S EDPEC IT IA IO L N ISSUE NO. 1 // JAN 2017 MS ACPN Multiple Sclerosis Unit The American Centre for Psychiatry and Neurology is pleased to announce the launch of the Multiple Sclerosis Unit! After a lot of hard work from all the staff at the American Center for Psychiatry and Neurology, we are very pleased to have officially begun the Multiple Sclerosis Program. The literature suggest that people with Multiple Sclerosis ( MS) make greater improvements while under the care of experienced clinicians within a specialized Multiple Sclerosis service. The American Center for Psychiatry and Neurology is the first of its kind in the UAE to offer a specialized, coordinated multidisciplinary management of MS, with patients able to access a range of services and treatments tailored specifically to their individual needs. This includes Specialist Neurologists, Physiotherapists, Occupational Therapists, Speech and Language Therapists, Psychiatrists, Psychologists, Nurses and Pharmacists - all with experience in the management of Multiple Sclerosis. It is an exciting time at the American Center and we look forward to welcoming more patients to our unit. Multiple Sclerosis Unit Launch The launch of the Multiple Sclerosis Unit went off with a bang at the Beach Rotana in Abu Dhabi! ACPN kicked off the launch of the MS Unit with an educational symposium on the 28th October 2016, held at Beach Rotana - Abu Dhabi. The seminar was attended by over 160 high profile doctors and medical experts. The half day symposium consisted of numerous presentations from leading clinicians including our very own Consultant Neurologist, Dr Taoufik Al Saadi, and Professor Peter Rieckmann – Research Chair of the Canadian Multiple Sclerosis Society, who flew in especially for the event. The symposium was a great success and well received by all attendees. We thoroughly enjoyed meeting colleagues from other healthcare centers in the Emirate and answering their questions about the management of Multiple Sclerosis. ASK THE EXPERT Each month, we put your questions to one of ACPN’s resident Multiple Sclerosis Experts Dr Taoufik Al Saadi is a Consultant Neurologist and Chief Medical Officer at the American Center for Psychiatry and Neurology. He is American board certified and has extensive experience in both the USA and the UAE, previously working as the Head of Neurology at Sheikh Khalifa Medical City. As well as being honored with many prestigious awards in the field of Neurology, he has also co-authored numerous articles and book chapters to advance research and knowledge in Multiple Sclerosis. This month, we asked Dr Taoufik to answer your questions on what Multiple Sclerosis is and what causes it… IN THE NEWS approximately 15 percent. This has led to general recognition of optic neuritis as an early sign of MS. Most MS patients experience muscle weakness in their extremities and difficulty with coordination and balance at some time during the course of the disease. These symptoms may be severe enough to impair walking or even standing. In the worst cases, MS can produce partial or complete paralysis. Most people with MS also exhibit paresthesias, transitory abnormal sensory feelings such as, numbness, prickling, or "pins and needles" sensations; uncommonly, some may also experience pain. Loss of sensation sometimes occurs. Speech impediments, tremors, and dizziness are other frequent complaints. My mom has Multiple Sclerosis, does this mean I will get it too? Family history of MS is one of the strongest overall risk factors for the disease. Siblings have a 30- to 50-fold increase in risk and first-degree relatives have a 7-fold increase in risk compared with the general population. This strongly suggests that genetics, at least in part, contributes to MS causality Briefly, what is Multiple Sclerosis and what are the main symptoms? MS is a chronic progressive and inflammatory neurodegenerative disease that affects the central nervous system. There are 3 pathological components associated with this disease including inflammation, demyelination, and axonal loss. During an MS attack, inflammation occurs in areas of the white matter of the central nervous system in random patches called plaques. This process is followed by destruction of myelin, the fatty covering that insulates nerve cell fibers in the brain and spinal cord. Myelin facilitates the smooth, high-speed transmission of electrochemical messages between the brain, the spinal cord, and the rest of the body; when it is damaged, neurological transmission of messages may be slowed or blocked completely, leading to diminished or lost function. It is worth mentioning here that recent data suggest that axonal loss occurs very early in the course of the disease. Symptoms of MS may be mild or severe, of long duration or short, and may appear in various combinations, depending on the area of the nervous system affected. Complete or partial remission of symptoms, especially in the early stages of the disease, occurs in approximately 70 percent of MS patients. The initial symptom of MS is often blurred or double vision, red-green color distortion, or even blindness in one eye. . Fifty-five percent of MS patients will have an attack of optic neuritis at some time or other and it will be the first symptom of MS in I had some numbness in my fingers a few weeks ago and I have been told I might have Multiple Sclerosis. How can I know for certain? Patients may have numbness in the fingers due to variety of neurological as well as others systemic disorders. If the evaluation reveals an abnormality that warrants further investigations, additional testing may be required. Generally, patients with suspected diagnosis of MS will need to undergo an imaging study and, in some cases, a lumbar puncture to confirm the diagnosis What should I do if I experience some of the symptoms of Multiple Sclerosis? An experienced and a qualified neurologist is your best resource of advice on how to manage these symptoms. Often times, the neurologist may have to consult other specialists in his team to address some of your complaints such as, mood disorder, speech and language difficulties, fatigue, physical impairment, among many other symptoms. 800 ACPN (2276) [email protected] Disease Modifying Treatments (DMTs) may be able to reverse MS Symptoms for some people According to a recent study published in the Journal of Neurology, DMTs may actually be able to reverse the symptoms of MS, not just prevent its worsening. In this study, researchers measured symptoms on the Expanded Disability Status Scale (EDSS), which looks at a number of different factors, including problems with walking, thinking and swallowing. These symptoms were measured for 2 years following treatment, and compared those taking alemtuzumab (a newly FDA approved DMT) with those taking interferon beta 1a. After two years, 27% of people taking alemtuzumab had improved by at least one point on the EDSS, compared to 15% of those taking interferons. DMTs have been known to slow progression of disability and reduce relapse rates, but this is the first long term study of its kind to look specifically at improvement of symptoms. Many of these treatments are too new for us to know exactly how long the benefits will last. But the evidence so far makes us hopeful that people starting treatment early after diagnosis will dramatically change the course of their condition. To find out more about Multiple sclerosis and how to manage it, please contact 800 ACPN (2276) or speak to your Neurologist or clinical Coordinator. www.americancenteruae.com
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