No1, 2017
US $8 / EU €6 / GB £5
The in-house magazine for the IAS Private Members Club
THE CLASS
LEADERS
In this issue:
The
anti-cataract
eye-drop
How to get your
omegas from
plant oils
The wrinkle
remover
Peptide
bioregulator
gene-switches
AGINGMATTERS
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TOMORROW’S TREATMENTS TODAY™
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you access the world’s
latest commercially available
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and formulas give you the best
possible results.
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you. We can be bothered!
2
AGINGMATTERS
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Declaration: The IAS Aging Matters™ magazine
is intended for IAS private club members (and
therefore is not intended for the public). It
focuses on the latest international nutritional,
hormonal and drug therapies to help combat
the signs of aging. These signs include the
physical, mental and internal changes consisting
of the diseases and disorders such as cancer,
arthritis and senile dementias etc. However,
the main focus is upon the prevention of s
uch aging diseases and disorders for the
healthy-aging’ individual.
Copyright 2017: All copyrights are acknowledged.
Whilst every effort has been made to ensure
accuracy, no responsibility can be accepted for
illustrations, photographs, artwork or advertising
materials while in transmission or with the
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Disclaimer: All educational information
is offered under IAS terms and conditions.
This information does not replace the advice
of your physician and restrictions may apply in
some countries. The opinions expressed by the
writers may not be those of IAS or the magazine.
All prices shown are in US Dollars and are for
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terms are subject to change without notice.
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CONTENTS
CONTENTS
03
22
53
Welcome
Why plants are
better than fish
for omegas
A-Z product
listing and prices
How PEOs deliver the
right balance
57
30
Testimonials &
Explanations
A Happy New Year
04
Forefront
Interesting items in the news
04
Can teeth really repair themselves naturally?
06
Heart of the matter
08
Research suggests the
appendix has a purpose
after all
10
The aging brain
16
Reversing and
preventing
cataracts
it’s been known for more
than 15-years!
The proven topical wrinkle
remover
Tretinoin cream remains
unbeaten
38
Peptide
bioregulators
are gene switches
Why is this so important?
48
Find everything in-stock here
Nice comments from
nice people
58
Contact details
& payment
options
Get in touch with IAS today
60
March 2017
price list
Cross-reference
lists
FEATURED
PRODUCTS
12
Centrophenoxine
13
Deprenyl
14
Piracetam
15
MZS Melatonin
36
Esnatri
37
Thyroid Support
44
Youth Gems
45
GHRPs
46
Oxytocin
47
BioClip® Cuff
Find what you need here
WELCOME
It’s 2017 and we trust that this New Year brings you and your
family happiness, prosperity and above all- health.
Obviously, without good health we can’t help ourselves or
others. That’s why; we thought that we’d start the year with a
reminder of some of the class leading remedies. For example;
how to rescue and improve aging eyesight; plus how to ensure
good arterial and heart health; how to remove and reduce the
appearance of wrinkles and also why the discovery of peptide
bioregulators to act as gene-switches is so important. We hope
there is something here for you.
Please note that there will be some changes to the
Aging Matters™ magazine.
Fundamentally, there will be 4 issues per year rather than
the previous 6, but each issue will be bigger than before and
they will have a broader range of topics, including articles,
interviews, book reviews and other interesting subjects that
are current and hot.
So we hope you will join us as we enter 2017 with
a renewed vigor and zest for life and health.
Phil Micans, MS, PharmB
Editor, Aging Matters™ Magazine
Ward Dean, M.D.
Medical Director
AGINGMATTERS
3
FOREFRONT
CAN TEETH REALLY
REPAIR THEMSELVES
NATURALLY?
A new approach to dentistry could be a game changer for
dentists and herald the end of numb mouths and painful
drilling. A simple no pain approach banishing man made
cements which are prone to infection and often need
replacing a number of times.
Scientists have discovered that a drug already trialled in
Alzheimer’s patients can encourage tooth regrowth and
repair cavities. In the future dentists could just regrow
your teeth, putting an end to fillings!
This discovery came from researchers at King's College
London. The team found that the drug Tideglusib stimulates
the stem cells contained in the pulp of teeth so that they
generate new dentine – the mineralised material under the
enamel. We already know that teeth have the capability of
regenerating dentine if the pulp inside the tooth becomes
exposed through a trauma or infection, but can only naturally
make a very thin layer which isn’t enough to fill the deep
cavities caused by tooth decay.
The drug Tideglusib switches off an enzyme called GSK-3
which prevents dentine to keep forming. Scientists revealed
it is possible to soak a small biodegradable sponge with the
drug and insert it into a cavity, where it triggers the growth
of dentine and repairs the damage within six weeks. The tiny
sponges are made out of collagen so they melt away, leaving
only the repaired tooth.
The lead author of the study, Professor Paul Sharpe of the
Dental Institute, from King’s College London, said: “The
simplicity of our approach makes it ideal as a clinical dental
product for the natural treatment of large cavities, by providing
both pulp protection and restoring dentine. He also said: “In
addition, using a drug that has already been tested in clinical
trials for Alzheimer’s disease provides a real opportunity to get
this dental treatment quickly into clinics.”
Dentists currently use man-made cements or fillings, such as
calcium and silicon-based products, to treat larger cavities and
4
AGINGMATTERS
fill holes in teeth. But, the cement remains in the tooth and
fails to disintegrate, meaning that the normal mineral level of
the tooth is never completely restored. The new technique
could reduce the need for fillings of cements, which are prone
to infection and often need replacing a number of times. When
fillings fail or infection occurs, dentists have to remove and fill
an area that is larger than what is affected, and after multiple
treatments the tooth may eventually need to be taken out.
Dr Nigel Carter, CEO of the Oral Health Foundation
commented on the discovery: “This is an extremely interesting
and novel approach which shows great promise and we will
look forward to it being translated into clinical application that
could undoubtedly be a progressive step in the treatment of
dental disease.” He added: “While fillings have remained highly
effective in repairing large cavities, they are susceptible to
wear-and-tear and can occasionally be in need of repair and
replacement. This presents problems as the dentist could have
to remove and fill a larger area each time and after numerous
treatments the tooth may then have to be extracted.”
He concluded: “Creating a more natural way for the tooth to
repair itself could not only eliminate these issues, but also
be a far less invasive treatment option for patients. With
dental phobia still being very common, using a natural way
to stimulate the renewal of dentine could be an especially
comforting proposal for these groups, for which undergoing
treatment can often be a cause great anxiety.”
Whilst this is a ground breaking discovery, the procedure has
so far only been used in mouse teeth, but it was shown to 'fill
the whole injury site'.
As to when patients might start seeing Tideglusib at their local
dentist, it will likely be at least a few more years. The American
Dental Association (ADA) has indicated that it’s “too soon” to
know whether or not the procedure has any viable clinical
application. But if the drug is truly safe and works in animals,
it will likely have similar benefits in humans.
The drug Tideglusib has already been shown to be safe in
clinical trials of patients with Alzheimer's disease so scientists
say that the treatment could be fast-tracked into dental
practices.
Treating cavities with standard dental fillings may soon be
a distant memory because of a new era of regenerative
medicine. We now have the restorative tools needed to
consign fillings to history.
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
FOREFRONT
The tooth regenerates by forming a layer
of hard dentine over cavities potentially
repairing themselves naturally.
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
AGINGMATTERS
5
FOREFRONT
HEART OF
THE MATTER
Cholesterol-lowering statin drugs
increase progression of coronary
artery calcification
Statins are a class of lipid-lowering medications normally
associated with cardiovascular disease. They are considered
one of the most profitable medications produced by the Big
Pharma's. The National Center for Health Statistics claims that
50% of men age 65-74, and 40% of women over the age of
75 take a statin medication. It was reported that 32 million
Americans were taking a statin drug in a study in 2011.
The statin drug study has shown that cholesterol lowering
statins increase the progression of coronary artery
calcification. In most cases, cardiologists order coronary artery
calcium scores to assess how much calcium is deposited
in the coronary arteries. The higher the coronary artery
calcium score, the more risk there is for having a heart attack.
According to the Cleveland Clinic, “Coronary calcium scores
are the most sensitive approaches to detecting coronary
calcification from atherosclerosis before symptoms develop.”
The team of researchers studied eight prospective randomized
trials using coronary intravascular ultrasound looking for serial
changes in the calcium burden in the coronary arteries. The
authors grouped the subjects into three groups; those treated
with high-intensity statin therapy, low-intensity statin therapy,
and no-statin therapy. The scientists found that all three
groups were found to have significant increases in coronary
calcium scores when the groups were compared to baseline.
The high-intensity group had the largest calcium increase and
the low-intensity statin group was next in line followed by the
no-statin group.
Physicians have been testing untold numbers of patients for
their coronary calcium score. When the score is too high,
they are told that they are at an increased risk for a cardiac
event. The patients are then prescribed statin medications
and frequently told to undergo further testing to evaluate the
coronary arteries.
6
AGINGMATTERS
An article in The Journal of the American College of Cardiology
investigated whether the use of stains influences the
progression of coronary artery calcification during five years
of follow-up in subjects who took a statin medication and
compared them to subjects who did not take a statin drug.
The scientists reported that subjects who took statins for five
years, when compared to those that took a placebo, were
found to have an alarming 2-fold increase in coronary artery
calcification progression.
A board-certified family physician and Medical Director of
the Center of Holistic Medicine in West Bloomfield. Dr David
Brownststein has written a book called 'The Satin Disaster'.
He believes that Statins worsen the calcification of the
coronary arteries and he believes that statin drugs are a
colossal failure. At their best, they work to lower the risk of
a heart attack in approximately 1%. He says that there is no
justification for the mass prescribing of a class of medications
that fail nearly all who take them. Furthermore, it is important
to keep in mind that statins are not benign drugs as they are
associated with a host of serious side effects including muscle
aches and pains, neuropathy, and cancer.
Dr. Brownstein further says: “Statins are the perfect example
of a class of medications that is bankrupting our medical
system: As the new administration takes charge in Washington,
D.C., I hope someone will look at our medical care and make
rational decisions about which drugs should be used and
which should not.
”He added: “In the case of statin medications, a rational mind
would conclude that this class of medications should be pulled
from the market place. More information about statins can be
found in my book, The Statin Disaster.”
www.drbrownstein.com/The-Statin-Disaster-p/
statindisaster.htm
It is also recommended to watch these important
documentaries produced by medical doctors on statin drug.
The cholesterol drug war, part 1:
https://www.youtube.com/watch?v=sGIGXfIDaJo
The cholesterol drug war, part 2:
https://www.youtube.com/watch?v=AY4eTGMe-EY
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
FOREFRONT
A class of expensive medications that fail
most who take them and are associated
with serious side effects, is Bankrupting
our medical system.
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
AGINGMATTERS
7
FOREFRONT
RESEARCH SUGGESTS
THE APPENDIX HAS A
PURPOSE AFTER ALL
The appendix has long been a bit of a mystery. A worm-like
strip that projects off at the crossroads of the small and large
intestines, called the cecum. Conventional wisdom states that
the human appendix is the shrunken remnant of an organ that
once played an important role in a remote ancestor of humans
millions of years ago. The reason it still exists and occasionally
has to be removed due to potentially fatal inflammation and
rupturing – is that it is too evolutionary expensive to get rid of
altogether. There’s little evolutionary pressure to lose such a
significant part of the body.
However, it’s commonly considered a useless evolutionary
throwback whose sole purpose is to give you a nasty case of
appendicitis. Although, for the majority of people - it just sits
there not hurting anyone.
The human body has a number of 'vestigial' parts - appendix,
wisdom teeth and tailbone - that gradually fell out of use as
we adapted to more advanced lifestyles than our primitive
ancestors.
A new study out says our appendix could actually serve an
important biological function - and one that humans aren’t
ready to give up.
Researchers from Midwestern University in the USA traced
the appearance, disappearance, and re-emergence of the
appendix in several mammal lineages over the past 11 million
years, to work out how many times it was cut and brought back
due to evolutionary pressures.
The team found that the organ has evolved at least 29 times
– maybe, as many as 41 times - throughout mammalian
evolution, and has only been lost a maximum of 12 times.
"This statistically strong evidence that the appearance of the
appendix is significantly more probable than its loss suggests
a selective value for this structure," they reported.
8
AGINGMATTERS
"Thus, we can confidently reject the hypothesis that the
appendix is a vestigial structure with little adaptive value or
function among mammals."
To understand more, read the Comptes Rendus Palevol
articles. Devoted to palaeontology, pre-history and
evolutionary sciences. For decades, researchers have been
searching for a possible function of the human appendix, and
the most likely theory is that it’s a haven for 'good' intestinal
bacteria that help us keep certain infections at bay.
One of the best pieces of evidence they’ve had for this
suggestion is a 2012 study by Bill Parker, which found that
individuals without an appendix were four times more
likely to have a recurrence of Clostridium difficile colitis a bacterial infection that causes diarrhoea, fever, nausea,
and abdominal pain.
Researchers discovered that species that had retained or
regained an appendix had higher average concentrations
of lymphoid (immune) tissue in the cecum - a small pouch
connected to the junction of the small and large intestines.
Their findings suggest that the appendix could play an
important role in a species' immune system, particularly as
lymphatic tissue is known to stimulate the growth of certain
types of beneficial gut bacteria.
"While these links between the appendix and cecal factors
have been suggested before, this is the first time they have
been statistically validated,"
"The association between appendix presence and lymphoid
tissue provides support for the immune hypothesis of
appendix evolution."
The study is yet to be conclusive, but offers a different
perspective on the hypothesis that humans have been keeping
the appendix around for its immune support this whole time.
The challenge now is to prove it, which is easier said than done,
seeing as most people who have had their appendix removed
don't suffer from any adverse long-term effects.
But it could be that when people get their appendix removed,
immune cell-producing tissues in the cecum and elsewhere
in the body step up to compensate for the loss. In conclusion,
something that most people regard as a functionless body part
may save your life. Your appendix may help you recover from
serious infections.
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
FOREFRONT
Our appendix could actually serve an
important biological function - and one
that humans aren’t ready to give up.
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
AGINGMATTERS
9
FOREFRONT
THE AGING
BRAIN
Glia, not neurons, are most affected
by brain aging
As we age, deterioration of the brain sneaks up on most of
us. The first clue might be hearing loss. We may be forced
into bifocals, even trifocals. Our reflexes slow down, we walk
and act slower and we even talk slower. Our memory starts
to fail, especially the short-term form of memory ability that is
so crucial for learning new things. When brain cells die or are
damaged for any reason, healthy neurons are assaulted by
inflammatory chemicals, like cytokines, that are released by
the brain’s immune cell system. Brain inflammation is
commonly caused by infections such as colds and flu and
by diets deficient in anti-oxidants.
The brain is home to two kinds of cells – neurons and glia,
with the latter protecting the former. The difference between
a young brain and an old brain isn't so much the number of
neurons but the presence and function of supporting cells
called glia.
In Cell Reports on January 10, researchers who examined
postmortem brain samples from 480 individuals ranging in
age from 16 to 106 found that the condition of someone's glia
is so consistent through the years that it can be used to predict
someone's age. The research lays the foundation to better
understand glia's role in late-in-life brain disease.
Jernej Ule, a neurobiologist at the Francis Crick Institute
and the University College London, who led the study with
departmental colleague Rickie Patani (@PataniLab) and first
author Lilach Soreq reported: "We extensively characterized
aging-altered gene expression changes across 10 human
brain regions and found that, in fact, glia cells experience
bigger changes than neurons." Jerney added: "There's quite a
bit of regional information that will be of interest to different
people - for example some will notice a very unique pattern
of astrocyte-specific changes in the substantia nigra - and we
provide a lot of data that still needs to be analyzed."
10
AGINGMATTERS
There are three types of glia cells, each providing different
kinds of support to neurons: oligodendrocytes insulate,
microglia act as immune cells, and astrocytes help with neuron
metabolism, detoxification, among many functions. Based on
analysis of human brain tissue samples, primarily from the UK
Brain Expression Consortium, the team of researchers show
that astrocytes and oligodendrocytes shift their regional gene
expression patterns upon aging, (e.g., which genes are turned
on or off) particularly in the hippocampus and substantia
nigra - important brain regions for memory and movement,
respectively - while the expression of microglia-specific genes
increases in all brain regions.
Following on from that, the investigators took a preliminary
look at whether these changes in gene expression could relate
to changes in brain cell populations. Based on a comparison
of tissue samples from 3 young and 3 old brains, they found
that the number of oligodendrocytes decreases with age
in the frontal cortex. The researchers further established
that this likely corresponds with decreased expression of
oligodendrocyte specific genes. Other types of cells had
more complex patterns of change.
"We developed a very nice machine learning program and had
to go through hundreds of thousands of oligodendrocytes
and neurons to get reliable data, but we wanted to understand
whether decreased expression causes changes at the molecular
or cellular-level," Jernej Ule says: "We did see oligodendrocytes
disappearing but with neurons we didn't see dramatic changes
in cellular numbers except fora decrease in the largest neurons.
This is of interest because those largest neurons are generally
connected to neurodegenerative diseases."
One unexpected discovery was that certain glia gene expression
patterns could predict age in the general population. While this
can only be done postmortem, and certain people will not fit
neatly into these patterns, it does provide scientists one more
tool to understand how aging in the brain may be linked to
the causes of age-related disorders. The team of researchers'
ultimate goal is to see whether gene mutations or other
variables could affect gene expression in ways that
cause disease.
Materials for this article were provided by Cell Press. Cell Press
is a leading publisher of cutting-edge biomedical research
and reviews. They drive science forward and promote crosspollination of ideas with our passion for excellence and
commitment to innovation.
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FOREFRONT
Certain glia gene expression patterns could
predict age in the general population.
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
AGINGMATTERS
11
SPOTLIGHT
CENTROPHENOXINE
CENTROPHENOXINE,
(PRONOUNCED, CENT,
ROW-FEN, OX-IN) IS A
CLASSIC ‘SMART DRUG’
The term ‘smart drugs’ has become
synonymous with substances that
aid memory and cognition although
the correct medical terminology is
‘nootropics’ (which when translated
from Greek is – ‘towards the mind’).
Centrophenoxine is an ester of PCPA (a
plant compound) and DMA which is a
natural choline-based substance found
in the diet.
About Centrophenoxine
Centrophenoxine has been studied over
decades. Principally in Europe and one
of its leading experts is Professor Imr
Zs-Nagy. He said, “Centrophenoxine
has shown many facets to improve
conditions related to my membrane
hypothesis of aging. For example, its
ability to improve brain performance,
survival time in animal experiment and
to remove the cell-aging pigment called
lipofuscin. It has been my anti-aging
supplement for more than 30 years.”
