TechnologyTransferInitiative BenchmarkingTechTransferSummary November2015 DavidL.Gulley,PhD Director,TechnologyTransferOffice TableofContents Introduction 1. AcademicInstitutions...............................................................................................................1 1.1. R&DExpendituresforHigherEducationInstitutionsinPuertoRico................................1 2. TechnologyTransferMetrics....................................................................................................3 2.1. PeerSelection...................................................................................................................4 2.2.R&DExpenditures.............................................................................................................5 2.3. TTOStaffing.......................................................................................................................6 2.4.Disclosures,Licensing,andLicenseIncome.......................................................................7 2.5.LegalFeesandPatenting..................................................................................................9 2.6.PatentProtectionandPatentsIssued.........................................................................10 2.7.Start-ups.........................................................................................................................12 PuertoRicoScience,TechnologyandResearchTrust TechnologyTransferInitiative BenchmarkingTechTransferSummary November2015 Introduction ThePuertoRicoScience,TechnologyandResearchTrust(Trust)TechnologyTransferinitiativeis aimed at designing, creating and implementing an agile and effective structure to foster the commercializationoflocallydevelopedscientificinventionsanddiscoveries. Through this initiative the Trust seeks to establish a Technology Transfer Office (TTO) that servesasanumbrellaentitytomoveinnovationsfromacademiatotheprivatesector.Thegoal ofthisTechnologyTransferinitiativeisthecreationofnewproductsandcompanies,expansion ofemployment,andfuelingeconomicactivityinPuertoRico. Benchmarking academic institutions and their technology transfer performance and opportunitiesrequiresadetailedunderstandingofthreeareas: • research&developmentperformance, • technologytransfermetrics,and • theuseofbestpractices This benchmarking document presents technology transfer metrics and the use of best practices.Research&developmentbenchmarkingispresentedseparately. 1. AcademicInstitutions ResearchanddevelopmentexpendituresarereportedannuallybyeachinstitutiontotheU.S. National Science Foundation and reported by the NSF National Center for Science and EngineeringStatisticsinanannualHigherEducationResearchandDevelopmentSurvey.Only those individual campuses reporting to NSF are included. The latest data available is FY2013 (July2013-June2014).Summarytablesarepresentedthataggregateinformationfor: • UniversityofPuertoRicoSystem(UPR)campuses - Mayagüez,MedicalSciences,andRioPiedras • AnaG.MéndezUniversitySystem(SUAGM)campuses - Metropolitana,Turabo,anddelEste • PonceHealthScienceUniversity(PHSU) • UniversityCentraldelCaribe(UCC) 1.1. R&DExpendituresforHigherEducationInstitutionsinPuertoRico Research and development at institutions of higher education provide researchers with the BenchmarkingTechTransferSummary November2015 1 fundsnecessarytopursuenewknowledge,addressspecificorbroadissues,andmakethatnew knowledge and those solutions available to their scientific colleagues, the private sector, and thepublic. To facilitate this transfer of knowledge, publication in academic journals and presentation at academic