Blood Transfusion in Animals By Dr Florence Chan There are many situations where animals require urgent blood transfusion. Road accident causing external and internal bleeding, high-rise syndrome in cats (ie falling from high-rise apartment windows), rat-bait poisoning, profound anaemia caused by tick fever or autoimmune disease, tumour in the spleen and/or liver or stomach ulcers causing massive internal bleeding etc. It might surprise a few people that our dogs and cats can receive blood transfusion, and that often saves lives. Dogs and cats, just like human, have different blood types. Dogs have many different blood types (more than 10), making it difficult to categorize individual dog’s blood group with commercial test kits. The good news is, however, dogs do not have natural antibodies against other blood types, meaning that we don’t have to match the blood type between donor dog and recipient dog in the first blood transfusion. However subsequent transfusions might invoke serious reactions and so it is recommended to perform a crossmatch between donor and recipient before any subsequent blood transfusion. The situation in cats is a little bit similar to human. Cats have the following blood type: A, B and AB. Majority of cats have type A blood, while certain pedigrees e.g. British Shorthaired and Exotics, appear to have a higher prevalence of type B cats. Cats have natural-occurring antibodies against other blood groups and can develop potentially severe allergic reactions when the wrong blood type is being transfused. The situation is the worst and can be fatal when a type B cat is given type A blood. As a result, it is always recommended to identify the blood type of both the donor cats, and the recipient cats and to always perform a cross-match before any blood transfusion to be certain of their compatibility. There is currently no commercial blood bank for our dogs and cats in Hong Kong, so where do we find blood when we need it? Some clinics purchase blood products from overseas canine commercial blood banks. Both packed red blood cells and fresh frozen plasma are available commercially, being collected from universal donors and then processed to the desired products. The advantages of such products are immediate availability (when in stock) and quality assurance (standardized donor – disease-free). The disadvantages of these are the high cost, limited shelf-life, shipment from overseas not always available, and the lack of platelets and other blood proteins that would be beneficial in some coagulopathies. Also, currently there is no feline blood product available for purchase. Another option is to find donor animals to come in for blood donation, then immediately transfuse the donated blood to our patients. Most clinics rely on their staff’s pets, or goodhearted clients to bring their animals in for donation when blood is needed for another patient. Most owners are actually quite happy for their pets to “fulfill their duties towards their own kind” and be a hero when approached! What makes the perfect donor animal? Young, healthy and friendly > 25kgs (dogs) and > 4kgs (cats) Up to date with vaccination, heartworm prevention and deworming Never received a blood transfusion before Never been pregnant (females only) Free of any blood-borne disease (e.g. tick fever) During the blood collection process sedation is sometimes required. The process usually doesn’t take more than 1/2 hour and we usually allow the donor animal to rest for a while before sending them home. There should not be any detrimental effect to our donors after the donation. 2
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