphylococcus aureus in a Surgical Intensive Care Unit. Infection Control and Hospital Epidemiology, 27: 1032-1040, 2006. 45. Freeman BD, Kennedy CR, Coopersmith CM, Zehnbauer BA, Buchman TG. Patients' and surrogates' perspective on research and testing in critical care. Critical Care Medicine 35: 328-329, 2007. 46. Schwulst SJ, Davis CG, Coopersmith CM, Hotchkiss RS. Adoptive transfer of dying cells causes bystander-induced apoptosis. Biochemical and Biophysical Research Communication, 353:780-785, 2007. 47. Warren DK, Guth RM, Coopersmith CM, Merz LR, Zack JE, Fraser VJ. The impact of an MRSA active surveillance program on contact precaution utilization in a surgical intensive care unit. Critical Care Medicine, 35:430-434, 2007. 48. McMullen KM, Zack J, Coopersmith CM, Kollef M, Dubberke E, Warren DK. The Use of Hypochlorite Solution to Lower Rates of Clostridium difficile – Associated Diarrhea. Infection Control and Hospital Epidemiology, 28:205-207, 2007. 49. McConnell KW, Muenzer JT, Chang KC, Davis CG, McDunn JE, Coopersmith CM, Hilliard CA, Hotchkiss RS, Grigsby PW, Hunt CR. Anti-apoptotic peptides protect against radiation induced cell death. Biochemical and Biophysical Research Communication, 355:501-507, 2007. 50. Harris CB, Krauss MJ, Nast PA, Kollef MH, Jacobsohn E, Avidan M, Coopersmith CM, Hill P, Dunagan WC, Fraser, VJ. Patient safety event reporting in critical care – an observational study of three intensive care units. Critical Care Medicine, 35:1068-1076, 2007. 51. Vyas D, Robertson CM, Stromberg PE, Martin J, Dunne WM, Houchen CW, Barrett TA, Ayala A, Perl M, Buchman TG, Coopersmith CM. Epithelial apoptosis in mechanistically distinct methods of injury in the murine small intestine. Histology and Histopathology, 22:623-630, 2007. 52. Robertson CM, Klingensmith ME, Coopersmith CM. Long-term outcomes of performing a postdoctoral research fellowship during general surgery residency, Annals of Surgery, 245:516-523, 2007. 53. Clark JA, Coopersmith CM. Just the right amount of JNK – how NFkB and downstream mediators prevent burn-induced intestinal injury, Critical Care Medicine, 35:1433-1434, 2007. 54. Byrnes MC, Coopersmith CM. Prevention of catheter-related bloodstream infection. Current Opinions in Critical Care, 13:411-415, 2007. 55. Jones JC, Rogers TJ, Brookmeyer P, Dunne WM, Storch GA, Coopersmith CM, Fraser VJ, Warren DJ. Mupirocin resistance in methicillin-resistant Staphylococcus aureus from a surgical intensive care unit, Clinical Infectious Diseases, 45:541-547, 2007. 56. Piel DA, Grubner PJ, Weinheimer C, Courtois MR, Robertson CM, Coopersmith CM, Deutschman CS, Levy RJ. Mitochondrial resusciation with exogenous cytochrome c in the septic heart, Critical Care Medicine, 35:2120-2127, 2007. 57. Schuerer DJE, Zack JE, Thomas J, Borecki IB,Sona CS, Schallom ME, Venker M, Nemeth JL, Ward M, Verjan L, Warren DK, Fraser VJ, Mazuski J, Boyle WA, Buchman TG, Coopersmith CM. The effect of chlorhexidine/silver sulfadiazine-impregnated central venous catheters in an ICU with low bloodstream infection rates following implementation of a successful education program: a before-after trial. Surgical Infections, 8:445-454, 2007. 58. Clark JA, Coopersmith CM. Intestinal crosstalk – a new paradigm for understanding the gut as the “motor” in critical illness. Shock, 28:384-393, 2007. 59. Graham DB, Robertson CM, Bautista J, Diacovo MJ, Montgrain V, Lam SK, Cremasco V, Faccio R, Dunne WM, Coopersmith CM, Swat W. Neutrophil-mediated oxidative burst and host defense against Staphylococcal pneumonia and Pseudomonas aeruginosa are controlled by a vav-PLCγ2 signaling axis. Journal of Clinical Investigation, 117:3445-3452, 2007. 60. Rajan S, Vyas D, Clark A, Woolsey CA, Clark JA, Hotchkiss RS, Buchman TG, Coopersmith CM. Intestine-specific overexpression of IL-10 improves survival in polymicrobial sepsis. Shock, 29:483-489, 2008. 61. Clark JA, Clark AT, Hotchkiss RS, Buchman TG, Coopersmith CM. Epidermal growth factor treatment decreases mortality and is associated with improved gut integrity in sepsis. Shock, 30:36-42, 2008. 62. Schwulst SJ, Muenzer JT, Chang KC, Brahmbatt TS, Coopersmith CM, Hotchkiss RS. Lymphocyte phenotyping to distinguish septic from nonseptic critical illness. J Am Coll Surg. 206:335-342, 2008. 63. McDunn JE, Husain KD, Polpitiya AD, Burykin A, Rua J, Zhang W, Coopersmith CM, Dunne WM, Colonna M, Ghosh B, Stormo GD, Cobb JP. Plasticity of the systemic inflammatory response to critical illness, PloS One, 13:3,e1564, 2008. 64. Robertson TR, Sona C, Schallom ME, Buckles M, Cracchiolo L, Schuerer DJE, Coopersmith CM, Song F, Buchman TG. Increase in extubation rates with implementation of a daily spontaneous breathing trial protocol. Journal of the American College of Surgeons, 206:489-495, 2008. 65. Schuerer DJE, Kolovos NS, Boyd KV, Coopersmith CM. Extracorporeal memberane oxygenation: current clinical practice, coding and reimbursement. Chest, 134:179-184, 2008. 66. Freeman BD, Kennedy C, Robertson E, Coopersmith CM, Schuerer DJE, Buchman TG. Tracheostomy protocol: experience with development and potential utility Critical Care Medicine, 36:1742-1748, 2008. 67. Robertson CM, McConnell KW, Dunne WM, Boody B, Brahmbhatt T, Diacovo MJ, Van Rooijen N, Hogue LA, Cannon CL, Buchman TG, Hotchkiss RS, Coopersmith CM. Neutrophil Depletion Causes a Fatal Defect in Murine Pulmonary Staphylococcus aureus Clearance. Journal of Surgical Research, 150:278-85, 2008. 68. Checchia PA, Schierding W, Polpitiya A, Dixon D, MacMillan S, Muenzer J, Coopersmith CM, Buchman TG, Cobb TG. Myocardial transcriptional profiles in a murine model of sepsis: evidence for the importance of age. Pediatric Critical Care Medicine, 9:530-5, 2008. 69. Freeman BD, Dixon DJ, Coopersmith CM, Zehnbauer BA, Buchman TG. Pharmacoepidemiology of QT-prolonging drug administration in critically ill patients, Pharmacoepidemiology and Drug Safety, 17:971-81, 2008. 70. Sona CS, Zack JE, Schallom ME, McSweeney M, McMullen K, Thomas J, Coopersmith CM, Boyle WA, Buchman TG, Mazuski JE, Schuerer DJE. The impact of a simple, low-cost oral care protocol on ventilator-associated pneumonia rates in a surgical intensivce care unit, Journal of Intensive Care Medicine, 24:54-62, 2009. 71. Robertson CM, Klingensmith ME, Coopersmith CM. Prevalence and cost of full-time research fellowships during general surgery residency – a national survey, Annals of Surgery, 249:155-161, 2009. Reply to letter to the editor regarding this manuscript in press, Annals of Surgery. 72. Fox AC, Coopersmith CM. Erythropoietin in sepsis: a new use for a familiar drug? Critical Care Medicine, 37:1138-1139, 2009. 73. Goede MR, Coopersmith CM. Catheter-related bloodstream infection. Surgical Clinics of North America, 89:463-474, 2009 74. Turnbull IR, Clark AT, Stromberg PE, Dixon DJ, Woolsey CA, Davis CG, Hotchkiss RS, Buchman TG, Coopersmith CM. Effects of aging on the immunopathological response to sepsis, Critical Care Medicine, 37:1018-1023, 2009. 75. Stromberg PE, Woolsey CA, Clark AT, Clark JA, Turnbull IR, McConnell KW, Chang KC, Chung C, + Ayala A, Buchman TG, Hotchkiss RS, Coopersmith CM. CD4 lymphocytes control gut epithelial apoptosis and mediate survival in sepsis, FASEB Journal, 23: 1817-1825, 2009. 76. Hotchkiss RS, Coopersmith CM, McDunn JE, Ferguson TA, Immunosuppression in critical illness mechanistic insights, Nature Medicine, 15: 496-497, 2009. 77. Brahmamdam P, Watanabe E, Unsinger J, Dixon D, Hoekzema A, Zhou T, Chang KC, McDonough J, Holemon H, Heidel JD, Coopersmith CM, McDunn JE, Hotchkiss RS Targeted delivery of siRNA to cell death proteins in sepsis. Shock, 32:131-9, 2009. 78. Byrnes MC, Schuerer DJE, Schallom ME, Sona CS, Mazuski JE, Taylor BE, McKenzie W, Thomas JT, Emerson JS, Nemeth JL, Bailey RA, Boyle WA, Buchman TG, Coopersmith CM. Implementation of a mandatory checklist of protocols and objectives improves compliance with a wide range of evidencebased ICU practices, Critical Care Medicine, 37: 2775-2785, 2009. 79. Freeman BD, Kennedy C, Coopersmith CM, Buchman TG. Examination of patient-independent factors affecting tracheostomy practice in an academic surgical intensive care unit, Critical Care Medicine, 37: 3070-3078, 2009. 