conference are encouraged and key to making the results widely available. As the result of the U.S. Bayh-Dole Act (Pub.L. 96-517, 1980) universities and their researchers have beenincentivizedtoalsotransfertheresultsoffederallyfundedresearchtotheprivatesector through a technology transfer process that involves the protection (e.g., patenting) and licensing of intellectual property. As a result, technology transfer offices were established in universities and a new profession emerged that links science to business, with the goals of developingnewproductsandprocessesandbenefittingthepublicatlarge. Five-YearTrends Puerto Rico’s universities compete with all U.S. universities for federal funds to support research programs. In 2013, Puerto Rico’s universities spent1$140 million on research and development, a 23% increase over a five-year period. Expenditures from the one-time AmericanRecoveryandReinvestmentActof2009(ARRA)havedecreasedthrough2013. The public University of Puerto Rico System (UPR) consistently achieved the highest ranking, producing about 75% of all R&D expenditures at Puerto Rico’s universities. In addition, its expendituresincreasedfrom$97.9millionin2009to$105millionin2013,a7%increase.The most rapid increases in R&D expenditures were from the Ana G. Méndez University System (SUAGM),from$1.7millionto$16.3million,andthePonceHealthSciencesUniversity(PHSU), from$7.1millionto$12.3million,whileUniversidadCentraldelCaribe(UCC)showedaslight decline. 1 R&Ddataismeasuredby“expenditures”,i.e.,thefundsactuallyspentonresearch. BenchmarkingTechTransferSummary November2015 2 2. TechnologyTransferMetrics The protection of intellectual property (IP) is fundamental in attracting private sector businesses,entrepreneursandinvestors.Businesses(licensees)desireacompetitiveadvantage throughalicensethattransfersrightstoexploittheIP.WithoutIPprotection,discoveriesand inventions may be publicly available through publication in journals, presentations at conferences,orothermethodsofpublicdisclosure. Thegoalofatechnologytransferofficeistoworkcloselywithresearcherstofacilitatetimely disclosureofpotentialinventions.Therearethreekeystoaneffectiverelationship: • Educateresearchersabouthowtorecognizearesearchdiscoveryandwhentodisclose thefindingstothetechnologytransferoffice. • Synchronize the filing of IP protection/patents so as not to impede the researchers abilitytopublish. • Build confidence in the researchers the technology transfer process will be robust, unbiased,andtimely. Benchmarking technology transfer metrics of Puerto Rico’s higher education institutions can clarify past efforts, but most importantly build an effective approach to a future Technology TransferOffice(TTO).WhiletheUPRSystemhasahistoryofIPprotectionthroughitsOfficeof IntellectualPropertyandCommercialization,itslicensing(transfer)effortshaveproducedfew licensesandnotbeenthemainfocusofactivitytodate.AtthistimetheUPR,SUAGM,PHSU, andUCCallhaveindividualsservinginrolesthatcanfacilitatetechnologytransfer. Withtheuniversities’R&Dprofiles,howshouldaTTObestructuredandresourced? Arationalbusinessapproachistobenchmarkpeerhighereducationinstitutionswithasimilar R&Dprofileandusestandardtechnologytransfermetricsasfuturebenchmarks. TheAssociationofUniversityTechnologyManagers(AUTM)isanon-profitassociationof3,200 individual members who work in academic, research, government, legal and commercial settings. AUTM promotes and supports technology transfer through education, advocacy, networking and communication. Each year, AUTM conducts its Licensing Activity Survey to quantify tech transfer and for more than two decades, has been