Early Careers for Biomedical Scientists: Doubling (and Troubling) Outcomes Paula Stephan [email protected] Georgia State University February 26, 2007 Overview • Throughout 1990s concern expressed regarding workforce outcomes for early career biomedical scientists • In late 1990s, NIH budget began an expansion that resulted in a doubling of the budget over a 5-year period • Here we examine the effects of this doubling on careers of young life scientists Overview continued • Begin by discussing why the young are of special interest • Continue by summarizing the early career situation for biomedical scientists in the 1990s. • Update the situation, for 2003 and 2005. • Examine NIH funding patterns during and after the doubling • Conclude with a summary and discussion of what the future may hold Acknowledgements/Caveats • Portion of presentation uses data from Survey of Doctorate Recipients. Use of data does not imply NSF endorsement of research methods or conclusions. • SDR data are for PhDs who received their doctoral training in U.S.; includes MD/PhDs; fails to count those who received PhD training outside the U.S. • Views expressed are not those of NIH • Acknowledge support from the Science and Engineering Workforce Project funded by Alfred P. Sloan Foundation. Why Focus on the Young? • Relationship of age to productivity • Cohort effects: initial labor market conditions when one gets a PhD have impact throughout career • Young have been drawn to study biomedical sciences because of a love of science…highly motivated • Efficiency concerns—is this a rational policy? • Signals created by poor prospects affect future flows into PhD programs Situation in 1990s • In 1996 NRC established a committee to study trends in the early careers of life scientists. • Rationale for study was that production of PhDs had been growing but job market outcomes had not. Manifested by such indicators as – Increase in time to degree – Increase in number holding postdoc position and length of postdoc position – Decrease in probability of holding a tenure track position – Decline in NIH support for young investigators NRC Committee • Chaired by Shirley Tilghman, Currently President of Princeton Numbe r o f P h.D .s C o nfe rre d in the B io me dic a l S c ie nc e s 1 9 6 3 -1 9 9 6 7200 4800 3600 2400 1200 95 19 93 19 91 19 89 19 87 19 85 19 83 19 81 19 79 19 77 19 75 19 73 19 71 19 69 19 67 19 65 19 63 0 19 T otal Ph.D .s 6000 Y ears Num b e r o f P h.D .'s Source: NRC Report Median Time to Degree and Age at Degree 8.5 (US Life-Science Ph.D.s in the Biom edical Sciences) 32 8 7.5 31 T im e to D egree 7 30.5 6.5 6 30 5.5 29.5 5 M edian Age at T im e of Degree 31.5 29 4.5 4 28.5 1970 1971 1972 1973 1974 1975 1976 1977 1978 1979 1980 1981 1982 1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 Year Time to Degree Median Age at Time of Degree Source: NRC Report Percen t o f U S L ife-Scien ce P h .D .s in th e Bio m ed ical Scien ces Plan n in g Po st D o cto ral T rain in g U p o n G rad u atio n 65 60 55 P ercent 50 45 40 35 30 25 20 1963 1964 1965 1966 1967 1968 1969 1970 1971 1972 1973 1974 1975 1976 1977 1978 1979 1980 1981 1982 1983 1984 1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 Ye a r P o std o cto ra l A p p o intm e nts Source: NRC Report F ractio n o f B io m ed ical L ife S cien ce D o cto rates in P o std o cto ral A p p o in tm en ts in A cad em e, In d u stry, an d G o vern m en t (1973-1995) 70 60 P ercent 50 40 30 20 10 0 1-2 Y ears S inc e P h.D. 3-4 Y ears S inc e P h.D. 5-6 Y ears S inc e P h.D . In te rv ie w D a te 1973 1977 1981 1985 1989 1993 1995 Source: NRC Report Percent of B iom edical Life Science Ph.D .s in Selected Sectors (5-6 Years Since D egree) 50 45 40 35 P ercent 30 25 20 15 10 5 0 Tenure-Trac k Tenure-Trac k Fac ulty Pos ition at Fac ulty Pos ition at Indus try PhD