80. Clark JA, Gan H, Samocha AJ, Fox AC, Buchman TG, Coopersmith CM. Enterocyte-specific epidermal growth factor prevents barrier dysfunction and improves mortality in murine peritonitis, American Journal of Physiology Gastrointestinal and Liver Physiology, 297:G471-9, 2009. 81. McConnell KW, McDunn JE, Clark AT, Dunne WM, Dixon DJ, Turnbull IR, DiPasco PJ, Osberghau WF, Sherman B, Martin JR, Walter MJ, Cobb JP, Buchman TG, Hotchkiss RS, Coopersmith CM. Streptococcus pneumoniae and Pseudomonas aeruginosa pneumonia induce distinct local and systemic inflammatory host responses, Critical Care Medicine, 38: 233-241, 2010. 82. Fox AC, Robertson CM, Belt B, Clark AT, Chang KC, Leahtersich AM, Dominguez JA, Perrone EE, Dunne WM, Hotchkiss RS, Buchman TG, Linehan DC, Coopersmith CM. Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis, Critical Care Medicine, e pub ahead of print. 83. Inoue S, Unsinger J, Davis CG, Muenzer JT, Ferguson TA, Clark AT, Coopersmith CM, McDunn JE, Hotchkiss RS. IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis, Journal of Immunology, 184:1401-1409, 2010. 84. Muenzer JT, Davis CG, Chang K, Schmidt RE, Dunne WM, Coopersmith CM, Hotchkiss RS. Characterization and modulation of the immunosuppressive phase of sepsis. Infection and Immunity, 78:1582-1592, 2010. 85. Honda H, Krauss MJ, Coopersmith CM, Kollef MH, Richmond AM, Fraser VJ, Warren DK, Staphylococcus aureus Colonization and Subsequent Infection in Intensive Care Unit Patients: Does Methicillin Resistance Matter, Infection Control and Hospital Epidemiology, 31:584-591, 2010. 86. Dominguez, JA, Coopersmith CM, Can We Protect the Gut in Critical Illness: The Role of Growth Factors and Other Novel Approaches, Critical Care Clinics, 26:549-565, 2010. 87. McConnell KW, Fox AC, Clark AT, Chang NN, Dominguez JA, Farris AB, Buchman TG, Hunt CR, Coopermsith CM. The role of HSP70 in mediating age-dependent mortality in sepsis, Journal of Immunology, 186:3718-3725, 2011 88. Pastores SM, O’Connor MF, Kleinpell RM, Napolitano L, Ward N, Bailey H, Mollenkopf FP, Coopersmith CM. The ACGME Resident Duty-Hour New Standards: History, Changes, and Impact on Staffing of Intensive Care Units, Critical Care Medicine, 39:2540-2549, 2011. 89. Dominguez JA, Vithayathil, PJ, Khailova L, Lawrance CP, Samocha AJ, Jung E, Leathersich AM, Dunne WM, Coopersmith CM. EGF enhances intestinal epithelial integrity and improves survival in Pseudomonas aeruginosa pneumonia, Shock, 36:381-389, 2011. 90. Fox AC, Breed ER, Liang Z, Clark AT, Zee-Cheng BR, Chang KC, Dominguez JA, Jung E, Dunne WM, Burd EM, Farris AB, Linehan DC, Coopersmith CM. Prevention of lymphocyte apoptosis in septic mice with cancer increases mortality, Journal of Immunology, 187:1950-1956,2011. 91. Carpenter CR, Griffey RT, Stark S, Coopersmith CM, Gage BF, Physician and Nurse Acceptance of Geriatric Technicians to Screen for Geriatric Syndromes in the Emergency Department, Western Journal of Emergency Medicine, 12:489-495, 2011. 92. Jung E, Perrone EE, Liang Z, Breed ER, Dominguez JA, Clark AT, Fox AC, Dunne WM, Burd EM, Farris AB, Hotchkiss RS, Coopersmith CM. Cecal ligation and puncture followed by MRSA pneumonia increases mortality in mice and blunts production of local and systemic cytokines, Shock, 37: 85-94,2012. 92. Coopersmith CM, Wunsch, H,. Fink MP, Linde-Zwirble WT, Olsen KM, Sommers,MS, Anand KJS, Kingsmore SF, Tchorz KM, Angus, DC, Deutschman CS, A comparison of critical care research funding and the financial burden of critical illness in the United States, Critical Care Medicine, 40:1072-1079, 2012. 93. McConnell KW, Coopersmith CM. Organ failure avoidance and mitigation strategies, Surgical Clinics of North America, 92:307-319, 2012. 94. Carpenter DL, Gregg SR, Owens DS, Buchman TG, Coopersmith CM. Documentation of patient care time by nurse practitioners and physician assistants in the intensive care unit, Critical Care, 16:R27, 2012. 95. Perrone EE, Jung E, Dominguez JA, Clark AT, Dunne WM, Burd E, Hotchkiss RS, Buchman TG, Coopersmith CM. Mechanisms of methicillin-resistant Staphylococcus aureus pneumonia-induced intestinal epithelial apoptosis, submitted. 96. Ingram TC, Kamat P, Coopersmith CM, Vats A. Intensivist’s perceptions of family centered rounds and its impact on physician comfort, staff involvement, teaching and efficiency, submitted. 97. Dominguez JA, Samocha AJ, Coopersmith CM. Inhibition of NF-κB in enterocytes exacerbates sepsis-induced intestinal injury and worsens mortality, submitted. 98. Dominguez JA, Xie Y, Dunne WM, Coopersmith CM, Davidson NO. Intestine-specific Mttp deletion decreases mortality and prevents sepsis-induced intestinal injury in a model of Pseudomonas aeruginosa pneumonia, submitted. 99. Benton SM, Liang Z, Hao L, Hebba G, Jones DP, Coopersmith CM, Ziegler TR. Differential regulation of tissue thiol-disulfide redox status in a murine model of peritonitis, submitted. 100. Tisherman SA, Kaplan L, Gracias V, Coopersmith CM, Beilman G, Toevs C, Byrnes MC. Providing care for critically ill surgical patients: challenges and recommendations, submitted. Book Chapters 1. Coopersmith CM, Moley JF. (1996) The Spleen. In: The Washington Manual of Surgery (D. Baumann, L. Creswell, G. Doherty, J. Goss, T. Lairmore, editors), Little, Brown and Company, pp. 280-286.. 2. Coopersmith CM, Kodner IJ. (1999) Colon, rectum, and anus. In: The Washington Manual of Surgery (G. Doherty, J. Meko, J. Olson, G. Peplinski, N. Worrall, editors), Little, Brown and Company, pp. 236-258.. 3. Stromberg PE, Coopersmith CM. (2003) Proliferation of the gastrointestinal epithelium. In Encyclopedia of Gastroenterology (L. Johnson, editor), Elsevier, pp. 725-730.. 4. Coopersmith CM, Buchman TG. (2004) Perioperative care and monitoring of the surgical patient. In Current Surgical Therapy (J. Cameron, editor), Mosby pp. 1105-1111.. 5. Coopersmith CM, Kollef MH. (2004) Post-operative and ventilator-associated pneumonia. In ACS Surgery Online (WW Souba, MP Fink, GJ Jurkovich et al editors). Chapter 18. WebMed Inc, New York. http://www.acssurgery/.September 2004. 6. Husain KD, Coopersmith CM. (2005) Acute renal failure. In Complications in General Surgery (G. Doherty, M. Mulholland, editors). Lippincott Wilkins and Williams, pp. 150-156. 7. Chung P, Coopersmith CM. (2005) Critical Care. In: The Washington Manual of Surgery (K. Amos, D. Green, S. Hunt, V. Halpin, M. Klingensmith, editors), Little, Brown and Company. pp. 177-196 8. Coopersmith CM, Babcock HM, Zack JE, Cobb JP. Infection control in the intensive care unit. In: Surgical Infections (D. Fry, editor). Little, Brown and Company, Boston, In press. 9. Coopersmith CM, Kollef MH. (2005) 18 Post-operative and ventilator-associated pneumonia. 7 Critical Care. In ACS Surgery Online (WW Souba, MP Fink, GJ Jurkovich et al editors). WebMed Inc, New York. http://www.acssurgery/.August 2005 (update of chapter #5) 10. Coopersmith CM. (2006) Molecular foundations of cellular injury: Apoptosis and necrosis. In Pediatric Critical Care (B. Fuhrman and J. Zimmerman, editors). Mosby, pp. 1444-1452. 11. Coopersmith CM, Buchman TG. (2007) Perioperative management of the emergency surgery patient: the ICU and the intensivist. In Acute Care Surgery Principles and Practice (L. Britt, D. Trunkey, D. Feliciano, editors). Springer, pp. 67-83. 12. McConnell KW, Kirby J, Coopersmith CM. (2007) Cellulitis/Fasciitis/Myositis. In The Washington Manual of Critical Care (M. Kollef, editor), Lippincott, Williams and Wilkins, pp. 266-270. 13. Fox A, Coopersmith CM. (2008) Hemostasis and transfusion. In: The Washington Manual of Surgery (L Chen, S Glasgow, T Goers, S Melby and M. Klingensmith, editors), Lippincott, Williams and Wilkins, pp. 92-107. 14. Rivet E, Coopersmith CM. (2008) Surgical critical care. In: The Washington Manual of Surgery (L Chen, S Glasgow, T Goers, S Melby and M. Klingensmith, editors), Lippincott, Williams and Wilkins, (update of chapter #7) , pp. 134-152, Philadelphia, PA. 15. Efron PA, Coopersmith CM. (2009) Sepsis. In: Trauma, Surgical Critical Care, and Surgical Emergencies (R. Rabinovici, H. Frankel, O. Kirton, editors), Informa, in press. 16. Nix SA , Coopersmith CM (2009) Selective Decontamination of the Digestive Tract. In EvidenceBased Practice of Critical Care (C. Deutschman, P. Nelligan, editors), in press. 