the leader in collecting, synthesizing,anddisseminatingacademictechnologytransferdata.AUTM’s2013data2isused tocompletethisbenchmarkingsection. The collection of data continues to evolve with the profession. Early numerical measures includedthenumberofpatentsfiled,licenseagreementsexecutedandnewcompaniesformed. Laternumericalmeasuresincludedrevenuesfromlicensefees,royaltiesandcashfromequity investments paid to the academic institutions and the numbers of products successfully 2 AUTMLicensingActivitySurveyFY2013http://www.autm.net/FY_2013_Licensing_Activity_Survey/15156.htm BenchmarkingTechTransferSummary November2015 3 introduced to the market. Non-numerical results have also been collected, such as the university's ability to retain entrepreneurial faculty, attract outstanding graduate students, contributetotheinstitutionalreputationforinnovation,augmentitsresearchprogramthrough interaction with the private sector and enhance its reputation for providing highly trained studentstotheworkforce. Thefollowingsectionsinclude: • Peeruniversityselection • R&Dexpenditurecomparisons • Technologytransferstaffing • Disclosures,licensing,andlicenseincome • Legalfeesandpatenting • Patentprotectionandpatentsissued • Start-ups 2.1. PeerSelection A review of the 2013 AUTM Licensing Survey for the U.S. and Canada was completed and includedmetricsandstatisticsfor196technologytransferofficesatuniversitiesandresearch institutes.Fromthisthepeersamplewaslimitedto: • Publicorprivateinstitutionsofhighereducation • Institutionswithmedicalschools • AgroupwithaverageR&DexpenditurecomparabletoPuertoRico’s$140.6million Inthepeergroupthereare15universities,10intheU.S.and5inCanadawithanaverageR&D expenditureof$141.4million,eachwithanoperationaltechnologytransferoffice(TTO). OfnoteistheaverageyeartheTTOwasestablished(1989)whichreflectsthe1980Bayh-Dole ActintheU.S.andthedevelopmentofindustry-liaisonofficesinCanadatofacilitatetechnology transferandindustryengagements. BenchmarkingTechTransferSummary November2015 4 PeerSelectionComparison2013 State/ Province Medical School YearTTO Started Country Univ.ofSaskatchewan SK Yes 1990 Canada $169,940,758 TuftsUniv. MA Yes 1978 USA $163,454,769 GeorgetownUniv. DC Yes 1993 USA $158,889,918 WestVirginiaUniv. WV Yes 1999 USA $151,751,731 OklahomaStateUniv. OK Yes 1995 USA $144,120,753 MedicalCollegeofWisconsinResearchFoundation WI Yes 1984 USA $143,807,297 Univ.ofManitoba MB Yes 1983 Canada $143,759,552 DalhousieUniv. NS Yes 1990 Canada $142,839,369 TempleUniv. PA Yes 1989 USA $136,605,865 TulaneUniv. LA Yes 1985 USA $135,375,143 Univ.ofArkansasforMedicalSciences AR Yes 1994 USA $135,000,000 Univ.deSherbrooke QC Yes 1986 Canada $129,730,364 MemorialUniv.ofNewfoundland NL Yes 1987 Canada $127,980,608 Univ.ofCentralFlorida FL Yes 1985 USA $126,700,000 DrexelUniv. PA Yes 1995 USA $111,043,330 1989 $141,399,964 Institution Average TotalR&D Expenditures Definitions TotalResearchExpenditures:TOTALRESEARCHEXPENDITURESincludeexpenditures(notnewawards)madebytheinstitutioninthesurvey year in support of its research activities that are funded by all sources including the federal government, local government, industry, foundations,voluntaryhealthorganizations(i.e.,AHA,ACS,etc.),andothernonprofitorganizations.Indirectcostsshouldbeincluded. 