Your blood count Exceptional healthcare, personally delivered Your blood count The circulation Blood moves around the body inside the blood vessels called arteries, veins and capillaries. Blood is pumped through these vessels by the heart. What is blood made of? The average adult human has about 5 litres (just under 9 pints) of blood. About 50% of the blood is made up of plasma constituting the fluid part of the blood. The cells and platelets that are present in our blood make up the other 50%. Red cells Red blood cells Red blood cells make up about 45% of the blood volume and give it colour. Neutrophil There are more than 4 million of them in every cubic millimeter of blood. A red blood cell can live for up to 120 days and new ones are constantly being made. Red blood cells carry oxygen to the tissues. When they get to an area where the oxygen is needed, they give it up and pick up carbon dioxide that they carry back to the lungs. Anaemia is a lack of red blood cells. Lymphocyte White blood cells There are several different types of white blood cells that together make up about 3% of blood. The most numerous are the neutrophils. They act in the body’s response to bacterial infection, can be made very quickly and have a short lifespan. 2 Your blood count Eosinophil The next most numerous are lymphocytes, part of the immune system and involved in making antibodies. Monocytes, eosinophils and basophils are other white cells that are present in smaller numbers. Platelets Platelets make up about 2% of the blood. They are small bits of much bigger cells (megakaryocytes, found in the bone marrow). When blood clots they clump together to form a plug and then secrete factors that help make the clot and start repair of the damaged blood vessel. Monocyte Where are blood cells made? All blood cells develop from a ‘blood stem cell’ found in the bone marrow of the skull, ribs, sternum (breast bone), spine and pelvis. For this reason, a sample (biopsy) of bone marrow can be examined under the microscope and tested in other ways to help to find the cause of an abnormality in the blood count. Basophil Plasma Plasma is 92% water, 7% protein, 1% minerals, plus vitamins, sugar, and fats. It also contains clotting factors and antibodies. Plasma carries nutrition to all parts of the body and then carries away waste products for removal from the body. Platelets Your blood count 3 What is a full blood count? A blood sample is taken, usually from a vein. It is prevented from clotting by a chemical in the blood bottle so that it will remain liquid for analysis. The blood tube is put into a machine which sucks out a sample and automatically: nn Measures the haemoglobin. nn Counts the number of red cells, white cells, and platelets. nn Measures the size of the red blood cells. nn Calculates the proportion of blood made up from red blood cells (the haematocrit). These results are known as a full blood count. Full Blood Count Reference ranges: Man Woman Haemoglobin g/dl 13.0 - 17.0 11.5 - 16.0 Haematocrit 0.4 - 0.54 0.37 - 0.47 White cells x109/l 4.0 - 11.0 4.0 - 11.0 Neutrophils x109/l 2.0 - 7.5 2.0 - 7.5 Lymphocytes x109/l 1.5 - 4.0 1.5 - 4.0 Monocytes x109/l 0.2 - 0.8 0.2 - 0.8 Eosinophils x109/l 0.04 - 0.4 0.04 - 0.4 Basophils x109/l 0 - 0.1 0 - 0.1 Platelets x109/l 150 - 400 150 - 400 NHS Constitution. Information on your rights and responsibilities. Available at www.nhs.uk/aboutnhs/constitution 4 Your blood count How to contact us: See your appointment letter for the number to phone with any queries you may have www.nbt.nhs.uk If you or the individual you are caring for need support reading this leaflet please ask a member of staff for advice. © North Bristol NHS Trust. This edition published May 2014. Review due May 2016. NBT002080
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