17. Southard RE, Coopersmith CM. (2010) Acute renal failure. In Complications in General Surgery (G. Doherty, M. Mulholland, editors). Lippincott Wilkins and Williams, in press. 18. Muenzer JT, Coopersmith CM. (2010) Molecular foundations of cellular injury: Apoptosis, necrosis, and autophagy. In Pediatric Critical Care (B. Fuhrman and J. Zimmerman, editors). Mosby, pp. 14441452. 19. Dominguez JA, Coopersmith CM (2010) Gut dysfunction. In Encyclopedia of Intensive Care Medicine (JL Vincent and J Hall, editors), Spinger, in press. 20. Coopersmith CM, Kollef MH. (2012) Post-operative and ventilator-associated pneumonia. Critical Care. In ACS Surgery Online (WW Souba, MP Fink, GJ Jurkovich et al editors). WebMed Inc, New York. http://www.acssurgery/.August 2011 (update of chapter #9) 21. Lamm RL, Coopersmith CM (2012) Hypovolemic and Hemorrhagic Shock. In Comprehensive Critical Care Review Book (Roberts, Todd, et al. editors) Society of Critical Care Medicine, pp. 183-198.. 22. McConnell KW, Coopersmith CM (2012) Common cardiac arrythmias. In SCORE, General Surgery Resident Curriculum https://portal.surgicalcore.org/, in press. Invited Presentations: 1. Apoptotic Mechanisms in Shock and Sepsis? Twenty fourth Annual Conference on Shock, Shock Society. Marco Island, FL. June 10, 2001. 2. Intestinal apoptosis in shock and sepsis. IBD Research: Junior Faculty Symposium, Northwestern University, January 12, 2002 3. Prevention of nosocomial gram-positive infections: Daybreak session "New strategies for the prevention and treatment of gram-positive infections in the ICU," 31st Critical Care Congress, Society of Critical Care Medicine, Jan 29, 2002 4. Effect of education programs in preventing nosocomial infections. Department of Medicine Grand Rounds, University of Nebraska, May 24, 2002. 5. Intestinal epithelial apoptosis. 33rd Critical Care Congress, Society of Critical Care Medicine, Orlando, FL, Feb. 22, 2004. 6. Gut epithelial apoptosis and injury. 6th World Congress on Trauma, Shock, Inflammation and Sepsis Pathophysiology, Immune Consequences and Therapy, Munich, Germany March 2-6, 2004. 7. Sepsis induced apoptosis in the gastrointestinal tract. 6th World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich, Germany March 2-6, 2004. 8. Epithelial response to critical illness and stress. 6th World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich, Germany March 2-6, 2004. 9. Role of education in preventing bacteremia. 24th International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, March 30-April 2, 2004. 10. Hypophosphatemia. 24th International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, March 30-April 2, 2004. 11. Manipulating apoptosis. 24th International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, March 30-April 2, 2004. 12. Preventing infections in the critically ill surgical patient. Illinois Surgical Society, Rend Lake, IL, Sept 11, 2004. 13. Good and bad cell death (apoptosis in sepsis). 34th Critical Care Congress, Society of Critical Care Medicine, Phoenix, AZ, Jan 15, 2005 14. Gut epithelial apoptosis in critical illness. 34th Critical Care Congress, Society of Critical Care Medicine, Phoenix, AZ, January 16, 2005 15. The role of education in preventing primary bacteremia. 34th Critical Care Congress, Society of Critical Care Medicine, Phoenix, AZ, January 17, 2005 16. Barrier failure in sepsis: when normal cell death processes go awry. Twenth eighth annual conference on Shock, Shock Society, Marco Island, FL, June 4-7, 2005. 17. Gut epithelial apoptosis and sepsis. Surgical Biology Club II, San Francisco, CA October 15, 2005. 18. Prevention of Catheter-releated bacteremia in the surgical intensive care unit. 162 nd meeting, Society of Clinical Surgery, St. Louis, MO, November 4, 2005. 19. Evidenced medicine and protocol usage in the surgical intensive care unit. Department of Surgery grand rounds. Loma Linda University, November 30, 2005. 20. Antimicrobial impregnated catheters in low infection rates. 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, CA, January 23, 2006. 21. Gut epithelium/bacteria – it is the cause of all inflammation? 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, CA, January 23, 2006. 22 .The gut as the motor of the systemic inflammatory response syndrome. 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, CA, January 25, 2006. 23. The gut in sepsis – a tale of apoptosis, crosstalk and aging. Basic Science Seminar. Department of Surgery and The Burn and Shock Trauma Institute at Loyola University Medical Center, March 22, 2006. 24. All patients with refractory septic shock should get low dose steroid therapy (pro in pro/con debate). th 25 annual meeting of the Surgical Infection Society, San Diego, CA April 29, 2006. 25. Gut apoptosis in sepsis. Ohio State University Critical Care Center. June 23, 2006. 26. Cost of infections and cost-effectiveness of infection control. The 46th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) San Francisco, CA September 27-30, 2006. 27. Prevention of catheter-related bloodstream infections. 92nd annual clinical congress of the American College of Surgeons. Chicago, IL, October 10, 2006. 28. Experience with tight glucose control in the Surgical Intensive Care Unit. 92nd annual clinical congress of the American College of Surgeons. Chicago, IL, October 11, 2006. 29. The use of anti-apoptotic agents following injury. American Heart Association Resuscitative Science Symposium. Chicago, IL November 10, 2006. 30. Interactions between the gut epithelium and the adaptive immune system in sepsis. 36th Critical Care Congress, Society of Critical Care Medicine, Orlando, FL, February 19, 2007. 31. The promise of apoptosis inhibition and barriers to therapeutic implementation. 7th World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich, Germany March 14. 2007. 32. Is it possible to preserve and protect the mucosa in critical illness? 7th World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich, Germany March 14. 2007. 33. Prevention of catheter-related bloodstream infections. American Association of Surgical Physician Assistants, New Orleans, LA Oct. 6, 2007. 34 Intestinal apoptosis and the pathophysiology/treatment of sepsis. Department of Surgery grand rounds. Medical College of Georgia, November 26, 2007. Also evening conference Infection Control in the ICU. st 35. NIH – Basic Science Research Funding. 21 Annual Congress Eastern Association for the Surgery of Trauma, Amelia Island Plantation, FL January 15, 2008. 36. Pseudomonas aeruginosa and Streptococcus pneumoniae and the host inflammatory response. 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008. 37. Aging and the host response to sepsis. 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008. 38. Funding At Mid-career: Getting Past The K Award. 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008. 39. Catheter-related bloodstream infection. Association of Perioperative Registered Nurses – Puerto Rico Chapter, San Juan, PR, Feb 22, 2008. 40. Cathter-related bloodstream infection. Integrating pulmonary and critical care medicine into clinical practice. Creighton University, Omaha, NE April 4, 2008. 41. Trauma patients. Integrating pulmonary and critical care medicine into clinical practice. Creighton University, Omaha, NE April 4, 2008. 42. EGF in Sepsis: Finally a Molecule to Protect the Injured Gut? 38th Critical Care Congress, Society of Critical Care Medicine, Nashville, TN January 30-February 4, 2009. 43. Gut Epithelial Apoptosis and Sepsis Chiba University Medical School, Chiba University, Chiba Japan, November 2, 2009. 44. EGF in Sepsis: A Molecule to Protect the Injured Gut? And Infection Control and Patient Safety in the ICU. Juntendo University and Tokyo Medical School, Tokyo, Japan, November 4, 2009. 45. EGF in Sepsis: A Molecule to Protect the Injured Gut? And Infection Control and Patient Safety in the ICU. Osaka University Medical School, Osaka, Japan, November 7, 2009. 46. Motivating 80 Hour Residents to be 100 Hour Attendings. 39th Critical Care Congress, Society of Critical Care Medicine, Miami, FL February, 2010. 47. The roles of lymphocytes and apoptosis in the modulation of intestinal inflammation. 