2.2.R&DExpenditures In comparing peer R&D expenditure sources between federal sources and industry sources, thereareimportantsimilaritiesanddifferences: • Federalsources:61%forpeergroupcomparedto66%forPuertoRico • Industrysources:8%forpeergroupcomparedto2%forPuertoRico ThisdifferenceinindustryengagementpresentsanopportunityforPuertoRico’sinstitutionsto engagetheprivatesector.Aninitialstepmaybetoreviewfacultyincentivesforundertaking sponsoredprojectsandbalancingwithteachingloads.Pastevidenceshowsthereisdisconnect betweenresearchtaxcreditsanduniversityengagement.3 3 GeorgiaTech-PuertoRicoInnovationInstituteforaTechnology-InspiredEconomy,PhaseIIPre-Proposal(2013).PuertoRicoScience, TechnologyandResearchTrustdocument. BenchmarkingTechTransferSummary November2015 5 PeerR&DExpenditureSourceComparison2013 TotalR&D Expenditures Institution Univ.ofSaskatchewan $169,940,758 TuftsUniv. FederalR&D Expenditures $82,253,613 $7,273,619 $163,454,769 $124,973,856 $9,393,514 GeorgetownUniv. $158,889,918 $117,395,509 $5,918,636 WestVirginiaUniv. $151,751,731 $90,832,387 $13,229,297 OklahomaStateUniv. $144,120,753 $44,508,332 $11,349,773 MedicalCollegeofWisconsinResearchFoundation $143,807,297 $115,822,263 $7,648,218 Univ.ofManitoba $143,759,552 $74,657,414 $8,027,349 DalhousieUniv. $142,839,369 $85,990,466 $26,637,803 TempleUniv. $136,605,865 $92,144,866 $6,014,719 TulaneUniv. $135,375,143 $110,935,226 $16,056,874 Univ.ofArkansasforMedicalSciences $135,000,000 NA NA Univ.deSherbrooke $129,730,364 $57,375,196 $8,642,366 MemorialUniv.ofNewfoundland $127,980,608 $42,164,231 $23,024,614 Univ.ofCentralFlorida $126,700,000 $76,500,000 $6,600,000 DrexelUniv. $111,043,330 $88,549,795 $4,605,199 $141,399,964 $86,007,368 $11,030,142 Average IndustryR&D Expenditures Definitions Federal R&D Expenditures: RESEARCH EXPENDITURES: FEDERAL GOVT. SOURCES include expenditures made in the survey year by the institutioninsupportofitsresearchactivitiesthatarefundedbythefederalgovernment.Expendituresbystateandlocalgovernmentsshould beexcluded. IndustryR&DExpenditures: INDUSTRIAL SOURCES include expenditures made in the survey year by the institution in support of its research activitiesthatarefundedbyfor-profitcorporations,butnotexpendituressupportedbyothersourcessuchasfoundationsandothernonprofit organizations. 2.3. TTOStaffing PeerTTOsarematureorganizationsandintegralunitsoftheuniversity.LicensinguniversityIP is one important function, if not the most important. Overall in 2013, the U.S. and Canadian TTOsreported: • $64.2billioninR&D • 2,363FTEstaffofwhich1,118arelicensingand1,245areother Theresultingratiois$27.1millionofR&Dexpenditure/FTE,andtheratiooflicensingstaffto otherstaffisabout1:1.Thesetrendshavebeenconsistentsincethemid1990swithvariations shownintypeofinstitution(e.g.,medicalschools,size,approach).Amongthepeergroupwith anaverageR&Dexpenditure($141.4million)andanaverageof6FTE,theaveragesshow: • TotalTTOStaffing:$23.6millionR&Dexpenditure/FTE BenchmarkingTechTransferSummary November2015 6 • • LicensingFTEs:$35.3millionR&Dexpenditure/FTE OtherFTEs:$70.7millionR&Dexpenditure/FTE Thepeergroupshowsmorelicensingstaff,whichmaybeexplainedbytheapproachtakenby smallerTTOs,wherethoselicensingstaffalsoperform“other”duties. PeerTTOStaffingComparison2013 Institution LicensingFTEs OtherFTEs Univ.ofSaskatchewan 10 3.8 TuftsUniv. 6 1 GeorgetownUniv. 5 4 WestVirginiaUniv. 0 1 OklahomaStateUniv. 5 2 MedicalCollegeofWisconsinResearchFoundation 3 0 Univ.ofManitoba 5 2 DalhousieUniv. 7 3 TempleUniv. 3 1 TulaneUniv. 2 2 Univ.ofArkansasforMedicalSciences 1 3.5 NA NA MemorialUniv.ofNewfoundland 3 1 Univ.ofCentralFlorida 5 6 DrexelUniv. 