INFLUENCE OF YELLOW FILTER ON CONTRAST SENSITIVITY FOR FREQUENCY DOUBLING TECHNOLOGY PERIMETRY PÉREZ M J1, SÁNCHEZ C1, PUELL C1, LANGA A1 INTRODUCTION Nowadays, yellow filters are used because of the apparent improvement on brightness perception (Chung et al., 1999; Kelly, 1990) as well as on the contrast sensitivity under photopic illumination conditions (Yap, 1984; Rabin et al., 1996; Wolffsohn et al., 2000), and also on several ocular pathologies (Rosenblum et al., 2000; Linnik et al., 1992, Kinney et al. 1983ª). However, under mesopic conditions the existent studies are scarce and that of Yap (1984) does not find any improvements either. The purpose of this investigation was to determine the effect of the yellow filter X-482, with coated treatment, on photopic contrast sensitivity (CS) for frequency doubling tchnology (FDT) perimetry in the central visual field (20º); with the intention of psychophysically quantifying its influence on the visual performance. METHOD The sample studied consisted of 28 adult subjects :22 women (78%) and 6 men (22%) with an average age of 38.39 years (max= 55 years; min= 21 years). They were all emmetropic ( 0,5 D), had at least 6/6 Snellen visual acuity and absence of ocular pathologies and pharmacological treatments. The contrast threshold was measured in the right eye of the subjects. The environmental photopic illumination was of 20 0,3 cd/m2. The measures of luminance were obtained with the IL1400A 3448 photometer, calibrated to measure illumination levels in cd/m2, in combination with the detector SPLO25Y 238. The selected protocol to carry out the psychophysics measures with the interference of yellow and neutral filters was the following: A 5-minute period of adaptation to the illumination conditions, during which the process for the tests was explained. Then we determined contrast thresholds. Measures were carried out with neutral filter first on half of the subjects and with yellow filter first on the other half, so as to avoid the learning effect. The cut-off filter selected was the Essilor X-482 (yellow residual colour), with a transmittance of 0,503 for 482 nm. and transmittance-matched neutral filter (ND), both with a luminous transmittance of 0.71. The filters were subject to a multi-layer coated treatment with a residual reflection of 0,4%. Figure 1 shows the X-482 spectral transmittance curve obtained with the UV-SENSE Recording Spectrophotometer UV-2401 PC of Shimadizu Corporation Company of Japan. The filters were incorporated to a spectacle frame adapted to the subjects or were worn over the subject’s best spectacle correction. Dept. Optics. Optic and Optometry School. UCM (Spain) Frequency Doubling Technology is based on the premise that the low spatial frequency in combination with the high temporal frequency of the stimulus will preferentially stimulate Magnocellular (M- cell) mechanisms,which are believed to be primarily involved in the detection of motion and rapid flicker or luminance change (Johnson et al.,1999; Adams et al.,1999)). The frequency doubling percept is produced by a non-linear response to contrast, M-cells exhibiting nonlinear responses to stimulus contrast represent a small portion (aproximately 25%) of the total number of M-cells. It is this non-linear response to contras that is believed to produce the frecuency doubling appearance. When a low spatial frequency sinusoidal grating undergoes high temporal frequency counterphase flicker, the stimulus display appears to have twice as many light and dark bars than are actually physically present (Figure 3). Contrast sensitivity was determined at each location by means of a modified binary search (MOBS) staircase procedure EVER 2002, Alicante Total sample differences among the contrast sensitivity with the X-482 filter and ND filter gave significant differences for the periphery area ( p= 0,0140). Figure 5 shows the differences between men and women for the periphery area. Only the women’s group gave significant differences (p= 0,0067). 29,6 CS (dD) Figure 5. Differences among the men and women contrast sensitivity results with ND filter and the yellow filter for the periphery area. 29,2 ND Filter X- 482 Filter 28,8 28,4 MEN WOMEN Table 1. Contrast sensitivity values obtained in younger and elder groups p-value= TOTAL Figure 2. The Humphrey Systems FDT Perimeter The task did not take more than 5,1 minutes on each subject’s eye. The influence of the filter on the different variables studied was analysed by means of Student’s "t" for paired data.( Statgraphics 5.0) Figure 1. Transmittance curve of the filter X-482. FOVEA PERIPHERY ND X-482 ND X-482 ND X-482 Younger 29.7 3.6 29.4 2.5 31.7 10 29.0 3.7 29.2 2.4 29.5 2.6 p-value= 0.59 p-value= 0.38 p-value= 0.30 Elder 28.7 3.2 29.0 3.1 29.0 4.5 28.5 3.4 28.6 3.1 29.1 3.3 p-value= 0.28 p-value= 0.49 * p-value= 0.04 Figure 3. Frequency doubling of the stimulus RESULTS. Figure 4 shows the contrast sensitivity mean obtained with yellow filter and ND filter in the established areas of the visual field (20º). The results obtained with the yellow filter showed a increase of the CS in the periphery area (29.39 3.241dB). However, no statistical significance was found in the 5º central area (29.10 3.47dB). In the four quadrants, the CS values were higher than those obtained with ND filter but without statistical significance. Sample was divided in two age groups: Younger ( 35 years) and elder ( 36 years). Last group ( 36 years) CS had significant differences (p= 0.04) in the periphery area of the visual field (20º). Rest of studied areas for the two groups, the contrast sensitivity measures didn’t give statistical significance between the yellow filter and neutral filter (Table 1). CONCLUSION Photopic contrast sensitivity for frequency doubling tchnology (FDT) improved through the coated yellow filter for the periphery area of the visual field (20º). Therefore, the effect of yellow filter without residual reflections had a positive influence on the contrast perception of healthy subjects at low spatial frequency. 30,4 ACKNOWLEDGMENT. The yellow filters used were kindly supplied by Essilor España, S.A. CS (dB) 30 REFERENCES . Adams CW., Bullimore MA., Wall M, Fingeret M, Johnson CA. Normal aging effects for Frequency Doubling Technology Perimetry. Optom Vis Sci. 1999; 76-8: 582-587. . Chung S., Pease, P. L. 1999. Effect of yellow filters in pupil size. Optom. Vis. 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