8th World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich, Germany March 9-13, 2010. 48. Death of gastrointestinal epithelial cells in sepsis and trauma. 8th World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich, Germany March 9-13, 2010. 49. Gut Epithelial Apoptosis and Sepsis. Also second talk: The Gut in Sepsis: Concepts, Opportunities, Challenges, University of Chicago, August 4-5, 2010. 50. Aging and the host response to sepsis. Also second talk: Gut epithelial integrity in sepsis, University of Pennsylvania, December 1-2, 2010 51. Role of Cell Death, 40th Critical Care Congress, Society of Critical Care Medicine, San Diego, CA January 16, 2011. st 52. The gut: can we protect the gut in critical illness. 41 Critical Care Congress, Society of Critical Care Medicine, Houston, TX , Feb 4-8, 2012. 53. A comparison of critical care research funding and the financial burden of critical illness in the United st States. 41 Critical Care Congress, Society of Critical Care Medicine, Houston, TX , Feb 4-8, 2012. th 54. Infection control. Surgical Critical Care Board Review at the 98 Annual Clinical Congress of the American College of Surgeons, Chicago, IL September 30, 2012. Scientific Presentations 1. Coopersmith CM, Chandrasekaran C, Gordon JI. Studies in transgenic mice reveal that p53 is required for SV40 T Antigen and human K-ras Val12 to cooperate to produce dysplasia in villus- associated intestinal enterocytes. Presented to the American College of Surgeons 81st Annual Clinical Congress, New Orleans, LA, October 24, 1995. 2. Coopersmith CM, Chandrasekaran C, Gordon JI. K-ras Val12 causes a p53-independent increase in apoptosis in proliferating villus-associated enterocytes in transgenic mice. Presented to the American Association for Cancer Research Special Conference on Cancer Susceptibility Genes and Molecular Carcinogenesis. Keystone, CO, February 23, 1996. 3. Coopersmith CM, Chandrasekaran C, Gordon JI. Radiation-induced apoptosis in the small intestine of transgenic mice: additional evidence for cell nonautonomous regulation. Presented to the American Society for Clinical Investigation in conjunction with Science Magazine Biomedicine ‘96 Medical Research from Bench to Bedside. Washington, D.C., May 6, 1996. 4. Coopersmith CM, Brennan DC, Miller B, Shenoy S, Ramachandran V, Mohanakumar T, Ceriotti CS, Howard TK, Lowell JA. Renal transplantation following previous solid organ transplantation: an 8-year single-center experience. Presented to Transplant 2000, Joint meeting of American Society of Transplantation and American Society of Transplant Surgeons. Chicago, IL, May 16, 2000. Also presented at St. Louis Surgical Society. St. Louis, MO, January 17, 2000. 5. Wizorek JJ, Cobb JP, Qui Y, Laramie J, Coopersmith CM, Hotchkiss RS, Karl I.E, Buchman TG. Heat shock paradox: subsequent heat shock increases lethality of polymicrobial sepsis in vivo. Presented to st 21 International Symposium on Intensive Care and Emergency Medicine, Brussels, March 20-23, 2001. 6. Tinsley K, Swanson P, Coopersmith C, Wagner T, Schmieg R, Chang K, Osborne D, Freeman B, Cobb J, Buchman T, Karl I, Hotchkiss R. Sepsis causes loss of CD3 T cells, B cells, and lymphoid follicles. Presented to the Twenty fourth Annual Conference on Shock, Shock Society. Marco Island, FL. June 9-12, 2001. 7. Coopersmith CM, Stromberg PE, Dunne WM, Davis CG, Buchman TG, Hotchkiss RS. Overexpression of Bcl-2 in the intestinal epithelium improves survival in a model of pseudomonas pneumonia-induced sepsis. Presented to the 31st Critical Care Congress, Society of Critical Care Medicine, San Diego CA, Jan 26-30, 2002. 8. Taylor B, Huey W, Coopersmith C, Buchman T. Clinical effectiveness of a phosphorus repletion protocol in a surgical intensive care unit. Presented to the 31st Critical Care Congress, Society of Critical Care Medicine, San Diego CA, Jan 26-30, 2002. 9. Coopersmith CM, Stromberg PE, Davis CG, Dunne WM, Amiot DM, Karl IE, Hotchkiss RS, Buchman TG. Sepsis from Pseudomonas aeruginosa pneumonia induces gut epithelial cell cycle arrest. Presented to the 25th Annual Conference on Shock, Shock Society, Big Sky, Montana June 9, 2002. 10. Husain KD, Stromberg PE, Dunne WM, Turnbull IR, Hotchkiss RS, Karl IE, Buchman TG, Coopersmith CM, Acute lung injury causes increased gut epithelial apoptosis and decreased proliferation in mice. Presented to the 32nd Critical Care Congress, Society of Critical Care Medicine,San Antonio, TX, Jan 28 - Feb 2, 2003. 11. Javadi P, Turnbull IR, Coopersmith CM, Hotchkiss RS, Buchman TG. Aging is associated with increased IL-6 and splenic apoptosis following cecal ligation and puncture. Presented to the 32nd Critical Care Congress, Society of Critical Care Medicine,San Antonio, TX, Jan 28 - Feb 2, 2003. 12. Taylor BE, Huey W, Buchman TG, Boyle WA, Coopersmith CM. Clinical Effectiveness of a nurse driven insulin infusion protocol in the surgical ICU. Presented to the 32nd Critical Care Congress, Society of Critical Care Medicine,San Antonio, TX, Jan 28 - Feb 2, 2003. (Research citation award winner). 13. Husain KD, Amiot DM, Stromberg PE, Davis CG, Dunne WM, Buchman TG, Karl IE, Hotchkiss RS, Coopersmith CM. Streptococcus Pneumoniae infection in mice: apoptosis and survival. Presented to the 23rd Annual Meeting, Surgical Infection Society, San Antonio. TX, April 10-12, 2003. 14. Coopersmith CM, Zack JE, Ward MR, Schallom ME, Sona CS, Huey WY, Buchman TG, Boyle WA, Fraser VJ, Polish LB. Education alters behavior and impacts catheter-related bloodstream infection rates in the surgical ICU. Presented to the 23rd Annual Meeting, Surgical Infection Society, San Antonio. TX, April 10-12, 2003 (finalist for best abstract competition). 15. Turnbull IR, Javadi P, Coopersmith CM, Hotchkiss RS, Buchman TG. IL-6 predicts septic mortality in ND4 mice and antibiotics fail to rescue septic mice with high IL-6. Presented to the 23rd Annual Meeting, Surgical Infection Society, San Antonio. TX, April 10-12, 2003. 16. Schallom ME, Coopersmith CM, Sona CS, Huey WY, Taylor BT. Keepting rotating residents in the loop. Presented to the National Teaching Institute for the American Association of Critical Care Nurses, San Antonio, TX, May 17-22, 2003. 17. Husain KD, Stromberg PE, Javadi P, Amio DM, Buchman TG, Karl IS, Hotchkiss, Coopersmith CM. Bcl-2 inhibits gut epithelial apoptosis but does not improve survival in acute lung injury. Presented to the 26th Annual Conference on Shock, Shock Society, Phoenix, AZ June 7-10, 2003 (young investigator award finalist). 18. Stromberg PE, Turnbull IR, Chang KC, Husain KD, Hotchkiss, RS, Buchman TG, Coopersmith CM. Lymphocytes alter gut epithelial proliferation but not apoptosis in sepsis. Presented to the 26th Annual Conference on Shock, Shock Society, Phoenix, AZ June 7-10, 2003. 19. Husain KD, Stromberg PE, Woolsey CA, Hotchkiss WR, Buchman TG, Hotchkiss RS, Karl IE, Coopersmith CM. Altered gut epithelial apoptosis and proliferation in acute lung injury: the roles of Bcl-2, TLR4, and TNF-alpha. Presented to the 33rd Critical Care Congress, Society of Critical Care Medicine, Orlando, FL , Feb 22-25, 2004. 20. Husain KD, Stromberg PE, Woolsey CA, Turnbull IR, Buchman TG, Karl IE, Hotchkiss RS, Coopersmith CM. Lung injury uncouples gut apoptosis and proliferation. Presented to the 6th World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich, Germany March 2-6, 2004. 21. Javadi P, Stromberg PE, Husain KD, Woolsey CA, Buchman TG, Karl IE, Hotchkiss RS, Coopersmith CM. Exogenous iron after sepsis increases mortality and alters apoptosis. Presented to the 6th World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich, Germany March 2-6, 2004. 22. Stromberg PE, Chang KC, Woolsey CA, Hotchkiss WR, Buchman TG, Karl IE, Hotchkiss RS, Coopersmith CM. Gut overexpression of Bcl-2 requires lymphocytes to improve survival. Presented to the 6th World Congress on Trauma, Shock, Inflammation and Sepsis - Pathophysiology, Immune Consequences and Therapy, Munich, Germany March 2-6, 2004. 23. Warren DK, Jones RM, Coopersmith CM, Seiler SM, Merz LR, Zack JE, Ward MR, Fraser VJ. The Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Surgical Intensive Care Unit. Presented to the 14th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America, Philadelphia, PA, April 17-20, 2004. 