5 3 4 2 Univ.deSherbrooke Average Definitions Licensing FTEs: Person(s) employed in the TECHNOLOGY TRANSFER OFFICE whose duties are specifically involved with the licensing and patentingprocessesineitherfullorfractionalFTEallocation.Licensingexamplesincludelicenseesolicitation,technologyvaluation,marketing oftechnology,licenseagreementdraftingandnegotiation,andstart-upactivityefforts. OtherFTEs:Person(s)employedintheTECHNOLOGYTRANSFEROFFICEineitherfullorfractionalFTEswhosedutiesandresponsibilitiesareto provideprofessional,administrative,orstaffsupportofTECHNOLOGYTRANSFERACTIVITIESthatarenototherwiseincludedinLICENSINGFTEs. Such duties might include management, compliance reporting, license maintenance, negotiation of research agreements, contract management, accounting, MTA activity, and general office activity. General secretarial/administrative assistance to the TECHNOLOGY TRANSFEROFFICEmayalsobeincludedinthiscategory. 2.4.Disclosures,Licensing,andLicenseIncome Whilepeergrouptechnologytransfermetricsarereadilyavailableandconsistent,PuertoRico’s technology transfer metrics are not publicly available. UPR provides some basic information BenchmarkingTechTransferSummary November2015 7 aboutpatenting,butitisnotup-to-date.TheBenchmarkingBestPractices(surveyandon-site visit,June2015)willcollectmetricsforthoseinstitutionsparticipatingandprovideafoundation forfuturepeercomparisons.Peeraveragesinclude: • 59disclosures, • 9agreements(licensesandoptions),and • agrosslicenseincomeof$3.5million Peeraveragecomparisonsshow: • 1disclosure/$2.4MintotalR&Dexpenditure • 9.8disclosures/FTE,with14.75disclosures/LicensingFTE • 6.5disclosures/agreement • $59,149ingrosslicenseincome/disclosure • $387,755ingrosslicenseincome/agreement It is important to note that the “disclosure to agreement” and “gross license income” comparisonsarenotdirectlyrelatedbutshowanannualtotal. PeerDisclosure,AgreementandIncomeComparisons2013 Invention Disclosures Received Institution LicensesIssued OptionsIssued GrossLicense Income Univ.ofSaskatchewan 42 13 2 $10,035,969 TuftsUniv. 94 5 6 $5,696,395 GeorgetownUniv. 62 1 2 $8,576,039 WestVirginiaUniv. 31 2 1 $159,430 OklahomaStateUniv. 50 10 2 $2,203,775 MedicalCollegeofWisconsinResearchFoundation 42 2 1 $241,547 Univ.ofManitoba 48 6 0 $2,027,238 DalhousieUniv. 44 3 3 $232,111 TempleUniv. 60 4 1 $11,506,822 TulaneUniv. 57 7 2 $3,836,253 Univ.ofArkansasforMedicalSciences 33 4 2 $1,137,124 Univ.deSherbrooke 27 9 0 $5,701,880 MemorialUniv.ofNewfoundland 19 4 1 $89,632 Univ.ofCentralFlorida 124 11 6 $797,883 DrexelUniv. 148 10 14 $104,879 6 3 $3,489,798 Average 59 Definitions InventionDisclosures:INVENTIONDISCLOSURESincludethenumberofdisclosures,nomatterhowcomprehensive,thataremadeintheyear requestedandarecountedbytheinstitution. BenchmarkingTechTransferSummary November2015 8 LicensesandOptions:CountthenumberofLICENSEorOPTIONAGREEMENTSthatwereexecutedintheyearindicatedforalltechnologies. Eachagreement,exclusiveornon-exclusive,shouldbecountedseparately.Licensestosoftwareorbiologicalmaterialend-usersof$1,000or moremaybecountedperlicense,oras1licenseor1/eachforeachmajorsoftwareorbiologicalmaterialproduct(atmanager'sdiscretion)if the total number of end-user licenses would unreasonably skew the institution's data. Licenses for technology protected under U.S. plant patents (US PP) or plant variety protection certificates (U.S. PVPC) may be counted in a similar manner to software or biological material productsasdescribedabove,atmanager'sdiscretion.MaterialTransferAgreementsarenottobecountedasLicenses/Optionsinthissurvey. GrossLicenseIncome:LICENSEINCOMERECEIVEDincludes:licenseissuefees,paymentsunderoptions,annualminimums,runningroyalties, termination payments, the amount of equity received when cashed-in, and software and biological material end-user license fees equal to $1,000ormore,butnotresearchfunding,patentexpensereimbursement,avaluationofequitynotcashed-in,softwareandbiologicalmaterial end-userlicensefeeslessthan$1,000,ortrademarklicensingroyaltiesfromuniversityinsignia.LICENSEINCOMEalsodoesnotincludeincome receivedinsupportofthecosttomakeandtransfermaterialsunderMaterialTransferAgreements. 