Ins titutions Other Ins titutions Federal Labs and E mployment S ector 1973 1977 Other Other Gov ernment 1981 1985 1989 1993 1995 Source: NRC Report Nu m b er o f Bio m ed ical L ife S cien ce P h .D.s in S elected S ecto rs (56 Years S in ce Deg ree) 3000 2500 Num ber 2000 1500 1000 500 0 Tenure-Trac k Tenure-Trac k Fac ulty Pos ition at Fac ulty Pos ition at PhD Ins titutions Other Ins titutions Indus try Federal Labs and Other Other Gov ernment E m p lo y m e n t S e c to r 1973 1977 1981 1985 1989 1993 1995 Source: NRC Report P ercen t o f B io m ed ical L ife S cien ce P h .D .s in P art-tim e, T em p o rary P o sitio n s o r U n em p lo yed (5-6 Y ears S in ce R eceip t o f P h .D .) 35 30 P ercent 25 20 15 10 5 0 1973 1977 1981 1985 1989 1993 1995 S u rvey Year P ostdocs E m ployed P art-tim e Unem ployed and S eeking Other A cadem ic P ositions Data: NRC Report Percent of Life-Science Ph.D.s in Selected Sectors (56 Years Since Degree) 1973 and 1995 by Ranking of Institution 60 50 Percent 40 30 20 10 0 Tenure-Track Faculty P os ition at P hD Institutions Quality Institutions (1973) Tenure-Track Fac ulty P osition at Other Institutions Quality Ins titutions(1995) Indus try Federal Labs and Other Governm ent Other Interview Date S eries5 Other Ins titutions (1973) Other Ins titutions (1995) Data: NRC Report NIH Support For those 35 and Younger • • • • • • • 1993 about 380 awards 1994 about 410 awards 1995 about 350 awards 1996 about 340 awards 1997 about 330 awards 1998 about 330 awards Average age at first independent award in 1980: 37; average age in 1990 39.5. Continued to rise during 1990s. Summary of Recommendations of NRC Committee • Restraint of the Rate of Growth of the Number of Graduate Students in the Life Sciences • Dissemination of Accurate Information on the Career Prospects of Young Life Scientists • Improvement of the Educational Experience of Graduate Students • Enhancement of Opportunities for Independence of Postdoctoral Fellows • Alternative Paths to Careers in the Life Sciences Post Report Situation • NIH budget doubled • Number of PhDs residing in U.S. who trained in U.S. aged 35 or younger increased; postdocs trained outside the U.S. also increased. • Hiring patterns of U.S. trained changed somewhat, with a lag • See this by looking at NSF data and at AAMC Faculty Roster Data NIH Budget BUDGET AUTHORITY FY 1977 – FY 2007 (Current vs. Constant 1977 Dollars Using BRDPI as the Inflation Factor)(Dollars in Billions) $30 $25 $20 $15 $10 $5 $0 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981 1979 1980 1978 1977 Current Dollars Constant Dollars OER: NIH Budget over time Biomedical PhDs Trained in U.S. Age 35 or Younger 20,000 Number 15,000 10,000 5,000 0 1993 1995 1997 1999 Year Age 35 or Younger Source: Survey of Doctorate Recipients, NSF. The use of NSF data does not imply NSF endorsement of the research methods or conclusions contained in this report . 2001 2003 Biomedical PhDs Trained in U.S. Age 35 or Younger 20,000 Number 15,000 10,000 5,000 0 1993 1995 1997 1999 2001 Year Age 35 or Younger In Tenure-track Jobs Source: Survey of Doctorate Recipients, NSF. The use of NSF data does not imply NSF endorsement of the research methods or conclusions contained in this report . 2003 Conclude • Number of tenure track positions occupied by those trained in the U.S. 35 and younger held constant at best until 2001; then grew somewhat towards end of NIH doubling. • Probability that a young person trained in biomedical life sciences in U.S. holds a tenure track position is about the same in 2003 as it was in 1993 and improved between 2001 and 2003: 10.3 % to 10.4% (or from 6.9% in 2001). • Next slides show that – postdoc situation also improved; – non-tenure track positions grew during the period Percentage Proportion of Biomedical PhDs Trained in U.S. in Postdoc Positions