One Stop Shop For Educators The following instructional plan is part of a GaDOE collection of Unit Frameworks, Performance Tasks, examples of Student Work, and Teacher Commentary. Many more GaDOE approved instructional plans are available by using the Search Standards feature located on GeorgiaStandards.Org. Georgia Performance Standards Framework for Biology 9-12 Unit: Equilibrium General Task Have You Eaten Yet? Overview: The overall outcome of this extension activity is to help students connect that the traits most favorable for survival are determined by environmental pressures such as parasites, disease, predator prey relationship, and other environmental pressures. Standards: SB5. Students will evaluate the role of natural selection in the development of the theory of evolution. b. Explain the history of life in terms of biodiversity, ancestry, and the rates of evolution. d. Relate natural selection to changes in organisms. SB4. Students will assess the dependence of all organisms on one another and the flow of energy and matter within their ecosystems. f. Relate animal adaptations, including behaviors, to the ability to survive stressful environmental conditions. SCSh3. Students will identify and investigate problems scientifically. a. Suggest reasonable hypotheses for identified problems. b. Develop procedures for solving scientific problems. c. Collect, organize and record appropriate data. d. Graphically compare and analyze data points and/or summary statistics. e. Develop reasonable conclusions based on data collected. f. Evaluate whether conclusions are reasonable by reviewing the process and checking against other available information. Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 1 of 15 Copyright 2007 © All Rights Reserved One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 SCSh4. Students will use tools and instruments for observing, measuring, and manipulating scientific equipment and materials. a. Develop and use systematic procedures for recording and organizing information. b. Use technology to produce tables and graphs. SCSh6. Students will communicate scientific investigations and information clearly. a. Write clear, coherent laboratory reports related to scientific investigations. c. Use data as evidence to support scientific arguments and claims in written or oral presentations. SCSh8. Students will understand important features of the process of scientific inquiry. e. The ultimate goal of science is to develop an understanding of the natural universe which is free of biases. Enduring Understandings: • • • • Natural selection is a primary factor in evolutionary change. Favorable variations among individuals that increase the chance of survival tend to be passed onto successive generations. Diversity among organisms is due to adaptations to changing environmental conditions. Evolution is a consequence of the interactions of o a finite supply of resources required for life o the selection by the environment of those offspring better able to survive and leave offspring. Essential Questions: 1. How is natural selection essential to evolution? 2. How does natural selection drive the adaptations that increase the fitness of an organism for its environment? 3. How do interrelationships and interdependencies of organisms generate survivable adaptations? Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 2 of 15 Copyright 2007 © All Rights Reserved One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 Outcome / Performance Expectations: General Teacher Instructions: Materials Needed: Safety Precautions: Task with Student Directions: • Explain the adaptations of the organism that enable the organism to be successful within the ecosystem. • Identify the effects of biodiversity, mutations, natural selection have on the survival rate of the species based on “fitness”. • Explain how favorable variations among individuals that increase the chance of survival by passing on those traits into the next generation. • Explain how the relationship of predator and prey adaptations leads to the overall survival for each organism. Teacher Notes: Background information can be presented with pictured or a video to describe the predator prey relationships. Background_info ( click background info- can be printed and laminated for student use) Extension Activity Sickle_cell: (click to view) Teacher can use the “Cat Drop” performance task as a follow-up activity to make the activity more effective when teaching the equilibrium framework. 3 different kinds of dry beans: kidney, split peas, chickpeas, pinto beans, black eyed peas, etc… (Must be three different colors and sizes.) One bucket or tray to mix beans. One paper cup for each student for hunting and gathering. Hunting Utensils for a group of four: plastic spoon, fork, forceps, 2 chopsticks (substitutions for utensils could be to have student hunt beans using thumb and pinky fingers in a pinching motion.) 