12
AGINGMATTERS
Centrophenoxine improves
acetylcholine levels in the brain. It is
this neurotransmitter that declines in
Alzheimer’s disease. The target is at the
early stage of dementia or even before
then at the anti-aging stage, wherein
smart drugs like centrophenoxine
improve/enhance and protect the
performance of an aging but otherwise
recognised as a healthy individual.
General cognitive benefits
Lipofuscin is a waste material that
accumulates in aging cells especially
those in the brain, heart, lungs and
skin. In skin cells, Lipofuscin can form
part of the pigmented spots that are
often referred to as ‘age or liver spots’.
Lipofuscin accumulation can be very
troublesome for the cell because it
inhibits proper functioning taking place,
reducing the transference of chemicals
through cell walls thus damaging both
messaging and detoxification abilities.
When there are significant amounts of
Lipofuscin present in the brain they are
then referred to as ‘plagues’ and then
become a recognised trait of Alzheimer’s.
Do you get bored easily?
Centrophenoxine’s primary mode of
action is to help remove lipofuscin
deposits. Patients that take
Centrophenoxine possibly over a couple
of weeks can see aging spots fade or
disappear. Whilst knowing, at the same
time, Lipofuscin is reducing in their
heart, lungs and brain.
further evaluation. Which of the following
is your issue?
Short term memory
Medium term memory
Long term memory
Do you lack focus/attention?
Does your mind quickly become tired?
Is the problem remembering new
experiences?
Does it take you too long to recall
memories?
Centrophenoxine is best suited to the
last one. It can help people especially
those over 40 to hasten their recall
speed, bringing clarity and order to both
speech and thought. A typical dose for
the average person is 250mg once or
twice daily.
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
SPOTLIGHT
DEPRENYL
DEPRENYL FOR FOCUS AND
CONCENTRATION
Deprenyl is also known as selegiline, it
was created in the 1960s by Professor
Joseph Knoll, principally as an aid to
Parkinson’s patients - because deprenyl
has a significant benefit to improve
dopamine levels in the brain.
Significant longevity studies
Professor Knoll’s experiments on rats
produced incredible longevity benefits.
When fed deprenyl in their food, they
lived longer than those that were not.
After the last non-treated rat died, the
first of the deprenyl treated rats hadn’t!
These results were in another study
conducted from research by, Dean,
Fowkes and Morgenthaler - published in
the book, ‘Smart Drugs and Nutrients’.
It highlights that the loss of dopamine
in humans with age, can be mapped
against the development of Parkinson’s
and even death.
Deprenyl has been expressed as a
MAO-b inhibitor. Preventing the enzyme
monoamine-oxidase type-b from
destroying dopamine, ergo leading
to its greater availability in the brain.
The inhibition of the more common
MAO-a can be problematic, leading to
something called ‘the cheese effect,’
not a side effect of deprenyl, although
it should be noted that dopamine can
inhibit type-a, usually at very high doses
of 20mg. Professor Knoll has noted that
there is another significant action of
deprenyl and this is the raising of PEA
levels. PEA is a catecholamine activity
enhancer that raises norepinephrine
levels, it’s a significant attention agent
that is behind the primary mechanism
of the famous Eugeroic drug- modafinil
(Provigil). Read Professor Knoll’s books ‘The brain and its self’, or ‘How selegiline/
deprenyl slows brain aging.’
Typical patient responses
A patient who has mild cognitive
impairment, or age related minor
cognitive dysfunction, the most common
report is a significant improvement in
their focus and concentration. Persons
with higher dopamine levels often
appear more ‘driven’ and ‘dedicated.’
Some advocate one week off in the
month and others use it during the
weekdays but not at the weekends.
Doses are based on need and age.
Parkinson’s patients will require large
doses. A person wanting to improve
their cognitive performance may want
to consider 1mg to 3mg per day, with
occasional breaks. These doses do
not take into account synergy with
other dopamine enhancing agents and
persons using anti-depressants should
consult with their physician. Deprenyl
tablets are provided in 5mg form
(Jumex), some like to take ½ to 1 of these
tablets 3-times a week. The use of the
deprenyl liquid (Dep-Pro) is particularly
attractive for those using deprenyl to
generally support, protect and improve
neurological function, since 1 drop
= 1mg, the liquid can be dosed very
precisely by placing those drops into a
cold drink. Avoid use in the late evening
to prevent any sleep disruption.
Avoid overuse since it can lead to
what may appear to be an oppressive
behavior, as others around you are not
so focused and ‘on the ball’ as you! We
recommend breaks from deprenyl use.
AGINGMATTERS
13
SPOTLIGHT
PIRACETAM
PIRACETAM, THE ORIGINAL
NOOTROPIC
Piracetam, the original
nootropic
Smart drugs and nutrients, or to give
them their correct medical terminology,
nootropics are agents that can improve
conditions of senile dementias and have
become popular for older individuals
to improve their mental and cognitive
processes. It was Ward Dean, M.D. who
highlighted these facts through his very
popular ‘Smart Drug’ series of books in
the 1980s, since then the term ‘smart
drugs’ has become mainstream.
This smart drug was first developed
by Dr. Giurgea for UCB laboratories
in Belgium in the 1960s. Originally it
was designed to assist with travel and
altitude sickness, but shortly afterwards
individuals realised that piracetam had
positive cognitive enhancement effects.
14
AGINGMATTERS
Piracetam is a cognition agent that has
been used successfully to treat a wide
range of conditions, for example, it has
been shown to increase a person’s
attention levels and improve memory
and intelligence. Piracetam can help to
slow down ‘senile involution’, dementia
and Alzheimer’s disease. In tests and
trials, piracetam induces significant
improvement to memory consolidation
and recall in those suffering from ‘ageassociated memory impairment’. It has
also been used to improve patient’s
recovery from strokes, particularly
improving post stroke speech
impairment (aphasia). Another use has
been in cases of acute and chronic
cerebral ischaemia, (decreased blood
flow to the brain). Using piracetam has
restored speech and the use of limbs
in these patients; it has also increased
neuronal activity in the brain when
measured with EEG.
For regular individuals, piracetam has
been shown to enhance idea creation
and the ability to ‘see things through’.
The level of clarity piracetam creates is
often described, “the fog has lifted.”
How does piracetam work?
Piracetam’s key and unique method of
action is upon the Corpus Callosum,
the region of the brain that links the
two hemispheres. Most experts believe
it is the key that gives piracetam users
the ability to channel greater brain
potential by connecting the logical
side of the brain with the creative
side more effectively.
What are the doses of piracetam?
A common dose is 800mg tablets
three times a day, then lowering to
800mg twice a day after the first
month. The effects of piracetam can
be enhanced if taken concurrently
with centrophenoxine or Hydergine.
Side effects are minimal and seldom
experienced, but should you
experience nausea or a headache
then it is usually caused by an overdose.
In which case reduce the dose and
build up more slowly.
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
SPOTLIGHT
MZS
BECAUSE NOT ALL MELATONINS What does Melatonin do?
ARE CREATED EQUAL
Melatonin is produced by the pineal gland
at night to regulate our circadian rhythm,
(sometimes called the sleep wake cycle).
As we age the amount of melatonin we
produce reduces, resulting in many older
people sleeping less and having
a lower quality of sleep. Our melatonin
has been formulated by the world’s
foremost melatonin expert Dr. Walter
Pierpaoli, his Melatonin Zn Se, or MZS,
is totally unique since it is designed to
mimic the natural night peak of melatonin
to leave you feeling refreshed and alert
the following day.
Melatonin is vital to protect our
hormonal system, regulate immunity and
repair our body’s cells. Commonly used
by shift workers and to treat jet lag and
age related sleep disorders. Melatonin
is an extremely effective antioxidant, in
fact on a molecule to molecule basis melatonin has proved to be significantly
more efficient in neutralizing toxic
hydroxyl radicals than the two wellknown
free radical scavengers, glutathione and
mannitol. Its effect on longevity is well
documented. Experts believe melatonin
has a positive effect on aging.
Age related macular degeneration
(ARMD) comes in two forms, wet and
dry. It’s a difficult disorder to treat and
linked to blindness. A 24-month study,
(published in NY Academy of Science,
2005, 1057:384-392) on 100 patients
showed that after 3 months, the majority
of patients taking 3 mg of Melatonin
Zn Se nightly had halted the
progression of their age related macular
degeneration and at 6 months many
showed reversal of their ARMD. True for
both the wet and dry forms!
Why is Dr. Pierpaoli’s MZS
more effective than other
melatonin supplements?
Firstly, it is of pharmaceutical quality at
a dose of 3 mg. Secondly, it contains the
synergistic ingredients of selenium and
zinc. Thirdly and most importantly- it is
designed to release at a very specific
time. Dr. Pierpaoli’s research led him to
perfect a formula that exactly mimics
the pineal gland’s release of melatonin.
MZS is the only melatonin supplement to
follow nature’s own night peak. Take half
to one 3 mg tablet at bedtime only; do
not take more than two tablets. By taking
MZS™ between 9pm and 11pm you will
create a night peak between 1am and
3am, this is the most natural and normal
time to have the highest melatonin
levels.
MZS is much more than a sleep aid and
melatonin has many published benefits.
MZS comes with the endorsement of Dr.
Pierpaoli. If you’ve tried other melatonin
and didn’t notice any significant effect,
then we highly recommend you try
Dr. Pierpaoli’s MZS for a superior
experience.
AGINGMATTERS
15
CATARACT &
™
CAN-C
16
AGINGMATTERS
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
CAN-C
CAN-C™
The non-surgical cataract treatment
I
t’s good news… Eye surgery is no
longer the only option available if
you suffer from conditions such as
cataracts, or blurred vision.
Can-C™ eye-drops give the opportunity
to take control of various eye conditions.
Helping to turn back the hands of time
on what was once thought of as just
being part and parcel of growing old,
but can now in many cases be treated
effectively, without the need for any
invasive procedures at all.
Thanks to remarkable Russian research,
Can-C™ eye-drops offer a genuine
alternative to surgery. Now, cataracts can
be treated simply by the daily use of
eye-drops. Specifically designed for the
treatment of senile cataracts and using
a unique, patented formula containing
the active and natural ingredient
N-acetylcarnosine. Can-C™ eye-drops
gently but effectively can slow, halt and
even reverse the progress of cataracts.
And the results are evident incredibly
quickly. Even after just 1 month of
treatment, the effects of Can-C™
eye-drops are clearly visible - breaking
down the impaired proteins in the
crystalline of the lens that cause
the cataracts.
These are degenerative conditions
caused by excessive oxidation (free
radical damage-free radicals are toxic
by-products of your everyday
metabolism).
With aging, the production of these
free radicals increases, whereas the
body defences against them become
less effective. Free radicals destroy
proteins, enzymes and DNA causing
chronic damage to tissues. A related
process known as glycation is also
strongly implicated; this process which
conveniently abbreviates to AGE
(advanced glycated end-products) is
one where oxygen and glucose impair
protein by cross-linking them.
Can-C™ is the original N-acetylcarnosine
(NAC) eye-drop formula. The drops have
been commercially sold since 2001 and
in that time has helped many thousands
of people treat their senile cataracts
without the need for surgery. In fact, it
is estimated that there have now been
more than 50,000 documented patient
cases of Can-C™ use.
Cataract is the leading cause of
blindness and accounts for about 42%
of all such cases worldwide. More than
17 million people around the world
are blind because of cataract and
an alarmingly, 28,000 new cases are
reported every day. Chronic,
age-related visual problems such as
cataract, macular degeneration and
glaucoma have one basic similarity.
AGINGMATTERS
17
CAN-C
CATARACT &
™
CAN-C
WITH CAN-C™, YOU GET TO
KEEP YOUR NATURAL LENS
Vision may be the most precious of our five senses. Yet most
of us take it for granted until it begins to deteriorate with age.
Many thousands of patients using the eye-drops have noticed
improvements of their vision, ranging from mild improvement
to complete resolution of the condition. According to the
manufacturers of Can-C™ lubricant eye-drops, with over half
a million bottles sold worldwide. This means that many people
have retained their natural lens and not needed to have it
replaced by a plastic one. It should be obvious that a plastic
lens does not have the optic accommodation and capacity of
a natural one.
VISION IS PRECIOUS. PICTURES
ARE WORTH A THOUSAND WORDS
So many times we hear people say, “My eyes aren’t what they
used to be.” The simple fact is… they most probably aren’t. But
that’s life, we get older and our bodies change. However, you
don’t have to sit back and give up hope for improved vision.
18
AGINGMATTERS
THE CATARACT EYE-DROP
TREATMENT IS A PROVEN
AND SCIENTIFIC ONE
AND BASED ON CLINICAL
EXPERIENCE
If you are frustrated with your eyesight, ask yourself
these questions:
Are my eyes sensitive to light; or do I get cloudiness
in parts of my vision?
Which problem do I deal with first? My difficulty
driving at night, the overwhelming glare or my
increased near sightedness?
When did this start happening to me? Is it stable or
getting worse?
Why is this happening to me?
You could be the fittest person in the neighbourhood
but your eyes may tell a different story.
Everyone has their story. As we talk to customers all
the time, they ask questions and we help to provide
the answers.
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CAN-C
LOOK TO YOUR FUTURE WITH
CLEARER VISION
The statistics in the human trials for Can-C™ show that
N-acetylcarnosine eye-drops applied for 6-months twice daily
into the eye, in patients, all suffering from senile cataract, had
the following results:
1. 88.9% had an improvement in glare sensitivity.
2. 41.5% had an improvement of the transmissivity
of the lens.
Some examples:
Can Can-C™ be taken in conjunction with other
common eye supplements such as lutein and
zeaxanthin / astaxanthin?
We do not recommend that the Can-C™ eye-drops are
combined with lutein (unless a patient has a cataract
associated with a retinal disorder), this is because lutein appears to interfere with the same receptor sites as
NAC and may lower the efficacy of the eye-drops. You
should stop taking lutein for at least the first 6 months
but after this period they may be started again. This
is because Can-C™ does the majority of its restorative
work in that period and thereafter it is maintenance,
thus a reduced efficacy is not so essential. The same
is true for zeaxanthin; however we are not aware of
contraindications with astaxanthin.
3. 90% had an improvement in visual acuity.
Note: You can also maximise the benefit of using Can-C™
eye drops by taking Can-C™ Plus capsules. They are especially
recommended in difficult cases, or for ripe cataracts
(cataracts that have existed for a long time). So those who
have very dense cataract and severely diminished vision to
start with should combine the capsules with the eye-drops
from day one.
The Can-C™ products can assist with lots of other eye
conditions, such as:
• Dry eye syndrome
• Contact lens comfort (both as a lubricant and also because
they block the painful accumulation of lactic acid which is
caused by the contact lens rubbing onto the eye).
• Corneal disorders
How long has Can-C™ been available?
Can-C has been sold since 2001 and in that time has
helped thousands of people treat their senile cataracts
without surgery.
Are there any problems using Can-C™ concurrently
with other eye-drops for glaucoma pressure
control? Would you recommend use of both?
To date, there have been no noted contraindications
or side effects noted with the use of other eye-drops
combined with Can-C™, but naturally, as there are so
many versions, not all eye-drops have been tested
along with the same. Dr. Mark Babizhayev (the inventor
of the technology) has stated that beta blocker
eye-drops used for glaucoma may actually have
additional benefit when combined with Can-C™ to
help further reduce the intraocular pressure.
• Computer vision syndrome
• Eye strain
• Ocular inflammation
• Blurred vision
• Presbyopia
• Retinal issues
• Vitreous opacities and lesions
• Complications of diabetes mellitus and other systemic
diseases
• Open-angle primary glaucoma
Can-C™ is a non-surgical cataract treatment. No risk, no large
medical bills and no time off work! The reasons you should
look after your eyes are many, especially when you consider
the potential risks involved with surgery.
AGINGMATTERS
19
CAN-C
SHORT TERM CATARACT
SURGERY COMPLICATIONS
Cataract surgery may be the most
performed surgical procedure in
the world, but it is not without its
problems and complications – for
example, 24 hours after surgery
the following can occur:
•
Bleeding - inside the back of the eye
and inside the front of the eye where
the actual surgery is being performed.
•
Bruise or ‘black eye’ - if it was
necessary to use an injection around
your eye you may experience some
temporary bruising.
•
Wound or incision leak - sometimes
the corneal incision does not seal
properly and may leak.
•
Endophthalmitis or ‘inner eye
infection’ - an infection after cataract
surgery is rare but can occur.
•
Rupture of the posterior capsule during cataract surgery, the cloudy or
opacified lens material is ‘chopped up’
and suctioned to remove it from the
eye. Occasionally it is possible that
the posterior lens capsule will tear or
rupture during surgery.
LONG TERM CATARACT SURGERY
COMPLICATIONS
Long term cataract surgery problems and complications are
those that we will define as occurring from one week to as
long as six months after cataract surgery.
Decentered or dislocated intraocular lens implant (IOL) the artificial lens implant (IOL) used to correct your vision after
cataract surgery can move slightly becoming decentered or
move a greater amount and become dislocated.
Cystoid macular edema - during the first three months or so
after cataract surgery it is possible for the macula, the visual
center of the retina, to be susceptible to microscopic swelling.
•
Retinal detachment - if you are
extremely near-sighted you may be
at greater risk for retinal detachment
in general and especially when you
have any type of eye surgery including
cataract surgery.
•
Glaucoma - in general, secondary
Glaucoma after cataract surgery is
very unusual. However, if there is
other bleeding or inflammation it can
predispose the development of
secondary Glaucoma.
•
Significant astigmatism in the event that it was necessary to
use sutures or stitches- because the
corneal incision did not seal properly,
it is possible to distort the shape of
the cornea and induce astigmatism.
This is just an overview of the possible complications of
cataract surgery. Of course, none of the information provided
here is meant to be a substitute or replace your physician’s
consultation nor does it replace the need for you to consult
with your surgeon about specific details of cataract surgery
complications.
KNOWLEDGE IS POWER
“Life begins at 40 – but so do fallen arches, rheumatism, faulty
eyesight, and the tendency to tell a story to the same person,
three or four times.”
- Helen Rowland
ADDITIONAL READING ON THIS TOPIC
Secondary or after cataract - the most common complication
of cataract surgery is opacification of the posterior lens
capsule resulting in the formation of a secondary cataract,
which occurs after as many as 30% of cataract surgery
procedures. When this occurs you will experience a gradual
blurring of your vision. Here, the surgeon uses a YAG laser to
perform a procedure called a YAG laser capsulotomy in which
a small opening is created in the cloudy membrane.