By Time Since Degree 70 60 50 40 30 20 10 0 1993 1995 1997 1999 2001 2003 Year 0-2 Years 3-4 Years 5-6 Years 7-8 Years Source: Survey of Doctorate Recipients, NSF. The use of NSF data does not imply NSF endorsement of the research methods or conclusions contained in this report. Over 8 Years Labor Force Status of Biomedical PhDs Trained in U.S. Age 35 or Younger in Other than Tenure-Track Positions Number 18,000 16,000 Unemployed & Out of the Labor Force 14,000 12,000 10,000 8,000 6,000 4,000 PT Employed Other FT Employed Postdoc 2,000 0 1993 Not Tenure-track 1995 1997 1999 2001 2003 Year Source: Survey of Doctorate Recipients, NSF. The use of NSF data does not imply NSF endorsement of the research methods or conclusions contained in this report. Labor Market Outcomes in the Biomedical Sciences Across Age Groups • • • • Tenure track by age Full-time employment by sector Tenure-track status in academe Labor force status Tenure Track Biomedical Faculty by Age 35,000 30,000 G 55 25,000 51-55 20,000 46-50 15,000 41-45 10,000 35-40 5,000 LE 35 0 1993 1995 1997 1999 2001 2003 Tenure track status is for those trained in U.S. Source: Survey of Doctorate Recipients, NSF. The use of NSF data does not imply NSF endorsement of the research methods or conclusions contained in this report. Labor Force Status: Biomedical PhDs 140000 120000 Unemployed/Out of Labor Force 100000 Part Time 80000 Full time not university 60000 40000 Post doc 20000 0 Total Academe 1993 1995 1997 1999 2001 2003 Labor force Status for those trained in the U.S. Source: Survey of Doctorate Recipients, NSF. The use of NSF data does not imply NSF endorsement of the research methods or conclusions contained in this report. Full Time Positions by Sector: Biomedical Sciences 120000 100000 80000 Full time not university Post doc Total Academe 60000 40000 20000 0 1993 1995 1997 1999 2001 2003 Slide shows positions for those trained in the U.S. Source: Survey of Doctorate Recipients, NSF. The use of NSF data does not imply NSF endorsement of the research methods or conclusions contained in this report. Summary • Growth in non-academic sector jobs has outpaced growth in academic sector jobs during the period for those trained in the United States. • Growth in those unemployed or out of the labor force • Decline in percent in post doc positions from 13.3% to 9.7% Tenure Track Status: Biomedical Sciences 50000 45000 40000 35000 30000 total-non-tenure track Total tenure-track 25000 20000 15000 10000 5000 0 1993 1995 1997 1999 2001 2003 Slide shows tenure tract status for those trained in the United States. Source: Survey of Doctorate Recipients, NSF. The use of NSF data does not imply NSF endorsement of the research methods or conclusions contained in this report. Summary • Growth in academic positions for those trained in the United States during past 10 years of about 33% • Growth is noticeable during NIH-doubling period • Growth has been heavily concentrated in the non-tenure track positions – Non-tenure track has grown by over 70% – Tenure-track has grown by 20% Medical Colleges vs. Non-medical Colleges • Next slides show that – Growth has been in medical colleges – Especially among non-tenure track positions Academic Positions by Sector 25000 20000 15000 total medical total non-medical 10000 5000 0 1993 1995 1997 1999 2001 2003 Slide shows positions held by those trained in the United States. Source: Survey of Doctorate Recipients, NSF. The use of NSF data does not imply NSF endorsement of the research methods or conclusions contained in this report. Medical Faulcy Positions by Tenure Track, Biomedical Sciences 25000 20000 15000 Non Tenture Track Tenure Track 10000 5000 0 1993 1995 1997 1999 2001 Slide is for those trained in the U.S. Source: Survey of Doctorate Recipients, NSF. The use of NSF data does not imply NSF endorsement of the research methods or conclusions contained in this report. 