3 Hunting Areas: 1m squared plot of a grassy area, concrete/pavement, color paper or gift-wrapping of a bright color. Tape, chalk or string. Data table for each student and stopwatch for timing. Be careful with use of utensils in lab investigation. Procedures for: Have you eaten yet? Lab 1. Create 3- 1m2 areas which will be the hunting areas. Tape (string) or chalk-off an area on a concrete walkway or pavement and an area in the grass. The third area can be a piece of bulletin board paper of any color except white or green. A colorful piece of gift wrapping paper would do nicely. Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 3 of 15 Copyright 2007 © All Rights Reserved One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 2. Supply enough beans (about 50) for data collection for 30 second hunting time. 3. Spread a population of beans on the areas. A mixture of at least 3 different kinds of beans (kidney beans, lentils or split peas, blackeyed peas) will be the prey population. 4. Give each group of 4 students 4 utensils with which they will hunt the prey (a plastic spoon, a plastic fork, forceps, and chop sticks). 5. Station each group around a hunting area and assign them a hunting utensil. Allow the students 30 seconds to capture as many of the beans as possible with the utensil they were given. NOTE: The students can only use the hunting utensil they were given. “Caught” prey can be collected in a paper cup. 6. Count the caught beans that are left and record in CAUGHTBEANS table.. 7. The students should count the remaining beans and record in the BEANS_THAT_SURVIVED table. 8. The groups should then rotate to the next hunting area until every group has hunted in each area. 9. The “caught” prey can be dumped into a large bucket where they can be mixed and stored until the next class. Analysis & Conclusion Questions: 1. Which of the beans is least adapted to the environment in which it was hunted? What data supports your answer? 2. Which beans seem to best adapted to the environment in which it was hunted? What data supports your answer? 3. How did the hunting event affect the genetic variation of the bean population? 4. Does natural selection act on the genotype or phenotype of the individual beans? 5. How do natural selection and predation affect the gene pool of the bean population? 6. What did the experiment show about how prey is selected by predators? 7. How does this simulation model natural selection? 8. Count all the beans that appear to be flawed or damaged. Compare that count to the total count for each bean its kind. What is the total for flawed beans? 9. Consider the flaws in the beans as phenotypes which result from genetic mutations. Give reasons for why the flawed phenotype was preserved by natural selection? Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 4 of 15 Copyright 2007 © All Rights Reserved One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 Resources: http://nces.ed.gov/nceskids/createagraph/default.aspx Teacher Resources: Adapted from Genetics Education Partnership. A simulation lab could be used from this source to teach how natural selection shapes allelic frequency. http://genetics-education-partnership.mbt.washington.edu/class/activities/HS/sickle-bean.htm July 2007 article on Malaria Malaria: Stopping a Global Killer. http://www7.nationalgeographic.com/ngm/0707/feature1/index.html Homework / Extension: Research one predator-prey relationship and describe in a paragraph how coevolution has occurred to maintain the relationship. You may also bring in a creative drawing or a story that addresses the adaptations for survival in your chosen relationship. Instructional Task Accommodations for ELL Students: • • • • • Instructional Task Accommodations for Students with Specific Disabilities: Create a word wall for vocabulary possibly with pictures; a word wall can be an interactive whereby students use string to make connections with key vocabulary Modify language requirements for written work/ lab report Pair with more advanced native language speaking partner ( allow for translation in native language for comprehension) as needed For lab report / written work provide paragraph summary template ( fill in the blank format) Provide native language text books and support material whenever possible • Review and Implement IEP accommodations for specific student needs Other accommodations that may be implemented • Word bank of key vocabulary for written work/ lab report • Create a word wall for vocabulary; word wall can be an interactive whereby students use string to make connections with key vocabulary • Include illustrations with the word wall ( visual learner) • Use KIM vocabulary strategy ( Key word, Illustration, and Meaning student in students own words • Provide a check-list for steps of the experiment Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 5 of 15 Copyright 2007 © All Rights Reserved One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 