20
AGINGMATTERS
Dr. Mark Babizhayev is one of the principal Russian
researchers behind the development and use of
N-acetylcarnosine or NAC eye-drops. In his interview, he
discusses with Phil from International Anti-Aging Systems
(IAS) some of the results of his research.
Read the whole interview here:
www.antiaging-systems.com/articles/172-interview-with-mark
-babizhayev-phd-about-the-development-of-can-c-eye-drops
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Can-C
TM
2x5ml Eye drop bottles
Buy 3 Save 10%
Buy 6 Save 20%
$39.99
Can-C™ Plus is the perfect accompaniment
to Can-C™ Eye Drops.
Maximise the benefit from day one of the Can-C
eye-drops. Those who have very dense cataract and
severely diminished vision to start with should combine
the tablets with the eye-drops from day one.
All side effects and contraindications are available on the IAS website.
AGINGMATTERS
21
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
Restrictions
may apply, please see IAS terms and conditions for full details. Offer valid until
1st June 2017
PEOs
22
AGINGMATTERS
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PEOs
PEOs
The “Real” Essential Fatty
Acids, Demystified
W
hen it comes to nutrition, there’s
often a fair amount of controversy
and confusion concerning
research on a particular food ingredient or
dietary supplement. For example,
health-conscious consumers want to know:
Should we drink coffee or tea? Or red
wine? Eat dark chocolate? Use margarine
instead of butter? How about omega-3 and
omega-6 essential fatty acids (EFA’s - the
topic of this article): what are they exactly,
which ones do we need, and should we
get them from fish oil or plants? Observing
the plethora of health issues in our
modern world that still remain unresolved
despite the supposed promise of fish
oil supplements, Brian Peskin, engineer
and founder of Life-Systems Engineering
Science has focused his recent career on
getting to the bottom of the plant versus
fish fatty acids controversy by thoroughly
examining the medical literature, including
results of countless studies.
His verdict: discard the fish oil capsules,
obtain high quality omega-3 and omega-6
EFA’s (which Peskin has re-labeled “Parent
Essential Oils,” or “PEO’s”) from plant-based
sources, and enjoy myriad health benefits
as a by product.
In this article, we’ll clear up the confusion
about EFA’s (in fact, we’ll see that fish oil
supplements technically don’t contain EFA’s
at all!) by examining the chemical definition
of “essential fatty acids;” their functions and
health benefits; general misconceptions
and proven facts concerning EFA’s; the
plants versus fish oil debate; and how to
incorporate these essential nutrients into
your daily health regimen.
AGINGMATTERS
23
PEOs
PEOs
ESSENTIAL FATTY ACIDS 101
Let’s start out by precisely defining “essential fatty acid.” (But
we’ll need to look at some chemistry, so please stick with me.)
EFA’s are long-chain polyunsaturated fatty acids (PUFA’s), which
means they are chains of multiple carbons (18 or more)
containing more than one double bond. They are classified as
“essential” because they cannot be synthesized in the body
and must be obtained from the diet.
Figure 1a. Structures of fatty acids
CH3 CHCH2(n) COOH
hydrocarbon carboxyl end
chain
The general structure of a fatty acid (20)
EFA’s and other PUFA’s are named according to the position
of the first double bond in the carbon chain: in omega-6 fatty
acids, the first double bond is located between the sixth and
seventh carbon atoms from the methyl end of the fatty acid,
and in omega-3’s, the first double bond is located between
the third and fourth carbon atom from the methyl end. Fatty
acid chains are not straight, but rather are crimped due to the
presence of double bonds (as shown in Figure 1c).
24
AGINGMATTERS
Figure 1b. Structures of fatty acids
The chemical structure of α-linolenic acid
(ALA) has 18 carbon atoms (C) and 3 double bonds,
the first of which is located 3 carbon atoms from the
terminal methyl group (omega [ω] end)
The two — and only two — EFA’s are alpha-linolenic acid (ALA,
an omega-3) and linoleic acid (LA, an omega-6), both containing
18 carbons. They are called “parent” compounds because they
are the starting materials, or precursors, that the body uses to
manufacture other longer-chain fatty acids (called “derivatives”
or “metabolites”) with 20 or more carbons. For example,
humans can synthesize longer-chain omega-6 fatty acids, such
as dihomo-γ-linolenic acid (DGLA; 20 carbons) and arachidonic
acid (AA; 20 carbons) from LA, and longer-chain omega-3 fatty
acids, such as eicosapentaenoic acid (EPA; 20 carbons) and
docosahexaenoic acid (DHA; 22 carbons) from ALA.
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PEOs
Figure 1c. Structures of fatty acids
The molecular stuctures of dietary omega-6 and omega-3 fatty acids. The presence of a double
bond in the hydrocarbon chain of polyunsaturated fatty acids (PUFA) introduces a “kink” in the
molecule, creating different secondary structures that influence physical properties(5).
Figure reference: http://lpi.oregonstate.edu/mic/other-nutrients/essential-fatty-acids
Both parent compounds, or EFA’s, are found in plant sources:
LA in leafy vegetables, seeds, nuts, grains, and vegetable oils
(such as evening primrose oil, as well as in less desirable
processed vegetable oils, such as corn and sunflower oils);
and ALA in flaxseed, hemp, canola, soybeans and walnuts.
Omega-3 fatty acid derivatives EPA and DHA, as mentioned,
are synthesized endogenously from ALA, but can also be
derived from cold water oily fish such as salmon, herring,
mackerel, sardines and albacore tuna; they are also the major
components in fish oil supplements (which we’ll discuss in
more detail later).
So, by definition, there are only two essential fatty acids: ALA
(parent omega-3) and LA (parent omega-6), both of which are
plant-derived nutrients that must be obtained from the diet.
Not only are they important in the normal functioning of all
tissues of the body, but they also act as precursors to other
fatty acids.
AGINGMATTERS
25
PEOs
TECHNICALLY, PEO = EFA
As mentioned, Brian Peskin has dedicated himself to the
study of EFA’s; he’s pored over medical textbooks and relevant
published journal articles to evaluate the health benefits of
EFA derivatives (especially EPA and DHA) compared to parent
compounds ALA and LA, and has made a determination
in favor of the parents: he strongly advises against the use
of derivative-containing fish oil supplements which may be
ineffective, even detrimental to health, and recommends
supplementation with nature’s essential starting materials,
parent omega-3 (ALA) and parent omega-6 (LA). Peskin has
re-labeled these — the only two — essential fatty acids “Parent
Essential Oils” (“PEO’s”), mainly to avoid the confusion over and
misuse of the term “EFA,” which is sometimes misleadingly or
mistakenly applied to derivatives. For example, a Google search
of “EFA’s” reveals many inappropriately labeled products on the
market which are, in fact, derivative-containing fish oil capsules,
like this one: [manufacturer name excluded] “Mega EFA
Omega-3 EPA & DHA Fish Oil” — what a mouthful, and wrongly
labeled “EFA.”
For our discussion, since we’ve already reviewed precise
chemical definitions, “PEO” will be used interchangeably
with “EFA;” “ALA” with “parent omega-3;” and “LA” with
“parent omega-6.”
NOT ENOUGH ATTENTION
PAID TO PARENTS!
It seems that when it comes to PUFA’s,
the bulk of marketing and media
emphasis has been unduly placed on
derivatives (especially fish oil-derived
EPA and DHA), not parents ALA or LA.
Although derivatives provide an array
of health benefits, parents are essential
nutrients (remember, we are unable
to synthesize them), and substantial
published information supports their
inclusion in a healthy diet. So why are
parent omega-3 and parent omega-6
so important?
First, they play an integral role in the
structure and function of the cell
membrane, a thin lipid bilayer composed
of two sheets of phospholipid molecules
that form a continuous barrier around
every cell (and we have 100 trillion of
them) in the body.
26
AGINGMATTERS
ABBREVIATIONS:
PUFA: polyunsaturated fatty acid (EFA’s and
derivatives are PUFA’s.)
EFA = essential fatty acid
PEO = parent essential oil
EFA = PEO, of which there are only two:
ALA = alpha-linolenic acid = parent omega-3
LA = linoleic acid = parent omega-6
Some EFA derivatives:
DGLA = dihomo-γ-linolenic acid (omega-6)
AA: arachidonic acid (omega-6)
EPA: eicosapentaenoic acid (omega-3)
DHA: docosahexaenoic acid (omega-3)
Peskin has co-authored a book, along with Robert
Rowen, MD, entitled “PEO Solution, Conquering Cancer,
Diabetes and Heart Disease with Parent Essential Oils,”
in which he outlines several interrelated facts as well
as misconceptions concerning EFA’s and derivatives,
which we’ll now discuss.
This membrane protects the cellular
contents and internal machinery
from the external environment while
selectively allowing nutrients into, and
waste products out of the cell. Research
shows that fatty acids consumed in
the diet become incorporated into
the phospholipid bilayer and affect
cell membrane composition and
properties such as fluidity, flexibility,
permeability, and enzyme activity.(1,2)
So a diet rich in saturated fat will result
in cell membranes that are structurally
different and less fluid than those that
incorporate EFA’s(2) (and that’s just one
good reason to make the switch
to EFA’s!).
Besides membrane composition and
function, EFA’s in the lipid bilayer also
play a role in transporting oxygen,
necessary for cellular respiration and
other vital processes, into the cell.
An EFA deficiency resulting in lower
availability of oxygen for cellular
respiration may lead to health
consequences, and Peskin believes that
insufficient cellular oxygenation (hypoxia)
is the prime cause of cancer. Peskin
refers to parents as “oxygen magnets”
that can stem cancer and other
disease processes. EFA’s also act as
precursors to bioactive mediators such
as eicosanoids (including prostaglandins,
thromboxanes, leukotrienes, etc.),
chemical messengers that play critical
roles in immune and inflammatory
responses. They can also modulate the
expression of various genes.
So we can see that parent compounds
play many key cellular roles, despite the
relative lack of popular and marketing
emphasis compared with fish oil
derivatives.
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PEOs
OMEGA-6 FATTY ACIDS NOT GIVEN THEIR
DUE RESPECT
THE BODY ONLY PARTIALLY CONVERTS
PARENTS TO DERIVATIVES, THAT’S ENOUGH
It also appears that most of the popular attention has been
placed on the supposed health benefits of the omega-3 series
(especially derivatives), ignoring that unadulterated, high quality
omega-6’s are also vital to good health. Omega-6 seem to have
developed a bad reputation for a couple of reasons. The first
involves the LA metabolite arachidonic acid (AA), thought to
contribute to pro-inflammatory processes and heart disease.
However, according to one researcher, “this perspective fails
to consider several inconvenient facts(3)," such as that dietary
intake of LA does not significantly affect AA levels in the
body(3,4). “Virtually no evidence is available from randomized,
controlled intervention studies among healthy, non-infant
human beings to show that addition of LA to the diet increases
the concentration of inflammatory markers(3)." Myth debunked.
A medical fallacy concerning omega-3’s (that at least in
part drives the success of the fish oil industry) is that ALA
should ideally completely metabolize to EPA and DHA in the
body, and that, since research has shown that conversion
is limited in humans, then this must mean that most people
are deficient in these longer-chain derivatives. This naive
assumption is repeatedly challenged in Peskin’s book, in
which he states that the “body makes derivatives as needed,”
with conversion rates set naturally low. Only 5% of ALA is
metabolized to EPA and even less (less than 1%) to DHA(6).
And for healthy individuals, these conversion rates should
be sufficient to maintain tissue function(7).
Another reputation detractor concerns the quality of omega-6
in the typical Western diet, which is, in two words, largely
adulterated (chemically altered). LA in commercial cooking oils
is typically highly modified in multi-step processes that include
the use of solvents, high temperatures, and additives in order
to hydrogenate or interesterify the fatty acids, resulting in
products that last longer, but are dangerous to health, with
adverse effects on cardiovascular health(4). But unadulterated
LA-rich oils reduce risk of cardiovascular disease and should be
consumed as part of a healthy diet(4), pointing to the need to
eliminate hydrogenated vegetable oils and replace them with
high quality oils such as safflower, sesame, and sunflower.
Even more so than saturated fat, Peskin believes that “the real
culprits” responsible for the abundance of health problems
in the modern world are highly processed, chemically altered
fats, and that “good health requires a preponderance of
[unadulterated, high quality] dietary parent omega-6,” with a
higher ratio of omega-6 to omega-3 fatty acids. Ideally, this
ratio should be between 1:1 and 4:1(5).
Consider that the net rate of DHA (the most abundant PUFA
in the brain) consumed by the brain is only about 2 to 6 mg
per day(8). This underscores the fact that, although the body
needs a certain level of derivatives for proper functioning, our
physiology does not depend on the mega doses of DHA and
EPA that many doctors prescribe in the form of fish oil; in fact,
as we’ll see in the next section, ultra-high doses of derivatives
could be doing us harm. According to Peskin, EPA and DHA
act as “biological antifreeze to fish living in frigid waters.
Humans don’t require such copious amounts because we
have an internal temperature of 98.6 degrees F.”
Interestingly, a study comparing the effects of dietary
patterns on omega-3 PUFA status found that women on
vegan diets actually had higher blood levels of long-chain
omega-3’s compared with fish-eaters(9), which demonstrates
that by adhering to a plant-based diet (rich in EFA’s), they
manufactured ample DHA and EPA without consuming fish
or fish oil.
AGINGMATTERS
27
PEOs
OVER-ESTIMATION OF DHA AND EPA
REQUIRMENTS LEADS TO FISH OIL
OVERDOSING AND ITS CONSEQUENCES
As just explained, the body metabolizes ALA to longer-chain
EPA and DHA to a limited degree that is sufficient to maintain
normal tissue function, a fact that is often unrecognized,
overlooked, or ignored as doctors prescribe excessive
doses of fish oil in an attempt to improve cardiovascular
and other health problems. This results in patients reaching
supra-physiological blood levels of derivatives (dozens,
even hundreds of times more than the body manufactures
naturally, depending on the particular supplement and amount
consumed), leading to unresolved or even exacerbated
problems. Peskin argues that excess omega-3 derivatives end
up in unusual places they don’t belong: skin, cardiovascular
system, prostate, and breast tissue, where they can potentially
lead to increased rates of prostate cancer, skin cancer,
and heart disease. Recent large studies have in fact shown
increased risk of prostate cancer in men with higher blood
MAKE THE SWITCH - YOUR
HEALTH DEPENDS UPON IT
Earlier, we took a glimpse at the
important biological roles parent
compounds play on a cellular level: as
major constituents of cell membranes,
as precursors to chemical messengers,
and as transporters of oxygen into the
cell. On a whole-body level, EFA’s are
cardio-protective; prevent certain types
of cancer; and benefit normal brain
development and function, inflammatory
disorders, and diabetes, with the
added cosmetic effect of improving
skin, hair, and nails. But in order to
be effective, sources of EFA’s must be
References
AGINGMATTERS
And although a large body of scientific research suggests that
higher omega-3 fatty acid intake is associated with reductions
in cardiovascular disease risk, other recent studies in the New
England Journal of Medicine(11), Journal of the American Medical
Association(12), and Archives of Internal Medicine(13) find the
opposite: fish oil derivatives do not improve cardiovascular risk
factors. (However, parent omega-3 (ALA) does lower the risk of
heart disease(6), as does parent omega-6 (LA)(4).)
Nor does fish oil slow cognitive decline, as was previously
thought. A large study performed at the National Eye Institute/
National Institutes of Health tested the effect of various
supplements, including omega-3’s, on cognitive function in
over 3500 subjects (average age 73) and found no statistically
significant effect(14).
We can only conclude that fish oil is not all it’s cracked up to be.
organic and unprocessed and in the
correct physiologic ratio. A plant-rich
diet that includes ample amounts of
natural foods such as ground flaxseeds,
walnuts, leafy vegetables, seeds, nuts,
and unprocessed vegetable oils will
provide more than the necessary daily
requirements for EFA’s. However, for
those whose diets fall short, Peskin
has formulated a product called PEOPro™ containing organic, unprocessed
ingredients: evening primrose oil,
sunflower oil, flax oil, pumpkin oil,
and extra-virgin coconut oil, in a
ratio of approximately 2:1 omega-6:
omega-3. The recommended dose is
four capsules per day, which provides
1. http://lpi.oregonstate.edu/mic/other-nutrients/essential-fatty-acids
2. Hussein JS. Cell Membrane Fatty Acids and Health. International Journal of Pharmacy and Pharmaceutical
Sciences.2013;5(3):38-46.
3. Harris WS, Shearer GC Omega-6 fatty acids and cardiovascular disease: friend, not foe? Circulation. 2014
Oct 28;130(18):1562-4.
4. Anton SD, Heekin K, Simkins C, Acosta A. Differential effects of adulterated versus unadulterated forms of
linoleic acid on cardiovascular health. J Integr Med. 2013 Jan;11(1):2-10.
5. Simopoulos AP. Essential fatty acids in health and chronic disease. Am J Clin Nutr.1999;70:560S-569S.
6. Rajaram S. Health benefits of plant-derived α-linolenic acid. Am J Clin Nutr. 2014 Jul;100(1):443S-8S.
7. Williams CM, Burdge G. Long-chain n-3 PUFA: plant v. marine sources. P Nutr Soc. 2006;65:42-50.
8. Umhau JC, Zhou W, Carson RE, et al. Imaging incorporation of circulating docosahexaenoic acid into the
human brain using positron emission tomography. J Lipid Res. 2009 Jul;50(7):1259-68.
9. Welch AA, Shakya-Shrestha S, Lentjes MAH, Wareham NJ, Khaw KT. Dietary intake and status of n-3
polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians,
and vegans and the precursor-product ratio of a-linolenic acid to long-chain n-3 polyunsaturated fatty
acids: results from the EPIC-Norfolk cohort. Am J Clin Nutr. 2010;92:1040-1051.
28
levels of long-chain omega-3 derivatives (but reduced risk of
cancer with higher parent omega-6 (LA) levels(10)).
almost 3g of EFA’s. We have just seen
the “power of the parents” and hopefully
unraveled the myths and cleared up the
misconceptions concerning EFA’s and
their derivatives. To sum up, here’s the
ideal way to meet your requirements for
these essential nutrients: eliminate both
fish oil capsules and highly processed
vegetable oils (and, for that matter, any
processed foods) and replace them
with plant-based sources of high quality,
organic parent omega-3 (ALA) and
organic, unprocessed parent omega-6,
(LA) in the proper ratio. Enjoy vibrant
health as a result.