2003 Summary • See growth in hiring of individuals trained in the U.S. among medical colleges during the decade relative to non-medical colleges • Change in mix of tenure and tenure track – 33% of medical faculty were in non-tenure track positions in 1993; – 45% were in non-tenure track positions in 2003. • Considerable growth in hiring at medical colleges during the NIH doubling period Non Tenure Track Positions, Biomedical Sciences, Medical Schools 12000 10000 8000 Other Not TT Full Not TT Associate Not TT Assistant Not TT 6000 4000 2000 0 1993 1995 1997 1999 2001 2003 Slide is for those trained in the U.S. Source: Survey of Doctorate Recipients, NSF. The use of NSF data does not imply NSF endorsement of the research methods or conclusions contained in this report. Non Tenure Track Positions, Biomedical Sciences, Medical Schools 5000 4500 4000 3500 3000 Assistant Not TT Associate Not TT Full Not TT Other Not TT 2500 2000 1500 1000 500 0 1993 1995 1997 1999 2001 2003 Slide is for those trained in the U.S. Source: Survey of Doctorate Recipients, NSF. The use of NSF data does not imply NSF endorsement of the research methods or conclusions contained in this report. Other Data Indicators • AAMC Faculty Roster Data • Bricks and Mortar 19 80 19 81 19 82 19 83 19 84 19 85 19 86 19 87 19 88 19 89 19 90 19 91 19 92 19 93 19 94 19 95 19 96 19 97 19 98 19 99 20 00 20 01 20 02 20 03 20 04 Number First Assistant Professorship: Medical Schools 6000 5000 4000 3000 MD-PhD PhD MD 2000 1000 0 Year AAMC Data Average Age at Tim e of First Assistant Professorship at US Medical Schools AAMC Faculty Roster Data as of March 31, 2006 42 41 40 39 38 37 MD/PhD PhD 36 MD 35 34 33 19 80 19 81 19 82 19 83 19 84 19 85 19 86 19 87 19 88 19 89 19 90 19 91 19 92 19 93 19 94 19 95 19 96 19 97 19 98 19 99 20 00 20 01 20 02 20 03 20 04 20 05 32 AAMC Data Faculty Medical Schools: Basic Sciences 8000 7000 6000 5000 physiology microbiology Biochemistry 4000 3000 2000 1000 0 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 AAMC Data S&E Research Space: Academic Institutions 40 35 Net Assignable Sq. Ft. (millions) 30 Agricultural sciences Biological sciences Computer sciences Earth and Ocean Engineering Mathematics Medical sciences Physical sciences 25 20 15 10 5 0 1988 1990 1992 1994 1996 Year 1998 1999 2001 2003 New Construction • NSF reports greatest number of institutions began construction in fields of biological and medical sciences in FY2002 or FY2003. • 56% of newly constructed space to be used for these 2 fields Appears to be good news for early career biomedical scientists • • • • • • Age of first assistantship fell for first time in 2003 Jobs on an increase (or were). But SDR data is already out of date The pickup was relatively modest for the young. Even in the best of times fewer than one-in seven of young biomedical PhDs have an academic appointment (tenure-track or non-tenure track). Hiring was concentrated in non-tenure track positions. The pickup that occurred was fueled in part by new buildings coming on line which in turn were fueled by NIH budget growth. Lagged the doubling. But… Jobs come with high expectations • • • • • Faculty expected to generate grants Not new, but more and more frequently this is a condition of employment. Three years to cover salary. Many tenure-track positions paid out of soft-money Not one grant or two grants but three became expectation at many research institutions Not surprising that – – Number of NIH applications on increase Many established investigators increased their number of grants and size of their labs. NIH Situation • • • • • • Budgets have been flat, growing at less than inflation. From $27.2 billion in 2003 to $28.7 in 2006. Costs of grants are rising Results in more grant applications chasing constant