Instructional Task Accommodations for Gifted Students: • Create graphs from the data charts and include all possible variables that would affect the rate of predator success and prey success. (i.e. hunting utensil design, camouflage of the beans, and the environment Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 6 of 15 Copyright 2007 © All Rights Reserved One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 Background: Have you eaten yet? (back to general instructions) Natural selection is the main mechanism for evolution. Interactions of populations in communities drive natural selection and provide for species adaptations. However, the ultimate population control is the predator-prey relation ship. One relationship is the cheetah and gazelle predator-prey relationship. The cheetah’s main food source is the gazelle. These animals possess physiological adaptations that help one hunt and the other flee. It should not be surprising that the cheetah and gazelle are the fastest land animals in the world. One individual must hunt for survival and the other must flee for survival. Both organisms must survive and reproduce to send their favorable traits into the next generation. Scientists have determined that these organisms have coevolved in order to sustain the other population. Other traits needed for survival within the phenomenon of predator-prey is the art of mimicry: Mimicry describes a situation where one organism, the mimic, has evolved to share common outward characteristics with another organism. Mimicry helps organism evade predators and helps them survive in order to pass on surviving traits into the next generation. Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 7 of 15 Copyright 2007 © All Rights Reserved One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 Spoon Fork forceps Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 8 of 15 Copyright 2007 © All Rights Reserved Misc. Hunting Area Bean 3 Bean 2 (class data-totals) Bean 3 Bean 2 Bean 1 (class data-totals) Bean 3 Bean 2 (class data-totals) Concrete Hunting Area Bean 1 Grassy Hunting Area Bean 1 Bean 3 Bean 2 Bean 1 Bean 3 (group data) Bean 2 (group data) Bean 1 (group data) Bean 2 Misc. Hunting Area Bean 2 Concrete Hunting Area Bean 1 Grassy Hunting Area One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 Bean Types that survived Grassy Environment Concrete Environment Miscellaneous Environment Group Group Group Class Class Bean Type 1 Bean Type 2 Bean Type 3 Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 9 of 15 Copyright 2007 © All Rights Reserved Class One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 Extension Activity: Sickle Anemia Genetics & Natural Selection Lab (back to general teacher instructions) Teacher notes: Use this activity to apply how the environmental pressures of malaria can increase the incidence of sickle cell trait in the human populations. This activity will review and emphasize the flow of biological information (DNA RNAProtein Trait) as well as showing the mutation responsible for expressing the sickle cell shape. The teacher should use this extension activity as a scaffolding lesson by threading genetics into natural selection. Background Teacher note: Use the pictures to assess prior knowledge of how a mutated trait, such as sickle cell anemia could occur. It is helpful to have students understand the term anemia to appreciate the magnitude of this trait on health an on survival against malaria. Teachers could use a TChart to address the PROS and CONS of having this disorder. The overall outcome of this extension activity is to help students connect that the traits most favorable for survival are determined by environmental pressures such as parasites, disease, predator prey relationship, and other environmental pressures. Abnormal Normal Genetics of Sickle Cell Anemia Sickle cell anemia was the first genetic disease to be characterized at the molecular level. The mutation responsible for sickle cell anemia is small? Just ONE nucleotide of DNA out of the three billion in each human cell causes this trait to be expressed. Yet it is enough to change the chemical properties of hemoglobin, the iron and protein complex that carries oxygen within red blood cells. Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 10 of 15 Copyright 2007 © All Rights Reserved One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 There are approximately 280 million hemoglobin molecules in each red blood cell (RBC). The protein portion of hemoglobin consists of four globin subunits (amino acid units): While the binding of oxygen actually occurs at the iron sites, all four globin chains (amino acid) must work together in order for the process to function well. Part 1 Research the PROS and CONS of sickle cell anemia: List as many thoughts as possible in the chart below: Suggested Article: July 2007 article on Malaria Malaria: Stopping a Global Killer. http://www7.nationalgeographic.com/ngm/0707/feature1/index.html What are PROS of having sickle cell anemia as a disorder? What are CONS of having sickle cell anemia as a disorder? Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 11 of 15 Copyright 2007 © All Rights Reserved One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 In the United States, about 1 in 500 African-Americans develops sickle cell anemia. In Africa, about 1 in 100 individuals develops the disease. Why is the frequency of a potentially fatal disease so much higher in Africa? Answer Below. Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 12 of 15 Copyright 2007 © All Rights Reserved One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 Part 2: Transcription and Translation of cellular information. 1. What does this word equation mean? DNA RNA Protein Trait 2. Sickle Cell at the Molecular Level (please use a genetic code chart to decode the biological information from DNA to trait) In sickle cell anemia, there is a mutation in the gene that encodes the chain of hemoglobin. Within this gene (located on Chromosome 11), ONE BASE in the DNA is replaced with another base, and this mutation causes the normal amino acid #6 to be replaced by another amino acid. A: Making a Normal Beta Chain of Hemoglobin The sequence below is the first part of the DNA sequence for a chain of normal hemoglobin. Fill in the complementary DNA strand using the base-pairing rules for making DNA (A pairs with T, C pairs with G). Parent Strand DNA: GTG CAC CTG ACT CCT GAG GAG New Complementary Strand Fill in the correct sequence. Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 13 of 15 Copyright 2007 © All Rights Reserved One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 Now make the messenger RNA from the new complementary strand of DNA that you just wrote down. Use the RNA basepairing rules (same as DNA but use U instead of T). mRNA Strand Now, using the Genetic Code chart in your textbook, translate this mRNA into a sequence of amino acids. Amino acid chain B. Making Sickle Cell Hemoglobin In sickle cell anemia, there is a mutation at the seventeenth nucleotide of DNA in this gene; the nucleotide is changed from A to T. Fill in the complementary DNA strand, mRNA, and amino acid sequence in the hemoglobin protein to simulate the seventeenth mutation. Parent Strand GTG CAC CTG ACT CCT GTG New Complementary Strand mRNA Strand Amino acid Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 14 of 15 Copyright 2007 © All Rights Reserved GAG One Stop Shop For Educators Georgia Performance Standards Framework for Biology 9-12 3. Problem Based Learning Questions: A: Mice that have been genetically engineered to contain a defective human hemoglobin gene have symptoms typical of sickle cell anemia, making them an ideal model for laboratory experimentation. In 2000, these mice were mated to another genetically engineered mouse line expressing human fetal hemoglobin. When compared to their sickle cell parents, the offspring had greatly reduced numbers of abnormal and sickled RBCs, increased numbers of RBCs overall (reduced anemia), and longer lifespans. What basic principles of genetics would scientist need to understand the outcome of this particular experiment? How would this experiment best help scientist understand the mechanism of natural selection on genetic traits in the environment? B: Indian and Saudi Arabian people have a milder variation of sickle cell anemia, sometimes with no symptoms. In this population twenty-five percent of each person’s hemoglobin is the fetal kind. Similarly, the blood of adults with an inherited condition called "hereditary persistence of fetal hemoglobin" also contains fetal hemoglobin and these individuals are healthy. Some people with this condition completely lack adult hemoglobin and still show no ill effects. Biochemical experiments have demonstrated that, in a test tube, fetal hemoglobin inhibits polymerization (linking of amino acid chains) of sickle cell hemoglobin. Using this word equation ( the biological flow of cellular information): DNARNAProteinTrait why is it that some adults in India and Saudi Arabia continue to express fetal hemoglobin? Explain why some symptoms of sickle cell anemia are exhibited in these individuals? Teacher Resources: Adapted from Genetics Education Partnership. A simulation lab could be used from this source to teach how natural selection shapes allelic frequency. The background and PBL questions in this task were modified from this resource. http://genetics-education-partnership.mbt.washington.edu/class/activities/HS/sickle-bean.htm July 2007 article on Malaria Malaria: Stopping a Global Killer. http://www7.nationalgeographic.com/ngm/0707/feature1/index.html Georgia Department of Education Kathy Cox, State Superintendent of Schools Biology 9-12 Equilibrium August 17, 2007 Page 15 of 15 Copyright 2007 © All Rights Reserved
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