24. Woolsey CA, Stromberg PE, Javad P, Husain KD, Chang KC, Hotchkiss RS, Karl IE, Buchman TG, Coopersmith CM. The adaptive immune system mediates gut epithelial apoptosis following cecal ligationa and puncture. Presented to the 27th Annual Conference on Shock, Shock Society, Halifax, Canada June 5-8, 2004 (travel awardee). 25. Stromberg PE, Woolsey CA, Husain KD, Dunne WM, Buchman TG, Karl IE, Hotchkiss RS, Coopersmith CM, Mice expressing caspase-3 resistant retinoblastoma protein have decreased gut epithelial but not splenic apoptosis in Pseudomonas aeruginosa pneumonia. Presented to the 27th Annual Conference on Shock, Shock Society, Halifax, Canada June 5-8, 2004 (travel awardee). 26. Husain KD, Stromberg PE, Woolsey CA, Dunne WM, Buchman TG, Karl IE, Hotchkiss RS, Coopersmith CM, Gut epithelial apoptosis occurs via the mitochondrial and receptor-mediated pathways in Streptococcus pneumoniae pneumonia. Presented to the 27th Annual Conference on Shock, Shock Society, Halifax, Canada June 5-8, 2004 (travel awardee). 27. Javadi P, Buchman TG, Turnbull IR, Stromberg PE, Coopersmith CM. Gut epithelial and splenic apoptosis in septic Hfe-/- mice are age dependent. Presented to the 27th Annual Conference on Shock, Shock Society, Halifax, Canada June 5-8, 2004. 28. Warren DK, Jones RM. Coopersmith CM, Seiler SM, Merz LR, Zack JE, Ward MR, Fraser VJ. The Impact of an Active Surveillance Program on MRSA Detection and Contact Precaution Utilization in a Surgical Intensive Care Unit. Presented to the 42nd Annual Meeting of the Infectious Diseases Society of America, Boston, MA, September 30 - October 3, 2004 29. McDunn JE, Husain KD, Coopersmith CM, Townsend RR, Cobb JP. Comparison of the plasma proteome during Gram-positive and Gram-negative pneumonia in mice. Presented to the American College of Surgeons 81st Annual Clinical Congress, New Orleans, LA, October 10-14, 2004. 30. Buchman TG, Taylor BE, Coopersmith CM. The journey from literature evidence to clinical protocol. Presented to the World Shock Forum, Tokyo, Japan, October 30, 2004. 31. Freeman BD, Kennedy CM, Coopersmith CM, Zehnbauer BA, Buchman TG. Perceptions and attitudes of genetic research held by surrogate decision makers for critically ill patients. Presented to 2004 Office of Research Integrity Research Conference on Research Integrity, San Diego, CA, November 1214, 2004. 32. McConnell KW, DiPasco PJ, Turnbull IR, Dunne WM, Buchman TG, Hotchkiss RS, Karl IE, Coopersmith CM. Pathobiological comparison of gram positive and gram negative murine pneumonia. Presented to the 34th Critical Care Congress, Society of Critical Care Medicine, Phoenix, AZ, January 1619, 2005. 33. Woolsey CA, Dunne WM, Hotchkiss RS, Buchman TG, Karl IE, Coopersmith CM. The relationship between gut epithelial apoptosis and proliferation in sepsis is dependent on mortality but independent on type of infection. Presented to the 34th Critical Care Congress, Society of Critical Care Medicine, Phoenix, AZ, January 16-19, 2005. 34. Taylor B, Huey W, Buchman T, Boyle W, Ward M, Schallom L, Sona C, Zack J, Thomas J, Mazuski J, Kaiser K, Coopersmith C. Clinical effectiveness of a nurse driven insulin infusion protocol with a target range of 80-100 mg/dl. Presented to the 34th Critical Care Congress, Society of Critical Care Medicine, Phoenix, AZ, January 16-19, 2005. 35. Husain KD, Polpitya A, McDunn J, Tong A, MacMillan S, Coopersmith CM, Cobb JP. Untangling pneumonia from inflammation: leukocyte microarray gene expression profiles can diagnose pneumonia and distinguish between causative bacteria. Presented to the 34th Critical Care Congress, Society of Critical Care Medicine, Phoenix, AZ, January 16-19, 2005 (Educational award winner). 36. DiPasco PJ, Chang KC, Davis CG, Unsinger J, Ferguson TA, Karl IE, Coopersmith CM, Hotchkiss RS. CD40 Ligand protects against sepsis induced B-cell apoptosis. Presented to the 34th Critical Care Congress, Society of Critical Care Medicine, Phoenix, AZ, January 16-19, 2005. 37. Vyas D, Javadi P, DiPasco PJ, Buchman TG, Hotchkiss RS, Karl IE, Coopersmith CM. Early antibiotic therapy, but not anti-IL-6 antibody, rescue mice predicted to die by high IL- 6 levels in sepsis. th Presented to the 66 annual meeting of the Society of University Surgeons, Nashville, TN, February 10, 2005. 38. Adams SR, Warren DK, Jones RM, Coopersmith CM, Seiler SM, Merz LR, Zack JE, Ward MR, Fraser VJ. The epidemiology of methicillin-sensitive and methicillin-resistant Staphylococcus aureus in a th surgical intensive care unit. Presented to the 15 annual meeting of the Society for Healthcare Epidemiology of America, Los Angeles, CA, April 10, 2005. 39. Warren DK, Jones RM, Coopersmih CM, Merz LR, Zack JE, Fraser VJ. Contact Precaution th Utilization in a Surgical Intensive Care Unit. Presented to the 15 annual meeting of the Society for Healthcare Epidemiology of America, Los Angeles, CA, April 10, 2005. 40. McConnell KW, DiPasco PJ, Turnbull IR, Dunne WM, Buchman TG, Hotchkiss RS, Karl IE, Coopersmith CM. Pathobiological comparison of high and intermediate mortality Pseudomonas murine th pneumonia. Presented to the 25 annual meeting of the Surgical Infection Society, Miami, FL, May 5, 2005. 41. McConnell, KW, DiPasco P, Chang K, Schreiber T, Vyas D, Dunne WM, Buchman TG, Hotchkiss RS, Coopersmith CM. Gram positive and gram negative murine pneumonia induce unique changes in th lymphocyte apoptosis and neutrophil migration. Presented to the 28 annual conference on Shock, Shock Society, Marco Island, FL, June 4-7, 2005. 42. Brookmeyer PR, Jones R, Coopersmith CM, Fraser VJ, Schuerer DJE, Zack J, Warren DK. Risk Factors associated with Catheter-associated Bloodstream Infections in a Surgical Intensive Care Unit. Presented to the 43rd Annual Meeting of the Infectious Diseases Society of America, San Francisco, CA, October 6-9, 2005. 43. Checchia PA, Polpitiya A, MacMillan S, Stromberg P, Coopersmith CM, Buchman TG, Cobb JP. The Effect of Age on Myocardial Gene Expression Profiles in a Murine Model of Sepsis. Presented to the 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006. 44. Rajan S, Vyas D, Hotchkiss RS, Buchman TG, Coopersmith CM. Intestine Specific Overexpression of IL-10 Improves Survival in a Polymicrobial Model of Sepsis. Presented to the 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006. 45. Woolsey CA, McConnell KW, Martin J, Boody B, Hotchkiss RS, Karl IE, Coopersmith CM. TLR4 Signaling Changes White Blood Cell Distribution in Pseudomona pneumonia. Presented to the 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006. 46. McConnell KW, Chang K, Wagner T, Coopersmith CM, Hotchkiss RS. Peptide transduction domain delivery of anti-apoptotic proteins decreases E. coli induced apoptosis in human lymphocytes. Presented to the 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006. 47. Robertson CM, Stromberg PE, Vyas D, Martin J, Sherman B, Hotchkiss RS Buchman TG, Coopersmith CM. Identifying the optimal method to quantify gut apoptosis in critical illness. Presented to the 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006. 48. Sona C, Zack J, Schallom L, Schwartkopf L, Huey W, McSweeney M, McMullen K, Mazuski J, Schuerer D, Coopersmith C, Boyle W, Buchman T. A simple, low-cost oral care protocol reduces ventilator-associated pneumonia rates. Presented to the 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006. 49. Wagner TH, McConnel KW, Chang KC, Dunne JC, Yuan KZ, Cobb JP, Karl IE, Coopersmith CM, Hotchkiss RS. Gene expression analysis of E. coli induced apoptosis of human lymphocytes and the protective effect of Tat-BH4. Presented to the 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006. 50. Schwulst SJ, Davis C, Chang K, Dunne WM, Serber D, Zhou TT, Coopersmith C, Karl I, Hotchkiss R. Bim-/- mice have nearly complete protection against lymphocyte apoptosis and improved survival in septic peritonitis. Presented to the 35th Critical Care Congress, Society of Critical Care Medicine, San Francisco, January 8-11, 2006. 51. Merz LR, Guth RM, Woeltje KF, Camins BC, Kollef MH, Coopersmith CM, Fraser VJ. The cost of vancomycin-resistant entorococci bloodstream infections in intensive care unit populations. Presented to th the 16 annual meeting of the Society of Healthcare Epidemiology of America, Chicago, IL, March 18-21, 2006. 