to declining pool of resources Translates into lower success rates Most applications come from individuals who already have grants. New investigator pool is on decline after peeking in 2003. NIH Primer • R01 is basic grant for independent research; in earlier years R29 existed as the “first” independent award for new investigators. Duration of three to five years. • Type 1 is a new application • Type 2 is a continuing application • Type 1’s can be from “new” investigators who have never been funded or from established investigators • Review process: triage—group that is not scored; possible to submit up to two amendments; can resubmit even if not scored. • Important to distinguish between applicants and applications Number of NIH Competing R01 Equivalent* Applications, Awards and Percent Funded (Success Rate) 30 35% 20% 15 15% 10 10% 5 5% 20 05 20 04 20 03 20 02 20 01 20 00 19 99 19 98 19 97 0% 19 96 - 19 95 (in Thousands) Number of Applicatio 25% 20 Fiscal Year Reviewed Awarded Success Rate NIH, OER: “Investment…” R01 Equivalent* Includes R01, R23, R29 and R37 Percent Funde 30% 25 Number of NIH Competing R01 Equivalent* Applicants Reviewed, Awarded, and Percent Funded (Success Rate) 25 40% 35% 30% 25% 15 20% 10 15% 10% 5 5% - 0% 95 19 96 19 97 19 98 19 99 19 01 20 00 20 02 20 03 20 04 20 05 20 Fiscal Year Reviewed Awarded Percent Funded R01 Equivalent* Includes R01, R23, R29 and R37 NIH, OER: “Investment…” Percent Funde Number of Applica (in Thousands) 20 NIH COMPETING R01 EQUIVALENT APPLICATIONS BY YEAR OF REVIEW NIH Competing R01 Applications by Year of Review 18,000 16,000 14,000 12,000 10,000 8,000 6,000 4,000 2,000 06 20 05 20 04 20 03 20 02 20 01 20 00 20 99 19 98 19 97 19 96 19 95 19 94 19 93 19 92 19 91 19 19 90 0 Review Year Original New Applications Original Competing Continuations Amendments to New Applications Amendments to Competing Continuations NIH, OER for AIRI Number of New and Established Investigators Receiving Competing and R01 and R01 Equivalent Grants to 1962 to 2004 8,000 40% Established Investigators New Investigators Percent New Investigators Fiscal Year NIH, OER for AIRI 04 20 02 20 00 20 98 19 96 19 94 19 92 19 90 19 88 19 19 19 19 19 19 19 19 19 19 19 19 19 86 0% 84 0 82 5% 80 1,000 78 10% 76 2,000 74 15% 72 3,000 70 20% 68 4,000 66 25% 64 5,000 62 30% Percent Grants to New Investigators 35% 6,000 19 Number of Grants 7,000 NIH New (Type 1) Competing R01 Equivalent Applications Success rates for first time and previously funded investigators 35% 30% 28.3% 28.7% 28.1% 27.0% 26.9% 26.9% 25.4% 25% Success Rate 23.7% 20% 21.7% 21.3% 20.6% 20.3% 22.5% 21.5% 21.1% 22.2% 21.9% 21.2% 22.5% 20.6% 19.1% 18.4% 18.1% 17.0% 16.8% 15.9% 15% 10% 5% 0% 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 Fis cal Ye ar Previously Funded Investigators First Time Investigators R01 Equivalent = R01, R29, and R37 activities . NIH, OER for GREAT 2004 Number of Different NIH Competing Research Project Grants Awarded to New Investigators, FY 1962 - 2005 3000 2000 1500 1000 500 20 04 20 02 20 00 19 98 19 96 19 94 19 92 19 90 19 88 19 86 19 84 19 82 19 80 19 78 19 76 19 74 19 72 19 70 19 68 19 66 19 64 0 19 62 Number of Awards to New Investigators 2500 Fiscal Year R01 R23 R29 R03 R21 Other NIH, OER for GREAT New Investigator Situation – Virtually no increase in funding of “new” investigators in traditional R01 – Growth for new investigators has been in the R03 and R21 which are small in terms of funding and length of award. • R03—small research project-- $50,000 per year for two years; • R21 investigator-initiated exploratory development research—up to two years, not to exceed $275,000). NIH Support Of First Time Investigators 2000 NIH Competing R01/R29 awards to individuals without prior research grant support 2002 1407 1439 1511 1532 73 69 1492 1492 2005 1559 98 90 2004 Post Doubling 