Metabolism & Communication Study Guide Things you need to know/ be able to answer: CELL COMMUNICATION (CH11) 1. Quorum sensing 2. Types of signaling a. Cell-to-cell contact b. Local c. Long-distance 3. What is a signal transduction pathway? 4. 3 stages of signal transduction pathway a. Reception 3 types of membrane receptors b. Transduction c. Response 5. How a signaling pathway can amplify a signal 6. Apoptosis & what failure of it can lead to ENZYMES (CH8) 7. Metabolic pathways & two types 8. Laws of Thermodynamics & how life is able to adhere to the laws 9. Entropy 10. Endergonic vs. exergonic reactions (relate to catabolic and anabolic reactions) 11. Structure and use of ATP & ADP (hydrolysis) 12. Enzyme = catalyst/ know it’s function & how it does its job 13. Induced fit 14. Effects of local conditions on enzyme activity 15. Allosteric regulation of enzymes 16. Feedback inhibition CELL RESPIRATION (CH9) 17. Formula for cellular respiration 18. Is Respiration catabolic or anabolic? 19. Two “types” of cellular respiration 20. The three phases of aerobic cellular respiration a. Where each occurs in a cell (eu and pro)/ mitochondria b. What are the reactants (input) c. What are the products (output) d. How much ATP is made e. Basic explanation of the phase 21. Types of fermentation & their products 22. Evolutionary significance of glycolysis PHOTOSYNTHESIS (CH10) 23. Formula for photosynthesis 24. It is catabolic or anabolic? 25. Pigment used by chloroplasts? Which colors does it use & why? 26. Where it happens in a cell (pro & eu) 27. Two phases of photosynthesis a. Where each occurs in the chloroplast b. What goes in? What comes out? c. Why does it occur? d. Basic explanation of the phases 28. Difference between C3, C4 and CAM plants 29. What is photorespiration? FRQ Topic Possibilities: Cell Communication (stages of signal transduction pathways) Photosynthesis o process o designing a lab o removing a reactant Respiration o process o designing a lab o removing a reactant Example Questions: Describe the similarities and differences between the biochemical pathways of aerobic respiration and photosynthesis in eukaryotic cells. Include in your discussion the major reactions, the end products, and energy transfers. Aerobic respiration Type of reaction Catabolic / exergonic Cell organelle Mitochondria Steps & Location 1. Glycolysis – cytosol 2. Krebs/ Citric Acid Cycle – mito matrix Both Anabolic/endergonic -----------------ETC & Chemiosmosis Inner mitochondrial memrbane Reactants Products chloroplast 2. Calvin Cycle - stroma Thylakoid membrane O2, C6H12O6 H2O, ATP, CO2 Photosynthesis H2O, light, CO2 ------------------- O2, C6H12O6 The overall equation for aerobic respiration is usually written as the reverse of the overall equation for photosynthesis. What features of the biochemical pathways involved in the processes are the reverse of one another and what features are not? Two flasks with identical medium containing nutrients and glucose are inoculated with yeast cells that are capable of both anaerobic and aerobic respiration. Culture 1 is then sealed to prevent fresh air from reaching the culture; Culture 2 is loosely capped to permit air to reach the culture. Both flasks are periodically shaken. Which of the following best predicts which culture will contain more yeasts cells after one week, and most accurately justifies that prediction? A. Culture 1, because fresh air is toxic to yeast cells and will inhibit their growth. B. Culture 1, because fermentation is a more efficient metabolic process than cellular respiration. C. Culture 2, because fresh air provides essential nitrogen nutrients to the culture. D. Culture 2, because oxidative cellular respiration is a more efficient metabolic process than fermentation. The figure above represents a generalized hormone-signaling pathway. Briefly explain the role of each numbered step in regulating target gene expression. 1. Reception -Hormone/ligand binding to receptor to initiate/trigger/induce/start signaling or signal reception 2. Transduction- An intracellular cascade that transduces/amplifies/transfers the signal from plasma membrane to its designated location 3. Response - the transduced signal (say kind of various kinases) triggers a specific cellular activity
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