52. Woeltje KF, Merz LR, Guth RM, Camins BC, Kollef MH, Coopersmith CM, Fraser VJ. Attributable th cost of antimicrobial resistance in gram-negative bacteremia. . Presented to the 16 annual meeting of the Society of Healthcare Epidemiology of America, Chicago, IL, March 18-21, 2006. 53. Guth RM, Merz LR, Woeltje KF, Camins BC, Olsen MA, Georgantopoulos P, Coopersmith CM, Kollef MH, Fraser VJ. The attributable cost of methicillin-resistant Staphylococcus aureus bloodstream th infections. Presented to the 16 annual meeting of the Society of Healthcare Epidemiology of America, Chicago, IL, March 18-21, 2006. 54. McConnell KW, Chang KC, Coopersmith CM, Piwnica-Worms D, Hotchkiss RS. Peptide transduction domain delivery of anti-apoptotic compounds decreases radiation-induced apoptosis in human th lymphocytes. Presented to the 26 annual meeting of the Surgical Infection Society, LaJolla CA, April 2729, 2006. 55. Clark AT, McConnell, KW, Hunt CR, Buchman TG, Hotchkiss RS, Coopersmith CM. HSP 70.1 and HSP70.3 mediate survival following cecal ligation and puncture in aged male mice. Presented to the th 29 annual conference on Shock, Shock Society, Broomfield, CO, June 3-6, 2006 (travel awardee). 56. Rajan S, Woolsey CA, Hotchkiss RS, Buchman TG, Coopersmith CM. An examination of mechanisms underlying the survival benefit conferred by intestine-specfic overexpression of interleukinth 10. Presented to the 29 annual conference on Shock, Shock Society, Broomfield, CO, June 3-6, 2006. 57. Woolsey CA, Stromberg PE, Hotchkiss RS, Buchman TG, Coopersmith CM. Aged mice have altered cytokine profiles and intestinal permeability following cecal ligation and puncture. Presented to the 29 th annual conference on Shock, Shock Society, Broomfield, CO, June 3-6, 2006. 58. McConnell K, Dunne WM, Buchman TG, Hotchkiss RS, Coopersmith CM. Gram positive and gram th negative murine pneumonia induce unique local cytokine profiles. Presented to the 29 annual conference on Shock, Shock Society, Broomfield, CO, June 3-6, 2006. th 59. Turnbull I, Buchman T, Coopersmith CM. Modeling aging and sepsis. Presented to the 29 annual conference on Shock, Shock Society, Broomfield, CO, June 3-6, 2006. 60. Piel DA, Gruber PJ, Weinheimer CJ, Courtois MR, Robertson CM, Coopersmith CM, Deutschman, Levy RJ. Mitochondrial resusciation with exogenous cytochrome C in the septic heart. Presented to the th 29 annual conference on Shock, Shock Society, Broomfield, CO, June 3-6, 2006. 61. Robertson CM, Klingensmith ME, Coopersmith CM. Long-term outcomes of performing laboratory research during surgical residency. Presented to the 92nd annual clinical congress of the American College of Surgeons. Chicago, IL, October 11, 2006. 62. Robertson TE, Cracchilo L, Buckles M, Schallom L, Sona C, Fine S, Schuerer D, Coopersmith CM, Buchman TG. Increase in extubation rate with implementation of daily spontaneous breathing trials. Presented to the 36th Critical Care Congress, Society of Critical Care Medicine, Orlando, FL, February 17-21, 2007. 63. Robertson CM, Martin J, Boody B, Dunne WM, Hotchkiss R, BuchmanT, Coopersmith CM. Neutrophil depletion allows creation of a virulent model of staphylococcus aureus pneumonia. Presented to the 36th Critical Care Congress, Society of Critical Care Medicine, Orlando, FL, February 17-21, 2007. 64. McConnell KW, Muenzer JT, Chang KC, Coopersmith CM, Grigsby PW, Hotchkiss RS, Hunt CR. Peptide transduction domain delivery of anti-apoptotic proteins decreases splenocyte apoptosis in preand post-treatment models of murine radiation injury. Presented to the 36th Critical Care Congress, Society of Critical Care Medicine, Orlando, FL, February 17-21, 2007 (Research Citation Finalist). 65. Clark JA, Hotchkiss RS, Buchman TG, Coopersmith CM. The role of epidermal growth factor in rd sepsis. Presented to the 3 annual Washington University School of Medicine Postdoct Scientific Symposium. St. Louism MO March 1, 2007 (Best poster winner). 66. Clark AT, Woolsey CA, Dunne WM, Buchman TG, Hotchkiss RS, Coopersmith CM. Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal epithelial proliferation and slows migration. Presented to the 7th World Congress on Trauma, Shock, Inflammation and Sepsis - Interdisciplinary Summit on Inflammation Munich, Germany March 13-17, 2007 (A.E. Baue Research Award as one of top 5 abstracts). 67. Clark JA, Stromberg PE, Hotchkiss RS, Buchman TG, Coopersmith CM. Exogenous epidermal growth factor improves intestinal integrity in sepsis. Presented to the 7th World Congress on Trauma, Shock, Inflammation and Sepsis - Interdisciplinary Summit on Inflammation Munich, Germany March 1317, 2007. 68. Robertson CM, McConnell KW, Chang K, Houchen C, Hotchkiss RS, Coopersmith CM. Tat-BH4 Decreases Intestinal Epithelial Cell Death after Septic Insult in Vitro. Presented to the 7th World Congress on Trauma, Shock, Inflammation and Sepsis - Interdisciplinary Summit on Inflammation Munich, Germany March 13-17, 2007. 69. McConnell KW, McDunn JE, Turnbull IR, Dunne WM, Hotchkiss RS, Coopersmith CM. Gram positive and gram negative bacteria initiate the host inflammatory response via different mechanisms. Presented to the 7th World Congress on Trauma, Shock, Inflammation and Sepsis - Interdisciplinary Summit on Inflammation Munich, Germany March 13-17, 2007. 70. Rogers TJ, Dunne WM, Guth RM, Merz LR, Coopersmith CM, Scheurer DJE, Fraser VJ, Warren DK. Implications of a Chlorhexidine-based Washing Protocol on Methicillin-Resistant Staphylococcus aureus Tolerance to Chlorhexidine Digluconate. Presented to the 17th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America, Baltimore, MD, April 14-17, 2007. 71. Clark JA, Hotchkiss RS, Buchman TG, Coopersmith CM. Decreased mortality following epidermal th growth factor treatment is associated with improved gut inegrity in sepsis. Presented to the 30 annual conference on Shock, Shock Society, Baltimore, MD, June 9-12, 2007. (Young investigator award finalist) 72. Clark AT, Turnbull IR, Stromberg PE, Woolsey CA, Buchman TG, Hotchkiss RS, Coopersmith CM. Aging modulates local but not systemic inflammation following cecal ligation and puncture in mice. th Presented to the 30 annual conference on Shock, Shock Society, Baltimore, MD, June 9-12, 2007. 73. McConnell KW, Stromberg PE, Woolsey CA, Clark AT, Clark JA, Hotchkiss RS, Buchman TG, Coopersmith CM. The survival advantage conferred by prevention of gut epithelial apoptosis in sepsis occurs through the mitochondrial pathway and is dependent upon the presence of the adaptive immune th system. Presented to the 30 annual conference on Shock, Shock Society, Baltimore, MD, June 9-12, 2007. 74. Peck-Palmer OM, McConnell K, Unsinger J, Chang K, McDunn JE, Coopersmith CM, Hotchkiss RS. Monocyte/macrophage apoptosis occurs with radiation and serum-deprivation but not E. coli. Presented th to the 30 annual conference on Shock, Shock Society, Baltimore, MD, June 9-12, 2007. 75. Robertson CM, McConnell KW, Martin J, Boody B, Diavolo J, Dunne WM, Coopersmith CM. Neutrophil depletion inhibits pulmonary clearance of Staphylococcus aureus in mice. Presented to the th 30 annual conference on Shock, Shock Society, Baltimore, MD, June 9-12, 2007. 76. Clark JA, Samocha A, Hotchkiss RS, Buchman TG, Coopersmith CM. NF-kB activation in enterocytes reduces sepsis-induced gut inury. Presented to 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008. 77. Perrone EE, Clark JA, Hotchkiss RS, Buchman TG, Coopersmith CM. Loss of EGF receptor activity leads to increased intestinal apoptosis and decreased villus height in sepsis. Presented to 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008. 78. Robertson CM, Belt BA, Linehan DC, Buchman TG, Hotchkiss RS, Coopersmith CM. Novel models of murine sepsis with comorbid pancreatic cancer. Presented to 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008. 79. Clark AT, Turnbull IR, Stromberg PE, Woolsey CA, Buchman TG, Hotchkiss RS, Coopersmith CM. Age increases local but not systemic inflammation in murine sepsis. Presented to 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008. 