10. Brasky TM, Darke AK, Song X, et al. Plasma phospholipid fatty acids and prostate cancer risk in the SELECT
trial. J Natl Cancer Inst. 2013 Aug 7;105(15):1132-41.
11. Roncaglioni MC, Tombesi M, Avanzini F, et al. n-3 fatty acids in patients with multiple cardiovascular risk
factors. N Engl J Med. 2013;368:1800-1808.
12. Rizos EC, Ntzani EE, Bika E, Kostapanos MS, Elisaf MS. Association between omega-3 fatty acid
supplementation and risk of major cardiovascular disease events: a systematic review and meta-analysis.
JAMA. 2012;308:1024-1033.
13. Kwak SM, Myung SK, Lee YJ. Efficacy of Omega-3 Fatty acid supplements (eicosapentaenoic acid and
docosahexaenoic acid) in the secondary prevention of cardiovascular disease: a meta-analysis of
randomized, double-blind, placebo-controlled trials. Arch Intern Med. 2012;172:986-994.
14. Chew EY, Clemons TE, Agrón E, Launer LJ, Grodstein F, Bernstein PS; Age-Related Eye Disease Study 2
(AREDS2) Research Group. . Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient
Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial. JAMA.
2015 Aug 25;314(8):791-801.
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Use our online voucher code:
PEO-5-OFF-0117
PeoPRO™ Liquid
Parent Essential Oils
The True Essential Fatty Acids
8fl.oz / 236ml liquid. $34.99
(usual price $39.99)
Restrictions may apply, please see IAS terms and conditions for full details. Offer valid until 1st June 2017
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
All side effects and contraindications are available on the IAS website.
AGINGMATTERS
29
™
RETIN-PRO
30
AGINGMATTERS
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
RETIN-PROTM
RETIN-PRO™
THE ‘GOLD STANDARD’ TREATMENTS TO REVERSE SKIN WRINKLES
W
hen you picture aging, what
is the first thing that comes
to mind? Most likely it's
wrinkles, lines, furrows and sagging
skin - the external manifestations of
growing older. As the skin is the largest
and the outermost organ of the body,
it’s the most subject to the damaging
effects of the environment. The skin
is unique in that it undergoes aging
both from the inside, as a result of a
genetically programmed clock, and
from the outside, due to environmental
exposure, particularly UV radiation from
sunlight. The effects of chronic sun
exposure overlaid on the background of
chronological aging are a sure predictor
for pre maturely aged skin.
The good news is that a huge trove of
clinical studies performed over the last
25 years indicates that the detrimental
aging-induced structural and cosmetic
skin changes compounded by cumulative
UV radiation can be improved, and even
reversed, by the topical use of vitamin
A derivatives known as retinoids. In
particular, we’ll look at one of these
analogs, tretinoin, the active ingredient
in Retin-Pro™ cream and micro-gel.
Tretinoin is the most widely investigated
and possibly the most potent retinoid
to treat the combined effects of the
internal and external assaults to the skin.
WHAT CAUSES SKIN TO AGE?
Skin is a complex organ comprising various structures and
cell types that play a variety of roles, including protection
from the environment, heat regulation, immune response,
water and electrolyte balance, among others.(1) Skin aging is a
complicated biological process resulting from what scientists
call intrinsic (internally produced) and extrinsic (external)
factors. Intrinsic, or chronological, skin aging is influenced
by genetics, hormonal changes, smoking, illness, and the
generation of reactive oxygen and nitrogen species as by
products of routine metabolism.(1-3) Extrinsic factors that age
skin include environmental exposure to DNA-damaging agents
such as UV radiation from sunlight, pollution, and smoke.(1-3) By
far, solar UV radiation is the single most destructive element
responsible for prematurely aged skin(1,4,5). Intrinsic skin aging
that occurs simultaneously with chronic UV exposure is known
as photoaging - a combination age-accelerating process that
alters the skin’s structure, function and appearance.
AGINGMATTERS
31
RETIN-PROTM
RETIN-PROTM
WHAT ARE THE DIFFERENCES BETWEEN
PHOTOAGED AND CHRONOLOGICALLY AGED SKIN?
With increasing age, the skin’s
rejuvenation process slows down and
skin loses its suppleness and thickness
due to atrophy of the epidermis (the
outer layer of skin) and degradation of
the dermal extracellular matrix(1)
- the portion of skin tissue other than
cells that is filled by a variety of fibrous
proteins including collagen, elastin and
fibrillin, and polysaccharides known as
glycosaminoglycans. These components
network to form an organized, intricate
structural framework that gives the skin
its elasticity, density and strength. Loss
of these support macromolecules leads
to the thin, dry and saggy appearance
characteristic of chronologically
aged skin.
We’ve already seen that one aspect of
intrinsic aging is increased oxidative
stress due to the generation of reactive
oxygen species (ROS) that damage
skin (as well as internal organs and
tissues). In photoaged skin, repeated
exposure to sunlight sets off a chain
reaction accelerating ROS production
even further, altering gene and protein
structure and function and decreasing
endogenous antioxidant enzymes.(1)
In addition, UV radiation triggers
biochemical pathways associated with
inflammation, decreased immune
response and further degradation of
the epidermis and dermal extracellular
matrix,(1,3,6) including collagen, elastin and
fibrillin loss.(7,8)
These damaging processes lead
to photoaged skin with a yellowish
appearance, fine and coarse wrinkles,
mottled and abnormal pigmentation
(“age spots”), and roughness.(1,2;7-10) In
addition, due to the DNA-damaging
effects of the sun, photoaged skin
is prone to the development of
precancerous and cancerous skin
lesions (1,11). (These features of
photoaging are more common in
white compared with other skin types(2))
So although they share some similar
features such as wrinkles and loss of
skin thickness, chronologically and
photoaged skin do have somewhat
different presentations.
TRETINOIN IS THE ‘GOLD STANDARD’
TOPICAL RETINOID TO REVERSE
PHOTODAMAGE
A variety of methods, including surgery, can improve the
appearance of photoaged skin, but the only therapy that has
stood the test of extensive clinical trials, validating their efficacy in
repairing the dermal extracellular matrix and ameliorating signs
of photodamage is the use of topical retinoids. The retinoid family
comprises vitamin A (retinol) and both its natural metabolites,
including tretinoin, as well as synthetic derivatives. Retinoids
are required for a vast number of biological processes
including embryogenesis, reproduction, vision, immune
modulation,(1) and most importantly for our discussion,
cellular growth and differentiation and the activation of the
skin’s repair mechanisms(1).
32
AGINGMATTERS
Topical retinoids are effective, safe, and even essential in the
treatment and prevention of photo-damaged skin, and were
first introduced for this purpose about 30 years ago.
In the body, retinol is metabolized to several important
products including tretinoin, the carboxylic acid analog, also
known as all-trans retinoic acid. Tretinoin has been used as
a topical therapy for acne, psoriasis, skin cancer, and burns
and, as mentioned, may be the most potent retinoid in
the treatment of photoaging.(1) It is considered the ‘gold
standard’ prescription topical remedy for improving, even
reversing, the fine and coarse wrinkles, sallowness, pigment
abnormalities, and roughness associated with photoaging.
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RETIN-PROTM
HOW TRETINOIN RESCUES
PHOTODAMAGED SKIN
Studies show that topically applied tretinoin increases
epidermal proliferation,(1) promotes the synthesis of
glycosoaminoglycans (a source of hydration that when absent
results in a dull, leathery appearance),(12) blocks inflammation
mediators,(6) and restores the collagen and fibrillin-rich network
of the dermal extracellular matrix(6,8) present in youthful skin.
In addition, tretinoin “primes” the skin to prevent further
matrix degradation by UV, in this way preventing future
skin photoaging(6,9,13). Tretinoin’s tissue-restoring effects are
mediated by the binding to and activation of specific receptors
present in skin, known as nuclear retinoid receptors,(1,6,7)
that are involved in gene expression, protein synthesis, and
cell growth and differentiation and provide the mechanisms
necessary for the repair of photodamaged skin(1).
NUMEROUS STUDIES DOCUMENT
TRETINOIN’S REMARKABLE
AGE-REVERSAL EFFECTS
The first study demonstrating the ability of topical tretinoin
to induce collagen production and eliminate wrinkles was
performed on the photoaged skin of mice in 1984.(14) Then, in
1986, encouraging results from the first clinical trial on human
photodamaged skin(15) spurred a considerable number of
studies. Short-term double-blind trials of three, four and six
months conducted in the late 1980’s and early 1990’s using
various strengths of topical tretinoin cream (typically including
the standard therapy of 0.05% tretinoin) showed statistically
significant improvement in several features of photoaging,
including wrinkles, roughness, sallowness, and abnormal
pigmentation. As an added benefit, the improved appearance
of the skin was accompanied by a ‘rosy glow.’(16-21)
Subsequent long-term studies were performed to evaluate
the effects of continued tretinoin application over months
or years. A 1993 study evaluating 0.05% tretinoin cream
applied daily for 12 months showed that the major degree of
improvement in the signs of photoaging occurred after six months
of use, a trend that continued over time.(22) Histological (tissue)
studies confirmed that observation. By month 12 of daily
tretinoin application, there was an increase in collagen fibers,
a reduction of degenerated microfibrillar material,(23) renewed
epidermal thickness and a return to normal pigmentation.(24) A
more recent 2005 two-year study corroborated these earlier
results. Both visual and histological improvements to skin were
achieved in patients with moderate to severe photodamage by
month 12 of daily 0.05% tretinoin application.(25)
Even those who have taken precautions to avoid the damaging
effects of the sun will gladly welcome emerging evidence that
topical tretinoin may also benefit intrinsically aged skin.(1,9,13)
A study on the daily application of 0.025% tretinoin cream on
chronologically aged inner thigh skin for nine months showed
significant improvement at the tissue level,(26) suggesting that
tretinoin has wide implications in the treatment of both
photoaged and chronologically aged skin.
Although topical tretinoin produces marked improvement,
even reversal, of wrinkles and other signs of photoaging, skin
sensitivity may occur in some individuals, including dryness or
scaling, irritation and redness. The occurrence and magnitude
of these reactions seem to depend on concentration,
frequency of use, product base (cream or gel) and individual
variations.(27)
To address the issue of skin sensitivity, several trials were
conducted to determine the efficacy and tolerability of a low
strength cream, between 0.02-0.025% tretinoin. Researchers
observed significant improvements in the visual and
histological signs of photoaging along with good tolerability
and fewer instances of adverse effects,(28-30) even with
long-term use.(28,30)
AGINGMATTERS
33
RETIN-PROTM
HOW TO USE RETIN-PRO™
Apply a small amount to thoroughly cleansed and dry skin
in the evening and avoid contact with the eyes, corners of
the nose, and mouth. The use of a daily moisturizer such
as NeySkin® is recommended (if moisturizer is used in the
evening, wait 30 minutes after applying Retin-Pro™). Tretinoin
can cause photosensitization, or increased sensitivity to sun.
Avoid sun exposure and use a quality sunblock or sunscreen,
such as Solaris®, and wear protective clothing. Also avoid
weather extremes such as wind and cold, if possible.
As we have just seen, the synergistic effects of chronological
aging compounded with chronic sun exposure can wreak
havoc on the skin. Despite an array of techniques and products
claiming to efface wrinkles, only retinoids have undergone
the battery of clinical trials necessary to clearly establish their
efficacy in reversing the damaging processes involved in
photoaging. One retinoid in particular, tretinoin, is the most
thoroughly investigated of its class and considered the “gold
standard” therapy for treating and reversing wrinkles, age
spots, roughness and sallowness.
References
18. Leyden JJ, Grove GL, Grove MJ, et al. Treatment of photodamaged facial skin with topical tretinoin.
J Am Acad Dermatol. 1989; 21:638–44.
19. Caputo R, Monti M, Motta S, et al. The treatment of visible signs of senescence: the Italian experience.
Br J Dermatol. 1990;122 (Suppl35): 97–103.
20. Weinstein GD, Nigra TP, Pochi PE, et al. Topical tretinoin for treatment of photodamaged skin.
Arch Dermatol. 1991;127:659–65.
21. Bhawan J, Gonzalez-Serva A, Nehal K, et al. Effects of tretinoin on photodamaged skin. A histologic study.
Arch Dermatol. 1991;127:666-72.
22. Green LJ, McCormick A, Weinstein GD. Photoaging and the skin: the effects of tretinoin. Dermatol Clin.
1993;11:97–105.
23. Bhawan J, Palco MJ, Lee J, et al. Reversible histologic effects of tretinoin on photodamaged skin.
J Geriatr Dermatol. 1995; 3:62-7.
24. Bhawan J, Olsen E, Lufrano L, et al. Histologic evaluation of the long-term effects of tretinoin on
photodamaged skin. J Dermatol Sci.1996;11:177–82.
25. Kang S, Bergfeld W, Gottlieb AB, et al. Long-term efficacy and safety of tretinoin emollient cream 0.05%
in the treatment of photodamaged facial skin: a two-year, randomized, placebo-controlled trial. Am J Clin
Dermatol. 2005;6(4):245-53.
26. Kligman AM, Dogadkina D, Lavker RM. Effects of topical tretinoin on the non-sun exposed protected skin
of the elderly. J Am Acad Dermatol. 1993; 29:25–33.
27. Leyden JJ, Grossman R, Nighland M. Cumulative irritation potential of topical retinoid formulations.
J Drugs Dermatol. 2008 Aug;7(8 Suppl):s14-8.
28. Griffiths CEM, Kang S, Ellis CN, et al. Two concentrations of topical tretinoin (retinoic acid) cause similar
improvement of photoaging but different degrees of irritation. Arch Dermatol. 1995;131:1037–44.
29. Nyirady J, Bergfeld W, Ellis C, et al. Tretinoin cream 0.02% for the treatment of photodamaged facial skin:
A review of 2 double-blind clinical trials. Cutis. 2001;68:135–42.
30. Kircik LH. Safety and efficacy evaluation of tretinoin cream 0.02% for the reduction of photodamage:
a pilot study. J Drugs Dermatol. 2012 Jan;11(1):83-90.
31. Weiss JS, Shavin JS, Nighland M, Grossman R. Tretinoin microsphere gel 0.1% for photodamaged facial
skin: a placebo-controlled trial. Cutis. 2006 Dec;78(6):426-32.
1. Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging:
an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-48.
2. Manríquez JJ, Majerson Gringberg D, Nicklas Diaz C. Wrinkles. Clin Evid (Online). 2008 Dec 16;pii: 1711.
3. Kaczvinsky JR, Bertucci V, Fu JJ. Practical application of genomics to the development of a topical cosmetic
anti-aging regimen. Skin Therapy Lett. 2011 Jul-Aug;16(7):4-7.
4. Rittié L, Fisher G. UV-light-induced signal cascades and skin aging. Aging Res Rev. 2002;1:705–20.
5. Darlenski R, Surber C, Fluhr JW. Topical retinoids in the management of photodamaged skin: from theory to
evidence-based practical approach. Br J Dermatol. 2010 Dec;163(6):1157-65.
6. Kang S. The mechanism of action of topical retinoids. Cutis. 2005 Feb;75(2 Suppl):10-3; discussion 13.
7. Ogden S, Samuel M, Griffiths CE. A review of tazarotene in the treatment of photodamaged skin. Clin
Interv Aging. 2008;3(1):71-6.
8. Watson RE, Ogden S, Cotterell LF, et al. Effects of a cosmetic ‘anti-ageing’ product improves photoaged skin
[corrected]. Br J Dermatol. 2009 Aug;161(2):419-26. Epub 2009 Apr 28.
9. Singh M, Griffiths CE. The use of retinoids in the treatment of photoaging. Dermatol Ther. 2006
Sep-Oct;19(5):297-305.
10. Samuel M, Brooke RC, Hollis S, Griffiths CE. Interventions for photodamaged skin. Cochrane Database
Syst Rev. 2005 Jan 25;(1):CD001782.
11. Stratigos AJ, Katsambas AD. The role of topical retinoids in the treatment of photoaging. Drugs.
2005;65(8):1061-72.
12. Griffiths CEM, Finkel IJ, Tranfaglia MG, et al. An in-vivo experimental model for topical retinoid effects on
human skin. Br J Dermatol. 1993;29:389–99.
13. Serri R, Iorizzo M. Cosmeceuticals: focus on topical retinoids in photoaging. Clin Dermatol.
2008 Nov-Dec;26(6):633-5.
14. Kligman LH, Chen HD, Kligman AM. Topical retinoic acid enhances the repair of ultraviolet damaged
dermal connective tissue. Connect Tissue Res. 1984;12:139–50.
15. Kligman AM, Grove GL, Hirose R, et al. Topical tretinoin for photoaged skin. J Am Acad Dermatol.
1986;15:836–59.
16. Weiss JS, Ellis CN, Headington JT, et al. Topical tretinoin improves photoaged skin: a double-blind
vehicle-controlled study. JAMA. 1988;259:527–32.
17. Lever I, Kumar P, Marks R. Topical retinoic acid for treatment of solar damage. Br J Dermatol.
1990;122:91–8.
34
AGINGMATTERS
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RetinPRO™
ONLINE VOUCHER: RETIN-5-OFF-0117
Retinolic Acid
for treatment of skin wrinkles
Tretinoin 0.05% Cream, 30ml pump $34.99
(usual price $39.99)
Restrictions may apply, please see IAS terms and conditions for full details. Offer valid until 1st June 2017
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
All side effects and contraindications are available on the IAS website.
AGINGMATTERS
35
SPOTLIGHT
ESNATRI AND
PROGESTERONE
BIOIDENTICAL HORMONES
- NATURAL ESTROGENS
AND PROGESTERONE FOR
WOMEN
In this featured section we are focusing
on the use of natural estrogens and
progesterone for women, normally
utilised to aid the menopause. IAS
carries a wide range of bioidentical
hormones - a term that means ‘natural
to and in the body’.
When hormone replacement therapy
(HRT) was developed in the 1920s,
estrogens had to be derived from horse
urine because a laboratory solution was
too difficult or expensive to synthesize.
Facts pointed out by Dr. Wright in his
best-selling book ‘Stay Young & Sexy’.
Estrogens can be easily produced now.
Some people believe that the known
side-effects from ‘traditional HRT’ are
due to the fact that the hormones given
are not correct.
