PP41 Different opinions toward salvage prostate brachytherapy: an Uro-GEC Delphi study M. Kaljouw AMC, Amsterdam, the Netherlands Introduction: Despite the effectiveness of radiotherapy to treat prostate cancer, there are still patients that will experience a local relapse. Although data are preliminary, brachytherapy seems an attractive treatment option for recurrent prostate cancer after previous radiotherapy. The UroGEC group of the GEC-ESTRO conducted a Delphi study, to explore the expert’s opinion on the management of salvage prostate brachytherapy (SPB). Methods: For this study, a series of digital questionnaires was send to 33 radiation oncologists and urologists. Selected participants were corresponding authors in published papers on SPB or physicians otherwise closely involved in SPB. The questionnaire comprised three different topics. The topics were (A) patient selection, (B) diagnostic tests necessary for patient selection and (C) how to perform SPB. For each question the consensus rate was calculated. Consensus was defined as at least 80% agreement between participants. Results: Eighteen participants completed all three rounds of the Delphi study. Nine participants were involved with SPB of 25 patients or less, nine with 25 to more than hundred patients. Consensus was reached in 52% of topic A, in 50% of topic B, and in in 22% of topic C. Relevant outcome results of the different topics with the related remarks will be discussed. Conclusions: The group was able to find consensus on less than half of the topics. Most consensuses were reached on topics involving patient selection and diagnostic tests, where participants relied on their experience of daily practice. However, the majority of the participants had limited experience in the way to perform the salvage treatment in which is probably the reason for more disagreement between participants compared to the two other topics. This study provides useful information on issues of uncertainty and disagreement that needs to be resolved in future trials. Poster Presentations ~1~
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