80. Fox AC, Clark AT, Zee-Cheng B, Dunne WM, Buchman TG, Hotchkiss RS, Coopersmith CM. Sepsis from Pseudomonas aeruginosa pnemonia decreases epithelial proliferation and migration with partial recovery of regenerative capacity 48 hours post-inury. Presented to 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008. 81. Taylor BE, Byrnes M, Schallom M, Sona C, Quist M, Boyle WA, Buchman TG, Coopersmith CM, Tobin G. Implementation of a transition insulin protocol to maintain glycemic control after intensive insulin therapy. Presented to 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008. 82. Gnerlich J, Coopersmith CM, Fraser V, Schuerer DJE. Increasing patient safety in a SICU: staff concerns survey. Presented to 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008. 83. Byrnes ME, Sona CS, Schuerer DJE, Mazuski JE, McKenzie W, Taylor BE, Boyle WA, Coopersmith CM. Daily review of a checklist of ICU guidelines improves adherence to established ICU protocols and objectives. Presented to 37th Critical Care Congress, Society of Critical Care Medicine, Honolulu, HI February 1-6, 2008. 84. Robertson CM, Klingensmith ME, Coopersmith CM. National prevalence of full-time research experience among general surgery residents. Presented to Third Annual Academic Surgery Congress, Society of University Surgeons, Hungtington Beach, CA Feb 12-15, 2008. 85. Clark JA, Lawrance CP, Dunne WM, Coopersmith CM. Epidermal growth factor preserves intestinal integrity and decreases mortality in a murine model of Pseudomonas aeruginosa pneumonia. Presented to Experimenal Biology, San Diego, CA, April 5-9, 2008. 86. Perrone EE, Brahmamdan P, Davis CG, McDonough JS, Buchman TG, Hotchkiss RS, Coopersmith CM. Radiation injury increases systemic infection and mortality in murine MRSA pneumonia. Presented to to the 31st annual conference on Shock, Shock Society, Cologne, GE, June 28-July 2, 2008. 87. Clark AT, McConnell KW, Dunne WM, Dixon DJ, Cobb JP, Buchman TG, Hotchkiss RS, Coopersmith CM. Anti-TNF modulates mortality from S. pneumoniae and P. aeruginosa pneumonia in mice. Presented to to the 31st annual conference on Shock, Shock Society, Cologne, GE, June 28-July 2, 2008. 88. Fox A, Robertson C, Belt B, Dunne WM, Linehan D, Buchman T, Hotchkiss R, Coopersmith CM. Sepsis from Pseudomonas aeruginosa pnemonia superimposed on pancreatic cancer increases gut epithelial apoptosis, bacteremia, and mortality. Presented to to the 31st annual conference on Shock, Shock Society, Cologne, GE, June 28-July 2, 2008. (Travel awardee). 89. Clark JA, Hotchkiss Rs, Buchman TG, Coopersmith CM. Intestinal overexpression of epidermal growth factor inhibits gut epithelial apoptosis and improves mortality in sepsis. Presented to the 31st annual conference on Shock, Shock Society, Cologne, GE, June 28-July 2, 2008. 90. Perrone EE, Clark JA, Clark AT, Dunne WM, Warner BW, Coopersmith CM. Staphylococcus aureus induces intestinal injury in a murine model of pneumonia. Presented to the 2008 AAP National Conference and Exhibition, Section on Surgery, Boston, MA, October 10-14, 2008. 91. Brahmamdam P, Chang KC, Zeida RK, Rele SM, Liang Y, Liu JY, Heidel JD, McDunn JE, Coopersmith CM, Hotchkiss RS. siRNA targeted at pro-apoptotic proteins, PUMA and BIM, inhibits sepsis-induced lymphocyte apoptosis. Presented to the 94th annual clinical congress of the American College of Surgeons. San Francisco, CA October 12-16, 2008. 92. Clark J, Samocha A, Gan H, Coopersmith CM. Enterocyte-specific overexpression of epidermal growth factor preserves intestinal barrier function in sepsis. Presented to the 38th Critical Care Congress, Society of Critical Care Medicine, Nashville, TN January 31-February 4, 2009. 93. Jung E, Perrone EE, Brahmandan P, Davis CG, McDonough JS, Clark JA, Clark AT, Fox AC, Dunne WM, Buchman TG, Hotchkiss RS, Coopersmith CM. Intestional overexpression of Bcl-2 decrease gut epithelial apoptosis and improves survival in mice subjected to whole body irradiation followed by MRSA pneumonia. Presented to the 38th Critical Care Congress, Society of Critical Care Medicine, Nashville, TN January 31-February 4, 2009. 94. Clark AT, Hotckiss WR, Zee-Cheng BR, Clark JA, Fox AC, McConnell KW, Dunne WM, Buchman TG, Coopersmith CM. Site and source of infection mediate local and systemic host response in septic mice. Presented to the 38th Critical Care Congress, Society of Critical Care Medicine, Nashville, TN January 31-February 4, 2009. 95. Fox AC, Clark AT, Chang K, Dunne WM, Linehan D, Coopersmith CM. Preventing apoptosis in septic mice with cancer unexpectedly increases mortality. Presented to the 38th Critical Care Congress, Society of Critical Care Medicine, Nashville, TN January 31-February 4, 2009. 96. Schuerer DJE, Buchman TG, Coopersmith CM. Catheter-related bloodstream infection rates in minocycline/rifampin vs. chlorhexidine/silver sulfadiazine-impregnated central venous catheters -- results of a 46 month study Presented to the 38th Critical Care Congress, Society of Critical Care Medicine, Nashville, TN January 31-February 4, 2009. 97. Brahmamdam, Coopersmith CM, Chang KC, Osborne DF, McDunn JE, Hotchkiss RS. Blocking PD1 inhibits lymphocyte apoptosis during sepsis. Presented to the 38th Critical Care Congress, Society of Critical Care Medicine, Nashville, TN January 31-February 4, 2009. 97. Fox AC, McConnell KW, Clark AT, Dunne WM, Buchman TG, Hotchkiss RS, Coopersmith CM. Endogenous bacteria decreae mortality in sepsis but do not change intestinal epithelial apoptosis or proliferation. Presented to the 4th Annual Academic Surgical Congress, Fort Myers FL, February 3-6, 2009. 98. Clark JA, Xie Y, Coopersmith CM, Davidson NO. Impaired intestinal lipid metabolism decreases mortality and improves intestinal integrity in Pseudomonas aeruginosa pneumonia-induced sepsis. Presented to Digestive Disease Weeks, Chicago, IL, June 3, 2009. 99. Clark A, Zee-Cheng B, Dunne WM, Buchman TG, Hotchkiss RS, Coopersmith CM. Sepsis uncouples gut epithelial proliferation and death from migration and cell density in mice. Accepted for presentation to the 32 nd annual conference on Shock, Shock Society, San Antonio, TX, June 6-9, 2009. 100. Clark J, Samocha A, Coopersmith CM. Anti-TNF prevents gut barrier dysfunction in septic mice. Accepted for presentation to the 32 nd annual conference on Shock, Shock Society, San Antonio, TX, June 6-9, 2009. 101. Jung E, Perron E, Clark J, Clark A, Dunne W, Buchman T, Hotchkiss R, Coopersmith CM. Mechanisms of MRSA pneumonia-induced gut epithelial apoptosis. Accepted for presentation to the 32 nd annual conference on Shock, Shock Society, San Antonio, TX, June 6-9, 2009 (Travel awardee). 102. Fox A, McConnell K, Clark A, Dunne W, Coopersmith CM. The endogenous bacteria mediate sepsis-induced increases in gut epithelial apoptosis. Accepted for presentation to the 32 nd annual conference on Shock, Shock Society, San Antonio, TX, June 6-9, 2009 (Travel awardee). 103. Inoue S, Davis CG, Muenzer JT, Coopersmith CM, Hotchkiss RS. The development of a clinically relevant two-hit model of sepsis: Streptoccocus pneumoniae followed by Pseudomonas pneumonia. Presented to the 39th Critical Care Congress, Society of Critical Care Medicine, Miami, FL January January 10-13, 2010. 104. Dominguez J, Vithayathil P, Lawrance C, Coopersmith CM. Epidermal growth factor attenuates gut injury and decreases mortality in Pseudomonas aeruginosa pneumonia-induced sepsis. Presented to the rd 33 annual conference on Shock, Shock Society, Portland, OR, June 11-15, 2010 (Plenary abstract, travel awardee). 105. Jung E, Perrone E, Brahmamdan, McDonough J, Davis C, Dominguez J, Hotchkiss R, Coopersmith CM. Mechanisms through which gut Bcl-2 overexpression improves survival in mice given irradiation rd followed by MRSA pneumonia. Presented to the 33 annual conference on Shock, Shock Society, Portland, OR, June 11-15, 2010 (Travel awardee). 106. Ingram T, Kamat P, Coopersmith C, Vats A. Impact of family presence during rounds on physician comfort and perception of teaching and efficiency. Presented to the 40th Critical Care Congress, Society of Critical Care Medicine, San Diego, CA January 15-18, 2011 (Patient and Family Specialty Award). 