36
AGINGMATTERS
Introducing Esnatri
Esnatri is our bioidentical triple estrogen
cream. One of the best bioidentical
estrogen creams available. It comes
directly from the work of Dr. Wright who
has shown that the majority of women
produce estrogens in the ratios of 90%
estriol, 7% estradiol and 3% estrone.
Most tri-estrogen preparations attempt
to replicate the human hormones
estriol, estradiol and estrone, apply
them in the ratio of 80:10:10, while
some even entirely over-look estriol,
claiming it is a weak estrogen. But,
women naturally produce high levels
of estriol and it is considered to have
anticarcinogenic effects.
The Esnatri cream can be applied by
daily rotation to your neck, upper chest,
breasts and behind the knees, or inner
thighs. A typical starting dose is 2 mg.
Start from day one (of what would
have been the start of your menstrual
cycle) and continue until day 25.
You should stop for five days, before
repeating the application at the start
of the next menstrual cycle. During
these last few days, the estrogen
receptors are being allowed to ‘rest’
as they have been accustomed.
Combing Estrogen with
Progesterone
Progesterone is the counterbalance
to estrogens. Women can significantly
decline in estrogen levels during
menopause - they rarely reach
zero production levels, whereas
progesterone can sometimes not be
measured at all in elderly women. It is
also the low progesterone that most
significantly impacts bone strength,
leading onto osteoporosis. There are
numerous reasons to ensure that
progesterone is also taken alongside
an estrogen therapy. IAS provides a 5%
strength natural progesterone cream.
Typical doses are 25 mg to 30 mg of
progesterone applied on day 10 and
continuing to 25. The start date varies
according to the usual timing of your
ovulation. As with the Esnatri cream,
stop for the last five days of your cycle
so that the estrogen receptors have their
accustomed ‘rest’ period. Remember,
your hormone replacement therapy
should be overseen by a physician and
should not be undertaken if you have
undergone cancer treatment.
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SPOTLIGHT
THYROID
SUPPORT
FOR THE HYPOTHYROID
EPIDEMIC
The importance of the
thyroid gland
Dr. Broda Barnes in the 1970s estimated
that 40% of the adult population was
deficient in thyroid hormones. He
published this statement in his excellent
book - ‘Hypothyroidism, the unsuspected
epidemic.’ Since then, pupils of Dr.
Barnes, such as Dr. Richard Wilkinson,
have suggested that this figure could be
even greater now!
The hormones produced by the thyroid
control the body’s metabolism- the rate
at which it burns calories for energy. It
controls the body’s utilization of fat, so
a decline in the secretion of hormones
from the thyroid gland, (known as
hypothyroidism) can result in a range of
symptoms such as poor concentration,
confusion, memory problems, cold
hands and feet and weight gain. Another
serious condition which can be caused
by and result from an underactive
thyroid are painful musculoskeletal
issues that affect tendons, muscles
and ligaments. Your doctor can have
your blood levels of thyroid checked.
In addition to that, you can take your
body temperature when you wake in
the morning, it should be in the range of
97.8 to 98.2 degrees Fahrenheit. If it is
regularly lower you could be hypothyroid
and if higher then hyperthyroid.
The thyroid gland is of pivotal
importance to our overall health, as we
age the production of thyroid hormones
decline. This lack of thyroid function is
the root cause of a variety of age related
health disorders. Ergo, supplementation
with a synthetic or a natural thyroid can
have a significant positive effect on a
wide range of age related problems.
Choosing between synthetic
and natural thyroid
supplements
IAS stocks a comprehensive range of
both synthetic and natural thyroids,
although we advocate the use of a
natural supplement over a synthetic,
this is because products such as Armour
are of a porcine origin, so they naturally
contain the full spectrum of T1, T2, T3
and T4 thyroid hormones, (note the
bottles only list the amounts of T3 and
T4 because very few physicians are
familiar with T1 and T2).
Natural desiccated thyroids are
measured in grains; with one grain being
equivalent to approximately 60 mg. IAS
carries doses from ¼ grain to 3 grains,
with brands including Armour, ERFA and
Nature. IAS also provides synthetic T3 in
20 mcg and T4 in 100 mcg tablets.
Thyroid supplements provide potent
antiaging protection. Many aging
individuals can benefit from taking
a thyroid supplement because this
remarkable hormone has such a
profound affect across so many different
conditions. Many antiaging physicians
consider thyroid support an essential
part of any serious attempt to improve
a person’s health-span and longevity.
AGINGMATTERS
37
PEPTIDE
BIOREGULATORS
38
AGINGMATTERS
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
PEPTIDE BIOREGULATORS
PEPTIDE
BIOREGULATORS
NATURE’S GENE SWITCHES
B
ehind every great discovery, comes an
interesting story and this one is a revelation,
for it begun as a military secret, one that
has revealed a method to prolong healthy life.
This is how the ground breaking story unfolds.
THE HISTORY OF PEPTIDE
BIOREGULATORS
It all began in Russia back in the 1980s with a
Colonel, the Kremlin and a military secret! A secret
that revealed the incredible: tissue, gland and
organ specific properties of peptide bioregulators.
At the center of that secret was a Colonel from
the Soviet Union military medical corps, his name
was Vladimir Khavinson. Today, Professor Vladimir
is the President of the European Academy of
Gerontology and Geriatrics, but decades before
he had been approached by Kremlin officials who
wanted him to have the massive responsibility of
protecting their troops! So he his team tackled a
myriad of problems; there were the challenging
issues such as radiation for submariners in nuclear
submarines and troops that may be blinded by
new weapons such as battlefield lasers.
Their secret research was used for two decades
on many thousands of men and women – and it
uncovered a remarkable link between short chain
peptides and DNA.
Through a comprehensive list of patents and
copyrights, the Russian research group have
shown that each of the concentrated peptide
bioregulators so far examined, interact with
particular strands of DNA - effectively and very
specifically activating repair and regenerative
processes.
It’s no surprise that this work has seen Professor
Vladimir Khavinson nominated for the Nobel Prize
in medicine.
In this article, we want to inspire you and
encourage you to take steps that can prolong
and protect your health.
AGINGMATTERS
39
PEPTIDE BIOREGULATORS
PEPTIDE BIOREGULATORS
WHAT IS A PEPTIDE
BIOREGULATOR?
can be taken orally and doesn’t require
any suppression of the immune system
to operate fully.
A peptide is a short chain of amino
acids, identified by the fact that it is
shorter than a protein and it can be
absorbed via the digestive system. Each
organ or bodily function has its own
unique peptide bioregulator. Peptide
bioregulators have been shown to
shortcut the protein synthesis process
by interacting directly with cell DNA
– meaning that organs can build and
repair tissues easier and quicker when
peptide bioregulators are active.
Professor Khavinson and his award
winning team at the St Petersburg
Institute of Biogerontology have
discovered that each organ/gland has
a biological reserve and despite the
origin of the tissue they have studied,
incredibly each one is always set at 42%.
A peptide is a short chain of amino
acids, identified by the fact that it is
shorter than a protein and it can be
absorbed via the digestive system. Each
organ or bodily function has its own
unique peptide bioregulator. Peptide
bioregulators have been shown to
shortcut the protein synthesis process
by interacting directly with cell DNA
– meaning that organs can build and
repair tissues easier and quicker when
peptide bioregulators are active.
From our deep knowledge and years
of success stories, we are able to give
you the ability to choose to improve
your health and potentially prolong your
life. The role of peptide bioregulators
and their ability to create a protective
biological reserve for health and aging
can be simplified and explained.
This is a remarkable story since what we
are describing here are individualised
gene switches and since they have been
tested for many years on thousands
of individuals, without a report of any
serious side effects or contraindications
to date, they could be set to ‘out do’
stem cells. Why? Because this peptide
therapy is relatively cheap, highly specific,
40
AGINGMATTERS
Even dosing doesn’t need to be daily,
these peptide bioregulators have been
shown to act even after a simple course
of 2 capsules daily for 10-days. Healthy
individuals only being encouraged
to repeat the course 6-months later,
although of course depending on the
need this course can be repeated every
3-months, 2-months or 1-month if
necessary. But compared to a hormone
replacement therapy this is interesting,
since hormones would require almost
daily application. But these peptide
bioregulators aren’t hormones, they
are acting on the gland concerned to
‘encourage’ it to become active and
effectively ‘younger’ by triggering/
activating the DNA responsible.
Here at IAS we are excited about this
emerging technology and have been
following it since 2010. There’s still
more to learn including the synergistic
interaction of the peptide bioregulators
themselves and if individuals are using
hormones concurrently, then there
may well be a need to monitor their
blood levels more closely with a view to
lowering those doses and applications
etc. We will be reporting much more,
through articles, interviews and videos
etc, so please stay tuned.
As explained, each peptide bioregulator
is designed to affect a specific organ,
system or condition in the body and
uses a highly specific short chain peptide
to act as a ‘short cut’ to initiate protein
synthesis. These are some of the peptide
bioregulators listed on our site:
Bonomarlot® is the bone marrow
peptide bioregulator
Bobothyrk® is the parathyroid
peptide bioregulator
Cerluten® is the brain peptide
bioregulator
Chelohart® is the heart peptide
bioregulator
Chitomur® is the bladder peptide
bioregulator
Endoluten® is the pineal peptide
bioregulator
Glandokort® is the adrenal peptide
bioregulator
Gotratix® is the muscle peptide
bioregulator
Libidon® is the prostate gland
peptide bioregulator
Pielotax® is the kidney peptide
bioregulator
Sigumir® is the cartilage peptide
bioregulator
Suprefort® is the pancreas peptide
bioregulator
Stamakort® is the stomach mucus
peptide bioregulator
Svetinorm® is the liver peptide
bioregulator
Taxorest® is the lung peptide
bioregulator
Testoluten® is the testes peptide
bioregulator
Thyreogen® is the thyroid peptide
bioregulator
Ventfort® is the blood vessel peptide
bioregulator
Visoluten® is the retina peptide
bioregulator
Vladonix® is the thymus peptide
bioregulator
Zhenoluten® is the ovary peptide
bioregulator
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PEPTIDE BIOREGULATORS
PROFESSOR KHAVINSON’S
PEPTIDE BIOREGULATOR
RECOMMENDED
COMBINATIONS
A. Correction of disorders and maintenance of the functions
of the digestive system: Svetinorm, Suprefort, Stamakort.
B. Correction of disorders and maintenance of the functions
of the vascular system: Ventfort, Svetinorm, Vladonix.
C. Correction of disorders and maintenance of the functions
of the central nervous system: Cerluten, Ventfort, Svetinorm.
D. Correction of disorders and maintenance of the functions
of the immune system: Vladonix, Endoluten, Ventfort.
E. Correction of disorders and maintenance of the functions
of the locomotor apparatus: Sigumir, Ventfort, Vladonix.
F. Correction of disorders and maintenance of the functions
of carbohydrate metabolism: Suprefort, Endoluten, Ventfort.
G. Correction of disorders and maintenance of the functions
of lipoprotein metabolism: Svetinorm, Suprefort, Ventfort.
H. Correction of disorders and maintenance of the functions
of the functions of the thyroid gland: Thyreogen, Ventfort.
I. Correction of disorders and maintenance of the functions
of visual acuity: Visoluten, Cerluten, Ventfort.
J. Correction of disorders and maintenance of the functions
of the kidney functions: Pielotax, Ventfort.
K. Correction of organism status after radio and
chemotherapy, long-term ionizing irradiation,
psychoemotional stress and similar adverse factors:
Vladonix, Svetinorm, Endoluten.
L. Correct of cardiovascular disorders: Chelokhart, Ventfort,
Svetinorm.
Of all the peptide bioregulators, Professor Khavinson considers
‘Endoluten’ as the most effective product available for preventing
premature aging. Endoluten is a peptide bioregulator
specifically harnessed to boost and protect the function of the
pineal gland.
AGINGMATTERS
41
PEPTIDE BIOREGULATORS
THE IMPORTANCE OF THE
PINEAL GLAND
By secreting melatonin, the pineal gland plays a vital role in
ensuring the body reacts appropriately to natural rhythms
like wakefulness and drowsiness. Regular disruptions in sleep
patterns can lead to disorientation, fatigue, a lowered immune
system and depression. Many age-related illnesses feature
hormonal-imbalance as a key factor. The pineal gland is also
part of the endocrine system, which manages the balance of
hormones in the body. If this delicate balance is disrupted then
any number of attendant problems and conditions can arise.
When asked in an interview about his thoughts on peptide
bioregulators, Professor Vladimir Khavinson commented…
WHAT ARE THE BENEFITS OF
THE ENDOLUTEN® PEPTIDE
BIOREGULATOR?
The Endoluten peptide bioregulator works with the pineal
gland to help regulate melatonin and the neuro-endocrine
system. It helps normalize sleep patterns and energy levels.
This particular peptide supports libido and fights against
cancers of the reproductive glands. It serves the same role
as peptide bioregulators developed naturally in the body.
42
AGINGMATTERS
“I think it may improve everyday life of seniors, who constitute the
most vulnerable group of population. Europeans and America are
getting older and living longer than ever before, nearly 10 years
more than in 1960. Increased longevity is a great achievement
and a great challenge. It is our task to turn challenges into
opportunities and to make the most of the chances offered by
the scientific community. Peptides will bring medicine and health
systems to a new level with an accent to preventive medicine which
will help to enhance human vital resource and add life to years.”
You can read the whole interview with Professor Khavinson
here:
www.antiaging-systems.com/articles/326-the-role-of-peptide-bioregulators-interview-with-vladimir-khavinson
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
PEPTIDE BIOREGULATORS
20 x 200mg capsules
Buy any 3 and save $9.99 per box
Peptide Bioregulators, gene switches
that could replace stem cells!
Restrictions may apply, please see IAS terms and conditions for full details. Offer valid until 1st June 2017
All side effects and contraindications are available on the IAS website.
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
AGINGMATTERS
43
SPOTLIGHT
YOUTH GEMS
THE PEPTIDE
BIROREGULATORS FOR SKIN
Four peptide bioregulators have
now been combined into topical skin
preparations so that their unique
gene-switching performance can be
bought to the field of aesthetic medicine.
What does each peptide
provide for?
The beauty product line Youth Gems
contains the following four peptides and
a ginseng extract called Neovitin. The
latest developed program of complex
skin care designed for the face, neck,
hands and the body.
The line includes four unique active
ingredients of short-chain peptides that
have a directed tissue-specific action to
improve all basic skin structures:
• Thymus peptide: Stimulates tissue
regeneration and synthesis of
tissue-specific proteins. Cells
proliferative and metabolic activity is
enhanced accelerating the renewal of
cell tissues. Has an anti-inflammatory
action, improving healing time of
wounds, as well as antioxidant, immune
stimulating and anti-stress actions.
• Pineal peptide: Regulates metabolic
processes and increases protein
synthesis in skin cells. It possesses
potent antioxidant activity, normalizes
the lipid peroxidation processes in skin
44
AGINGMATTERS
cells that promotes the elimination of
negative influences on the skin from
external factors.
• Cartilaginous peptide: Stimulates
regeneration of fibroblasts and
keratinocytes and interferes with the
destructive changes in collagen skin
structure. It strengthens collagen
structure of elastic skin fibres and
increases elasticity.
• Blood vessel peptide: Regulates
metabolic processes in the
vascular wall, normalizes vascular
tone and restores disturbed skin
microcirculation. It strengthens and
regulates the permeability of the
vascular walls of skin vessels and
improves skin turgor.
Youth Gems contain beneficial natural
agents. The range includes: Neovitin
(a complex from ginseng), olive oil,
raisin-seed oil, Argon oil, Soya oil, Jojoba
oil, Bisabolol ( from chamomile), Peony
extract, sodium hyaluronate (derivative
of hyaluronic acid), green tea extract,
cocoa oil, carrageenan (from seaweed),
winter bloom, almond extract and
vitamin E.
What results have been
seen?
Clinical trials and examinations have
been conducted at the St. Petersburg
Biogerontology Institute. They concluded
that these short chain peptides have
many beneficial activities.
Improved metabolism in vascular wall
cells, growth of new skin cells, enhanced
antioxidant activity, increased blood flow
circulation and greater moisturization.
The skin’s appearance becomes
smoother, fewer wrinkles and more
elasticity, which helps to lift the face
contours producing a more radiant,
youthful appearance. These beneficial
effects were noted in 100% of women
who took part in the voluntary clinical trial.
What’s available?
Body milk: A very light cream that can
be applied to most areas of the body.
Day cream: A core product designed to
be applied to the face and hands.
Serum: To be used sparingly against the
most noticeable skin aging effects on the
face and neck.
Tonic: Used to help any area become
more firm and taught and may be
splashed on as required.
Face pack: An anti-aging facial mask with
peptides and ginseng extract.
Night cream: This unique formula
provides resilience against skin aging.
All of the Youth Gems products should
be applied onto clean, dry skin - avoiding
the eyes. Makeup can be applied after
absorption - if required.
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
SPOTLIGHT
GHRPs
A REAL ‘ORAL’ ALTERNATIVE
TO GH INJECTIONS
Since Dr. Rudman’s research work in the
1980s and the release of Dr. Klatz’s book
‘grow young with HGH’ in the 1990s,
there has been great interest in the use
of growth hormone (GH) in antiaging
medicine. Dr. Rudman concluded,
having injected elderly patients with
GH, many had reversals of biological
age markers by as much as 20-years.
Improved skin, hair, muscle mass,
decreased fat levels and enhanced
levels of stamina, strength and
well-being. It’s not surprising given the
multi-faceted role of growth hormone
and as its name suggests it is involved
in the growth and repair of tissues.
GH injections
The issue with injecting GH, other than
expense, is it has to be injected to be
effective because as a 191 chain amino
acid it can’t be absorbed another way.
GH injections can be classified as a
controlled substance, due to its anabolic
actions. They could require special
import and export licenses.
Dr. Richard Walker researched and
highlighted that bolus injections of GH
are not bio-identical and they induce
spikes of GH into the blood so could
damage the pituitary gland, leading to
a down-regulation of its production of
GH, or stop GH production altogether.
Dr. Walker’s research shows using
GHRPs (growth hormone releasing
peptides) have a safer profile with
the same benefits.
Read this article in the Aging Matters™
magazine, No:3, 2014 to understand more.
GHRPs (growth hormone
releasing peptides)
GHRPs, (GHRP2, GHRP6 and sermorelin)
have these benefits:
They can be sublingually,
intra-nasally and even orally,
avoiding the need for needles
Their feedback loop means they
cannot cause the pituitary to
down-regulate
GHRPs are not controlled substances
Rather than inducing a spike of GH
in the blood, GHRPs augment
(improve) each release of GH
naturally into the blood
eliciting up to a 5x greater quantity of
GH into blood, an action that can be
equivocated to using injectable GH itself.