2.5.LegalFeesandPatenting Legalfeesandpatentingareindicatorsofthelevelofinvestmenttheuniversitymakestoward protectingitsIPandthelegalfeesreimbursedasaresultofsuccessfullicensing.Aswithother technology transfer metrics, these are not available for Puerto Rico institutions but will be includedintheJune2015BenchmarkingBestPracticessurvey. Peeraveragecomparisonsshow: • $15,177inlegalfees/disclosure • 0.89patentapplications/disclosure • $16,895inlegalfees/patentapplication • $313,980inlegalfeesreimbursed/$895,455inlegalfees=35%reimbursementratio, notdirectlycorrelatedtothereportingyear’sfees,butanannualtotal. BenchmarkingTechTransferSummary November2015 9 PeerLegalFeesandPatentingComparisons2013 Invention Disclosures Received Institution LegalFees LegalFees Reimbursed TotalPatent Applications Univ.ofSaskatchewan 42 $628,659 $138,891 25 TuftsUniv. 94 $3,440,801 $1,732,545 127 GeorgetownUniv. 62 $1,409,718 $191,311 76 WestVirginiaUniv. 31 $207,652 0 20 OklahomaStateUniv. 50 $450,482 $270,058 32 MedicalCollegeofWisconsinResearchFoundation 42 $329,012 $196,721 27 Univ.ofManitoba 48 $715,305 $22,121 37 DalhousieUniv. 44 $378,554 $231,628 23 TempleUniv. 60 $651,825 $140,656 47 TulaneUniv. 57 $1,268,381 $600,668 48 Univ.ofArkansasforMedicalSciences 33 $650,923 $456,110 28 Univ.deSherbrooke 27 $232,197 $219,215 0 MemorialUniv.ofNewfoundland 19 $117,512 $11,542 8 Univ.ofCentralFlorida 124 $1,650,000 $176,555 197 DrexelUniv. 148 $1,300,800 $321,673 104 59 $895,455 $313,980 53 Average Definitions LegalFees:LEGALFEESEXPENDITURESincludetheamountspentbyaninstitutioninexternallegalfeesforpatentsand/orcopyrights.These costsincludepatentandcopyrightprosecution,maintenance,andinterferencecosts,aswellasminorlitigationexpensesthatareincludedin everydayofficeexpenditures(anexampleofaminorlitigationexpensemightbethecostofaninitiallettertoapotentialinfringerwrittenby counsel).Excludedfromthesefeesissignificantlitigationexpense,e.g.,anyindividuallitigationexpensethatexceeds5%oftotalLEGALFEES EXPENDITURES.Theyalsodonotincludedirectpaymentofpatentingcostsbylicensees. Legal Fees Reimbursed: LEGAL FEES REIMBURSEMENTS include the amount reimbursed by licensees to the institution for LEGAL FEES EXPENDITURES(seedefinitionforLEGALFEESEXPENDITURES).LEGALFEESREIMBURSEMENTSpaidvialumpsumpaymentsofcostsincurredin prioryearswhenanewlicenseissignedANDregularreimbursementsofnewcostsincurredafterthelicenseissigned.Donotincludeamounts deductedfromLICENSEINCOMEpriortointernaldistributionbecauseLEGALFEESEXPENDITUREShavenotbeenpreviouslyreimbursed(e.g., technologieslicensednon-exclusively.) Total Patent Applications: TOTAL PATENT APPLICATIONS include (1) the first filing of the patentable subject matter (NEW PATENT APPLICATIONS,U.S.orForeign),and(2)U.S.patentcontinuations,divisionals,orreissues,buttypicallydoesnotincludeCIP 2.6.PatentProtectionandPatentsIssued BenchmarkingpatentprotectionandpatentsissuedaregoodindicatorsoftheTTO’spatent strategytoutilizetheU.S.provisional,U.S.non-provisional(utility),foreign(e.g.,PCT),andthe ratioofpatentapplicationstopatentsissued.Patentsissuedmayreflectapatent-granting agenciestrendsaswellasthequalityofthepatentapplication. BenchmarkingTechTransferSummary November2015 10 Peeraveragecomparisonsshow,ofnewpatentapplications: • About70%areforU.S.provisionalpatents • About20%areforU.S.utilitypatents • About10%areforforeignpatents(e.g.,PCTs) Thereisa46%ratioofU.S.utilitypatentapplicationstoU.S.patentsissued,notdirectlyrelated butanannualtotalthatreflectsfilingsfrom3+yearsprior. PeerPatentProtectionandPatentsIssuedComparisons2013 Foreign Patent Applications Provisional Patent Applications Issued US Patents 3 2 17 7 0 0 59 30 40 1 0 39 18 20 15 0 5 5 32 15 1 0 14 12 MedicalCollegeofWisconsinResearchFoundation 27 11 0 0 11 8 Univ.ofManitoba 37 30 3 11 16 9 DalhousieUniv. 