1543 76 2000 66 1999 80 73 65 1998 Period of Doubling 69 1200 1000 600 1353 1284 1996 800 1995 Pre-doubling 1643 400 200 0 Fiscal Year Other 2003 Number of Awards 1400 88 1997 1600 2001 1800 AIRI NIH, OER for AIRI AVERAGE AGE OF COMPETING R01 EQUIVALENT AWARDEES Average Age of Competing R01 Equivalent Awards 55 51.7 45 43.2 40.9 42.9 40 37.3 35 35.2 Average Age of New investigators Average Age of All investigators NIH, OER for AIRI 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 1981 1980 1979 1978 1977 1976 1975 1974 1973 1972 1971 30 1970 Agerage age 50 DISTRIBUTION OF INVESTIGATOR AGES NIH Competing R01 Equivalent Awardee 14.5% 14.6% 20.8% 24.9% 19.0% 6.2% 1995 15.8% 15.2% 20.3% 23.9% 18.4% 17.0% 14.6% 20.3% 24.6% 17.1% 17.9% 15.7% 20.5% 23.1% 16.5% 19.6% 16.4% 21.4% 22.4% 21.7% 22.7% 23.9% 24.9% 27.5% 27.6% 16.6% 16.3% 16.0% 17.4% 18.1% 18.2% 21.1% 21.1% 22.2% 19.6% 22.1% 21.4% 21.7% 21.7% 21.7% 20.9% 20.0% 20.1% 15.6% 14.1% 13.8% 13.0% 13.1% 12.9% 12.0% 4.0% 3.8% 4.5% 3.5% 3.8% 3.4% 2000 2001 2002 2003 2004 6.4% 6.4% 6.2% 4.8% 1996 1997 1998 1999 Fiscal Year 35 and Younger 36 - 40 41 - 45 46 - 50 51 - 55 Over 55 NIH, OER for AIRI 2005 Summarize NIH Data During Doubling • Tremendous increase in number of new R01 applications • Majority come from established investigators • Number of established investigators receiving R01s has increased dramatically • Increase in percent of investigators who have more than one grant • Creates significant change in age-distribution of NIH awardees Kangaroo Solution? • Pathway to Independence Award Program: K99/R00 • 150 to 200 postdoctoral candidates for each of next 5 years. • Mentored support while post doc followed by 3 years of R01-level funding, contingent upon securing a tenure-track position with appropriate institutional support and resources. • A program with unintended consequences? Program came out of the NRC Committee Report: Bridges to Independence Summary • During doubling – New grants to established investigators have increased dramatically. – Virtually no increase in funding of “new” investigators in traditional R01 – Growth for new investigators has been in the R03 and R21 which are small in terms of funding and length of award. – NIH increasingly is supporting established, older investigators. – Small number of Kangaroo awards means that implementation will have little effect on age distribution. – Success rates for R01s are declining; – Success rates are especially low for new investigators. – Increased proportion of applications are being triaged and thus do not receive comments. – Speed up review process as a solution? – Bridge money is being sought from universities. What does future hold? • Assuming NIH situation stays as is • Universities will have to find alternative ways to pay for buildings. NIH pick up less of tab; some relief as early-funded R01s lapse • NIH is beginning to put brakes on tuition increases which universities relied on • Recent faculty hires will have an especially difficult time getting funding and staying funded. • Bridge money is constrained. Labs will downsize. Staff will be laid off. • Young and untenured will bear disproportionate share of adjustment costs. Future continued . . . • Jobs, especially tenure-track jobs, are unlikely to increase • Young researchers will increasingly need to look for alternative places to do research • Unclear whether jobs in industry will expand sufficiently to absorb these young researchers Lessons/Questions • Fallacy of composition • Even in the best of times, the young don’t benefit that much from increases in funding • Soft landing? • Do additional grants for productive scientists significantly contribute to scientific knowledge? • Time to rethink the way in which research labs are staffed in the United States?
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