107. Dominguez J, Khailova L, Vithayathil P, Lawrance C, Coopersmith C. Decreased mortality following epidermal growth factor treatment is associated with attenuated intestinal injury in Pseudomonas aeruginosa pneumonia. . Presented to the 40th Critical Care Congress, Society of Critical Care Medicine, San Diego, CA January 15-18, 2011 108. Liang Z, Breed ER, Dominguez JA, Coopersmith CM. The role of epidermal growth factor in th mediating age-dependent mortality in sepsis. Presented to the 34 annual conference on Shock, Shock Society, Norfolk, VA, June 11-14, 2011. 109. Liang Z, Breed ER, Buchman TG, Coopersmith CM. Heavy water (D2O) sensitized mice to cecal th ligation and puncture (CLP). Presented to the 34 annual conference on Shock, Shock Society, Norfolk, VA, June 11-14, 2011. 110. Breed ER, Jung E, Liang Z, Perone EE, Dominguez JA, Dunne WM, Burd EM, Buchman TG, Coopersmith CM. Methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa pneumonia th induce inestinal epithelial apoptosis via distinct mechanisms. Presented to the 34 annual conference on Shock, Shock Society, Norfolk, VA, June 11-14, 2011. 111. Perrone EE, Jung E, Dominguez JA, Clark AT, Fox AC, Dunne WM, Hotchkiss RS, Coopersmith CM. Cecal ligation and puncture followed by MRSA pneumonia increases mortality in mice and blunts th production of local and systemic cytokines. Presented to the 97 Annual Clinical Congress, American College of Surgeons, San Francisco, CA, October 2011. 112. Carpenter D, Gregg S, Owens D, Buchman TG, Coopersmith CM. Documentation of Patient Care Time by Nurse Practitioners and Physician Assistants in the Intensive Care Unit Accepted for st presentation to the 41 Critical Care Congress, Society of Critical Care Medicine, Houston, TX , Feb 4-8, 2012. 113. Still M, Cross L, Carpenter D, Coopersmith CM. The turn team: a novel strategy for reducing unit st acquired pressure ulcers in the ICU. Accepted for presentation to the 41 Critical Care Congress, Society of Critical Care Medicine, Houston, TX , Feb 4-8, 2012. 114. Yoseph B, Breed E, Liang Z, Fox AC, McConnell K, O’Donnell D, Dunne WM, Coopersmith CM. Commensal bacteria play a protective role in mediating mortality from pneumonia-induced sepsis. rd Accepted for presentation to the 33 annual meeting of the Surgical Infection Society. Dallas, TX April 1821, 2012. 115. Yoseph B, Breed E, Liang Z, Dominguez JA, McConnell, Coopersmith CM. Sepsis increses th intestinal permeability by altering the tight junction. Accepted for presention to the 35 annual conference on Shock, Shock Society, Miami, FL, June 10-13, 2012. (Travel awardee). 116. Breed ER, Liang Z, Wagener ME, Yoseph B, Ferrer IR, Ford ML, Buchman TG, Coopersmith CM. th Heavy water mitigates survival in septic mice. Accepted for presention to the 35 annual conference on Shock, Shock Society, Miami, FL, June 10-13, 2012. 117. Liang Z, Xie Y, Dominguez JA, Breed ER, Yoseph B, Davidson NO, Coopersmith CM. Intestinespecific Mttp deletion increases mortality in an aged murine model of Pseudomonas aeruginosa th pneumonia. Accepted for presention to the 35 annual conference on Shock, Shock Society, Miami, FL, June 10-13, 2012. (Travel awardee). 118. Jaffree LS, Liang Z, Breed E, Coopersmith CM. The protective effect of epdiermal growth factor th during sepsis depends on the adaptive immune system. Accepted for presention to the 35 annual conference on Shock, Shock Society, Miami, FL, June 10-13, 2012. (Travel awardee). Trainees (laboratory): 2000-2004 Paul Stromberg -- Accepted to Vanderbilt School of Medicine (started 8/04) 2002-2004 Keary Husain, MD – Assistant Professor of Surgery, Washington University School of Medicine 2002-2004 Pardis Javadi – ENT resident, Albany Medical Center 2002-2006 Cheryl Woolsey, BS –Physicians Assistant, Washington University 2003,2007 Isaiah Turnbull, PhD – Received PhD at Washington University after Masters training, Now an general surgery resident at the same institution 2003-2005 Dinesh Vyas, MBBS – Accepted to PGY2 preliminary general surgical position University of Pittsburgh (started 8/05) then to PGY4 categorical general surgical position Case Western Reserve, Now an assistant professor of surgery Michigan State University 2004-2007 Kevin McConnell, MD – Assistant Professor of Surgery, Emory University School of Medicine, Recipient of NIH Loan Repayment Program Grant 2004-2007 2005-2007 Charles Robertson, MD – Assistant Professor of Anesthesiology, Washington University School of Medicine 2005-2006 Saju Rajan – MA/MD student (obtained master’s degree following second year of medical school at Washington University School of Medicine), now Radiation Oncology resident Roswell Park Recipient of NIH NIDDK Medical Student Training Application 20052006. 2005, 2006 James Martin (summer college student) – ENT resident, Loyola School of Medicine 2005, 2006 Barrett Boody (summer college student) – Accepted to University of Chicago School of Medicine (started 9/08) 2005 Ben Sherman (summer college student) – Accepted to Arizona State for PhD program in biochemistry (started 9/08) 2006 William Osberghaus (summer college student) 2006-2009 Jessica Clark, PhD – Assistant Professor of Anesthesiology, Colorado University. Recipient of NIH National Research Service Award, Shock Society Young Investigator Award. 2007 Christopher Lawrance –General Surgery resident, Washington University School of Medicine, Recipient of SIU Mentored Professional Enrichment Experience Scholarship. 2007,8,9 Brendan Zee Chang (summer college student) 2007,8,9 Alexandr Samocha (outreach high school student) –University of Pennsylvania (started 9/08) 2007-2009 Amy Fox, MD -- Endocrine Surgery Fellow, University of Michigan 2007-2008 Erin Perrone, MD – Surgery Resident, Wayne State 2008-2009 Heng Gan (Washington University undergraduate student) – Accepted to Temple University School of Medicine (starts 9/09) Recipient of Washington University Department of Biology Summer Undegraduate Research Fellowship Award, also graduated with honors thesis in biology from Washington University. 2008 Jada Roe – Medical student Washington University School of Medicine (summer after first year of medical school). Recipient of NIH NIDDK Short-term Training Grant for Medical Students. 2008-2009 Enjae Jung, MD – Vascular Surgery fellow, Washington University School of Medicine 2009 Paul Vithayathil (Washington University undergraduate student) 2010-present Elise Breed 2011-2012 Layla Jaffree (discover phase student, Emory University School of Medicine 2011-present Benyam Yoseph, MD – Postdoctoral fellow, Emory University School of Medicine Trainees (clinical) 2002-2003 Aaron Sciifres – Assistant Professor of Surgery, St. Louis University 2002-2003 Joseph Rodriguez – Trauma Fellowship Cook County Hospital 2003-2004 Charles Hu – Assistant Professor of Surgery, Loma Linda University, SICU Director Riverside County Regional Medical Center 2004-2005 Michael Edwards – Minimally invasive surgery fellowship, Harvard University, Assistant Professor of Surgery Medical College of Georgia 2004-2005 Patricia Penkoske – Instructor, Washington University School of Medicine 2005-2006 Ellen Omi – Assistant Professor of Surgery, Loyola University 2005-2006 Pamela Peigh, private practice St. Louis, MO 2006-2007 Matthew Byrnes -- Assistant professor of surgery University of Minnesota 2007-2008 Matthew Goede –Assistant professor of surgery, University of Nebraska 2007-2008 Phil Efron – Assistant professor of surgery University of Florida 2008-2009 Robert Southard – Assistant professor of surgery, Washington University 2008-2009 Sean Nix—Assistant professor of surgery, University of Oklahoma Mentees (other) 2008-2009 Chris Carpenter (Assistant Professor of Emergency Medicine, Washington University) Recipient of Goldfarb Patient Safety Fellowship Personal: 1983-present Songwriter/guitarist. Have written or co-written approximately 100 songs. Recently recorded compact disc of original music. Have received college radio airplay, commissioned to write and record themes for two cable television shows. 1983-1987 Editorial page editor, reporter The Daily Pennsylvanian. Over 250 publications including multiple stories reported by the Associated Press. Named top college newspaper in nation.
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