23 50 7 27 16 3 TempleUniv. 47 19 0 0 19 9 TulaneUniv. 48 42 3 0 39 4 Univ.ofArkansasforMedicalSciences 28 29 6 3 20 0 Univ.deSherbrooke 0 0 0 0 0 0 MemorialUniv.ofNewfoundland 8 14 4 6 4 1 Univ.ofCentralFlorida 197 96 20 0 76 71 DrexelUniv. 104 95 26 8 61 23 53 36 4 26 13 TotalPatent Applications NewPatent Applications Univ.ofSaskatchewan 25 22 TuftsUniv. 127 59 GeorgetownUniv. 76 WestVirginiaUniv. 20 OklahomaStateUniv. Institution USUtility Patent Applications Average 6 Definitions NewPatentApplications:NEWPATENTAPPLICATIONSFILEDarethefirstfilingofthepatentablesubjectmatter.NEWPATENTAPPLICATIONS FILEDdonotincludecontinuations,divisionals,orreissues,andtypicallydoesnotincludeCIPs.AU.S.PROVISIONALAPPLICATIONfiledinthe surveyyearwillbecountedasnewunlessitisarefillingofanexpiringU.S.PROVISIONALAPPLICATION.IfaU.S.PROVISIONALAPPLICATIONis convertedinthesamesurveyyeartoaU.S.UTILITYAPPLICATION,thenthatcorrespondingU.S.UTILITYAPPLICATIONfiledinthesurveyyear shouldnotbecountedasnew. USUtilityandProvisionalApplications:TOTALU.S.PATENTAPPLICATIONSFILEDincludesanyfilingmadeintheU.S.duringthesurveyyear, includingprovisionalapplications,provisionalapplicationsthatareconvertedtoregularapplications,newfilings,CIPs,continuations,divisionals, reissues,andplantpatents.Applicationsforcertificatesofplantprotectionshouldalsobeincluded.TOTALU.S.PATENTAPPLICATIONSFILED shouldalsoincludePCTapplicationswherethePCTapplicationisthefirstnon-provisionalfilingwheretheU.S.isdesignated.IfaU.S.utility application is filed by entering the national phase of a PCT application in the U.S., that should also be included in TOTAL U.S. PATENT APPLICATIONSFILED.However,aPCTapplicationthatdoesnotdesignatetheU.S.(e.g.,becauseitfollowsapreviousU.S.utilityapplicationoris filedatthesametimeasaU.S.utilityapplication)wouldnotbeincluded. BenchmarkingTechTransferSummary November2015 11 2.7.Start-ups Beginning in the mid 1990s, start-up companies have become increasingly important to technologytransferofficefunctionsandtherelationshiptolocaleconomicdevelopmentefforts. UniversityIPtendstobeveryearlystageandrequiresfurtherdevelopmenttoattractinterest fromlargerestablishedcompanies.Asprivateequityinvestmentintechnologybecamemore common, opportunities to invest early and seek substantial returns also became more common.Universitiesrespondedbychangingpoliciesandpracticestoaccommodatestart-ups. Start-ups are new companies established to develop and commercialize university IP under a license. These start-ups are positioned to raise private funds for early stage development of the IP. Typically, start-ups proceed from an option agreement to a license when university policy and practices guidelines are met. These may include a business plan, identified management (e.g., other than the university employee founder), approved conflict managementplan,andalevelofcommittedfunding. Peeraveragecomparisonsshow: • $70.7millioninR&Dexpenditure/start-upformed(licensed) • 3%ratioofstart-ups/totaldisclosures,notdirectlyrelatedtodisclosuresfromthesame period,butanannualtotal • 33%oflicenseswereforstart-ups,directlyrelatedtothelicenseagreementsexecuted duringtheperiod BenchmarkingTechTransferSummary November2015 12
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