Note: You can hear Dr. Walker discuss
this with us on the IAS video page:
www.youtube.com/watch?v=S5OlEhbM7lQ
The differences:
GHRP6 may induce more hunger
feelings than GHRP2 and could
improve levels of IGF-1 more.
Recommended for those who want
to put on muscle mass
GHRP2 may create fewer hunger
feelings. Preferable to those who
want to stimulate GH for fat loss.
Also as the GHRP6 (Release-Pro™)
is a nasal spray, those who don’t like
that may prefer GHRP2-Pro™ which
can be swallowed
GHRPs have created a genuine
efficacious alternative; simple and easier
to use. They have a better/ safer profile
than injectable GH.
Sermorelin is the precursor to GH, being
the first 29 amino acids and is applied via
the sublingual route. Its function may be
to release existing stores of GH from the
pituitary- rather than encourage more
production as a pure agonist would.
Dr. Walker highlighted that combining
sermorelin with GHRP2 or GHRP6 has a
highly synergistic effect, in some cases
AGINGMATTERS
45
SPOTLIGHT
OXYTOCIN
FOR PASSION AND SEX
The love hormone
The effects of Oxytocin
Oxytocin is a hormone produced by the
hypothalamus, excreted via the pituitary
gland. Its orthodox medicine role is to
help women give birth, since the large
dose that’s injected helps relaxes the
uterus and alleviates the passage of
the child. Dr. Thierry Hertoghe’s book,
‘Passion, sex and longevity, the oxytocin
adventure’ highlights that it has many
other roles too.
Oxytocin has been dubbed ‘the love
hormone’. It can induce feelings of
bonding and care. Its measurements
have been taken between lovers, friends,
relatives, parents and their children
etc. It has been noted that oxytocin
levels are higher when they are in their
presence. Mothers naturally bond with
their children, but even men, (especially
those who experience the live birth),
express their emotions as wanting to
care and protect their off spring. These
effects may be attributable to the release
of oxytocin hence triggering the bond.
However, psychopaths are notoriously
low in their oxytocin levels, which may
be a cause of their uncaring feelings
towards other humans.
Dr. Hertoghe explained that some will
not feel the effects of Oxytocin. For two
reasons, (if we consider that the dose
is correct for that individual). Firstly,
some people are ‘low’ in their own
principal sex hormone, so if a man is
low testosterone, or if a woman is low
estrogen, it is possible that oxytocin
will not elicit its full potential in those
persons. The other issue could be
low vasopressin, vasopressin is a
counterpart to oxytocin, produced and
released via the same glands. In cases
of vasopressin deficiency, the patient
may enhance the oxytocin experience by
adding one or two sprays (10 IU each) of
vasopressin via the Vaso-Pro nasal spray.
The pain and orgasm connection Fibromyalgia can be a very debilitating
disorder with a lot of pain, sometimes
constant for those who suffer with it.
In women, it was noted that when they
were experiencing an orgasm they
felt no pain at all. Women undergo a
burst of oxytocin during orgasm. Trials
were undertaken to see if oxytocin
supplementation could alleviate the pain
of fibromyalgia, there was some success,
but the side-effect noted was that those
women now enjoyed multiple orgasms!
46
AGINGMATTERS
Doses are very dependent upon its use.
For social or sexual enhancement, 5 IU
to 10 IU is a ‘typical’ dose. Dr. Hertoghe
reduced the doses that he recommends
in his book, (transmitted via personal
conversation to me). Currently, IAS is
providing Oxy-Sub in 20 IU trouches
(a soft sublingual tablet). These can be
cut into half or quarter for a dose of 5
or 10 IU and should be placed under
the tongue and allowed to melt. The
other option is Oxy-Pro which is applied
intranasally delivering 10 IU per spray.
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SPOTLIGHT
BIOCLIP®
CUFF
MONITORING YOUR
VASCULAR CONDITION
The BioClip® Cuff is a simple way of
assessing both your blood pressure
condition and your arterial flexibility.
You can use it in the comfort of your
own home. You simply attach the device
to your arm just like an ordinary blood
pressure cuff.
What does the BioClip® Cuff
measure?
It provides a series of metabolic
indicators that you can use to improve
your lifestyle and help prevent the
causes of cardiovascular disease
These include:
• Diastolic blood pressure
• Systolic blood pressure
• The heart rate
• Vascular condition – which links
to arterial flexibility
We know the risks of being overweight,
having high cholesterol or suffering
from high blood pressure. We know how
to reduce those risks – exercising, not
smoking, reducing alcohol intake and
eating a balanced diet. Few of us know
about the dangers of arterial inflexibility,
or how to measure it. BioClip® Cuff
is unique, the first at-home device able
of delivering information to you within
minutes. It evaluates your arterial
flexibility, a most important factor when
it comes to assessing the likelihood of
a heart attack or stroke. Arteries are
responsible for blood flow around your
body via your cardiovascular system.
The poorer your vascular condition,
the greater your chances of serious
health issues. Our arteries stiffen with
age, bringing greater risk of a heart
attack, heart failure or stroke. You may
not recognise the symptoms, arterial
stiffness can occur without warning.
Summary:
The BioClip® Cuff provides a
cardiovascular condition scale, shown
by LED bars - that are either within the
green zone (good), yellow zone (fair) or
red zone (poor). Like blood pressure,
vascular condition should be monitored
over time and not just taken as one
reading. The BioClip® Cuff makes this
simple by averaging your tests over time
and therefore provides a more accurate
result. It provides reassurance and a vital
early warning system that helps you be
aware of changes and therefore keep
your vascular condition in check.
The BioClip® Cuff is easy to use.
It doesn’t puncture your skin and is
used on its own, without any additional
attachments. The procedure is
straightforward and you don’t need to
link to a computer, the results are
shown on the BioClip® Cuff screen.
If you want to see it in action there is a
video available on the IAS website. With
this information, it’s easy to keep a check
on your cardiovascular health and the
risks associated with arterial stiffness,
such as heart attacks and strokes.
It is possible to make changes to your
lifestyle and supplement program to
improve results and keep you biologically
younger! Above all, the BioClip® Cuff
provides reassurance and a vital early
warning system that helps you to be
aware of changes and therefore keep
your vascular condition in check.
AGINGMATTERS
47
CROSS-REFERENCE
CONDITION CROSS-REFERENCE LIST
This cross-reference list highlights individual products that have been used
for these disorders.
Note: It does not mean that all these products are synergistic together.
Addison’s disease Aldosterone, peptide bioregulator (adrenal)
ADHD (ADD, attention deficit disorder, see mental stimulants)
Adrenal fatigue Aldosterone, hydrocortisone, peptide
bioregulator (adrenal)
AGE (advanced glycated end-product inhibitors)
ACF228™, aminoguanidine, Can-C™ Plus, carnosine, metformin
Age Related Macular Degeneration (see eyesight)
Age Related Mental Decline (see cognitive)
Antiaging (as impacting on a particular theory of aging)
Calorie Restriction Carnosine, metformin, resveratrol
Free radical ACF228™
Glycation Aminoguanidine
Hayflick Carnosine, Peptide Bioregulator (pineal),
TA65®
Membrane Centrophenoxine
Mitochondrial HyPro2™, PQQ
Neuroendocrine Metformin, TRH
Rotational Melatonin
Telomeres Peptide biomarker (pineal), TA65®
Anti-biotics Ciproflaxin, doxycycline, roxithromycin,
tetracycline
Aids (see HIV)
Alcoholism (also see compulsive disorders)
5HTP, L-tryptophan, memantine
Allergies Pregnenolone, thymus
ALS (amyotrophic lateral sclerosis, Lou Gehrig’s disease)
Naltrexone, TRH
Anti-depressants Lithium, milnacipran (Ixel®),
reboxetine (Edronax®), Stablon®, Valdoxan®,
venlafaxine (Efexor®)
Anti-oxidants (see free radical scavengers)
Anxiety (see stress)
Alzheimer’s disease (see senile dementia)
ARMD (see eyesight)
Anabolic (see growth hormone & testosterone)
Arterial (See heart, arterial & blood)
Anginas (see heart, arterial & blood)
Arthritis (rheumatoid & osteo) Andro-Pro™,
Gerovital-H3®, Novisyn®, PEO pregnenolone,
SAMe, thymus,
Animal use Can-C™ eye-drops, deprenyl, L-tryptophan,
peptide bioregulators (all)
Asthma (see Allergies)
48
AGINGMATTERS
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CROSS-REFERENCE
Autism (also see chelation agents) Oxytocin, piracetam
Cross linking (see AGE)
Back problems (see spine)
Deep vein thrombosis (see frequent fliers)
Bell’s palsy Vitamin B12
Dental (see teeth & gums)
Blood disorders (see heart, arterial & blood)
Depression (also see well-being & anti-depressants)
5HTP, aniracetam, ATP-Boost™, curcumin, deprenyl,
Gerovital-H3®, lithium, L-tryptophan, milnacipran,
picamilone, piracetam, pramiracetam, pregnenolone,
SAMe, thymus, thyroid
Blood pressure Magnesium, Neo40®, oxytocin, potassium,
propranolol, vinpocetine
Bone problems (also see joints & arthritis) Andro-Pro™, BonePro2™, Esnatri™, peptide bioregulator (Bone), progesterone,
SAMe, thyroid
Breathing (see lungs)
Cancer (also see anti-oxidants & radiation) 1st Line™,
anastrozole, BEC5® Curaderm, bromocriptine, curcumin,
DIM-Pro2™, laetrile, melatonin, metformin, naltrexone,
oxaloacetate, progesterone, resveratrol, thymus, TRH
Cardiovascular (see heart & arterial disorders)
Cataplexy (sudden fatigue) Adrafinil, picamilone
Cataract (see eyesight)
Central Nervous System (CNS) Peptide bioregulator (brain)
Peptide bioregulator (Cerluten®)
Chelation agents Carnosine, centrophenoxine, DMSA, EDTA,
zeolite
Cholesterol (see blood disorders)
Crohn’s disease Naltrexone
DHT alternation (dihydrotestosterone) Dutasteride,
finasteride, peptide bioregulator (prostate), progesterone
Diabetes Acarbose, aminoguanidine, ATP-Boost™,
benfotiamine, L-carnosine, metformin, Mito-Pro2™, PEO,
peptide bioregulator (pancreas), pyridoxamine, thyroid, TRH
Diabetes insipidus (see urination)
Dieting (see weight loss)
Digestive issues peptide bioregulator (Stomach), Symprove®
DNA support (also see telomeres) Carnosine, CoQ10, PEO,
peptide bioregulator (pineal), PQQ, resveratrol, TA65®
Down’s syndrome Melatonin, piracetam
Energy improvement (see physical energy & mental
stimulants)
Enzymes Boluoke®
Epilepsy GABOB, phenytoin
Chronic fatigue syndrome (see mental stimulants & physical
energy improvement)
Erectile dysfunction (also see sex-libido & premature
ejaculation) Andro-Pro™, cabergoline, deprenyl, Neo40®,
oxytocin, sildenafil, Vielight®, VigorPro2™
Cognitive (also see memory & senile dementias)
Eyesight
Alertness Adrafinil, Xan-Pro™
Creativity Aniracetam, piracetam, pramiracetam
Focus/ concentration Deprenyl, desmopressin, vasopressin
Energy ATP-Boost™, centrophenoxine, Mito-Pro2™, NADH,
picamilone
General support Gerovital-H3®, vinpocetine
Intelligence HyPro2™
Work load HyPro2™, thyroid
Compulsive disorder treatment (also see alcoholism)
5HTP, GABOB, L-tryptophan, picamilone
Cortisol alteration (also see stress) Aldosterone, DHEA,
GABOB, Gerovital-H3®, hydrocortisone, peptide bioregulator
(adrenal), phenytoin
ARMD MZS™
Cataracts Can-C™, Can-C™ Plus
Contact lenses Can-C™
Dry eyes Can-C™
General support Aminoguanidine, peptide bioregulator
(retina), vinpocetine
Glaucoma Can-C™
Retinal MZS™, picamilone
Retinal pigmentosa Picamilone, peptide bioregulator (retina)
Excitotoxins (reduction) Carnosine, deprenyl, idebenone,
lithium, memantine
Fertility Melatonin, metformin, peptide bioregulator
(ovaries), TRH
AGINGMATTERS
49
CROSS-REFERENCE
Fibromyalgia (also see physical energy & mental stimulants &
pain relief) 1st Line™, milnacipran, naltrexone, oxytocin
Free radical scavengers ACF228™, ATP-Boost™, BHT,
glutathione, idebenone, melatonin, Mito-Pro2™
Gastrointestinal (see digestive)
Herpes (also see anti-biotics) 1st Line™, ACF228™, BHT, silver
HIV (also see immune system improvement) 1st Line™,
melatonin, naltrexone, thymus
HCG (see HCG-Pro™)
HGH (see growth hormone)
Glaucoma (see eyesight)
Homocysteine (see heart, arterial and blood)
Glucose control (see diabetes)
Glycation prevention (see AGE)
HRT (hormone replacement therapy for women) DHEA,
Esnatri™, melatonin, progesterone
Gout Colchicine
Human growth hormone (see growth hormone)
Growth hormone (improvement) Bromocriptine, deprenyl,
GABOB, GHRP2, GHRP6, HyPro2™, IGF-1, Neo40®, sermorelin,
thymus, thyroid
Hypertension (see blood pressure)
Hashimoto’s Iodine, peptide bioregulator (Thyroid), thyroid
IBS (irritable bowel syndrome) Symprove®
Hair improvement Dercos®, dutasteride, finasteride,
Gerovital-H3®, MinMaxPro™, PEO
Immune system improvement (also see infections) 1st
Line™, ATP-Boost™, beta-glucans, carnosine, melatonin,
peptide bioregulator (thymus), peptide bioregulator (thyroid),
resveratrol, thymus, thyroid
Headaches (see migraines)
Health diagnostics (see at home test kits)
Hearing disorders Aldosterone, picamilone, vinpocetine
Heart, arterial & blood (includes blood markers)
Arteries (hard) Aminoguanidine, BioClip® Cuff, carnosine,
resveratrol
Blood pressure (high) Magnesium, Neo40®, potassium,
propranolol, vinpocetine
Calcium Peptide bioregulator (parathyroid)
Cholesterol (high) CoQ10, Gerovital-H3®, MitoQ®, TRH,
Xan-Pro™
Dilation (nitric-oxide) Deprenyl, Neo40®, Vielight®
Fibrinogen Curcumin, TRH
General support CoQ10, PEO, peptide bioregulators (heart
and blood vessel), PQQ, vinpocetine
Glucose (high) Acarbose, metformin, TRH
Glycated end-products ACF228®, aminoguanidine,
metformin
Heart pulse (irregular) ATP-Boost™, thyroid
Heavy metals (chelate) DMSA, EDTA, zeolite
Homocysteine TRH
Lipofuscin Centrophenoxine
Plaques (clots) Boluoke®
Triglycerides Curcumin, PEO, TRH
Hepatitis (see liver and infections)
50
AGINGMATTERS
Hypothyroidism Iodine, peptide bioregulator (thyroid), thyroid
Infections (also see immune system improvement, anti-biotics
& influenzas) 1st Line™, beta-glucans, fluconazole, silver
Inflammation (reduction) Boluoke®, curcumin, PEO,
pregnenolone, thymus
Influenzas (also see anti-biotics, infections & immune system
improvement) 1st Line™, beta-glucans, vitamin D3
Injectable products Gerovital®, IGF-1, vitamin B12
Insulin & glucose control (see diabetes)
Intestinal flora (see probiotics)
Intra-ear products Aldo-Spray™
Intra-nasal products Desmopressin, GHRP6, HCGPro™,
vasopressin, Vielight®
Joints (also see bones & arthritis) Boluoke®, Novisyn®, PEO,
peptide bioregulator (cartilage), pregnenolone, SAMe, thymus
Kidney disorders (also see infections) Aminoguanidine,
peptide bioregulator (kidney) SAMe, TRH
Learning (also see memory & mental stimulants) Aniracetam,
desmopressin, HyPro2™, piracetam, pramiracetam,
vasopressin
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
CROSS-REFERENCE
Libido (see sex)
Lipids (see blood disorders)
Liver disorders (also see infections) CoQ10, idebenone,
peptide bioregulator (liver), pregnenolone, SAMe, silver
Longevity enhancement (significant lifespan increases seen
in animal studies) Centrophenoxine, deprenyl, melatonin,
peptide bioregulator (pineal) vasopressin
NAD+ activators NAD+Pro™
Nail condition Gerovital-H3®, PEO
Narcolepsy (sleeping in the daytime) Adrafinil, melatonin,
picamilone
Nitric Oxide release Neo40®, Nitric Oxide saliva test strips,
Vielight®
Lou Gehrig’s disease (see ALS)
Oral health care (see teeth & gums)
Lungs ACF228™ Breathe-Easy, centrophenoxine, glutathione,
peptide bioregulator (lungs)
Osteoporosis (see bone problems)
Lupus Milnacipran, naltrexone
Pain relief (general) ATP-Boost™, Gerovital-H3®, memantine,
milnacipran, oxytocin
Lyme’s 1st Line™, beta-glucans, silver
Parasites (see infections)
Macular degeneration (see eyesight)
Parkinson’s disease (see senile dementia)
Malaria (see anti-biotics)
Pets (see animal use)
Menopause (see HRT)
Photoaging (see skin problems)
Mental stimulants (also see physical stimulants) Adrafinil,
aniracetam, centrophenoxine, deprenyl, desmopressin,
picamilone, piracetam, pramiracetam, vasopressin, Xan-Pro™
Ph balance (rebalancing) Symprove®
Memory (also see cognitive & senile dementia)
General support PEO, picamilone, vinpocetine
Imprinting (for later recall) Desmopressin, vasopressin
Medium-long term HyPro2™
Short term Aniracetam, piracetam, pramiracetam
Speed of recall Centrophenoxine
Methylation (conversion of one chemical into another inside
the body) ATP-Boost™, Boluoke®, Mito-Pro2™, SAMe, Xan-Pro™
Migraines (also see pain relief) Nicergoline, memantine,
picamilone, vitamin B12
Physical energy improvement (also see mental stimulants)
ATP-Boost™, carnosine, CoQ10, idebenone, MitoQ™, NADH,
oxaloacetate, PQQ, pregnenolone, SAMe
PMS (pre-menstrual syndrome) PEO, peptide bioregulator
(ovaries), vinpocetine
Premature ejaculation/ ejaculate (also see erectile
dysfunction & sex-libido) Oxytocin
Probiotics Symprove®
Prostate (also see cancer) DIM-Pro2™, dutasteride, finasteride,
melatonin, peptide bioregulators (bladder and prostate),
Prostate-Pro2™
Mitochondrial support ATP-Boost™, CoQ10, deprenyl,
glutathione, HyPro2™, idebenone, MitoQ™, NADH,
oxaloacetate, PQQ, pregnenolone, SAMe
Prolactin alteration Bromocriptine, cabergoline, GABOB
Mtor inhibitors Curcumin, oxaloacetate, resveratrol
Urination (frequent) Peptide bioregulator (bladder),
vasopressin
Multiple Sclerosis (also see mitochondrial support) Melatonin,
naltrexone, TRH
Muscles (see sarcopenia)
PSA (prostate specific antigen- see prostate)
RNA (see DNA support)
Sarcopenia (muscle atrophy/ wastage) GHRP2, GHRP6,
peptide bioregulator (muscle), sermorelin
AGINGMATTERS
51
CROSS-REFERENCE
Senile dementia (also see cognitive & memory)
Alzheimer’s Centrophenoxine, curcumin, galantamine,
HyPro2™, memantine, nicergoline
General support aniracetam, PEO, piracetam, pramiracetam,
vinpocetine
Parkinson’s Bromocriptine, cabergoline, deprenyl, NADH,
memantine, rasagiline
Stomach (see digestive)
Sublingual products Oxytocin, sermorelin, TRH
Sunburn (see skin problems)
Syndrome X (metabolic syndrome) Aminoguanidine,
ATP-Boost™, melatonin, metformin, Mito-Pro2™, PEO
Senility Gerovital-H3®
Tanning (darkening the coloration of skin) MSH2
Sex (libido, also see erectile dysfunction & premature
ejaculation) Andro-Pro™, deprenyl, MSH2, oxytocin, VigorPro2™
Teeth & gum disorders Doxycycline, Min-Mouth™
mouthwash, NeyDent® toothpaste, silver, zeolite
Skin problems (also see herpes and tanning)
Telomeres (also see DNA support) Carnosine, PEO, peptide
bioregulator (pineal), TA65®
Acne Beta-glucans
Age (liver) spots Centrophenoxine, Youth Gems® face mask
Anti-glycation Aminoguanidine, carnosine, Youth Gems®
serum
Anti-oxidant Youth Gems® day cream and night cream
Cancer (non-melanoma) BEC5® Curaderm
Cellulite Youth Gems® body milk
Collagen Novisyn®
Environmental Youth Gems® serum and face mask
General support Gerovital-H3®, melatonin, PEO, thyroid
Infections Silver, thymus
Moisturizer Youth Gems® day cream and night cream
Psoriasis Beta-glucans
Scars RetinPro™
Sun spots (keratosis) BEC5® Curaderm
Wounds Silver
Wrinkles RetinPro™
Sleep disorders
For less sleep Adrafinil, ATP-Boost™
For more sleep 5HTP, gabapentin, L-tryptophan, melatonin
Smoking cessation 5HTP
Testosterone & testes (also see fertility and prostate)
Anastrozole, Andro-Pro™, DIM-Pro2™, melatonin, oxytocin,
peptide bioregulator (testes), TRH, VigorPro2™, zinc
Topical products BEC5®, beta-glucans, Can-C™ eye-drops,
Esnatri™, progesterone, RetinPro™, silver, Youth Gems®
Triglycerides (see blood disorders)
Veterinarian (see animal use)
Weight gain (muscle mass) Andro-Pro™, GABOB, GHRP6,
sermorelin
Weight loss (appetite suppressants and fat burners) 5HTP,
acarbose, aminoguanidine, ATP-Boost™, DHEA, DIM-Pro2™,
galantamine, GHRP2, HCG, L-tryptophan, metformin,
Mito-Pro2™, MSH2, thyroid, TRH, Xan-Pro™
Well-being (also see depression) 5HTP, aniracetam,
ATP-Boost™, deprenyl, GABA, Gerovital-H3®, L-tryptophan,
melatonin, Mito-Pro2™, PEO, picamilone, piracetam,
pramiracetam, SAMe, thymus, thyroid, zeolite
Spine issues (also see growth hormone) Novisyn®, peptide
bioregulator (cartilage)
Sports (see growth hormone, estrogen alteration, physical
energy & testosterone)
Stem Cells Stem Cell Worx®
Stress (also see cortisol) 5HTP, GABA, Gerovital-H3®,
L-tryptophan, melatonin, oxytocin, picamilone, phenytoin,
pregnenolone, propranolol
Stroke Aniracetam, Boluoke®, HyPro2™, idebenone, PEO,
picamilone, piracetam, PQQ, pramiracetam, pregnenolone,
vinpocetine
52
AGINGMATTERS
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
A-Z INGREDIENT LIST
A-Z INGREDIENT LIST
The following list is intended to highlight the key ingredients in some products and cross
reference them to the most relevant product brand names.
Note: Those products with the same name as the ingredients are not shown here as they are within the A-Z product list.
If you want this-
Look for:
5-hydroxy-tryptophan
5HTP
Acetyl-L-Carnitine (ALC)
ATP-Boost™, Vigor-Pro2™
Adenosine triphosphate
(ATP)
ATP-Boost™
Aglomelatine
Beta alistine
Carnosine, ACF228™,
Can-C™, Can-C Plus™
Beta glucan
BG-Cream™, BG-Pro™
bFGF
Hair-Pro™
BHT (butylhydroxytoluene)
ACF228™, BHT-Pro™
Valdoxan®
Blueberry extracts
Andro-Pro™
Allicin (garlic)
EDTA-Pro™
Borate
Andro-Pro™, Can-C™
Alpha lipoic acid
(R-lipoic acid)
ATP-Boost™, Mito-Pro2™
Boron
Andro-Pro™
Aminexil
Dercos®
Buxamin (GABOB)
Gamibetal®
Amino acids (includes
di-peptides
5HTP, ACF228™, ATPBoost™, carnosine,
L-tryptophan, Mito-Pro2™
Caffeine
Minox-Pro™
Calcium
Bone-Pro2™
Aminohydroxybutyric acid
(GABOB)
Gamibetal®
Carboxymethylcellulose
Can-C™
Catalase
ACF228™
Aminosyn
Hair-Pro™
Chelation agents
Anti-biotics
Ciproxin, doxycycline,
penicillin, roxithromycin,
tetracycline
Carnosine,
centrophenoxine, DMSA,
EDTA-Pro™, zeolite
Choline
Centrophenoxine
Chromium polynicotinate
ACF228™
Citrulline
Neo40®
Co-dergocrine mesilate
Hydergine®
Coenzyme Q10
CoQ10, Mito-Pro2™
Colloidal Silver
Silver
Colostrum
Stem Cell Worx®
Cortisol (cortisone)
Fludrocortisone,
hydrocortisone
Anti-depressants
Lithium, milnacipran,
moclobemide, reboxetine,
Stablon®, Valdoxan®,
venlafaxine
Anti-oxidants
See free radical scavengers,
Arginine
Mito-Pro2™
Arimidex®
Anastrozole
Astragalus extracts
TA65
Azelaic acid
Minox-Pro™
Azilect®
Rasagiline
Cranberry extracts
Andro-Pro™
Benzoic acid
Gerovital®
Creatine
Mito-Pro2™
Beta blocker
Propranolol
Cresote bush
ACF228™
®
AGINGMATTERS
53
A-Z INGREDIENT LIST
If you want this-
Look for:
Florinef®
Fludrocortisone
Cycloastragenol
TA65®
Folic acid (folate)
ACF228™, DIM-Pro2™
Cyclodextrin
CoQ10-SR™, Curcumin-SR™,
resveratrol
Free radical scavengers
Dehydroepiandrosterone
DHEA
ACF228™, ATP-Boost™, BHT,
glutathione, idebenone,
melatonin, Mito-Pro2™,
pyritinol
Detox
DIM-Pro2™, EDTA-Pro™,
zeolite
Fructoborate
Andro-Pro™
Fucoidan
Stem Cell Worx®
GABA (gammaaminohydroxybutyric acid)
picamilone
GABOB
Gamibetal®
GHRP6
Release-Pro™
Ginseng
Youth Gems®
Glucophage®
Metformin
Glutathione
ACF228™, ACG
Glycerine (glycerin)
Can-C™
Glycosides
BEC5 Curaderm®
Hawthorne Berry
(crataegus)
Neo40®
DHA
(docosahexaenoic acid)
PEO-Pro™
Diapid®
Vasopressin
Di-IndolylMethane (DIM)
ACF228™, DIM-Pro2™
Dilantin®
Phenytoin
DMAE
(dimethylaminoethanol)
Centrophenoxine
DMSA
(dimercaptosuccinic acid)
ACF228™, DMSA-Pro™
D-pantethine
Can-C Plus™
Dr. Dean’s
recommendations
Acarbose, centrophenoxine,
CurcuminSR™, Hydergine®,
metformin, piracetam,
Xan-Pro™
Dr. Pierpaoli’s
recommendations
Melatonin, TRH
HGH (human growth
hormone/somatropin)
GABOB, GHRP2, GHRP6,
sermorelin
Dr. Wright’s
recommendations
DHEA, Esnatri™,
progesterone
Hormones (includes
hormonal support
supplements)
Ebixa®
Memantine
Bio-identical: Aldosterone,
DHEA, Esnatri™, melatonin,
MSH, oxytocin, pregnenolone,
progesterone, TRH
EDTA (ethylene diamine
tetraacetic acid)
EDTA-Pro™
Eldepryl®
Deprenyl
Electrolytes
Volt-Pro™
Enzymes
Boluoke®
EPA (eicosapentaenoic
acid)
PEO-Pro™
Ergoloid mesylate
Hydergine®, nicergoline
Estrogens (estradiol,
estriol, estrone)
Esnatri™
Finasteride
Hair-Pro™
54
AGINGMATTERS
Natural (animal): Armour®
thyroid, ERFA® thyroid,
Nature® thyroid, thymus,
vasopressin
Synthetic: Desmopressin,
Eutirox® thyroid,
fludrocortisone,
hydrocortisone, T3-Pro™
Supporting agents:
DIM-Pro2™, GHRP2, GHRP6,
peptide bioregulators,
SAMe, sermorelin
HRT (hormone
replacement therapy for
women)
DHEA, Esnatri™, melatonin,
progesterone
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
A-Z INGREDIENT LIST
Hyaluronic acid
(hyaluronan)
Hair-Pro™, Novisyn®
Hydergine (ergoloid
mesylates)
Hy-Pro™
IGF-1 (insulin like growth
factor one)
N-acetylcysteine
ACF228™, Can-C™ Plus
Namenda®
Memantine
Neurontin®
Gabapentin
IGF-1 (LR3)
Nettle root extract
Prostate-Pro2™
Indol-3-Carbinol (I3C)
DIM
Niacin (nicotinate,
niacinamide, vitamin B3)
Picamilone, Xan-Pro™
Iodide/ Iodine
ACF228™, Iodine-Pro™
NADH, PQQ
Ixel®
Milnacipran
Nicotinamide adenine
dinucleotide
Ketoconazole
Nizoral®
Nootropil®/ Nootropyl®
Piracetam
L-arginine
Mito-Pro2™
Nordihydroguaiaretic acid
(NDGA)
ACF228™
L-carnitine
Mito-Pro2™
Omega 3 (DHA)
PEO-Pro™
L-carnosine
Carnosine, ACF228™,
Can-C™, Can-C Plus™
Omega 6 (linoleic acid,GLA)
PEO-Pro™
L-citrulline
Neo40®
Omega 9 (oleic acid)
PEO-Pro™
L-histidine
Can-C Plus™
Oxythiocynate (OCSN)
1st Line™
Lipoic acid (includes
R-lipoic acid)
ATP-Boost™, Mito-Pro2™
Parent Essential Oils (PEO)
PEO-Pro™
Gerovital®
L-methione
ACF228™, Can-C Plus™
PABA (para-aminobenzoic
acid)
Lucidril®
Centrophenoxine
Panthenol (pantothenic
acid)
Mito-Pro2™
Lumbrokinase
Boluoke®
Centrophenoxine
Magnesium
Andro-Pro™, Bone-Pro2™,
Magnesium-Pro™,
Mito-Pro2™
PCPA (paarachlorophenoxyacetic acid)
Pepermint Oil
Min-Mouth™ mouth rinse
Malic Acid
EDTA-Pro™
Peptides
Manganese
Mito-Pro2™
GHRP2, GHRP6, peptide
bioregulators, sermorelin,
TRH, Youth Gems®
Meclofenoxane
Centrophenoxine
Pimagedine
Aminoguanidine
Melanocyte stimulating
hormone
MSH2
Pomegranate extracts
Andro-Pro™
Potassium
Gerovital®, Potassium-Pro™
Mild Silver Protein
Silver
Prasterone
DHEA
Milk protein
Bone-Pro2™
Propionyl-L-carnitine
Vigor-Pro2™
Minerals (general)
Min-Mouth™ (mouthwash),
Volt-Pro™
Probiotics
Symprove®
Procaine (Novocain®)
Gerovital®
Pygeum africanum
Prostate-Pro2™
Minoxidil
MinMax-Pro™
N-acetylcarnosine
Can-C™
AGINGMATTERS
55
A-Z INGREDIENT LIST
If you want this-
Look for:
VEGF
Hair-Pro™
Pyroloquinoline quinone
PQQ
Vincamine
Anacervix®
Red clover herb extracts
Prostate-Pro2™
Vinpocetine
Vin-Pro™
Reminyl®
Galantamine
Vitamin B1 (thiamine)
Mito-Pro2™
Resveratrol
Resveratrol-SR™,
StemCell Worx®
Vitamin B2 (riboflavin)
Mito-Pro2™
Retinolic acid (tretinoin)
Retirides®
Vitamin B3 (niacin,
niacinamide)
Mito-Pro2™, Picamilone,
Xan-Pro™
Ribonucleic acids (RNA)
NeyDent® toothpaste
Salicylic acid
BEC5 Curaderm®,
Sol Answer™
Vitamin B6 (pyridoxal,
pyridoxine)
ACF228™, Andro-Pro™,
DIM-Pro2™, pyridoxamine
Vitamin B12 (cobalamin)
DIM-Pro2™, Neo40®
S-Adenosyl-L-Methionine
SAMe
Vitamin C (ascorbic acid)
MinSaw™, Neo40®
Saw palmetto (Serena
Repens)
MinSaw™, Prostate-Pro2™
Vitamin E (tocopherols)
Can-C Plus™, DIM-Pro2™,
Prostate-Pro2™
Selenium
ACF228™, DIM-Pro2™,
MZS™, Prostate-Pro2™,
Selenium-Pro™,
Thym-Uvocal®
Vitamin K2
(menatretrenone)
Bone-Pro2™
Yohimbine
Vigor-Pro2™
Seligiline
Deprenyl
Zeolite
ACZ®
Silver
ACS®, Min-Mouth™
mouth rinse
Zinc
Solasodine glycosides
BEC5 Curaderm®,
Sol-Answer™
Andro-Pro™, Can-C
Plus™, Mito-Pro2™,
MZS™, Thym-Uvocal®,
Zinc-Pro™
Thiocynates
1st Line™
Thyroids
Natural brands: Armour®,
ERFA®, Nature®
Synthetic brands: Eutirox®
(T4), T3-Pro® (T3)
Supporting agents: Peptide
bioregulator (Thyreogen®)
Thyrotropin releasing
hormone
TRH
Tribulus terrestris
Andro-Pro™
TRX
Hair-Pro™
Turmeric
Curcumin
Ubiquinone, ubiquinol
CoQ10
56
AGINGMATTERS
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
TESTIMONIALS
TESTIMONIALS
DR. AUBREY DE GREY
“IAS has shown great vision and leadership, as an organisation focused mainly on the
provision of contemporary medical interventions against aging, and in also supporting
the SENS Foundation’s efforts to hasten the development of much more powerful
future interventions.”
GARRY GORDON MD,DO,MD(H)
“I am a 77 year old Physician who has practiced medicine for nearly half a century. My
antiaging research has permitted me to overcome serious health problems. Everyone can
do this, but it requires specialized knowledge and the highest quality products. IAS is a vital
link in my antiaging program because they continually provide both accurate information
AND the high quality products we all require, if we are to achieve our maximum intended
useful lifespan.
JONATHAN WRIGHT M.D.
“Every adult has the right to take care of his or her own personal health as he or she
chooses. In the 20th and 21st centuries, this universal human right has been nearly
obliterated by an ocean of nanny-state regulation and deliberate suppression of
information by bureaucracies, with hidden and not-so-hidden agendas. International
Antiaging Systems is a beacon of useful health care information and a literal island of
freedom of health care product choice in our otherwise un-free health care world.”
NICHOLAS PERRICONE M.D.
“IAS is an outstanding resource for the finest, most up-to-date news and information on
healthy aging. They also offer products of the highest integrity and efficacy. In fact, IAS is
the world’s greatest source (often the only source) for the most cutting edge and advanced
nutrients to ensure optimum healthspan and maximum life span.”
THIERRY HERTOGHE M.D.
“IAS has a history of making throughout the world crucial, but difficultly accessible
medications available to patients. IAS is one of the pioneering societies in antiaging
medicine that has helped this new medical specialty move forward."
AGINGMATTERS
57
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WEBSITES
www.antiaging-systems.com
www.antiaging-nutrition.com
www.antiaging-nootropics.com
www.antiaging-peptides.com
www.antiaging-hormones.com
www.japanias.com
www.iasjp.com
(all of our products in one place; English language)
(our nutritional products; English language)
(our smart drugs and nutrients; English language)
(our peptide bioregulators; English language)
(our hormones; English language)
(our nutritional products; Japanese language)
(our medicines and hormones; Japanese language)
EMAIL
[email protected]
[email protected]
(English language)
(Japanese language)
PHONE
USA:
Japan:
UK:
ROW:
1-866-800-4677 (orders only) 1-415-992-5563 (enquiries)
050-553-29606
0208-123-2106
+44-208-123-2106
MAIL
Unfortunately personal checks and money orders cannot be accepted at this time.
Please contact our customer service team if you need any assistance in placing your order.
note: Our customer care team is available from 9am till 6pm GMT Monday-Friday. Outside of these times your call will be
handled by our out-of-hours answering service or go to voicemail.
58
AGINGMATTERS
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
$39.99
$44.99
MinMaxPRO™
60ml liquid spray or dropper application.
Maximum strength Minoxidil, plus IGF-1, bFGF and caffeine
growth factors, plus the DHT blocker azelaic acid.
Onlne voucher code:
MINMAX-5-OFF-0117
Restrictions may apply, please see IAS terms and conditions for full details. Offer valid until 1st June 2017
All side effects and contraindications are available on the IAS website.
MARCH 2017 PRICELIST
60
AGINGMATTERS
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
MARCH 2017 PRICELIST *
Please contact us for further details.
ITEM
HORMONES
Esnatri™ (estrogens)
T3-Pro™ (T3 thyroid)
MEDICINES
Acarbose (Glucobay®)
MetPro™ (metformin)
NUTRITION
ACF228®
AminoPro™ (aminoguanidine)
Can-C™ eye-drops
Stem Cell Worx®
PEPTIDES
PEPTIDE BIOREGULATORS
SMART DRUGS
CENTROPRO™ (CENTROPHENOXINE)
Idebenone (IdebPro™)
PIRAPRO™ (PIRACETAM)
DETAILS
OFFER
50ml 100mg cream
50x 20mcg tablets
Buy 3 and save $5.00 on each pack
Buy 3 and save $5.00 on each pack
30x 100mg chewables
100x 500mg tablets
10x 100mg tablets
Buy 3 and save $5.00 on each pack
Buy 3 and save $5.00 on each pack
Buy 3 and save $5.00 on each pack
90 capsules
90x 75mg tablets
2x 5ml vials
3.5oz. liquid spray
Buy 3 and save $5.00 on each pack
Buy 3 and save $5.00 on each pack
Buy 3 and save 10% or buy 6 and save 20%
Buy 3 and save $10.00 on each pack
20x capsules
Buy 3 and save $9.99 on each pack
60x 250mg capsules
60x 30mg capsules
100x 800mg tablets
Buy 3 and save $5.00 on each pack
Buy 3 and save $5.00 on each pack
Buy 3 and save $5.00 on each pack
BOOKS
AUTHOR
PAGES
GREAT TEETH FOR LIFE
PRICE
Dr Brian Halvorsen
169 pages
$17.49
NATURAL MEDICATION FOR SKIN CANCER
Dr Bill Cham
82 pages
$19.99
PASSION, SEX, LONGEVITY & OXYTOCIN
Dr. Thierry Hertoghe
159 pages
$39.99
THE PHYSICIAN’S HORMONE HANDBOOK (VERSION 2)
Dr. Thierry Hertoghe
833 pages
$349.99
THE PICTURE ATLAS OF ENDOCRINOLOGY
Dr. Thierry Hertoghe
327 pages
$299.99
DIAGNOSTICS
FOODSAFE® NEW
CONTAINS
RETAIL
PRICE
$160
$149.99
Blood spot food allergy test-kit for 95 foods
$250
$239.99
NEO40®
25 Nitric Oxide Saliva Test Strips
$30
$24.99
VIELIGHT®
Vielight 633 intranasal LED
$295
$274.99
HORMONES
CONTAINS
RETAIL
PRICE
OTHER INFO
ALDOSTERONE
ALDO-PRO™
15x 125 mcg capsules
$90
$79.99
ALDO-SPRAY™ NEW
5ml 10mg ear spray
$140
$59.99
2.5ml nasal spray
$30
$24.99
DHEA-25-PRO™ NEW
60 x 25mg capsules
$20
$17.49
DHEA 7-KETO NEW
60x 100mg capsules
$40
$34.99
$45
$39.99
$60
$49.99
DESMOPRESSIN
MINURIN®
DHEA
ESNATRI™ (BIOIDENTICAL TRIPLE ESTROGENS)
ESNATRI™
50ml 100mg (90-7-3%) jar cream
HCG (HUMAN CHORIONIC GONADOTROPIN)
HCG-PRO™
250IU/5ml nasal spray
AGINGMATTERS
61
MARCH 2017 PRICELIST *
HORMONES
CONTAINS
OTHER INFO
RETAIL
PRICE
100 x 5mg capsules
$20
$17.49
MZS™ (*UK C AN O RD ER V IA
WW W.ME LATONINZ NSE. COM)
60x 3mg tablets
$25
$22.49
MELA-MAX™
60x 10mg capsules
$25
$21.49
2 oz. 90mg liquid
$20
$17.49
5ml 500IU nasal spray
$60
$49.99
100x 5IU lozenges
$50
$42.49
HYDROCORTISONE
HYDROCORT-PRO™
MELATONIN
MELA-PRO™
NEW
NEW
MSH (MELANOCYTE STIMULATING HORMONE)
MSH2-PRO™
OXYTOCIN
OXY-LOZENGE™
NEW
OXY-PRO™
5ml 500IU nasal spray
$45
$39.99
OXY-SUB20™
30x 20IU sublingual trouches
$80
$69.99
50x 100mg capsules
$25
$19.99
50ml 2.5G cream
$35
$29.99
90x 200mg capsules
$110
$99.99
100x 30mg tablets
$60
$59.99
PREGNENOLONE
PREG-PRO™
PROGESTERONE (BIOIDENTICAL 5%)
PROGEST-PRO™
THYMUS
THYM-UVOCAL®
THYROIDS (NATURAL)
ERFA®
ERFA®
100x 60mg tablets
$80
$79.99
ERFA®
100x 125mg tablets
$130
$129.99
NATURE®
100x 15mg tablets
$50
$39.99
NATURE®
100x 32.5mg tablets
$60
$49.99
NATURE®
100x 65mg tablets
$70
$59.99
NATURE®
100x 97.5mg tablets
$80
$69.99
NATURE®
100x 130mg tablets
$90
$79.99
T3 (T3-PRO™)
50x 20mcg tablets
$35
$29.99
T4 (EUTIROX®)
50x 150mcg tablets
$25
$19.99
20x 5mg sublingual tablets
$220
$199.99
VASO-PRO™
5ml 500IU nasal spray
$60
$49.99
MEDICINES
CONTAINS
THYROIDS (SYNTHETIC)
TRH (THYROTROPIN RELEASING HORMONE)
ABARIS™
VASOPRESSIN
OTHER INFO
RETAIL
PRICE
30 x 100mg chewable tablets
$25
$19.99
28x 1mg tablets
$70
$59.99
30x 2.5mg tablets
$25
$19.99
8x 0.5mg tablets
$50
$39.99
ACARBOSE
GLUCOBAY®
ANASTROZOLE
ARIMIDEX®
BROMOCRIPTINE
PARLODEL®
CABERGOLINE
DOSTINEX®
62
AGINGMATTERS
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
MARCH 2017 PRICELIST *
MEDICINES
CONTAINS
OTHER INFO
RETAIL
PRICE
CIPROFLOXACIN
CIPRO®
14x 500mg tablets
$25
$19.99
14x 100mg tablets
$20
$14.99
30x 0.5mg capsules
$50
$39.99
28x 5mg tablets
$30
$24.99
DOXYCYCLINE
MONODOKS®
DUTASTERIDE
AVODART®
FINASTERIDE
PROSCAR®
METFORMIN
GLUCOPHAGE®
MET-PRO™
NEW
NEW
100x 850mg tablets
$30
$24.99
100x 500mg tablets
$25
$19.99
30x 4.5mg capsules
$55
$44.99
30x 1mg capsules
$90
$79.99
60x 4mg tablets
$50
$39.99
10x 50mg tablets
$25
$19.99
10x 100mg scored tablets
$25
$19.99
60x 12.5mg tablets
$60
$49.99
16x 250mg tablets
$20
$14.99
28x 25mg tablets
$150
$134.99
14x 37.5mg capsules
$20
$14.99
NALTREXONE (LDN)
NAL-PRO™
RASAGILINE
AZILECT®
REBOXETINE (DAVEDAX®)
EDRONAX®
ROXITHROMYCINE
RULID®
SILDENAFIL (GENERIC VIAGRA®)
SILDENAFIL-PRO™
NEW
STABLON® (TIANEPTINE)
STABLON® (TIANEPTINE)
TETRACYCLINE
TETRA®
VALDOXAN® (AGLOMELATINE)
VALDOXAN® (AGLOMELATINE)
VENLAFAXINE
EFEXOR®
NEW
NUTRITION
CONTAINS
OTHER INFO
RETAIL
PRICE
OSCN kit
$90
$79.99
90x 100mg capsules
$25
$21.49
ACF228®
50x capsules
$60
$49.99
INHALER (BREATHE-EASY™)
1 complete kit
$150
$134.99
90x 75mg tablets
$20
$17.49
60x capsules
$45
$39.99
1ST LINE™
1ST LINE™
5HTP (5-HYDROXY-TRYPTOPHAN)
5HTP-PRO2™
ACF228®
AMINOGUANIDINE
AMINO-PRO™
ANDRO-PRO2™
ANDRO-PRO2™
NEW
AGINGMATTERS
63
MARCH 2017 PRICELIST *
NUTRITION
CONTAINS
OTHER INFO
RETAIL
PRICE
BETA-GLUCANS
BG-CREAM™
NEW
50ml tube cream
$45
$39.99
60x 400mg capsules
$35
$29.99
120x 180mg capsules
$25
$21.49
60 capsules
$110
$94.99
60 capsules
$35
$29.99
90 capsules
$40
$34.99
30x 100mg capsules
$20
$17.49
30x 125mg capsules
$15
$12.49
100x capsules
$50
$42.49
60x 100mg capsules
$45
$39.99
120x 10mg capsules
$30
$24.99
60x 250mg tablets
$20
$17.49
GEROVITAL-H3®
5x 5ml ampoules
$60
$49.99
GEROVITAL-H3® ORIGINAL
24x 100mg tablets
$35
$29.99
GH3-PRO™
60x 100mg tablets
$20
$14.99
30 x 500mg Capsules
$30
$24.99
50x 250mg capsules
$25
$21.49
100x 5mg capsules
$20
$17.49
50x 500mg capsules
$20
$17.49
BG-CAPS™
NEW
BHT (BUTYLHYDROXYTOLUENE)
BHT-PRO™
BOLUOKE® (LUMBROKINASE)
BOLUOKE® (LUMBROKINASE)
BONE-PRO2™
BONE-PRO2™
CAN-C™ PLUS
CAN-C™ PLUS
COQ10 (COENZYME Q10)
COQ10-SR™
CURCUMIN
CURCUMIN-SR™
DI-INDOLYMETHANE
DIM-PRO2™
DMSA
DMSA-PRO™
NEW
EDTA
EDTA-PRO™
NEW
GABA/GABOB
RELAX-PRO™
NEW
GEROVITAL-H3®
GREEN COFFEE BEAN EXTRACT
GCB70-PRO™
L-CARNOSINE
CARNO-PRO™
LITHIUM OROTATE
LITH-PRO™
L-TRYPTOPHAN
L-TRYP-PRO™
64
AGINGMATTERS
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
MARCH 2017 PRICELIST *
NUTRITION
CONTAINS
OTHER INFO
RETAIL
PRICE
MINERAL MOUTHWASH
MIN-MOUTH™
NE W
16 oz. liquid bottle
$20
$17.49
75G powder
$55
$49.99
60x 5mg capsules
$70
$69.99
15x 5mg capsules
$24
$20.99
30x lozenges
$60
$59.99
30x 260mg capsules
$55
$49.99
30x 5ml liquid sachets
$30
$29.99
30 x 100mg capsules
$60
$54.99
120x 725mg capsules
$40
$34.99
236ml bottle liquid
$45
$39.99
30x 20mg capsules
$35
$29.99
30x 150mg capsules
$20
$14.99
20x 400mg enteric coated tablets
$35
$29.99
15ml 15ppm spray bottle
$15
$14.99
3.5oz mouth spray
$65
$64.99
4x 500ml liquid bottles
$95
$94.99
TA65®
90x capsules (250 dose)
$600
$599.99
TA65®
30ml bottle cream
$500
$499.99
30 x 500mg Capsules
$30
$24.99
MITO-PRO2™
MITO-PRO2 ™
MITOQ®
MITOQ®
NE W
NADH
RECONNECT®
NE W
NEO40®
NEO40®
NICOTINAMIDE RIBOSID
NAD+PRO™
E
NE W
NOVISYN® (HYALURONIC ACID)
NOVISYN® (HYALURONIC ACID)
OXALOACETATE
OXALO-PRO™
NE W
PEO (PARENT ESSENTIAL OILS)
PEO-PRO™
PEO-LIQUID™
NE W
PQQ (PYROLOQUINOLINE QUINONE
)
PQQ-PRO™
RESVERATRO L
RESVERATROL-SR™
SAME (S-ADENOSYL-L-METHIONE
)
SAME-PRO™
SILVER
SILVER NANO - SPRAY
STEM CELL WORX®
STEM CELL WORX®
SYMPROVE®
SYMPROVE ®
TA65®
TRIGONELLA FOENUM-GRAECUM SEED
FENFURO-PRO™
PEPTIDES
CONTAINS
OTHER INFO
RETAIL
PRICE
$175
$159.99
GHRP- 2
GHRP2-PRO ™
120ml 120mg bottle liquid
AGINGMATTERS
65
MARCH 2017 PRICELIST *
GHRP-6
RELEASE-PRO™
5ml 500 IU nasal spray
$70
$59.99
20x capsules
$70
$59.99
20x capsules
$70
$59.99
20x capsules
$70
$59.99
20x capsules
$70
$59.99
BRAIN/ CNS (CERLUTEN®)
20x capsules
$70
$59.99
CARTILAGE (SIGUMIR®)
20x capsules
$70
$59.99
HEART (CHELOHART®)
20x capsules
$70
$59.99
KIDNEYS (PIELOTAX®)
20x capsules
$70
$59.99
LIVER (SVETINORM®)
20x capsules
$70
$59.99
20x capsules
$70
$59.99
MUSCLE (GOTRATIX®)
20x capsules
$70
$59.99
OVARIES (ZHENOLUTEN®)
20x capsules
$70
$59.99
PANCREAS (SUPREFORT®)
20x capsules
$70
$59.99
PEPTIDE BIOREGULATORS
ADRENALS (GLANDOKORT®)
BLADDER (CHITOMUR®)
NEW
BLOOD VESSELS (VENTFORT®)
BONE MARROW (BONOMARLOT®)
LUNGS (TAXOREST®)
NEW
NEW
PARATHYROID (BONOTHYRK®)
NEW
20x capsules
$70
$59.99
PINEAL (ENDOLUTEN®)
20x capsules
$90
$79.99
PROSTATE (LIBIDON®)
20x capsules
$70
$59.99
RETINA (VISOLUTEN®)
20x capsules
$70
$59.99
STOMACH MUCUS (STAMAKORT®)
20x capsules
$70
$59.99
TESTES (TESTOLUTEN®)
20x capsules
$70
$59.99
THYMUS (VLADONIX®)
20x capsules
$70
$59.99
THYROID (THYREOGEN®)
20x capsules
$70
$59.99
30ml/ 30mg liquid
$195
$179.99
5ml 500IU nasal spray
$55
$44.99
SERMORELIN
SERM-PRO™
SERM-SPRAY™
NEW
SMART DRUGS
CONTAINS
OTHER INFO
RETAIL
PRICE
40x 300mg capsules
$50
$39.99
20x 750mg capsules
$25
$21.49
60x 250mg capsules
$25
$22.49
DEP-PRO™
20ml 300mg bottle liquid
$90
$84.99
DEP-TABS™ NEW
50x 5mg tablets
$40
$34.99
60x 2.25mg capsules
$45
$39.99
ADRAFINIL
ADRA-PRO™
ANIRACETAM
ANI-PRO™
CENTROPHENOXINE
CENTRO-PRO™
DEPRENYL (SELIGILINE)
HYDERGINE® (ERGOLOID MESYLATE)
HY-PRO2™
66
NEW
AGINGMATTERS
www.antiaging-systems.com | Order Hotline: 1-866-800-4677 | Email: [email protected]
MARCH 2017 PRICELIST *
SMART DRUGS
CONTAINS
OTHER INFO
RETAIL
PRICE
IDEBENONE
IDEB-PRO™
60x 30mg tablets
$30
$24.99
60x 50mg tablets
$20
$17.49
NOOTROPIL®
30x 800mg tablets
$15
$12.49
NOOTROPIL®
20G 200ml bottle liquid
$20
$17.49
100x 800mg tablets
$25
$19.99
40x 300mg tablets
$50
$44.99
VIN-PRO™
120x 10mg capsules
$30
$24.99
TOPICALS
CONTAINS
PICAMILONE
PICAMILON-PRO™
PIRACETAM
PIRA-PRO™
PRAMIRACETAM
PRAM-PRO™
VINPOCETINE
OTHER INFO
RETAIL
PRICE
20ml tube cream
$150
$144.99
2x 5ml vials
$45
$39.99
200ml bottle shampoo
$20
$17.49
60ml spray bottle
$50
$44.99
50ml tube RNA toothpaste
$10
$9.99
30ml 0.050% cream
$45
$39.99
BODY MILK
200ml bottle
$50
$44.99
DAY CREAM
50ml pump
$70
$64.99
BEC5 CURADERM®
BEC5 CURADERM®
CAN-C™ EYE-DROPS
CAN-C™ EYE-DROPS
DERCOS® (AMINEXIL)
DERCOS® (AMINEXIL)
MINMAX-PRO™ (HAIR LOSS LOTION)
MINMAX-PRO™
NEW
NEYDENT®
NEYDENT®
RETIN-A® (TRETINOIN/ RETINOLIC ACID)
RETIN-PRO™
YOUTH GEMS®
FACE PACK NEW
NIGHT CREAM
NEW
100ml bottle
$55
$49.99
$64.99
50ml pump
$70
SERUM
30ml dropper bottle
$90
$79.99
TONIC
200ml liquid bottle
$45
$39.99
RETAIL
PRICE
OTHERS
CONTAINS
OTHER INFO
INJECTION PACKS
INTRAMUSCULAR
30x syringes, wipes and sharps
$30
$24.99
SUBCUTANEOUS
30x syringes, wipes and sharps
$30
$24.99
AGINGMATTERS
67
Turn back
the clock
with this potent
AGE* inhibitor
(AGE = advanced glycated
end-products)
Aminoguanidine AminoPro
TM
Offer Price: $14.49 (Usual Price: $17.49)
ONLINE CODE: AMINOPRO-3-OFF-0117
Restrictions may apply please see IAS terms and conditions for full details. Offer valid until 1st June 2017.
68
AGINGMATTERS
All side effects and contraindications are available on the IAS website.